Clinical trials: Firefighters
Posttraumatic Stress Disorder
Study Comparing Three Doses of MDMA Along With Therapy in Veterans With Posttraumatic Stress Disorder
The goal of this clinical trial is to learn if MDMA-assisted therapy is safe and effective and reducing PTSD symptoms in veterans with chronic PTSD.
- Trial name
- NCT01211405
- Testing
- Low dose MDMA-assisted therapy, Medium dose MDMA-assisted therapy, Full dose MDMA-assisted therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Resilient Pharmaceuticals
Firefighters' Mental Health
F.I.R.E.- Fighters With Focus, Intention, Regulation and Engagement
Firefighters are routinely exposed to potentially traumatic events, making them vulnerable to debilitating mental health problems.
- Trial name
- NCT07484711
- Testing
- FIRE
- Where
- Portugal
- Volunteers
- 53 people
- Sponsor
- University of Coimbra
Cancer Prevention
Firefighters Preventing Cancer Online Training Program
The goal of this two-arm, Cluster Randomized Trial is to evaluate an e-health training program for volunteer firefighters to reduce their risk of exposures to carcinogens and to increase their understanding and intentions of…
- Trial name
- NCT05745246
- Testing
- e-health training program
- Where
- Canada
- Volunteers
- 179 people
- Sponsor
- IWK Health Centre
Vascular Function, Atherothrombosis
Effect of Fire Suppression and Emergency Duties on Vascular Function
Firefighters are at increased risk of death from heart attacks when compared to other emergencyy service professionals whose jobs involve similar components such as emergency call-outs and shift work.
- Trial name
- NCT01805063
- Testing
- Forearm Vascular Study, Badimon Chamber
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
PTSD
Attention Control Training for the Prevention of PTSD in Firefighters
The study aimed to examine the effect of Attention Control Training (ACT) intervention on reducing PTSD symptoms in firefighters.
- Trial name
- NCT05754164
- Testing
- Attention Control Training
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Adai Technology (Beijing) Co., Ltd.
Vascular Function, Atherothrombosis
Comparison of Vascular Function in Emergency Service Professionals
Emergency Service Professionals have an increased risk of death from heart attacks when compared to the general public. All the emergency professions share similar responsibilities such as emergency call-outs and shift work.
- Trial name
- FIRECOP (NCT01813032)
- Testing
- Forearm Vascular Study, Badimon Chamber
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Tinnitus
Cognitive Training for Firefighters With Tinnitus
The purpose of this research study is to determine whether the Brain Fitness Program-Tinnitus affects how tinnitus is perceived and if its use aids in the recovery of cognitive functions that may be affected by tinnitus.
- Trial name
- FEMAICT (NCT01458821)
- Testing
- Brain Fitness Program - Tinnitus
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Lung Injury, Particulate Matter Inhalation Injury
Food Intake REstriction for Health OUtcome Support and Education (FIREHOUSE) Trial
This is a randomized-controlled unblinded clinical trial to investigate dietary intervention on metabolic biomarker assessment in World Trade Center (WTC) Lung Injury (LI) in firefighters.
- Trial name
- NCT03581006
- Testing
- Low-Calorie Mediterranean Diet, Technology based monitoring and behavioral participation, Usual care group
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Healthy
Occupational Exposure of Firefighters to Environmental Pollutants
The aim of the current trial is to assess the exposure of firefighters (FF) to environmental pollutants emitted from fires, to explore the association of exposure with their health status and to compare these data with those of…
- Trial name
- NCT05256212
- Testing
- exposure to environmental contaminants
- Where
- Israel
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Stress, Sympathetic Nervous System
Glucose Levels as a Biomarker for Stress in Firefighters
Stress is known to cause physical structures in the brain to dysregulate, resulting in health problems like cancer, cardiac disease, metabolic disorders (obesity), and depression.
- Conditions
- Stress, Sympathetic Nervous System, Hypothalamic Pituitary Adrenal
- Trial name
- NCT06899373
- Testing
- Continuous glucometer
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Utah
Anosmia, Chronic Obstructive Pulmonary Disease
Firefighter's Longitudinal Airway and Respiratory Exposome/Multiome Study (FLARES)
Background: Exposure to smoke increases the risk of many diseases. People can be exposed to dangerous levels of smoke during wildfires. Also, smoke from fires that burn manmade materials may contain toxic chemicals.
- Conditions
- Anosmia, Chronic Obstructive Pulmonary Disease, Hyposmia, Chronic Rhinosinusitis
- Trial name
- NCT07867184
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cancer Prevention, Firefighters
Behavior and Risk Awareness Through Video Education for Firefighters
The goal of this clinical trial is to evaluate the impact of short documentary-style videos to educate and inspire firefighters to take safety measures to prevent cancer incidence and mortality.
- Trial name
- BRAVE (NCT07494617)
- Testing
- Video 1, Video 2, Video 3
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Physical Performance Parameters, Exercise Recovery
Effects of Beef-Forward Ready-to-Eat Meals on Recovery Following Simulated Fire Suppression Activities
This clinical trial aims to determine whether consuming beef-based protein before and after physically demanding simulated firefighting activities improves recovery, physical performance, and cognitive performance in healthy…
- Conditions
- Physical Performance Parameters, Exercise Recovery, Cognition, Muscle Damage
- Trial name
- FIRE-BEEF (NCT07822048)
- Testing
- Beef-Based Protein Ready-to-Eat Meals, Plant-Based Protein Ready-to-Eat Meals
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sam Houston State University
Heat Stress Disorders
Enhanced Firefighter Rehab Trial: The Role of Aspirin in Preventing Heat Stress Induced Platelet Activation
The purpose of this study is to determine if aspirin taken by firefighters prevents platelets from becoming sticky when body temperature rises during work in protective clothing.
- Trial name
- EFFoRT (NCT01066923)
- Testing
- Daily aspirin (ASA), Active cooling, Acute aspirin (ASA)
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Dave Hostler
Coronary Disease
Long Term Efficacy and Safety of Firebird Sirolimus-Eluting Stent In Complex Coronary Lesions
The purpose of this study is to investigate the long term efficacy and safety of firebird sirolimus-eluting stent for treatment of complex coronary Lesions.
- Trial name
- FIREMAN (NCT00552656)
- Testing
- Firebird(TM) Sirolimus-Eluting Stent
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xijing Hospital
Health Adult Subjects, Exposure Occupational
French Military Firefighters to Assess Relationships Between Exposome and Health.
The aim of the study is to describe professional exposures and health events among French military firefighters (both active-duty personnel and veterans) and identify potential relationships between the exposome (the total…
- Conditions
- Health Adult Subjects, Exposure Occupational, Health Behavior, Risky, Occupational Health
- Trial name
- COMITEX-BSPP (NCT07270627)
- Where
- France
- Volunteers
- 1,811 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Adults, Firefighters
Cranial Electrotherapy Stimulation: Piloting a Road to PTSD Prevention in First Responders
The goal of this study is to test whether active duty firefighters find it possible and suitable to do cranial electrotherapy stimulation (CES) at home, and test whether CES influences measures of depression and posttraumatic…
- Trial name
- NCT06203717
- Testing
- Alpha-Stim AID cranial electrotherapy stimulation
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Vascular Function, Atherothrombosis
Effect of Real-fire Training on Vascular Function
Fire-fighters are at increased risk of death from heart attacks when compared to other emergency service professionals whose jobs involve similar components such as emergency call-outs and shift work.
- Trial name
- FIREPROOF (NCT01812317)
- Testing
- Forearm Vascular Study, Badimon Chamber Study
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Cancer
Occupational Exposures Among Firefighters
This study aims to understand the effect of occupational exposures, including PFAS exposures, among firefighters.
- Trial name
- NCT06173843
- Testing
- PFAS / heavy metal testing, exposures
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Vincere Cancer Center
Clonal Hematopoiesis of Indeterminate Potential, Monoclonal Gammopathy
Pre-malignant States to Hematologic Malignancies in Firefighters
The purpose of the study is to evaluate if firefighter exposure to hazardous compounds will increase the incidence of premalignant hematological states which subsequently increases the risk of the development of hematologic…
- Conditions
- Clonal Hematopoiesis of Indeterminate Potential, Monoclonal Gammopathy, Non Hodgkin Lymphoma, Leukemia
- Trial name
- NCT06870760
- Testing
- Monoclonal Gammopathy, Complete Blood Count with differential (CBC w/ diff), Clonal hematopoiesis (CHIP)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences