Clinical trials: Fractures
Infection, Closed Fractures
Prevention of Infection in Closed Fractures: Cefazolin Versus Vancomycin
The purpose of this study is to compare the incidence rate of infection in surgical patients with closed fractures treated prophylactically with Cefazolin versus Vancomycin in the peri-operative period.
- Trial name
- NCT02027532
- Testing
- Cefazolin, Vancomycin
- Where
- United States
- Volunteers
- 430 people
- Sponsor
- University of Tennessee
Ankle Fractures
Fibular Nail vs Plate in Ankle Fractures
Randomised Controlled Trial to Compare the Efficacy of Fibular Nail Fixation vs Plate Fixation in Ankle Fracture Management
- Trial name
- NCT04303663
- Testing
- Fibular Plate, Fibular Nail
- Sponsor
- Chinese University of Hong Kong
Trauma
Syndesmotic Injury and Fixation in Supination-External (SE) Ankle Fractures
The aim of our study was to determine whether transfixation of unstable syndesmosis is necessary in supination-external rotation type ankle fractures.
- Trial name
- NCT01234493
- Testing
- fixation, no fixation
- Where
- Finland
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Distal Radius Fracture
Effects of Action Observation Therapy and Motor Imagery Administered During Immobilization Period After Surgical Fixation of Distal Radius
The goal of this trial is to verify the effectiveness of Motor Imagery and Action Observation Training in subjects undergoing surgery for distal radius fracture fixation.
- Trial name
- NCT05867199
- Testing
- Motor Imagery and Action Observation Training
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituto Clinico Humanitas
Osteoporosis, Diagnoses Disease
Normative Database for HR-pQCT-Based Radius and Tibia Strength
A novel methodology was recently developed and validated by the applicants to compute bone strength at the distal radius and tibia using second-generation HR-pQCT reconstructions.
- Conditions
- Osteoporosis, Diagnoses Disease, Fracture, Bone Strength
- Trial name
- NODARATIS (NCT03219099)
- Where
- Switzerland
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Zygomatic Arch Fracture
Ultrasound Guided Closed Reduction of Depressed Zygomatic Arch Fractures
Zygomatic arch fractures have always been treated with blind closed reduction and is the most commonly used method. Blind reduction of fractures might lead to inadequate reduction and associated complications of facial asymmetry…
- Trial name
- NCT04528264
- Testing
- Intraoperative ultrasound guided, Conventional blind reduction technique
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- College of Medical Sciences Teaching Hospital. Nepal
Patellar (or Kneecap) Instability and Mal-alignment
CT Analysis of the Patellofemoral Joint in Patients Having Knee Surgery
The primary hypothesis is that measures of patellofemoral alignment obtained from the investigational cone beam CT scanner will be reduced, but still correlated to those obtained from the conventional CT scan.
- Trial name
- PF (NCT02257099)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- State University of New York at Buffalo
Rheumatoid Arthritis, Osteoarthritis
An Electronic Data Capture Study to Assess the Long-term Performance of the DePuy PROXIMA™ Hip in Primary Total Hip Replacement
The purpose of this study is to monitor the performance of the DePuy PROXIMA™ hip in the treatment of patients with hip joint disease requiring a total hip replacement.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Avascular Necrosis
- Trial name
- NCT01134445
- Testing
- DePuy Proxima™ Hip
- Where
- 4 sites in France, Portugal and 2 more
- Volunteers
- 42 people
- Sponsor
- DePuy International
Hip Fractures (ICD-10 72.01-72.2), Home Care, Hospital-Based
Home Rehabilitation After Hip Fracture
This study will examine whether a home-based rehabilitation program can help older adults recover after surgery for a hip fracture.
- Conditions
- Hip Fractures (ICD-10 72.01-72.2), Home Care, Hospital-Based, Home Care Services
- Trial name
- RECADO (NCT07478445)
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Hip Fractures, Venous Thromboembolism (VTE)
Delivery and Implementation of a Randomised Crossover Trial on Thrombosis
What is the Study About? The DIRECT study (Delivery and Implementation of a Randomised Crossover Trial on Thrombosis) is a large research project investigating the best way to prevent blood clots (thrombosis) in people who break…
- Trial name
- DIRECT (NCT06937372)
- Testing
- Patients in hospitals allocated to this arm will receive aspirin as their routine thromboprophylaxis after surgery., Low molecular weight heparin (LMWH)
- Where
- United Kingdom
- Volunteers
- 21,194 people
- Sponsor
- Queen Mary University of London
Osteoporosis
Study in Patients With Osteoporosis and Fragility Fractures to Estimate the Extent and Impact of Delayed Administration of Anti-fracture Therapy
Osteoporosis (OP) and fragility fractures are a significant problem that leads to morbidity, mortality, and high costs for the National Health System.
- Trial name
- OPGAP01 (NCT07512453)
- Where
- Italy
- Volunteers
- 8,000 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Hip Fractures
Effects of Music on Acute Postoperative Pain Intensity and Mobility After Fragility Hip Fracture
Music has been proven to be beneficial in postoperative care by reducing pain. The effects of music listening to reduce pain postoperatively are well studied among cases undergoing elective orthopaedic surgery.
- Trial name
- NCT06277102
- Testing
- music listening
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Hospital Authority, Hong Kong
Lateral Condyle Humerus Fracture in Children
Kirschner Wires Fixation Versus Cannulated Screws Internal Fixation for Displaced Lateral Condyle Humeral Fracture in Children
Lateral condyle fracture of the distal humerus is the second most common injury around the elbow and accounts for 20% of all the elbow fractures in children.The average age for the fracture involving the lateral condyle is around…
- Trial name
- NCT05409053
- Testing
- open reduction, Closed reduction, Conservative management
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Femoral Fracture, Cognition Disorders
Influence of Intrathecal Dexamethasone Administration for Proximal Femoral Fractures
Spinal anesthesia blocks acute pain in older patients with femur fracture. Delirium is a common complication seen after femur fracture, affecting approximately 10-16% of patients.
- Conditions
- Femoral Fracture, Cognition Disorders, Cortisol; Hypersecretion
- Trial name
- NCT03856502
- Testing
- 8 mg of dexamethasone, 12,5 mg of 0,5 % of levobupivacaine
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- General Hospital Sveti Duh
Rib Fractures, Oxygenation
Deep Breathing Exercises and Incentive Spirometry After Rib Fracture
Chest trauma patients constitute approximately 10-15% of all traffic accidents. Many complications may occur after chest trauma, including rib fracture, pneumothorax, hemothorax, lung contusion, flail chest, atelectasis…
- Trial name
- NCT06853002
- Testing
- Breathing exercise with spirometry, Breathing exercise with deep breathing method
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Samsun University
Postoperative Opioid Requirements in Patients With Traumatic Fracture Hip
Fascia Iliaca Versus Quadratus Lumborum Block for Pain Management in Total Hip Replacement.
Postoperative analgesia is essential for early ambulation of patients with hip arthroplasties as well as decreasing hospital stay time.
- Trial name
- NCT05504525
- Testing
- Fascia Iliaca block, Quadratus lumborum block
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Ain Shams University
Hip Fractures, Abdominal Surgery
Validation of Two Acitivity Monitors in Three Inpatient Populations.
The aim of this study is to investigate the validity of Sens Motion and ActivPAL acitivity monitors. Thirthy-six patients from three different patient populations will be included: 12 acute high-risk abdominal surgery patients…
- Conditions
- Hip Fractures, Abdominal Surgery, Medical Patients
- Trial name
- NCT04120740
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Mette Merete Pedersen
Weight-bearing, Rehabilitation
Influence of an Anti-gravity Treadmill on Functional Outcome in Non-operatively Treated Pelvic Fractures - a Pilot Study
Non-operative treatment of pelvic fractures is possible. Immobilisation implies different adjustment processes. Patients with pelvic ring fractures and partial weight bearing have to obtain theses.
- Trial name
- NCT03206398
- Testing
- anti-gravity treadmill
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Pneumothorax, Pleural Effusion
Multicenter Validation Study of an Artificial Intelligence Tool for Automatic Classification of Chest X-rays
A current problem in Radiology Departments is the constant increase in the number of studies performed. Currently the largest volume of studies belongs to plain x-rays.
- Conditions
- Pneumothorax, Pleural Effusion, Bone Fracture, Consolidation
- Trial name
- NCT04991987
- Where
- Argentina
- Volunteers
- 385 people
- Sponsor
- Hospital Italiano de Buenos Aires
Acetabular Fracture, PROMs
The Utility of Mobile Based Patient Reported Outcome Measures in Patients With Acetabular Fractures: A Randomized Controlled Trial.
Acetabular fractures are articular fractures involving the hip joint that needs anatomical reduction and a strict long follow up after fixation.
- Conditions
- Acetabular Fracture, PROMs, Mobile Phone Use
- Trial name
- NCT04393571
- Testing
- Mobile application
- Volunteers
- 138 people
- Sponsor
- Assiut University