Clinical trials: Fibroids
Uterine Fibroids, D-chiro-inositol
Vitamin D, Epigallocatechin Gallate, D-chiro-inositol and Vitamin B6 in Uterine Fibroid
The study will evaluate the impact on uterine fibroids' volume of a combination of natural molecules including Epigallocatechin gallate, Vitamin D, D-chiro-inositol and Vitamin B6.
- Conditions
- Uterine Fibroids, D-chiro-inositol, Inositol, Epigallocatechin Gallate
- Trial name
- NCT05448365
- Testing
- Epigallocatechin gallate, Vitamin D, Vitamin B6, D-chiro-inositol
- Where
- 2 sites in Italy
- Volunteers
- 60 people
- Sponsor
- Lo.Li.Pharma s.r.l
Stress, Job, PTSD
The Sequestration of Holistic Stress Management Techniques for Adults
This remote study is intended to assist the population with access to cost-effective pastoral counseling for stress management in the workplace and every day life.
- Conditions
- Stress, Job, PTSD, Hypervigilance, Hyperthyroidism
- Trial name
- NCT06098755
- Testing
- Holistic Medicine (HM)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Goddess Zena I. Jones
Uterine Fibroids - 1St Diagnosis, Uterine Fibroids Affecting Pregnancy
Holistic Medicine Treatment of Uterine Fibroids-Adults
This clinical trial aims to evaluate the efficacy of holistic medicine treatments for unmarried women ("Bachelorettes") residing on U.S.
- Conditions
- Uterine Fibroids - 1St Diagnosis, Uterine Fibroids Affecting Pregnancy, Uterine Fibroid Degenerated
- Trial name
- HMTXUFAdult (NCT07219381)
- Testing
- Holistic Medicine (HM)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Virtual Tribunal Monastery
Uterine Fibroids (UF)
Ultrasound-Guided Stellate Ganglion Block Plus Propofol for Perimenopausal Insomnia With Anxiety
Laparoscopic myomectomy is a commonly performed minimally invasive gynecologic procedure. However, surgical trauma, tracheal intubation, and pneumoperitoneum may induce pronounced perioperative stress responses, resulting in…
- Trial name
- SGB-PROP-PIA (NCT07384468)
- Testing
- Ultrasound-Guided Stellate Ganglion Block
- Where
- China
- Volunteers
- 233 people
- Sponsor
- Xiaochen Ji
Heavy Menstrual Bleeding, Uterine Fibroids
Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids
The goal of this clinical trial is to determine the benefit of relugolix 40 milligrams (mg) once a day compared with placebo in heavy menstrual bleeding associated with uterine fibroids.
- Trial name
- NCT06671548
- Testing
- Relugolix
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Myomectomy, Fibroid Uterus
Risk of Hysterectomy at Time of Myomectomy
Uterine fibroids are the commonest tumor affecting the female reproductive tract and many instances they are asymptomatic but in some women there does appear to be an association with heavy menstrual blood loss and possibly…
- Conditions
- Myomectomy, Fibroid Uterus, Hysterectomy
- Trial name
- NCT07365969
- Where
- Egypt
- Volunteers
- 293 people
- Sponsor
- Ain Shams University
Uterine Fibroid, Pregnancy Complications
Pregnancy Outcomes Following Myomectomy
The most prevalent genital pathology, uterine fibroids have a detrimental impact on the health of women. Fibroid symptoms are typically more impactful on females and frequently require uterine excision.
- Conditions
- Uterine Fibroid, Pregnancy Complications, Reproductive Issues, Reproductive Sterility
- Trial name
- NCT06474065
- Testing
- Myomectomy
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centro di Ricerca Clinica Salentino
Fibroid Uterus
The Effects of One-time Intraoperative Methadone During Laparoscopic Hysterectomy in Reducing Opioid Prescription.
Currently, there is a nationwide epidemic of opioid abuse and overdose deaths. One source of excess opioids is overprescribing in the postoperative period.
- Trial name
- NCT06536517
- Testing
- Methadone
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
Fibroid Uterus, Pain, Postoperative
Pre-incisional Wound INfiltration and Hypogastric PLEXus Block Using Ropivacaine in Laparoscopic Myomectomy
The purpose of this study is to assess an impact of laparoscopic superior hypogastric plexus (SHP) block combined with preemptive troacar site infiltration on postoperative pain intensity following laparoscopic myomectomy.
- Trial name
- WINPLEX (NCT06429163)
- Testing
- Troacar site infiltration, Superior hypogastric plexus block
- Where
- Russia
- Volunteers
- 207 people
- Sponsor
- Saint Petersburg State University, Russia
Uterine Fibroid
Life Study: Lifestyle Intervention in Fibroid Elimination
The study will evaluate a lifestyle, nutrition, and exercise program to assess whether this program is acceptable and feasible for patients..Researchers will examine if the LIFE program can modify fibroid recurrence.
- Trial name
- NCT05416424
- Testing
- LIFE program
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Uterine Fibroids, Adenomyosis
Effect of Addition of Steroids on Duration of Analgesia
The purpose of the study is to investigate the differences in post-procedural pain scores and narcotic use among patients who receive a Superior Hypogastric Nerve Block (SHNB) with and without corticosteroid performed as part of…
- Trial name
- NCT04126824
- Testing
- Triamcinolone, Bupivacaine, Iohexol contrast
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Uterine Bleeding, Uterine Neoplasms
Anterior Quadratus Lumborum Block as a Component of Multimodal Analgesia for Abdominal Hysterectomies
The main goal of this randomised double-blinded controlled trial is to assess whether adding anterior quadratus lumborum block preoperatively can reduce intraoperative and postoperative opioid consumption, reduce pain after…
- Conditions
- Uterine Bleeding, Uterine Neoplasms, Uterine Diseases, Uterine Fibroids
- Trial name
- NCT07046949
- Testing
- ANTERİOR QUADRATUS LUMBORUM BLOCK, Parenteral administration of analgesics, General Anesthesia (GA)
- Where
- Ukraine
- Volunteers
- 56 people
- Sponsor
- Yuri Semenyuk Rivne Regional Clinical Hospital
Fibroid, Leiomyoma
Role of Senescent Cells in Uterine Fibroid Pathogenesis (SOUL Study)
The investigators are evaluating the role of senescent cells in uterine fibroids.
- Trial name
- SOUL (NCT06135870)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Johns Hopkins University
Uterine Fibroids, Hysteroscopic Myomectomy
Preoperative Administration of EGCG, Vitamin D and DCI Prior Hysteroscopic Myomectomy
The administration of Epigallocatechin gallate (EGCG), Vitamin D and D-Chiro-Inositol (DCI) are effective in reducing the volume of fibroids and improving the symptoms of uterine fibroids.
- Conditions
- Uterine Fibroids, Hysteroscopic Myomectomy, Treatment Compliance, Patient Compliance
- Trial name
- PREHYSMYOM (NCT06768086)
- Testing
- Hysteroscopic myomectomy
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centro di Ricerca Clinica Salentino
Uterine Fibroids (MeSH Heading: Leiomyoma)
A Clinical Study of KLH-2109 in Uterine Fibroids Patient With Menorrhagia and Pain
Multi-center, randomized, double-blind, parallel-group study to confirm superiority of KLH-2109 to placebo in uterine fibroids patient with menorrhagia and pain
- Trial name
- NCT05445167
- Testing
- KLH-2109
- Where
- Japan
- Volunteers
- 89 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Uterine Fibroids (UF)
Artificial Intelligence for the Intra-procedural Assessment of Uterine Artery Embolization
Uterine artery embolization is a minimally invasive treatment for symptomatic uterine fibroids, but intra-procedural assessment of embolization adequacy currently relies on subjective angiographic criteria.
- Trial name
- AI-EMBO (NCT07230444)
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Emanuele Barabino
Uterine Fibroids (Leiomyoma), Symptomatic Uterine Leiomyoma
Efficacy of Ultrasound Guided Microwave Ablation in the Treatment of Uterine Fibroids.
Uterine fibroids are the most common benign tumors of the female genital tract and can significantly affect the quality of life in reproductive-age women, causing symptoms such as heavy menstrual bleeding, pelvic pressure…
- Trial name
- MWAUF (NCT07235787)
- Testing
- Ultrasound-Guided Percutaneous Microwave Thermal Ablation
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Jihad Hussien Mohamed Mahmoud
Fibroid Uterus
Utility of Liposomal Bupivacaine Transversus Abdominal Plane Block for Open Myomectomy
The study team will be randomizing patients presenting for open myomectomy to either received transversus abdominal plane blocks with either liposomal bupivacaine or standard bupivacaine.
- Trial name
- NCT04272086
- Testing
- Bupivacaine, Bupivacaine liposome, normal saline
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Fibroid Uterus, Sarcoma Uterus
Diagnostic Performances of Preoperative Echo-guided Uterine Biopsy in the Management of Suspect Uterine Sarcoma Tumors (BIOPSAR)
This is a prospective multi-center interventional study that will be performed in an effort to assess the diagnostic accuracy performance of preoperative vaginal ultrasound-guided biopsy (VUGB) to detect the exact histology of…
- Trial name
- BIOPSAR (NCT04250766)
- Testing
- Echo-guided uterine biopsy
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Institut Bergonié
Symptomatic Uterine Fibroids
Post Market TRUST - U.S.A. Study
This Post Market study is being conducted to compare the direct and indirect cost of three approaches (GFA, myomectomy, and uterine artery embolization) for the treatment of symptomatic uterine fibroids.
- Trial name
- NCT02163525
- Testing
- Global Fibroid Ablation (GFA), Abdominal or Laparoscopic Myomectomy, Uterine Artery Embolization (UAE)
- Where
- 9 sites in United States
- Volunteers
- 114 people
- Sponsor
- Acessa Health, Inc.