Clinical trials: Fluid Loss
Muscle Loss, Extracellular Fluid Alteration
Ultrasound Detection of Body Composition in Critical Care
Objective assessment of the Changes in body composition of critically ill patients is very valuable. Ultrasound stands as a solution due to its portability, bedside availability, and radiation-free technology.
- Conditions
- Muscle Loss, Extracellular Fluid Alteration, Critical Illness, Pregnancy Complications
- Trial name
- NCT06728722
- Testing
- ultrasound detection of body composition
- Where
- Egypt
- Volunteers
- 121 people
- Sponsor
- Ain Shams University
Dehydration, Electrolyte Imbalance
Buoy Electrolyte Study on Hydration Status of Active Men and Women
Buoy is an all-natural, organic, FDA compliant dietary electrolyte supplement that can be dissolved in 8-12oz water (or other liquid) and provide electrolytes in servings of 1/3 teaspoon.
- Conditions
- Dehydration, Electrolyte Imbalance, Electrolyte Depletion, Fluid and Electrolyte Imbalance
- Trial name
- NCT05768789
- Testing
- Buoy Electrolyte, Water only, Nuun Electrolyte
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Androgenetic Alopecia
Cold Plasma to Treat Hair Loss
Self applied cold plasma activated medium used for androgenetic alopecia
- Trial name
- NCT04379752
- Testing
- Cold-atmospeheric pressure plasma activated aqueous-alcohol solution treatment
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Dr. Peter C. Friedman
Intermittent Fasting, Obesity, Morbid
Intermittent Fasting as a Means to Lose Fluid Overload and Weight in Complicated Obesity
To examine the feasibility of intermittent fasting (36h, twice a week, unlimited salt and calorie-free fluid consumption), over three months, on body weight and composition in complicated obesity in whom age and medical…
- Conditions
- Intermittent Fasting, Obesity, Morbid, Comorbidities and Coexisting Conditions, Weight Loss
- Trial name
- NCT04193995
- Testing
- Intermittent fasting
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obesity, Type 2 Diabetes Mellitus
Use of MCT Oil for Enhancement of Weight Loss and Glycemic Control in Obese Diabetic Patients
Phase I, 6 weeks: Intensive weight loss 42 obese subjects with type 2 diabetes mellitus or impaired fasting glucose (FBS greater than 100 mg/dl) and a patient at the Nutrition and Weight Management Center at Boston Medical Center…
- Trial name
- NCT00207233
- Testing
- MCT oil hypocaloric liquid diet, LCT hypocaloric liquid diet, Subcutaneous abdominal adipose tissue biopsy
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Boston Medical Center
Alzheimer Disease, Mild Cognitive Impairment
Study of Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of NIO752 in Early Alzheimer's Disease Participants
Phase 1b study to assess the pharmacodynamics, safety, tolerability, and pharmacokinetics of NIO752 in patients with early Alzheimer's disease (AD)
- Trial name
- NCT05469360
- Testing
- NIO752
- Where
- 10 sites in Finland, France and 2 more
- Volunteers
- 38 people
- Sponsor
- Novartis Pharmaceuticals
Fluid Loss
The Effect of Negatively Fluid Balancing Speed for ICU Patients With Acute Respiratory Distress Syndrome
Previous studies have shown that a positive fluid balance was an independent factor of worse prognosis in ICU patients with acute respiratory distress syndrome (ARDS), and negative fluid balance has been demonstrated to increase…
- Trial name
- NCT03552601
- Testing
- traditional speed, faster speed
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Qingdao University
Sudden Hearing Loss
The Effect of Patient's Position After Intra-tympanic Injection on the Amount of Fluid in the Middle Ear
During the regular protocol of Intra-tympanic injections of Dexamethasone to the middle ear due to Sudden Sensorineural Hearing Loss, the patients will be sitted once after the injection instead of lying down.
- Trial name
- NCT04449848
- Testing
- Sitting after intra tympanic injection
- Volunteers
- 20 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Partial Edentulism, Dental Implants
Comparison of Two Dental Implant Types and Placement Depths on Bone Around the Implant in Adults Missing Back Teeth
The goal of this clinical trial was to compare two ways of placing and restoring dental implants in adults missing one or more back teeth.
- Conditions
- Partial Edentulism, Dental Implants, Alveolar Bone Loss
- Trial name
- NCT07886762
- Testing
- issue-level implant placed at crestal level (Klockner Essential Cone), Bone-level implant placed 2 mm subcrestally with one-abutment-one-time protocol (Klockner Vega)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Markel Diéguez-Pereira
Alzheimer's Disease
Efficacy and Safety of Plasma Exchange With 5% Albumin in Beta-amyloid Peptide Clearance in Cerebral Spinal Fluid
The purpose of this study was to evaluate the efficacy and safety of plasma exchange with 5% albumin in beta-amyloid peptide clearance in cerebrospinal fluid, and its effects in patients with mild-moderate Alzheimer's disease.
- Trial name
- NCT00742417
- Testing
- Albutein 5%, Control
- Where
- 4 sites in United States, Spain
- Volunteers
- 42 people
- Sponsor
- Instituto Grifols, S.A.
MRI in Evaluation of Fecal Incontinence
Fecal Incontinence (FI) is a Debilitating Physical and Psychological Disorder Characterizedbytheinvoluntary Loss of Flatus or Liquid/Solid Stool.
Fecal incontinence (FI) is a debilitating physical and psychological disorder characterizedbytheinvoluntary loss of flatus or liquid/solid stool.
- Trial name
- NCT07898748
- Testing
- 3DendoanalultrasoundversusexternalphasedarrayMRI inevaluationoffecal Incontinence
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hypovolemia, Fluid Loss
Acetated Ringer´s Solution in Experimental Hypovolemia
Intravenous fluids are often given to increase stroke volume and thereby improve global oxygen delivery. The effect is however often transient, but the effect of a fluid bolus on stroke volume and other hemodynamic variables over…
- Conditions
- Hypovolemia, Fluid Loss, Hemodynamic Instability
- Trial name
- Volu-Flow (NCT05705115)
- Testing
- Ringer acetate, Lower body negative pressure
- Where
- Norway
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Type2 Diabetes
The Effect of Fasting on Serum Osmolarity in Diabetic Patients
In Ramadan, Muslims perform a special kind of fasting. Their fasting start with the first lights of the sunrise and end with the sunset.
- Trial name
- NCT04392570
- Testing
- Fasting
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Istanbul Medeniyet University
Hearing Loss, Cochlear, Cytomegalovirus Congenital
Cytomegalovirus (CMV) Perilymphatic Fluid
In France, children cochlear implantation (CI) is performed 400 times per year. Causes of profound sensorineural hearing loss (SNHL) are represented by congenital malformation of the inner ear for 50 to 60%.
- Trial name
- CMVP (NCT04724265)
- Testing
- collection of sample of perilymphatic fluid during cochlear implantation
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fluid Overload, Fluid Loss
Peroperative Fluid Management in Major Gynecological Cancer Surgeries
The aim of this study is to evaluate the effect of perioperative fluid management on postoperative kidney damage in gynecological cancer surgeries.
- Conditions
- Fluid Overload, Fluid Loss, Perioperative/Postoperative Complications, Acute Kidney Injury
- Trial name
- NCT06101498
- Testing
- Akut kidnet injury(AKI)
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Fluid Loss
Clinical Evaluation of the Zynex Monitoring System, Model CM-1600
This is a prospective, single-arm, non-randomized, non-controlled single-center study for the evaluation of the Zynex CM-1600 in 20 healthy adults undergoing a manual blood loss of up to 500mL followed by an infusion of 1 liter…
- Trial name
- NCT05740644
- Testing
- CM-1600
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zynex Monitoring Solutions
Periodontal Diseases, Periimplant Diseases
Markers of Bone Destruction and Oxidative Stress in Peri-implantitis
The aim of this study is to evaluate and compare the levels of bone resorption (RANKL, OPG) and oxidative stress (Nitrotyrosine, NQO1) markers, along with pro-inflammatory cytokines (IL-1β), in the saliva and peri-implant…
- Trial name
- NCT07397884
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Fluid Overload, Fluid Loss
Implementation of Fluid Strategies Using Real-time Bioelectrical Analyzer in Surgical Intensive Care Unit (SICU)
Precise assessment of postoperative volume status is important to administrate optimal fluid management. Bioelectrical impedance analysis (BIA) which measures the body composition using electric character.
- Trial name
- NCT06097923
- Testing
- Active fluid management with BIA monitoring, Conventional fluid management without BIA monitoring
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul St. Mary's Hospital
Periodontal Diseases, Periodontal Attachment Loss
Low-level Laser Therapy as an Adjunct to Non-surgical Periodontal Treatment
The present study aimed to investigate the effects of low-level laser therapy (LLLT) as an adjunct to non-surgical periodontal treatment (NSPT) on the plasminogen-activating system in Stage 3-4, Grade C periodontitis patients.
- Conditions
- Periodontal Diseases, Periodontal Attachment Loss, Periodontal Disease, AVDC Stage 3, Periodontal Inflammation
- Trial name
- NCT05233501
- Testing
- low level laser therapy, non-surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Obesity, Weight Loss
Use of MCT Oil for Enhancement of Weight Loss in Obese Patients
Twelve obese patients approved for gastric bypass surgery will be randomized to either receive an MCT-based or LCT-based liquid diet for a 4 week period. These diets will be identical except for the quality of the fat.
- Trial name
- NCT00207272
- Testing
- 1170-1870 kcal/day liquid diet, Gastric bypass surgery, Biopsy.visceral adipose tissue
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Boston Medical Center