Clinical trials: Fibromyalgia (FM)
Fibromyalgia (FM), Quantitative Sensory Testing
Investigation of Pain Modulation Phenotypes in Female Patients With Fibromyalgia
Fibromyalgia is characterized by altered pain processing, including impaired descending pain inhibition and central sensitization.
- Conditions
- Fibromyalgia (FM), Quantitative Sensory Testing, Central Sensitization, PRESSURE PAIN THRESHOLD
- Trial name
- NCT07640607
- Testing
- Quantitative Sensory Tests(QST) protocol, Clinical Scales
- Volunteers
- 82 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Fibromyalgia (FM), Vitamin B 12 Deficiency
Pre- and Post-Treatment Investigation of B12 and Folic Acid (Folate) Levels in Patients Receiving Antiepileptic (Anticonvulsant) Treatment for Fibromyalgia: Retrospective Study
Fibromyalgia is a rheumatological disorder characterised by chronic widespread body pain, second most common after osteoarthritis. The overall prevalence is 2-8% and it is more common in women.
- Conditions
- Fibromyalgia (FM), Vitamin B 12 Deficiency, Folic Acid Deficiency
- Trial name
- NCT07013305
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Fibromyalgia
Effect of an Amino-Acid-Based Blend on Human Growth Hormone (hGH) and Fibromyalgia (FM) Symptoms
The purpose of the study is to investigate the effect of the amino acid-based blend on growth hormone levels (measured by IGF-1) and clinical symptoms in individuals with treatment-resistant FM and low-normal hGH.
- Trial name
- NCT04510181
- Testing
- amino acid-based blend
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Pekarovics, Susan, MD
Fibromyalgia (FM)
Silymarin vs Hesperidin/Diosmin in Fibromyalgia
Fibromyalgia is a chronic disease, characterized by chronic widespread pain, physical exhaustion, sleep problems, and unexplained pain in both joints and muscles.
- Trial name
- SHD-FM (NCT07293767)
- Testing
- Silymarin (LEGALON), Diosmin / Hesperidin (Daflon), no intervention (control group)
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Fibromyalgia (FM), Alexithymia
Alexithymia Levels in Fibromyalgia
The primary aim of this study was to investigate the changes in alexithymia levels in fibromyalgia patients over a six-month period following a combined treatment and to assess the relationship between changes in fibromyalgia…
- Trial name
- NCT06841302
- Testing
- Fibromyalgia Agents
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Fibromyalgia
A Phase 3 Study to Evaluate the Efficacy and Safety of TNX-102 SL Taken Daily in Patients With Fibromyalgia
This is a Phase 3, randomized, parallel-group, double-blind, placebo-controlled, 14-week study designed to evaluate the efficacy and safety of TNX-102 SL 5.6 mg (2 x 2.8 mg tablets) taken daily at bedtime for the treatment of…
- Trial name
- RESILIENT (NCT05273749)
- Testing
- TNX-102 SL Tablet, 5.6 mg
- Where
- 33 sites in United States
- Volunteers
- 457 people
- Sponsor
- Tonix Pharmaceuticals, Inc.
Fibromyalgia (FM)
Investigating the Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on the Brain in People With Fibromyalgia
The first goal of this study is to see how brain activity changes in people with fibromyalgia after they get a treatment called rTMS (repetitive transcranial magnetic stimulation).
- Trial name
- rTMS (NCT07260864)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Rochester
Fibromyalgia (FM), tDCS
Home-based Transcranial Direct Current Stimulation (tDCS) Compared to Duloxetine: Non-inferiority Clinical Trial (FIBROSTIM)
Fibromyalgia is characterized by widespread pain, fatigue, non-restorative sleep, and psychocognitive alterations, compromising quality of life and leading to absenteeism and early retirement.
- Conditions
- Fibromyalgia (FM), tDCS, Duloxetine, BDNF
- Trial name
- FIBROSTIM (NCT07203339)
- Testing
- Duloxetine (60 mg) once daily, Home-based transcranial direct current stimulation, Duloxetine 60 mg
- Where
- Brazil
- Volunteers
- 610 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Fibromyalgia
Transcutaneous Electrical Nerve Stimulation (TENS) and Fibromyalgia (FM)
Fibromyalgia as a clinical syndrome is defined by chronic widespread muscular pain, fatigue and tenderness with hyperalgesia to pressure over tender points.
- Trial name
- TENS&FM (NCT00932360)
- Testing
- TENS
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Dana Dailey
Fibromyalgia, Interstitial Cystitis
HBOT for Patients With IC/FM (Interstitial Cystitis/Fibromyalgia)
The investigators observed 12 fibromyalgia and interstitial cystitis patients undergoing hyperbaric oxygen oxygen treatment in a multiplace pressure chamber for 90 minutes, 40 treatment each, using an oro-nasal mask.
- Trial name
- IC/FMHBOT (NCT03693001)
- Testing
- Intermittent Exposure to Oxygen via Oro-Nasal Mask
- Volunteers
- 12 people
- Sponsor
- University of South Florida
Fibromyalgia
Predictive Models on Pain and Severity in FM Patients
The primary goal of this research project is to develop different prediction models in fibromyalgia disease through the application of machine learning techniques and to assess the explainability of the results.
- Trial name
- NCT04918602
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- University of Castilla-La Mancha
Fibromyalgia (FM)
Feasibility and Effects of Noninvasive Brain Stimulation on Pain Perception in People With Fibromyalgia
The goal of this interventional study is to learn whether noninvasive brain stimulation (NIBS) will have an effect on pain perception in people with fibromyalgia.
- Trial name
- NCT07644221
- Testing
- Primary Motor Cortex Stimulation, Occipital Lobe Stimulation
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Pulkit Grover
Irritable Bowel Syndrome (IBS), Fibromyalgia (FM)
Evaluating the Added Benefit of Osteopathic Care to a Flexi-FODMAP Diet in Fibromyalgia Patients With Irritable Bowel Syndrome
Dietary modifications are often recommended as first-line treatment for irritable bowel syndrome, with the FODMAP diet being the most effective intervention to improve global gastrointestinal symptoms.
- Trial name
- POISE-IBS-RCT (NCT07176078)
- Testing
- Osteopathic care, Flexi-FODMAP Diet
- Where
- Belgium
- Volunteers
- 96 people
- Sponsor
- Universitair Ziekenhuis Brussel
Fibromyalgia
Acute Effects of Exercise in Women With Fibromyalgia (FM)
The investigators previous studies of aerobic exercise in women with fibromyalgia (FM) have shown that exercise improves body functions and/or symptom severity in most patients, but not in all.
- Trial name
- NCT01592916
- Where
- Sweden
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Fybromyalgia, Fibromyalgia (FM)
Interventional Study on the Effects of Forest Therapy in Fibromyalgia Patients
The goal of this clinical trial is to evaluate if Forest therapy can reduce pain levels and improve the quality of life related to the level of pain perceived in fibromyalgia patients.
- Trial name
- ForCare (NCT07648563)
- Testing
- Forest therapy
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Azienda USL Toscana Nord Ovest
Fibromyalgia (FM)
Personalized Ultrasonic Brain Stimulation for Fibromyalgia
The primary purpose of this research is to evaluate a new kind of noninvasive brain stimulation intervention using the investigational ultrasound device, which might be useful for treating fibromyalgia.
- Trial name
- BEAMforFMS (NCT07361328)
- Testing
- Low-intensity ultrasound brain stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Utah
Fibromyalgia (FM) OR Fibromyalgia Syndrome
Effects of Reiki Therapy in Women With Fibromyalgia
The goal of this randomized clinical trial is to evaluate the effects of a 4-week Reiki therapy program in women with fibromyalgia.
- Trial name
- NCT07821034
- Testing
- Reiki Intervention
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Fibromyalgia (FM)
Probiotics for Cognitive Function, Pain, and Quality of Life in People With Fibromyalgia
Fibromyalgia is a complex chronic disorder in which emerging evidence suggests a relevant role of the gut microbiota in modulating physiological processes through the gut-brain axis.
- Trial name
- NCT07582965
- Testing
- Multispecies Probiotic (Teoliance HPi10)
- Where
- Spain
- Volunteers
- 97 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Fibromyalgia (FM)
Effects of Immersive Virtual Reality in Fibromyalgia
Fibromyalgia is considered a disease of unknown etiology, which It affects between 2 to 5% of the population in developed countries, mostly women, diagnosed mainly between 40 and 50 years of age, and whose main characteristic is…
- Trial name
- NCT06658223
- Testing
- Exercise with virtual reality
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Universidad San Sebastián
TMD/Orofacial Pain, Fibromyalgia (FM)
Diagnostic and Prognostic Salivary Biomarkers in Chronic Muscle Pain
A large proportion of the adult population worldwide currently lives with chronic muscle pain, with more than half of those affected experiencing pain localized to the face and jaw.
- Trial name
- NCT06994156
- Where
- Sweden
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet