Clinical trials: Fistula;Rectal
Anal Fistulas, Anal Fistula
Identifying Landmark Factors of Anal Fistulas
The goal of this observational study is to understand the effects of anatomical factors, etiology, and complexity of anal fistula on the prognosis of patients undergoing anal fistula surgery within one year post-operation.The…
- Trial name
- NCT06421129
- Testing
- anal fistula surgery
- Where
- China
- Volunteers
- 326 people
- Sponsor
- Guanlin Liu
Fistula in Ano
Fistula-in-ano in Infants and Children
In this prospective, randomized trail, duration of non-cutting seton placement in patients with fistula-in-ano is evaluated.
- Trial name
- NCT05666609
- Testing
- placement of non-cutting seton (silicone)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Anal Fistula
Cross-cultural Adaptation of the Chinese Version of QoLAF-Q (Quality of Life in Patients With Anal Fistula Questionnaire) ：A Multi-center Study
The investigators verify the reliability and practicality of the Chinese adaptation results of QoLAF-Q, which helps Chinese doctors better master the methods and techniques of quality of life assessment.
- Trial name
- NCT06962228
- Testing
- Anal fistula surgery
- Volunteers
- 150 people
- Sponsor
- Changhai Hospital
Fistula-in-ano, Rectal Polyp
Trial on Use of Coloshield in Transanal and Anal Surgery
In various transanal and anal procedures it is desirable to clean the operating field from stool contamination. Thus mechanical bowel preparation is not well tolerated by patients. Enema does not provide sufficient effect.
- Conditions
- Fistula-in-ano, Rectal Polyp, Rectal Adenoma, Hemorrhoids
- Trial name
- NCT02579330
- Testing
- Coloshield, Control
- Where
- Switzerland
- Volunteers
- 22 people
- Sponsor
- Daniel Steinemann, MD
Fistula;Rectal
Fistula Laser Closure
The anal complex fistula constitutes a challenge in proctologic surgery because of the of its therapeutic care complexity due to the frequency of recurrences and the necessity to protect the sphincter function.
- Trial name
- NCT03297138
- Testing
- FiLAC laser
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Anal Fistula
Re-routing in Treatment High Anal Fistula
The aim of this study is to evaluate the role of rereouting in treatment of high anal fistula and evaluate the success rate, the recurrence and incontinence and see if rerouting of the track is a good choice in treatment of high…
- Trial name
- NCT05476146
- Testing
- Rerouting of the track in high anal fitula
- Volunteers
- 50 people
- Sponsor
- Assiut University
Anal Fistula, Complex Perianal Fistula
Evaluating an rhPDGF-BB-enhanced Collagen Plug for Perianal Fistula Healing
The average success rate for healing and remission of complex perianal fistulas, idiopathic or Crohn's-related, is approximately 50%.
- Trial name
- NCT06632418
- Testing
- RhPDGF-BB
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Alexander Hawkins
Fistula in Ano
Study Evaluating the Safety and Efficacy of an ECM Hydrogel for the Treatment of Anorectal Fistulas
Safety and Efficacy of ECMT-100 for the Treatment of Anorectal Fistulas
- Trial name
- NCT07035925
- Testing
- ECMT-100
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- ECM Therapeutics, Inc.
Fistula in Ano, Transsphincteric Anal Fistula
Treatment of Fistula in Ano With Autologous Fatty Tissue Cells Transplantation
This is a prospective interventional study on the treatment of transsphincteric fistula in ano. After abdominal or thigh liposuction, fat was injected around the fistula tract that was then transected percutaneously with a sharp…
- Trial name
- NCT04660903
- Testing
- Autologous fat cell transplantation
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Konstantinos Tsimogiannis
Fistula in Ano, Ano Fistula
The Impact of 3D Anal Fistula Models on Patient Understanding and Decision Making
An anal fistula is an abnormal communication between the luminal surface of the anorectal canal and the perianal skin. Fistulas can vary in their complexity and can be challenging to treat, due to the anatomical relation to the…
- Trial name
- 3DAF (NCT04069728)
- Testing
- Explanation with 3D printed fistula model, Standard explanation
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- London North West Healthcare NHS Trust
Anal Fistula, Crohn Disease
Management of Anal Fistula of Crohn Disease
The management of anal fistula in Crohn Disease is complex. In aim to obtain the healing of the anal fistula, different approaches can be proposed but the best strategy is not yet determined.
- Trial name
- FISTUCROHN (NCT03878498)
- Testing
- therapeutic management
- Where
- France
- Volunteers
- 212 people
- Sponsor
- Rennes University Hospital
Recto-vaginal Fistula
Stromal Vascular Fraction (SVF) for Treatment of Recto-vaginal Fistula
The purpose of this study is to determine safety of Stromal Vascular Fraction (SVF) for the treatment of recto-vaginal fistula.
- Trial name
- HULPCIR (NCT01548092)
- Testing
- Adipose-derived stem cells without expanded
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Fistula in Ano
High Type Fistula in Ano, Use Staged Seton, Loose Thick Sutures
Fistula in ano is a chronic problem for the patients. It causes distressing because of foul odor and soiling with recurrent infection and discharge.
- Trial name
- NCT05223309
- Testing
- Usinf thick loose sutures in seton techingues
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- Jabir Ibn Hayyan Medical University
Perianal Fistula
Diagnostic Value of Recto-perineal Ultrasound in Perianal Fistula
Perianal fistula is a common anal problem. It needs only surgery. MRI is the best preoperative diagnostic tool, but it is demanding as it is expensive, time consuming and needs an experienced radiologist.
- Trial name
- NCT06314945
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Zagazig University
Rectal Fistula
Anal Fistula Repair With Platelet-rich Plasma
Anal fistula is a very common disease with a high impact on life quality. The only commonly accepted treatment option is surgery.
- Trial name
- Aurora (NCT02678936)
- Testing
- PRP
- Where
- Switzerland
- Sponsor
- University Hospital, Basel, Switzerland
Anal Fistula
Clinical Trial to Evaluate the Efficacy and Safety of Stem Cells
Efficacy of treatment of perianal fistula with mesenchymal stem cells and surgery
- Trial name
- FISPAC (NCT01803347)
- Testing
- ◦Drug: ASCs. + fibrin glue, fibrin glue
- Where
- 5 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Fistula-in-ano
Collagen Paste vs Mucosal Advancement Flap for FIA
The treatment for fistula-in-ano (FIA) remains a challenge to General and Colorectal Surgeons Worldwide. A variety of surgical treatments have been described for high anal fistulas, but none offers the panacea of fistula…
- Trial name
- NCT06386835
- Testing
- Collagen Paste, Mucosal advancement
- Where
- 2 sites in Hong Kong
- Volunteers
- 118 people
- Sponsor
- Chinese University of Hong Kong
Anal Fistula
Anal Fistula Plug Versus Endorectal Advancement Flap
The purpose of this study is to determine whether anal fistula plug or endorectal advancement flap is more successful in the treatment of anal fistulas and compared both procedures with regards to cost.
- Trial name
- AFPERAF (NCT01931371)
- Testing
- Anal Fistula Plug, Endorectal Advancement Flap
- Where
- Switzerland
- Volunteers
- 71 people
- Sponsor
- University of Zurich
Anal Fistula, Rectal Fistula
A Prospective Evaluation of the Strattice-LIFT to Treat Anal Fistula
This clinical trial will evaluate the safety and efficacy of the Strattice-LIFT procedure to treat anal fistulas.
- Conditions
- Anal Fistula, Rectal Fistula, Fistula in Ano, Transsphincteric Fistula
- Trial name
- NCT02423330
- Testing
- Strattice-LIFT
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Rush University Medical Center
Rectal Fistula
Is the Use of Blood Platelets Effective in the Treatment of Difficult Fistulas Related to the Anal Sphincter?
Rationale: Closure of the internal opening is the most accepted standard procedure in the treatment of peri-anal fistulas. The mucosal advancement flap is considered as golden standard.
- Trial name
- NCT01615302
- Testing
- Mucosa advancement flap, Platelet rich plasma (PRP)
- Where
- 6 sites in Netherlands
- Volunteers
- 120 people
- Sponsor
- Maastricht University Medical Center