Clinical trials: First Responders
Post-Traumatic Stress Disorder
Online Therapy for Posttraumatic Stress Symptoms in WTC Responders and Survivors
If you worked or volunteered as a WTC rescue, recovery or clean-up worker after the 9/11 attacks, or are a survivor of the WTC 9/11 attacks, and you are still experiencing Posttraumatic Stress Disorder (PTSD) symptoms related to…
- Trial name
- NCT03154151
- Testing
- Online Cognitive-Behavioral Therapy, Online Supportive Therapy
- Where
- 4 sites in United States
- Volunteers
- 105 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Resilience, Stress
First Responder Resiliency Program During COVID-19
Evaluating a wellness program developed to provide effective sustainable solutions for medical professionals providing care to COVID-19 pandemic patients.
- Conditions
- Resilience, Stress, Sleep
- Trial name
- NCT04536376
- Testing
- Resilience Program
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Substance Use Disorders
Effects of In-Home Addiction Treatment for First Responders
Retrospective analysis to evaluate impact of an in-home addiction treatment program on first responders with substance use disorder.
- Trial name
- NCT03907709
- Testing
- In-Home Addiction Treatment Program
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- In-Home Addiction Treatment Institute, Inc.
PTSD
Transcendental Meditation in Veterans and First Responders With PTSD
The present study is part of a Phase 3 multi-site clinical trial that will recruit veterans and first responders diagnosed with PTSD, where they will be randomized to receive either Transcendental Meditation (TM) or Present…
- Trial name
- NCT05645042
- Testing
- Transcendental Meditation (TM), Present Centered Therapy (PCT)
- Where
- 5 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Lung Disease, Interstitial
Evaluation of Efficacy and Safety of Rituximab With Mycophenolate Mofetil in Patients With Interstitial Lung Diseases
The purpose of the study is to evaluate the efficacy on lung function 6 months after one course of rituximab (2 infusions) and mycophénolate mofétil (MMF) treatment compared to one course of placebo and 6 months of MMF treatment…
- Trial name
- EvER-ILD (NCT02990286)
- Testing
- Rituximab, Mycophenolate Mofetil
- Where
- 5 sites in France
- Volunteers
- 122 people
- Sponsor
- University Hospital, Tours
Cardiovascular Function in EMTs
Vascular Function and Oxidative Stress in Emergency Medical Responders
The goal of this clinical trial is to characterize blood vessel function and oxidative stress (a harmful condition that damages cells and tissues) in emergency medical technicians (EMTs).
- Trial name
- VF-EMT (NCT06985394)
- Testing
- Antioxidant cocktail
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Cardiovascular Diseases
Heartmatters Challenge - First Responders
The purpose of this protocol is to observe whether providing the first responder population with a multi-tiered therapeutic lifestyle modification program, including regular blood testing, diet and telephonic lifestyle coaching…
- Trial name
- HMC-FR (NCT03322046)
- Testing
- Lifestyle Program
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Boston Heart Diagnostics
Psilocybin, Psychotherapy, Group
Psychedelic-assisted Group Program for First Responders
This study is a two-group feasibility study of oral psilocybin combined with a 12-week group-based program, customized for firefighters.
- Trial name
- NCT06471959
- Testing
- Psilocybin
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Empower Research Inc
Stress, Parenting
Stress Physiology and Intervention Feasibility Among First Responder Parents
The specific aims of this study are to: 1. Demonstrate the usability and acceptability of a smart watch in parents to remotely monitor stress responses or symptoms in individuals participating in prevention or treatment…
- Trial name
- NCT05875246
- Testing
- Micro-interventions
- Where
- 2 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Erectile Dysfunction
Efficacy & Safety of a 2nd Series of Low Intensity Shock Waves for ED on Partial Responders to First Treatment
Low intensity shock waves (LISW) have been proven in animal studies to induce local growth of new blood vessels. The investigators hypothesized that LISW therapy could improve the symptoms of patients with erectile dysfunction…
- Trial name
- NCT01601262
- Testing
- Low Intensity Extracorporeal Shock waves (Cardiospec 1000)
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Rambam Health Care Campus
Traumatic Brain Injury and Co-occurring Disorders
Veteran's Interdisciplinary Care for Traumatic Brain Injury and Co-Occurring Disorders Rehabilitation Trial
The goal of this clinical trial is to learn if the Avalon Action Alliance Interdisciplinary Outpatient Rehabilitation Program (IORP) can reduce long-lasting symptoms of traumatic brain injury (TBI) and co-occurring disorders in…
- Trial name
- VICTORY-RCT (NCT07463027)
- Testing
- 3-week interdisciplinary outpatient rehab program (IORP)
- Where
- United States
- Volunteers
- 416 people
- Sponsor
- Medical College of Wisconsin
Holistic Care, Mental Health
Using Integrated Care and Wearable Technology to Evaluate Outcomes of the Shields & Stripes Program for Veterans and First Responders
This study aims to evaluate outcomes from the Shields \& Stripes (S\&S) program - a 12-week, multidisciplinary wellness intervention designed for veterans and first responders.
- Conditions
- Holistic Care, Mental Health, Sleep, PTSD
- Trial name
- S&S Wellness (NCT07452900)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Baylor University
Type 2 Diabetes
Phenotype Evaluation in Insulin Naive Patients Using Lantus (Insulin Glargine)
Primary objective: Efficacy assessment of the percentage of positive responders patients receiving Lantus plus glucophage association.
- Trial name
- GALATEE (NCT00653302)
- Testing
- Lantus (insulin glargine) + Glucophage (Metformin)
- Where
- France
- Volunteers
- 280 people
- Sponsor
- Sanofi
Mental Health, Stress Disorder, Post Traumatic
Psychological Stress and Support Needs of Volunteer First Responders After Smartphone-based Cardiac Arrest Alerts
Out-of-hospital cardiac arrest is a serious emergency. In many areas, trained volunteers are alerted by a smartphone app to help before emergency services arrive.
- Trial name
- BRAVE (NCT07607808)
- Testing
- Structured Debriefing
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Hospital, Aachen
Out-of-hospital Cardiac Arrest (OHCA), Agonal Breathing
CPR and Agonal Breathing Recognition Training for Police Officers
This study will evaluate an educational training program for police officers in New Taipei City, Taiwan. Police officers may arrive at out-of-hospital cardiac arrest events before emergency medical services and may be able to…
- Conditions
- Out-of-hospital Cardiac Arrest (OHCA), Agonal Breathing, Cardiopulmonary Resuscitation Training
- Trial name
- CPR-AB Police (NCT07695766)
- Testing
- CPR Refresher and Agonal Breathing Recognition Training
- Where
- Taiwan
- Volunteers
- 3,439 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Shift Workers' Health, Time Restricted Eating
The Healthy Heroes Study
This is the first study of its kind to assess and test an intervention to improve biological rhythms and general health of shift workers, specifically first responders with San Diego Fire and Rescue.
- Conditions
- Shift Workers' Health, Time Restricted Eating, Fasting
- Trial name
- NCT03533023
- Testing
- Time Restricted Eating + Standard of Care, Standard of Care
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Rheumatoid Arthritis (RA), Systemic Lupus Erythematosus (SLE)
COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders
This is a randomized, multi-site, adaptive, open-label clinical trial comparing the immune response to different additional doses of COVID-19 vaccine in participants with autoimmune disease requiring IS medications.
- Conditions
- Rheumatoid Arthritis (RA), Systemic Lupus Erythematosus (SLE), Pemphigus Vulgaris, Multiple Sclerosis (MS)
- Trial name
- NCT05000216
- Testing
- Moderna mRNA-1273, BNT162b2, Ad26.COV2.S
- Where
- 29 sites in United States
- Volunteers
- 258 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Heart Rate Monitoring
Vital Signs Monitoring of Emergency Responders in Different States
The goal of this observational study is to learn about emergency responder in different states. The main questions it aims to answer are: Ten vital signs and behavioral parameters in different states (quiet, after post, after…
- Trial name
- NCT06076057
- Testing
- vital signs monitoring
- Where
- China
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Alcohol Use Disorder (AUD), PTSD
PsiloStudy: Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)
This study is a phase 2 single-site, double-blind, placebo-controlled, randomized clinical trial with an open-label extension phase to examine the safety of psilocybin (25 mg) combined with psychological support (Psi-PS) for…
- Trial name
- Psi-PS (NCT06853912)
- Testing
- Psilocybin 25 mg
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Nathan Brashares Sackett
Out-Of-Hospital Cardiac Arrest
Enhanced Community First Responder System Evaluation in Singapore
The rise in out-of-hospital cardiac arrest (OHCA) cases in Singapore highlights the need for effective bystander cardiopulmonary resuscitation (BCPR).
- Trial name
- TCPR-Link (NCT06530433)
- Testing
- CPRCard + TCPR Link App and Web, CPRCard Only
- Where
- Singapore
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital