Clinical trials: Flu Like Illness
Respiratory Infection
Unclogging the Pediatric Emergency Room: Impact of Rapid Viral Diagnostics
Acute respiratory tract infections are among the most common problems of childhood, particularly among infants and children younger than 3 years, and account for most antibiotic prescriptions to children.
- Trial name
- NCT00278759
- Testing
- Nasopharyngeal washing for viral antigen detection by immunofluorescence initiated early in ED visit.
- Where
- Canada
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Acute Respiratory Infection, Influenza-like Illness
Kent State University / Price Chopper Employee Wellness Study
This is a comprehensive randomized cluster hand-hygiene improvement intervention to reduce: self-reported acute respiratory tract infections (ARI) / influenza-like-illness (ILI) and gastrointestinal (GI) illness, absenteeism…
- Conditions
- Acute Respiratory Infection, Influenza-like Illness, Gastrointestinal Infection
- Trial name
- NCT03454009
- Testing
- Multimodal hygiene intervention
- Where
- United States
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Kent State University
Influenza, Influenza-like Illness
Adjuvanted Influenza Vaccination Year 2 Follow-On Survey
The purpose of this study is to determine if different influenza vaccines produce different outcomes in nursing facility residents receiving the required annual influenza vaccination.
- Conditions
- Influenza, Influenza-like Illness, Influenza, Human
- Trial name
- NCT03599739
- Testing
- Influenza
- Where
- United States
- Volunteers
- 598 people, healthy volunteers welcome
- Sponsor
- Insight Therapeutics, LLC
Influenza -Like Illness, Influenza (Healthy Volunteers)
Mucosal and Systemic Immunity Correlates of Protection Against Influenza in Young Children, Aged 2-5 Years (MUSIC-Flu)
Title: Mucosal and systemic immunity correlates of protection against influenza in young children (MUSIC-Flu). The goal of this observational study is to better understand how immune responses in the blood and mucosa are linked…
- Trial name
- MUSIC-Flu (NCT07861854)
- Where
- South Africa
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute for Communicable Diseases, South Africa
Influenza, Human
A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age
This study will compare an investigational mRNA flu vaccine with a licensed flu vaccine in adults 65 years of age and older. Participants will receive one injection and will be followed during the flu season.
- Trial name
- NCT07805707
- Testing
- mRNA Seasonal Flu vaccine, Licensed Influenza Vaccine
- Where
- 163 sites in United States
- Volunteers
- 54,000 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Influenza, Influenza-like Illness
Evaluation of Psychometric Testing Properties of Severity Symptom Grading Scale of Influenza Infection: Flu-PRO Stage III
There is no standardized method for evaluating the symptoms of influenza. A standardized instrument for measuring influenza symptoms, with appropriate scientifically derived content and construct validity would have value for…
- Trial name
- FluPRO3 (NCT02302924)
- Where
- 5 sites in United States
- Volunteers
- 535 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Influenza-like Illness, Influenza
REDucing Influenza Among University Students, University of California at Berkeley
We will be testing the hypothesis whether online education for UC Berkeley students on respiratory hygiene, cough etiquette, hand hygiene/awareness, as well as face mask use (while ill) will reduce the acquisition and…
- Trial name
- REDI-US (NCT00448773)
- Testing
- Online education
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
COVID-19, SARS-CoV-2
COVID-19 Pandemic Response Network
Coronavirus Disease 19 (COVID-19) represents an unprecedented challenge to the operations and population health management efforts of health care systems around the world.
- Conditions
- COVID-19, SARS-CoV-2, Coronavirus, Influenza -Like Illness
- Trial name
- NCT04320862
- Where
- United States
- Volunteers
- 9,207 people, healthy volunteers welcome
- Sponsor
- Duke University
Influenza
A Prospective Epidemiological Cohort Study Evaluating Occurrences of Influenza-like Illness.
This Prospective epidemiological cohort study is being conducted in order to generate epidemiological data in support of Osivax's clinical development of a broad spectrum influenza vaccine based upon the internal influenza…
- Trial name
- NCT05184387
- Testing
- Blood samples
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Osivax
Influenza
A Prospective Epidemiological Study Evaluating Occurrences of Influenza-like Illness
This prospective epidemiological cohort study is being conducted in order to generate epidemiological data in support of Osivax's clinical development of a broad-spectrum influenza vaccine based upon the internal influenza…
- Trial name
- NCT06779981
- Testing
- Nasopharyngeal swabs
- Where
- Belgium
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Osivax
Influenza Virus Infection, Influenza-like Illness
Direct and Indirect Benefits of Influenza Vaccination in Schools and Households
The purpose of this study is to determine the degree of indirect benefits to family members and classmates resulting from administration of influenza vaccine to children.
- Conditions
- Influenza Virus Infection, Influenza-like Illness, Acute Respiratory Infection
- Trial name
- NCT00981513
- Testing
- Trivalent live attenuated seasonal influenza vaccine, Monovalent live attenuated pandemic influenza vaccine, Saline
- Where
- Hong Kong
- Volunteers
- 6,300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Influenza, Influenza-like Illness
A Pragmatic Assessment of Influenza Vaccine Effectiveness in the DoD
A total of 18,000 eligible subjects (or 6,000 subject distributed evenly between the 3 study arms) will be enrolled. Eligible subjects will be randomized in 1:1:1 (cell-culture-based vaccine, the recombinant vaccine, or the…
- Conditions
- Influenza, Influenza-like Illness, Influenza Vaccines
- Trial name
- PAIVED (NCT03734237)
- Testing
- Egg based influenza vaccines, Recombinant influenza vaccines, Cell-culture based influenza vaccines
- Where
- 9 sites in United States
- Volunteers
- 15,448 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
SARS CoV-2 Infection, Influenza -Like Illness
A Trial of Two Mask Systems in Preventing SARS CoV-2 in Healthcare Workers (HCW)
A cluster randomized trial will be conducted to evaluate the difference between an Acteev™ system (Acteev™ N95 masks YQD8008 during shifts+ Acteev™ fabric masks in community) and a standard system (standard N95 masks during…
- Trial name
- NCT05036941
- Testing
- Acteev™ Masks, Comparison Masks
- Where
- India
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Ascend Performance Materials
Influenza, Influenza, Human
Baloxavir Versus Oseltamivir for Nursing Home Influenza Outbreaks
Influenza outbreaks are a prevalent event in nursing homes (NHs). We will study baloxavir compared to oseltamivir when used for influenza prophylaxis when facilities identify an index incident case of influenza.
- Conditions
- Influenza, Influenza, Human, Influenza -Like Illness
- Trial name
- NCT05012189
- Testing
- Oseltamivir, Baloxavir
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Insight Therapeutics, LLC
Influenza, Influenza -Like Illness
Broadening Our Understanding of Early Versus Late Influenza Vaccine Effectiveness
This study uses a prospective cohort design to investigate if the seasonal influenza vaccine is equally effective when given early and late before the proceeding influenza season.
- Trial name
- BELIEVE (NCT04570904)
- Testing
- Influenza vaccination at different time points
- Where
- United Kingdom
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Influenza -Like Illness, Influenza A
Home Testing of Respiratory Illness
The main goal of this research study is to use data from activity trackers (such as Fitbits), lab tests, and surveys to see if activity, sleep, and heart rate data can tell the difference between when someone has a respiratory…
- Conditions
- Influenza -Like Illness, Influenza A, Influenza Type B, Respiratory Viral Infection
- Trial name
- NCT04245800
- Where
- United States
- Volunteers
- 5,233 people, healthy volunteers welcome
- Sponsor
- Evidation Health
Patient With Influenza Like Illness
Effect of Influenza Vaccination of Healthcare Workers (HCW) on the Risk of Influenza in Patients Hospitalized in Short Stays Units
Hospital acquired influenza is associated with significant morbidity and mortality in hospitalized patients notably elderly patients. Vaccination of HCW is recommended to prevent influenza transmission in healthcare setting.
- Trial name
- NCT02198638
- Testing
- A nasal swab
- Where
- 2 sites in France
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Respiratory Tract Infections, Covid19
Vitamin D3 Supplementation to Prevent Respiratory Tract Infections
The Cooper vitamin D3 study is a randomized study investigating whether daily vitamin D3 supplementation can prevent respiratory tract infections, influenza-like illness and covid-19 in hospital workers.
- Conditions
- Respiratory Tract Infections, Covid19, Flu Like Illness
- Trial name
- NCT04596657
- Testing
- Vitamin D supplementation
- Where
- United States
- Volunteers
- 877 people, healthy volunteers welcome
- Sponsor
- Cooper Norcross Health
Influenza
Efficacy Study of Two Influenza Vaccines and Placebo in Healthy Adult Subjects
The present study will evaluate clinical efficacy, safety, tolerability and immunogenicity of both Novartis Vaccines' cell-derived influenza vaccine and egg-derived influenza vaccine in healthy adults 18 to 49 years of age.
- Trial name
- NCT00630331
- Testing
- Cell culture-derived influenza vaccine, Egg-derived influenza virus vaccine
- Where
- 56 sites in United States, Finland and 1 more
- Volunteers
- 11,404 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Influenza, Influenza -Like Illness
Recombinant Influenza Vaccination in U.S. Nursing Homes
Based on recent evidence on the mutation of the A/H3N2 strain in egg-grown vaccine, the investigators will study the quadrivalent recombinant influenza vaccine (RIV4, Flublok) compared to the standard dose quadrivalent vaccine…
- Conditions
- Influenza, Influenza -Like Illness, Influenza, Human
- Trial name
- NCT03965195
- Testing
- Recombinant Influenza Vaccine, Standard Dose Quadrivalent Influenza Vaccine
- Where
- United States
- Volunteers
- 1,989 people, healthy volunteers welcome
- Sponsor
- Insight Therapeutics, LLC