Clinical trials: Fractures
Bone Fracture
Digital Three-dimensional Imaging Models for Repair of Complex Long Bone Fractures
To verify whether digital three-dimensional model-assisted internal fixation can obtain better effects in the repair of complex long bone fractures compared with conventional internal fixation.
- Trial name
- NCT02964754
- Testing
- CT scan for internal fixation, conventional internal fixation
- Volunteers
- 63 people
- Sponsor
- Qinghai University
Cervical Spine Fractures, Cervical Spine Injury
Study on Orthosis in Cervical Spine Fracture Treatment
Background and Purpose: Neck fractures affect over 1,100 people in Sweden each year, with the majority being frail older adults.
- Conditions
- Cervical Spine Fractures, Cervical Spine Injury, Rigid Collar
- Trial name
- SOFT (NCT06848660)
- Testing
- A rigid cervical collar
- Where
- 6 sites in Sweden
- Volunteers
- 616 people
- Sponsor
- Uppsala University Hospital
Scapular Fracture
Operative Management of Scapular Fractures
Assessment of functional outcome of operative management of scapular fractures through Arabic version DASH score
- Trial name
- NCT05982327
- Testing
- ORIF
- Volunteers
- 20 people
- Sponsor
- Assiut University
Fracture Femur, Fracture Tibia
Standard Versus Short Course Prophylactic Antibiotic in Femur and Tibia Shaft Fractures Managed With Intramedullary Interlocking Nail
Long-bone fractures, particularly of femur and tibia, are common following fall injury and road traffic accidents.1,2 The standard treatment is "intramedullary nailing," where a metal rod is inserted into the center of the bone…
- Conditions
- Fracture Femur, Fracture Tibia, Surgical Site Infection (SSI), Antibiotic
- Trial name
- NCT07554079
- Testing
- Short Course Antibiotics, Standard Course Antibiotics
- Where
- Nepal
- Volunteers
- 56 people
- Sponsor
- Kathmandu University School of Medical Sciences
Femoral Neck Fractures
Comparison of the Direct Anterior Approach (DAA) and the Direct Lateral Approach (DLA) in Patients Treated With Partial Hip Replacement for Femoral Neck Fracture Based on Postoperative Functional Status
The goal of this clinical trial is to learn whether the surgical approach used for hemiarthroplasty can improve clinical and functional outcomes in adults with displaced femoral neck fractures.
- Trial name
- NCT07501741
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Tibial Fractures, Open Fracture of Tibia
Intramedullary Nailing Versus External Fixation in Open Tibia Fractures in Tanzania
The investigators propose to undertake a randomized, controlled trial which will generate Level 1 evidence concerning optimal fixation methods for the treatment of severe open tibia fractures in Dar es Salaam, Tanzania.
- Conditions
- Tibial Fractures, Open Fracture of Tibia, Trauma
- Trial name
- NCT03861624
- Testing
- Intramedullary nailing with standard SIGN nail, External Fixation with uniplanar Dispofix external fixator
- Volunteers
- 240 people
- Sponsor
- University of California, San Francisco
Hypertension, Hemodynamic Response
Dexmedetomidine in Attenuation of Haemodynamic Response to Laryngoscopy in Controlled Hypertensive Patients
This randomized control trial, which was carried out at Sindh Institute of Urology and Transplantation (SIUT), used a non-probability consecutive sampling technique for six months from January 1, 2025, to June 30, 2025.
- Conditions
- Hypertension, Hemodynamic Response, Anesthesia
- Trial name
- NCT07557680
- Testing
- Dexmedetomidine, Normal Saline
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Sindh Institute of Urology and Transplantation
Tibia Fracture, Knee Pain Chronic
Knee Pain After Intramedullary Nailing in the Tibia
The primary objective of this study is to evaluate the long-term outcome after inserting an intramedullary nail in patients with a tibial shaft fracture using an injury-specific questionnaire.
- Trial name
- NCT03649360
- Where
- Denmark
- Volunteers
- 223 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Distal Radius Fracture
Motor Imagery in Rehabilitation After a Distal Radius Fracture
The aim of this study is to determine whether motor imagery training during the immobilisation period in patients with a distal radius fracture, results in an improved functional outcome compared to patients who do not perform…
- Trial name
- MIDRF (NCT01921062)
- Testing
- Motor imagery
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- University Medical Center Groningen
Bone Marrow, Femoral Shaft Fracture
Autologous Bone Marrow Concentration for Femoral Shaft Fracture Union
This study aims to evaluate the effect of bone marrow concentration on union of femoral shaft fracture by comparing clinical and imaging outcomes between patients receiving Intramedullary nail fixation with intraoperative bone…
- Trial name
- NCT03794622
- Testing
- intramedullary nail fixation with bone marrow concentration, intramedullary nail fixation
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Pei-Yuan Lee, MD
Hemorrhagic Shock, Pelvic Fractures
Hemorrhagic Shock in Orthopedic Fractures
The goal of this observational study is to learn about the incidence and predators of hemorrhagic shock in patients with Long bone and pelvic fractures .The main question it aims to answer is: In which bone fracture the…
- Conditions
- Hemorrhagic Shock, Pelvic Fractures, Long Bone Fractures
- Trial name
- NCT07695129
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Sohag University
Fracture Resistance
An In Vitro Evaluation of Fracture Resistance of Endodontically Treated Teeth Restored With New Contemporary Core Build-up Materials
Endodontic treatment is performed frequently which often results in weakening of tooth structure. Coronal restoration is done to restore these endodontically treated teeth.
- Trial name
- NCT05079646
- Testing
- class 1 and class 2 cavity preparation and restored with contemporary materials
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Degenerative Disease, Fracture
Early Mobilisation in the Surgical Robot Assisted Spinal Surgery
In this study, patients who underwent lumbar spine surgery in our hospital were included. A prospective study was conducted to investigate the effects of early mobilisation on postoperative complications, functual outcomes and…
- Trial name
- NCT04133103
- Testing
- first ambulation at 4 hour after operation
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Beijing Jishuitan Hospital
Carpometacarpal; Dislocation
Carpometacarpal Fracture-dislocations
Fracture-dislocation of the carpometacarpal (CMC) joints of the ring and little finger are the most affected CMC joints and the dislocation may be accompanied by other hand injuries.
- Trial name
- Dislocation (NCT04668794)
- Testing
- Osteosynthesis
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Extremity Injury
Upper Extremity Post-op Splints: Do They Improve Post-operative Pain?
The goal of this study is to determine if applying a rigid splint helps to reduce pain following operative fixation of upper extremity fractures.
- Trial name
- NCT03891966
- Testing
- Rigid Splint, Soft Dressing
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- NYU Langone Health
Fracture of Shaft of Humerus
Acute Management of Humeral Shaft Fractures: Sling vs. Splint
When people break their arm and arrive at Oregon Health and Science University's Emergency Department (OHSU ED), they are treated with a short-term means of immobilizing their broken arm.
- Trial name
- NCT01869322
- Testing
- Sling and Swathe, Coaptation Splint
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Oregon Health and Science University
Rib Fracture Multiple
Multicenter RCT of SSRF in Non Flail Patients
This study evaluates the efficacy of surgical stabilization of rib fractures, as compared to best medical management, for patients with multiple, displaced rib fractures.
- Trial name
- CWISNONFLAIL (NCT03221595)
- Testing
- Operative
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Denver Health and Hospital Authority
Hip Fracture, Anemia
Study of the Effect of Tranexamic Acid Administered to Patients With Hip Fractures. Can Blood Loss be Reduced?
The effect of Tranexamic acid on blood loss, hemoglobin and transfusions in patients with pertrochanteric hip fractures. Tranexamic acid is a well known drug used in many types of surgery.
- Trial name
- NCT01535781
- Testing
- Tranexamic Acid
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Hvidovre University Hospital
Osteoporotic Fractures
Cortical Bone Assessment Using Ultrasonic Guided Waves: Towards a Robust Clinical Measurement
Osteoporosis is a skeletal disease leading to bone fragility and increasing the risk of fractures and still remains a major public health problem worldwide.
- Trial name
- BDATChile (NCT05424536)
- Testing
- Bone measurement by DXA and ultrasound
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Hip Fractures
Optimization of Analgesia for Hip Fracture Patients
Hip Fracture is a common orthopedic emergency in elderly people, which causes moderate to severe pain. Until now, different methods of pain treatment have been used, including pain-killer medication, which given in to the vein…
- Trial name
- NCT03609645
- Testing
- Fascia iliaca block, Femoral articular branches block(FAB)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto