Clinical trials: Fragility
Fragility Fracture
The Role of Augmented Fixation Techniques in Fragility Fracture Pelvis (FFP)
Assessment of the role of augmented fixation of fragility fracture pelvis in improving functional outcome as a primary outcome and improving union and decreasing mortality and complications as secondary outcomes at 6 months and…
- Trial name
- NCT05837182
- Testing
- augmented fixation techniques
- Volunteers
- 30 people
- Sponsor
- Assiut University
Osteoporosis
Opportunistic Fragility Fracture Risk Estimates From Radiographs
The proposed study will predict a patients' risk of having osteoporosis by using a combination of the IBEX BH (Bone Health) software outputs and other clinical risk factors such as age, gender, medical history and lifestyle.
- Trial name
- OFFER2 (NCT06110442)
- Testing
- IbexBH Software
- Where
- United Kingdom
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Osteoporosis, Fracture
Fragility Fracture Liaison Service Project
Aims: to Establish the FLS services at the National Taiwan University Hospital (NTUH) and its Beihu Branch (BB). Method: From Jan., 2014, two related fracture liaison services (FLSs) following the 13 'Capture the Fracture Best…
- Trial name
- NCT02194660
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- National Taiwan University Hospital
Cardiac Infarct, Cardiac Valve Disease
Frailty, Physical Capacity and Lung Function in Postoperative Cardiac Surgery Patients
The goal of this observational and prospective study is to investigate changes in physical performance, lung function, and respiratory and peripheral muscle strength in patients during the postoperative period following coronary…
- Conditions
- Cardiac Infarct, Cardiac Valve Disease, Fragility, Physical Disability
- Trial name
- NCT06247358
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo General Hospital
Femur Fracture
Post-operative Anemia in Lateral Fractures of the Femur.
It was conducted a prospective study with a series of 45 patients with lateral fragility fractures of the femur treated by three different intramedullary nails.
- Trial name
- NCT05225753
- Testing
- hemoglobin serum value
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Sacral Fracture
Operative vs Non-Operative Treatment of Sacral Fractures
The purpose of this study is to compare percutaneous trans-iliac trans-sacral screw fixation to non-operative management for the treatment of symptomatic, sacral fragility fractures in elderly patients.
- Trial name
- NCT04044300
- Testing
- Single screw fixation, Conservative
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- More Foundation
Fragility
Geriatrician-performed Comprehensive Geriatric Care in an Outpatient Community Rehabilitation Unit
Introduction: Older adults with multiple illnesses represent the fastest growing sector of society and make increasing demands on all sectors of the health care system, particularly in outpatient community rehabilitation units…
- Trial name
- GCGCCRU (NCT01506219)
- Testing
- Geriatrician-performed CGC
- Where
- 2 sites in Denmark
- Volunteers
- 368 people
- Sponsor
- Aarhus University Hospital
Skin Condition, Hair Fragility
Assessment of Anti-aging Efficacy of Marine Collagen Peptides
To assess the anti-aging efficacy of Marine Collagen Peptides on skin, hair and finger nails for human
- Conditions
- Skin Condition, Hair Fragility, Nails, Ingrown
- Trial name
- NCT06306105
- Testing
- Marine Collagen Peptides
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Hip Fractures
The Effects of Fragility Fracture Integrated Rehabilitation Management
To determine the effects of Fragility Fracture Integrated Rehabilitation Management approach in geriatric hip fracture patients (post surgical)
- Trial name
- NCT04760756
- Testing
- Fragility Fracture Integrated Rehabilitation Management
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Zohra Institute of Health Sciences
Fragility, Physical Disability
Exercise Intervention in Institutionalized Elderly People
Questions: Does an evidence-based exercise program increase activities of daily living and physical fitness in institutionalized older adults? Does this program decrease the care dependency of institutionalized older adults?…
- Trial name
- BENENFIT (NCT01646632)
- Testing
- Physical exercise intervention, Lifestyle counseling
- Where
- Netherlands
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Hanze University of Applied Sciences Groningen
Hip Fractures
Structured Tailored Rehabilitation After Hip Fragility Fracture
Why the investigators are doing this study? The best approach to rehabilitation after a broken hip is not known. A new approach could improve outcomes by tailoring rehabilitation to patient needs.
- Trial name
- STRATIFY (NCT06014554)
- Testing
- Low-risk subgroup, Medium-risk subgroup, High-risk subgroup
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- King's College London
Old Age; Debility
Effectiveness of 8 Week Multicomponent Exercise Program in Older Adults With Frailty and Cognitive Impairment
Multicomponent exercise program in a frail population. It is analyzed whether there is an improvement in different parameters of the daily life of the study subjects, analyzing the variables of: physical condition, fragility…
- Trial name
- GERYPHYSIO (NCT06440733)
- Testing
- Multicomponent exercise program focused in elderly.
- Where
- Spain
- Volunteers
- 17 people
- Sponsor
- University of Malaga
Fragility
Determinants of Frailty Among of Informal Caregivers of Demented Patient
Frailty, a transitional state between successful and pathological aging, may be benefit from early multi-interventional intervention. Fried's criteria are the more commonly used criteria to diagnose frailty.
- Trial name
- DELFAF (NCT03994562)
- Where
- 2 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gérond'if
Chronic Thromboembolic Pulmonary Hypertension, Physical Disability
Frailty, Physical Capacity and Lung Function in Postoperative Pulmonary Endarterectomy Patients
The goal of this observational and prospective study is to investigate changes in physical performance, lung function, respiratory and peripheral muscle strength in patients during the postoperative period following pulmonary…
- Conditions
- Chronic Thromboembolic Pulmonary Hypertension, Physical Disability, Fragility
- Trial name
- NCT06286891
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
Hip Fractures
Fragility Fracture Integrated Rehabilitation Management (FIRM)
A number of studies for clinical pathway (CP) after hip fracture have been suggested to improve post-fracture outcome. However, CP is not carried out properly in most countries due to inadequate system and awareness, and lack of…
- Trial name
- FIRM (NCT03430193)
- Testing
- FIRM, Conventional rehabilitation
- Where
- South Korea
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Aged, Aged Subject
CREM - Clinical and Functional Outcomes in a Controlled Clinical Trial with Older Adults
To evaluate and compare the effects of different types of physical exercise on clinical and functional outcomes in the elderly. 240 community-dwelling elderly individuals of both sexes, sedentary, will be recruited for twelve…
- Trial name
- CREM (NCT06638697)
- Testing
- Free walking, Nordic walking, Dance
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Osteoporosis in Post-menopausal Women
Efficacy of Romosozumab and Denosumab Combined Treatment in Postmenopausal Osteoporosis Patients with Multiple Fragility Fractures
The aim of this clinical trial is to investigate the effectiveness of romosozumab started without stopping denosumab in patients diagnosed with postmenopausal osteoporosis with a very high risk of fragility fractures and who is…
- Trial name
- MORD (NCT06720350)
- Testing
- Romosozumab and Denosumab Combination Therapy, Romosozumab Prefilled Syringe [Evenity], Denosumab (Prolia)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Type1diabetes
Skeletal Fragility in Type 1 Diabetes: Glycemic Control and Bone Strength
The purpose of this research study is to find out how bones are affected in children and adolescents with type 1 diabetes (T1D) as compared to children and adolescents without type 1 diabetes.
- Trial name
- NCT04289727
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Columbia University
Osteopetrosis
rhPTH Therapy for Low Turnover Bone Fragility
The purpose of this study is to determine how treatment with a new medication, recombinant human parathyroid hormone (rhPTH) affects calcium balance and bone strength.
- Trial name
- NCT00145886
- Testing
- rhPTH
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Chicago
Frailty, Frailty Syndrome
Prevalence, Determinants and Natural History of Frailty and Pre-frailty in Elderly People
Frailty syndrome (i.e. frailty) is a geriatric syndrome which relies on the reduction of multisystem reserve capacity. Frail people have a lower potential to respond to external stressors and various life incidents as well as…
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome, Fragility
- Trial name
- FRAILPOL (NCT04518423)
- Where
- Poland
- Volunteers
- 1,093 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology