Clinical trials: Fibromyalgia, open to volunteers
Fibromyalgia (FM) OR Fibromyalgia Syndrome, Manuel Therapy
Effects of Adding Vagal Neuromodulation to Manual Therapy in Women With Fibromyalgia
The aim of this study is to investigate the effect of transcutaneous auricular vagus nerve stimulation (taVNS) added to manual therapy on pain, autonomic nervous system function, and illness perception in female patients…
- Conditions
- Fibromyalgia (FM) OR Fibromyalgia Syndrome, Manuel Therapy, Chronic Widespread Pain, Autonomic Nervous System Dysfunction
- Trial name
- NCT07894588
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Manual Therapy Program, Diaphragmatic Breathing and Stretching Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Hasan Kalyoncu University
Arthritis, Fibromyalgia
Wearable Biofeedback Devices for Remote Physiotherapy and Rehabilitation
This study evaluates the effectiveness of wearable biofeedback devices in improving pain, mobility, and rehabilitation outcomes in elderly patients with arthritis and fibromyalgia in Karachi, Pakistan.
- Conditions
- Arthritis, Fibromyalgia, Chronic Pain
- Trial name
- NCT06960330
- Testing
- Wearable Biofeedback + Virtual Physiotherapy, Standard Physiotherapy Exercises
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- University of Karachi
Myofacial Pain, Myofacial Pain Syndrome
Evaluation of the Effect of Adding Sodium Bicarbonate to Lidocaine in the Treatment of Myofascial Pain Syndrome
This study is designed to evaluate a method to improve the treatment of myofascial pain syndrome (MPS), a common condition that causes muscle pain, tenderness, and reduced movement due to the presence of trigger points in…
- Conditions
- Myofacial Pain, Myofacial Pain Syndrome, Myofacial Pain Syndromes, Trigger Point Pain, Myofascial
- Trial name
- BIC-LIDO-MPS (NCT07572994)
- Testing
- Lidocaine 2 %, Lidocaine + Sodium Bicarbonate
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Fibromyalgia (FM)
Feasibility and Effects of Noninvasive Brain Stimulation on Pain Perception in People With Fibromyalgia
The goal of this interventional study is to learn whether noninvasive brain stimulation (NIBS) will have an effect on pain perception in people with fibromyalgia.
- Trial name
- NCT07644221
- Testing
- Primary Motor Cortex Stimulation, Occipital Lobe Stimulation
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Pulkit Grover
Juvenile Idiopathic Arthritis (JIA), Fibromyalgia
Biopsychosocial Risk Influences on the Development and Generation of Early-Onset Chronic Pain
The purpose of the study is to discover the underlying subtypes of chronic musculoskeletal pain (muscle and joint pain) in youth.
- Conditions
- Juvenile Idiopathic Arthritis (JIA), Fibromyalgia, Lupus, Scoliosis
- Trial name
- BRIDGE Pain (NCT07602595)
- Testing
- Not applicable- observational study
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Fibromyalgia, Interoception
The Role of Interoceptive Sensitivity in Central Sensitization Symptom Severity in Fibromyalgia
In fibromyalgia, the increased central sensitization symptom burden can lead to a disruption in the individual's interoception and difficulties in managing symptoms.
- Conditions
- Fibromyalgia, Interoception, Central Sensitization
- Trial name
- NCT07878286
- Testing
- Central Sensitization Inventory, The Multidimensional Assessment of Interoceptive Awareness scale-2, Revised Fibromyalgia Impact Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
ME/CFS, Fibromyalgia (FM)
Whole-body Cryotherapy in Those With Chronic Fatigue: A Feasibility Study
Chronic fatiguing illnesses such as Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Fibromyalgia, and Long COVID are becoming a major global health challenge.
- Conditions
- ME/CFS, Fibromyalgia (FM), Long-COVID, Control Group
- Trial name
- NCT07874217
- Testing
- Cryotherapy
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Fibromyalgia
Open-Label Safety Study of AXS-14 in Subjects With Fibromyalgia
This is a Phase 3, multi-center, 52-week, open-label trial to evaluate the long-term safety and efficacy of AXS-14 in the management of fibromyalgia.
- Trial name
- NCT07637162
- Testing
- AXS-14 (esreboxetine)
- Where
- 35 sites in United States
- Volunteers
- 300 people
- Sponsor
- Axsome Therapeutics, Inc.
Fibromyalgia, Fibromyalgia (FM)
Feasibility and Preliminary Effects of an Asynchronous Microlearning Intervention on Fibromyalgia Knowledge Among Primary Health Care Workers
This randomized controlled pilot trial will evaluate the feasibility and preliminary effects of an asynchronous microlearning intervention on fibromyalgia knowledge among Primary Health Care workers.
- Conditions
- Fibromyalgia, Fibromyalgia (FM), Fibromyalgia Syndrome
- Trial name
- FIBROK-PILOT (NCT07865767)
- Testing
- Written Educational Material on Fibromyalgia, Asynchronous Microlearning Intervention on Fibromyalgia
- Where
- Chile
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Instituto Neurociencia Del Dolor
Fibromyalgia, Fibromyalgia (FM)
Multisite Transcutaneous Electrical Nerve Stimulation in Fibromyalgia: A Randomized, Double-Blind, Sham-Controlled Crossover Trial Comparing Two Stimulation Modalities
Fibromyalgia is a chronic and multifactorial disorder characterized by widespread musculoskeletal pain, heightened pain sensitivity, fatigue, sleep disturbances, cognitive complaints, and affective symptoms such as anxiety and…
- Conditions
- Fibromyalgia, Fibromyalgia (FM), Fibromyalgia (FM) OR Fibromyalgia Syndrome
- Trial name
- FIBROPULSE (NCT07872631)
- Testing
- EXOPULSE Mollii Suit
- Volunteers
- 24 people
- Sponsor
- Institut De La Colonne Vertebrale Et Des Neurosciences
Fibromyalgia
Psychologically Informed Telerehabilitation for Fibromyalgia
Fibromyalgia is a long-term condition that can cause widespread pain, fatigue, sleep problems, difficulties with concentration, and limitations in daily activities.
- Trial name
- FibroPIPT (NCT07865403)
- Testing
- Online Psychologically-Informed Physical Therapy, Paper-based booklet
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- IRCCS San Raffaele Roma
Fibromyalgia
Melatonin and Immunonutrition for Pain Relief in Fibromyalgia
Fibromyalgia (FMS) is characterized by chronic musculoskeletal pain, sleep disturbances, and fatigue. It is not entirely clear how Bcomplex vitamins affect the human pain system, while at the same time there have been approaches…
- Trial name
- NCT07863232
- Testing
- Melatonin 1mg and intravenous B-complex vitamin drip
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Thessaly
Fibromyalgia
Self-regulation of Real-time fMRI Brain Activity in Chronic Pain
This study aims to explore the usefulness of self-regulation of brain activity in patients with fibromyalgia. Patients will use real-time functional magnetic resonance imaging (fMRI) neurofeedback to observe and regulate their…
- Trial name
- NCT07023523
- Testing
- Cognitive Behavioral Therapy, Disease Education
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Brigham and Women's Hospital
Mitochondrial Diseases, Myalgic Encephalomyelitis Chronic Fatigue Syndrome
The Precision Mito- Mito Map COMPASS Study
Mito Map is a research tool that produces an Energy Score from information provided by a participant. This remote observational study has an initial enrollment target of 400 adults across seven prespecified cohorts: healthy…
- Conditions
- Mitochondrial Diseases, Myalgic Encephalomyelitis Chronic Fatigue Syndrome, Post-COVID-19 Condition, Postural Orthostatic Tachycardia Syndrome
- Trial name
- COMPASS (NCT07856121)
- Testing
- Mito Map Energy Score and Home Functional Assessments
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- AI Agent Vault, Inc. d/b/a Precision Mito
Fibromyalgia Syndrome
Effects of Basic Body Awareness Therapy Added to Aerobic Exercise in Women With Fibromyalgia
This study aims to investigate the effects of Basic Body Awareness Therapy combined with aerobic exercise on inflammatory biomarkers (interleukin-6 and cortisol), cognitive functions, and depression levels in women diagnosed with…
- Trial name
- BBAT-FMS (NCT07851896)
- Testing
- Basic Body Awareness Therapy, Moderate-Intensity Aerobic Exercise
- Volunteers
- 40 people
- Sponsor
- Hacer Önen Tekin
Hyperthermia, Chronic Primary Pain
Hyperthermia in Patients With Chronic Primary Pain - Effects on Thermoregulation, Somatosensory System and Movement Evoked Pain
This study, in a quasi-experimental matched two-group pre-post design, investigates the effect of serial water-filtered whole-body hyperthermia on circadian core body temperature, the somatosensory system (nociception) and the…
- Conditions
- Hyperthermia, Chronic Primary Pain, Widespread Pain, Muscular Disease
- Trial name
- HYPPRI-1 (NCT07101978)
- Testing
- serial whole body hyperthermia
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Fibromyalgia (FM)
Dietary Strategies for the Treatment of Fibromyalgia in Overweight and Obese Patients
Spontaneous, non-sponsored, interventional, controlled, randomized, parallel-arm clinical study. Primary objective To assess the impact of specific dietary approaches (ketogenic diet, Mediterranean diet, or Mediterranean diet…
- Trial name
- FIBRODIET (NCT07517757)
- Testing
- Very Low-Calorie Ketogenic Diet, Mediterranean diet, Mediterranean diet enriched by GABA-producing probiotic
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Universita degli Studi di Genova
Chronic Pain, Chronic Pain Syndrome
Shiatsu for Chronic Non-Inflammatory Pain in Children and Adolescents
The goal of this clinical trial is to learn if adding Shiatsu therapy to standard treatment can improve quality of life in children and adolescents with chronic pain that is not caused by inflammation.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain and Comorbid Emotional Problems, Chronic Pain, Psychogenic
- Trial name
- ShiQoL (NCT06929598)
- Testing
- Shiatsu Therapy
- Where
- 2 sites in Israel
- Volunteers
- 40 people
- Sponsor
- Tel Aviv University
Fibromyalgia (FM), Posttraumatic Stress Disorder (PTSD)
Treatment of Fibromyalgia and PTSD With Live and Inactive Vagus Nerve Stimulation With PEPC
Fibromyalgia (FM) pain and PTSD are highly prevalent and comorbid with associated increased risk of negative physical and mental health outcomes, including higher risk for opioid use and suicide.
- Trial name
- SWIFT-RELIEVE (NCT07718984)
- Testing
- tAN plus PEPC
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- VA Office of Research and Development
Fibromyalgia
The Role of Pain Catastrophizing, Resilience, and Illness Perception in Predicting Fibromyalgia Impact in Patients With Fibromyalgia
This study aims to reveal the effects of pain catastrophizing, psychological resilience, and illness perception on the impact level of fibromyalgia in patients with fibromyalgia, to determine the predictive power of these…
- Trial name
- NCT07846501
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bilecik Seyh Edebali Universitesi