Clinical trials: Food Reward
Roux-en-Y Bariatric Surgery
Investigation of the Effects of Obesity Surgery on Appetitive Behaviour
Among all the existing ways to treat obesity (lifestyle, pharmacological), Roux-en-Y gastric bypass (RYGB) surgery is currently the most effective.
- Trial name
- NCT02010385
- Testing
- Octreotide, Saline
- Where
- Ireland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Healthy
Food Intake Decisions
Functional Magnetic resonance study on the effect of cognitive context variables on the perception and valuation of food odorants and flavor.
- Trial name
- NCT03095833
- Testing
- Odors, Visual stimulation, Experimental Task
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Eating Behavior, Eating Habit
Young Adult Eating Habits
Most individuals with obesity become so before age 35 and adolescent's unhealthy dietary patterns, specifically high intake of ultra-processed foods and poor overall diet quality, may contribute to energy overconsumption and…
- Trial name
- YAEH (NCT05550818)
- Testing
- High Ultra Processed Food Diet, No Ultra Processed Food Diet
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Healthy, Brain Insulin Sensitivity
Long-Term Effects of Walnut Consumption on Brain Function
Rationale: Healthy foods, including mixed nuts, may improve brain function, which is essential for cognitive and metabolic health, and may contribute to improved food intake regulation.
- Conditions
- Healthy, Brain Insulin Sensitivity, Cerebral Blood Flow, Brain Vascular Function
- Trial name
- WalBrain (NCT07422220)
- Testing
- Walnuts
- Where
- Netherlands
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obesity
Crave Crush Neuroimaging Study
The purpose of the research is to test whether a gymnemic acids (GA) lozenge will reduce reward region response to intake of high-sugar food and ad lib candy intake and whether the GA lozenge reduced reward region response to…
- Trial name
- NCT02949102
- Testing
- Crave Crush
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Obesity
Effect of Acute Exercise on Food Intake and Energy Expenditure Following a Gastric Bypass
This pilot study will use a crossover design to explore the effects of acute exercise following bariatric surgery on food intake, energy expenditure, appetite, food reward, appetite hormones, and inflammatory response.
- Trial name
- ExoABari (NCT04348617)
- Testing
- Moderate exercise, Rest
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universite du Quebec en Outaouais
Obesity
Reward Mechanisms in Obesity
The study aims to investigate the effects of 3.0 mg of liraglutide on reward brain circuits in human obesity and to better understand its effects on weight loss (in patients without diabetes).
- Trial name
- LIRAOB (NCT03347890)
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Zoltan Pataky
Healthy Normal Weight
Meal Texture and Satiety
The aim of the present study is to compare the nutritional compensation between iso-caloric meals of various textures (liquid vs solid) in health young adults.
- Trial name
- FEED (NCT04041752)
- Testing
- SOLID, LIQUID_P, LIQUID_L
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Nutrition Intervention
Rewarding Healthy Food Choices: a Mobile Serious Game Intervention in Adolescents
The aim of this study is to conduct an outcome and process evaluation of the REWARD intervention, a serious game intervention using reward-based strategies as a main method to trigger healthy snacking in Flemish adolescents.
- Trial name
- REWARD (NCT02622165)
- Testing
- The REWARD serious game intervention
- Where
- Belgium
- Volunteers
- 1,463 people, healthy volunteers welcome
- Sponsor
- University Ghent
Appetitive Behavior, Obesity
Neural Mechanisms for Appetitive Responses to High Reward Foods
This study is aimed at understanding neuroendocrine responses to different types of sugars and how this influences feeding behavior among lean, overweight, and obese individuals.
- Trial name
- NCT02945475
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Children's Nutrition Intake
The Nutritional Effect of Parental Use of Food as a Reward
Control rules are common parental practices that use food as reward to encourage children to conduct parents' preferred behaviors.
- Trial name
- NCT02354157
- Testing
- no intervention
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- McGill University
Obesity
Investigation of the Effects of Bariatric Surgery on Taste Reward in Humans
The investigators hypothesize that some of these changes in the reduced appetite after surgery may be due to alterations in taste.
- Trial name
- NCT01531738
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity, Appetitive Behavior
Regulation of Energy Balance and Metabolism - Mechanisms Behind and Beyond Obesity and Weight Loss
The study aims to investigate homeostatic and hedonic mechanisms regulating appetite, energy balance and metabolism in obesity and the effects of three distinct obesity treatments on these regulatory mechanisms.
- Trial name
- BALANCE (NCT03550339)
- Testing
- SURG, DIET, HAES
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Healthy
Food Reward Processing in the Human Brain
The aim of this study is to investigate the influence of different metabolic states and hormonal satiety signalling on responses in neural reward networks.
- Trial name
- NCT03081585
- Testing
- Satiety State
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Heidelberg Medical Center
Overweight and Obesity
The Role of Altered Nutrient Partitioning in Food Reward
Obesity remains a public health epidemic despite substantial advances in treatment strategies and therapies in the last decade. Effective strategies to support maintenance of improved metabolic health and reduced body weight are…
- Trial name
- NCT05200845
- Testing
- Conditioned Stimulus + (CS+): Flavored beverage solution with 75 calories of sucrose, Conditioned Stimulus - (CS-): Flavored beverage solution with sweetness-matched sucralose, High-Fat Test Meal Inside a Metabolic Chamber
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Adiposity, Weight Loss
Dopaminergic Function and Food Reward
The broad aim of the study is to obtain a better understanding of alterations in mesolimbic reward pathways in adiposity based on the hypothesis of a hypofunctioning reward system in obesity.
- Trial name
- NCT01906411
- Testing
- Dopamine depletion vs. Balanced aminoacid drink
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Obesity, Childhood, Eating Behavior
Study of Brain, Reward, and Kids' Eating
Children from rural communities are at greater risk for obesity than children from more urban communities. However, some children are resilient to obesity despite greater exposure to obesogenic influences in rural communities…
- Trial name
- BRAKE (NCT05456516)
- Testing
- Food Rating
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Penn State University
Behavior, Eating
Effect of High-fat/High-sugar Diet on Food Reward Signaling
In this randomized, single-blinded basic research study, healthy normal-weight human participants are exposed to a high-fat/high-sugar (HF/HS) snack or a low-fat/low-sugar (LF/LS) snack twice a day for eight weeks in addition to…
- Trial name
- NCT05574660
- Testing
- High-Fat/High-Sugar (HF/HS) Diet, Low-Fat/Low-Sugar (LF/LS) Diet
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Max Planck Institute for Metabolism Research
Eating Behavior, Hunger
Effect of Consumption on Cognitive Processes
To get a better understanding of the interaction between metabolism, neural responses, cognitive processes and appetite the investigaters will examine the effect of food consumption on cognitive processes.
- Conditions
- Eating Behavior, Hunger, Inhibition, Functional Magnetic Resonance Imaging
- Trial name
- NCT03472703
- Testing
- Break-Lunch time
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Normal Weight Adults, Adults With Obesity
Validation of a French-version of the Leeds Food Preference Questionnaire in Normal Weight and Patients With Obesity
While Food reward is an important component of the appetite control to consider, there is actually no tool that has been developed in French to perform its evaluation.
- Trial name
- LFPQ-F (NCT04041830)
- Testing
- Visit 1, Visit 2
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand