Clinical trials: Fracture, Knee
Osteoarthritis, Knee Injuries
Knee Osteoarthritis in the Region of Norrbotten
The goal of this observational study is to assess the prevalence of radiographic knee osteoarthritis and to report medium and long term functional outcomes secondary to tibia plateau fractures.
- Conditions
- Osteoarthritis, Knee Injuries, Knee Osteoarthritis, Tibial Plateau Fractures
- Trial name
- KORN (NCT06451510)
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- Umeå University
Gene Abnormality, Meniscus Injury
Study on Susceptibility Genes of Anterior Cruciate Ligament, Patella Dislocation and Discoid Meniscus
Genomes of all sports medicine-related genes will be exome sequenced to find relevant gene mutations. To further study the molecular mechanisms and signaling pathways related to sports injury.
- Conditions
- Gene Abnormality, Meniscus Injury, Cruciate Ligament Rupture
- Trial name
- NCT04997538
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Spine Degeneration, Hip Arthritis
Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation
This study aims to evaluate the effectiveness of a mobile application in improving postoperative rehabilitation outcomes among patients undergoing orthopedic surgery.
- Conditions
- Spine Degeneration, Hip Arthritis, Knee Osteoarthritis, Hip Fractures
- Trial name
- NCT06407427
- Testing
- App for in-bed conditioning exercises, Usual care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Fracture of Calcaneus, Pilon or Tibial Plateau
Vacuum Assisted Closure as a Treatment for Soft Tissue Injuries
This project is designed as a prospective, randomized, comparative study evaluating the use of a negative pressure vacuum device in treating soft tissue injuries and the surgical incision following open reduction and internal…
- Trial name
- VAC-ST (NCT00582998)
- Testing
- Standard Wound Dressing, Vacuum Assisted Closure Device
- Where
- United States
- Volunteers
- 249 people
- Sponsor
- University of Alabama at Birmingham
Episodic Patellar Dislocation
Medial Patellofemoral Ligament Reconstruction With or Without Lateral Retinaculum Release
The investigators hypothesis is lateral retinaculum release has no effect on treatment of Patellar Recurrent Dislocation with Medial Patellofemoral Ligament (MPFL) reconstruction.
- Trial name
- NCT01719666
- Testing
- MPFL reconstruction and lateral retinaculum release, conventional surgery
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Hospices Civils de Lyon
Hip Fractures, Knee Fracture
The Impact of Patient Safety Incidents on Patients' Quality of Life
This study estimates the impact of patient safety events on QoL in elective surgery patients using a secondary data set
- Trial name
- NCT05464771
- Testing
- Surgery for hip and knee replacement
- Where
- United Kingdom
- Volunteers
- 395,346 people
- Sponsor
- Imperial College London
Arthropathy of Knee, Arthropathy of Hip
Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery
The purpose of this research study is to evaluate effects of respiratory strengthening exercises on breathing function, in people who have orthopedic surgery.
- Conditions
- Arthropathy of Knee, Arthropathy of Hip, Lower Extremity Fracture, Orthopedic Disorder
- Trial name
- NCT05381818
- Testing
- Daily Inspiratory Muscle Training (dIMT), Acute Inspiratory Muscle Training (aIMT), Standard of Care (SOC)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Florida
Knee Arthritis
Comparison Between Fixed- Versus Mobile-bearing TKA
The purpose of the study is to analyse the clinical and radiological results of a postero-stabilized TKA by using a mobile bearing versus fixed. Only patients with medial femorotibial arthritis will be included.
- Trial name
- NCT00435357
- Testing
- mobile-bearing TKA, fixed- bearing TKA
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Hospices Civils de Lyon
Femoral Fractures, Pelvic Fractures
Tactile Incentiviser Improves Partial Weight Bearing After Lower-Limb Surgery
Background: After lower-limb surgery, many patients are instructed to walk with only a fraction of their body weight on the operated leg (partial weight bearing).
- Conditions
- Femoral Fractures, Pelvic Fractures, Hip Fractures (ICD-10 72.01-72.2), Hip Arthroplasty
- Trial name
- NCT06989554
- Testing
- mechanical feedback insole, Standard physiotherapy without feedback device
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Università degli Studi dell'Insubria
Articular Cartilage Defect
Superiority of MACI® Versus Microfracture Treatment in Patients With Symptomatic Articular Cartilage Defects in the Knee
The objective of this trial is to demonstrate superior efficacy and safety of MACI compared with arthroscopic microfracture in the treatment of patients (aged 18 to 55 years) with symptomatic articular cartilage defects of the…
- Trial name
- SUMMIT (NCT00719576)
- Testing
- autologous cultured chondrocytes on porcine collagen membrane, Microfracture
- Where
- 20 sites in Czechia, France and 5 more
- Volunteers
- 144 people
- Sponsor
- Vericel Corporation
Tendinopathy, Epicondylitis
TENDOSHOCK-2010 Combination Therapy for Athletic Tendinopathies
Athletic tendinopathies of the upper and lower extremity are often therapeutically challenging. Colour and Power-Doppler-ultrasound visualizes pathological neovessels in painful tendons, which are associated with pain-mediating…
- Trial name
- TENDOSHOCK (NCT01185951)
- Testing
- Polidocanol, Focused extracorporeal shock wave therapy, Topical NO
- Where
- Germany
- Volunteers
- 114 people
- Sponsor
- Hannover Medical School
Patellar Tendinitis, Patella; Tendinitis
Addition of Ultrasound-guided Percutaneous Neuromodulation to Ultrasound-guided Percutaneous Electrolysis and Eccentric Exercises in Patellar Tendinopathy.
Patellar tendinopathy, or "jumper's knee," is a prevalent condition involving patellar tendon degeneration due to structural overuse, common among athletes, particularly males over 18 in sports like volleyball, basketball, or…
- Conditions
- Patellar Tendinitis, Patella; Tendinitis, Patellar Tendinopathy / Jumpers Knee
- Trial name
- NCT06685302
- Testing
- US-guided PNM, US-guided PE, EE
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Universidad de Zaragoza
Tibial Fractures, Anterior Knee Pain Syndrome
INfrapatellar Versus SUprapatellar Reamed Intramedullary Nailing for Fractures of the Tibia
This study will investigate the incidence and severity of anterior knee pain comparing two different approaches to tibial nail fixation; Infrapatellar versus percutaneous semi-extended suprapatellar incisions.
- Trial name
- INSURT (NCT02750072)
- Testing
- Infrapatellar Approach, Suprapatellar Approach
- Where
- 6 sites in Canada, Spain
- Volunteers
- 248 people
- Sponsor
- Fraser Orthopaedic Research Society
Postoperative Delirium
Study of Postoperative Delirium in Elderly People After Orthopedic Surgery
The purpose of this study is to investigate the possible relationship of microRNA and postoperative delirium.
- Trial name
- NCT02817386
- Testing
- interview
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zhongnan Hospital
Tendinopathy
Is There a Mechanistic Reason for the Response or Non-response to Isometric Exercise in Tendinopathy?
In early phase tendinopathy, isometric exercises are seen as ideal to provide pain relief to patients. This approach is mainly based on a paper by Rio et al (2016), where they found that isometric exercises of a certain load…
- Trial name
- NCT03848598
- Testing
- Evaluation of local tendon deformation
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Patella Fracture
Management Of Patellar Fractures By Craniofacial Mesh Plate Osteosynthesis Augmented by Screws
Patellar fractures are challenging orthopedic injuries. Fractures that result in disruption of the extensor mechanism led to significant functional deficits.
- Trial name
- NCT06205914
- Testing
- fixation of patella fractures by craniofacial mesh plate osteosynthesis augmented by screws
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Tendon Injuries, Tendinopathy
Identification of Early Changes in Patellar Tendinopathy Using Ultra-high Field Strength MRI
This project will investigate patellar tendon tissue (transmission electron microscopy of structure and protein analyses) coupled with magnetic resonance imaging (1.5T and 7T) from persons with i) chronic patellar tendinopathy…
- Conditions
- Tendon Injuries, Tendinopathy, Patella; Tendinitis
- Trial name
- 7TKnee (NCT04144946)
- Where
- Denmark
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Tibial Shaft Fracture, Tibial Plateau Fracture
Gene Expression in Lower Extremity Acute Traumatic Compartment Syndrome
The purpose of this study is to evaluate both genotypic differences and differences in local gene expression in individuals who develop acute traumatic compartment syndrome relative to control patients with at-risk lower…
- Trial name
- NCT05521958
- Testing
- Acute injury without compartment syndrome, Acute injury with compartment syndrome, Exertional compartment syndrome
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Utah
Tibial Plateau Fractures
EFFECT OF EARLY WEIGHT BEARING AND ACTIVE KNEE EXERCISES IN TREATMENT OF TIBIAL PLATEAU FRACTURES
This study will answer the following research questions: Are there any significant differences between combination of early active knee ROM exercises and weight bearing versus early passive ROM with delayed weight bearing on pain…
- Trial name
- NCT07251699
- Testing
- Early active exercises will be applied from the first day by the participation of the patient with the assistance of the physiotherapist
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tibial Plateau Fractures
Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau
The investigators are conducting this research study to find better ways of treating pain following knee surgery. There is a standard (accepted) approach, which involves injection of numbing medication into the area around the…
- Trial name
- NCT06639503
- Testing
- Bupivacain
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Chicago