Clinical trials: Focus
Focus: Long-term Retention of Gadolinium-based Contrast Agent
Long-Term Retention of Gadolinium in Bone
The main objective was to prospectively explore the potential for long-term retention of Gadolinium (Gd) in bones in patients who have received a single dose of Gadolinium-based contrast agents (GBCA) or multiple doses of the…
- Trial name
- NCT01853163
- Testing
- Gadolinium analysis in bone and tissue samples
- Where
- 16 sites in United States, Germany and 4 more
- Volunteers
- 92 people
- Sponsor
- Navitas Life Sciences GmbH
Focus in on Collecting Paired Specimens for Matrix Equivalency
Specimen Collection Study Protocol
The specimens collected will be used to evaluate matrix equivalency in an immunoassay in development for the detection of IgG or IgA or IgM antibodies to SARS - CoV2 in human serum.
- Trial name
- NCT04468386
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Biomerica
Main Focus: Gluten and Starch Digestibility
GlutDigest - Pilot Study
This is a pilot, feasibility study to evaluate, test and optimize sample analysis procedures and protocols before the full-scale, crossover study is conducted.
- Trial name
- GlutDigestP (NCT04489836)
- Testing
- Glutalytic®, DE111®, Meal A
- Where
- Ireland
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Deerland Enzymes
Focus: Bioequivalence
Bioavailability Study With Oral Single Dose Administration of Ethinylestradiol and Dienogest
Characterisation of relative bioavailability of Diena (Test) in comparison to Valette® (Reference) after single dose administration under fasting conditions Assessment of bioequivalence of Test vs.
- Trial name
- NCT01600274
- Testing
- Dienogest-Ethinyl Estradiol (test product), Dienogest-Ethinyl Estradiol (reference product)
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pharbil Waltrop GmbH
Study Focus 1:Glycaemic Index, Study Focus 2:Glycaemic Response
Blood Glucose and Insulin Responses to Snack Food Products
The purpose of this study is to assess the effects of added food ingredients, when baked into a snack food product, on glycaemic index of the product and glycaemic and insulinemic responses to the product in healthy adults.
- Conditions
- Study Focus 1:Glycaemic Index, Study Focus 2:Glycaemic Response, Study Focus 3:Insulinemic Response
- Trial name
- NCT01341769
- Testing
- Dietary Intervention
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mondelēz International, Inc.
Focus of Study is STEMI
Phase 2 Clinical Proof-of-Concept Study of the Cardioprotective Properties of Danegaptide in ST Segment Elevation Myocardial Infarction
This study explores the potential cardioprotective properties of danegaptide when administered to patients with ST-Segment elevation myocardial infarction.
- Trial name
- NCT01977755
- Testing
- danegaptide
- Where
- Denmark
- Volunteers
- 591 people
- Sponsor
- Zealand Pharma
Focus on Healthy Infants
Feeding Infant Formula With Added Probiotics and Whey Protein Concentrate
To evaluate the effects of feeding an infant formula containing L. paracasei ssp. paracasei strain F19 or Whey Protein Concentrate.
- Trial name
- NCT01755481
- Testing
- Probiotic, Whey protein concentrate
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Arla Foods
Focus of the Study is to Promote Healthy Hearing
Game to Improve Hearing Health Care Outcomes
The investigators are studying the educational potential of games, with the goal of developing a game to improve learning and promote healthy hearing behaviors.
- Trial name
- NoisyCity (NCT02946567)
- Testing
- Noisy City information about hearing health care, Generic Game
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Photozig, Inc.
Primary Focus: Adult Subjects Who Require PICC Placement
Electrocardiogram (ECG) Guided Peripherally Inserted Central Catheter (PICC) Placement
This study is designed to obtain information for design purposes on use of an ECG guided monitoring system to aid in the correct placement of PICC lines. There is no formal study hypothesis.
- Trial name
- NCT00742053
- Testing
- ECG-guided PICC placement
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- C. R. Bard
Focus on Transfusion Dependent Thalassemia Patients Who Are Inadequate Responders to Deferasirox > 35mg/kgQD
Deferasirox BID (Twice a Day) in Transfusion Dependent Thalassemia Patients With Inadequate Response to High Doses
This is an open label, single arm, and multicenter study. The study will include the following phases. A screening phase which lasts for 4 weeks to determine patient eligibility.
- Trial name
- NCT01948817
- Testing
- Deferasirox
- Sponsor
- Novartis Pharmaceuticals
No Specific Conditions Under Study. Primary Focus: Adult Subjects Who Require PICC Placement
Assessment of the Precision of the Sherlock 3CG Tip Positioning System
Phase I determine the location of the peripherally inserted central catheter (PICC) tip upon observation of maximum p-wave amplitude Phase II determine the precision of PICC placement in the Sherlock 3CG group versus the standard…
- Trial name
- STAT-PICC (NCT01275430)
- Testing
- Sherlock 3CG, Blind Placement
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- C. R. Bard
Focus of Study is Imaging Performance With the New Technology Compared With the Currently Available Technology.
Pilot Study Intended to Provide Input for Future Designs Using the PET Alpha Ring Detector
A standard PET/CT scanner is comprised of two different machines: An X-ray computed tomography scanner (CT), which gives information about your anatomy, and a Positron Emission Tomography scanner (PET) that provides information…
- Trial name
- NCT01731860
- Testing
- Additional PET Scan
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Philips Healthcare
Focus of the Study is on Gut Health
Effects of a Dietary Fiber on Fecal Microbiota and Metabolism
The purpose of the study is to examine how a dietary fiber affects metabolism in healthy overweight and obese adults. The fiber will be added to foods that participants will consume for two, three-week periods.
- Trial name
- NCT01518088
- Testing
- Dietary Fiber
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ingredion Incorporated
Focus: Assess Post Infusion Viability of S303 RBCs
A Study to Assess the Recovery and Lifespan of Radiolabeled Autologous S303 Treated Red Blood Cells
The objective of this study is to assess the post-infusion viability of S-303 Red Blood Cells (RBC) by measuring the 24 hour post-infusion recovery and lifespan of autologous RBCs prepared with the S-303 Treatment System for RBC…
- Trial name
- S303 RBC (NCT01711346)
- Testing
- S303 Red Blood Cells (RBCs), Conventional, untreated Red Blood Cells (RBCs)
- Where
- 2 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cerus Corporation
Focus of Study: Healthy Individuals
Effectiveness of a Well-being Web-based Intervention
The purpose of this study is to determine whether the intervention Daily Challenge (MeYou Health, LLC), a behavioral intervention delivered online, is effective in improving individuals' well-being.
- Trial name
- NCT01586949
- Testing
- Daily Challenge
- Where
- United States
- Volunteers
- 1,503 people, healthy volunteers welcome
- Sponsor
- MeYou Health, LLC
Focus:Use of S303 RBCs in Patients With Acute Anemia
Study to Assess S303 RBCs and Evaluate Safety and Efficacy in Patients Requiring Transfusion Support of Acute Anemia
The clinical study will assess the in-vitro characteristics of red blood cells (RBCs) per the European Union (EU) criteria for leukocyte depleted RBCs in additive solution and evaluate the safety and efficacy of S-303 treated…
- Trial name
- NCT01716923
- Testing
- S-303 Red Blood Cells (RBCs) - Test, Conventional, untreated red blood cells (RBCs) - Control
- Where
- 2 sites in Germany
- Volunteers
- 81 people
- Sponsor
- Cerus Corporation
Focus of Study: Radiolabel Recovery and Survival of RBCs
Inactivation of Whole Blood With Mirasol
The purpose of this study is to evaluate radiolabeled recovery and survival of autologous red blood cells (RBC), derived from Mirasol-treated fresh whole blood (WB), stored as leukoreduced packed RBC (LR-pRBC), and re-infused in…
- Trial name
- IMPROVEII (NCT01907906)
- Testing
- Mirasol System for Whole Blood
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Terumo BCTbio
Focus of the Study is Measuring Respiratory Rate
Respiration Rate V2.0 in Healthy Volunteers
The purpose of this study is to meet the respiration rate accuracy specifications for the study pulse oximeter monitoring system (study device)in a healthy volunteer population when compared to established technologies for…
- Trial name
- NCT01804062
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Conditions: None. Focus: Understanding the Obesogenic Potential of Fructose Containing Sugars
A Comparison of the Neurocognitive and Metabolic Effects of Fructose, Glucose, High Fructose Corn Syrup and Sucrose at Normal Population Consumed Levels in Adults Ages 20-60 Years Old
The purpose of this study is to investigate the acute and chronic effects of consumption fructose containing sugars and glucose in a real word setting when consumed in a manner and amount typical in the American diet.
- Trial name
- NCT02278042
- Testing
- Beverage Consumption
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Rippe Lifestyle Institute
Weight Loss, Appetite Modulation (Focus of Study)
Safety and Efficacy of IQP-AK-102 in Reducing Appetite
The individual ingredients in IQP-AK-102 have been widely used. Backed by data from several studies demonstrating their efficacy, we are conducting this study to look into the efficacy and safety of this novel combination of…
- Trial name
- NCT02041754
- Testing
- IQP-AK-102
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- InQpharm Group