Clinical trials: Fertility Preservation
Transgenderism, Fertility Issues
Transgender Caregivers' and Patients' Representations of Parenthood as Part of a Fertility Preservation Pathway
This research aims to understand the impact of fertility preservation consultation on transgender patients' projection and how the possibility of preserving gametes influences transgender people's transition paths, parenthood…
- Trial name
- TransFert (NCT06218446)
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Patient Centredness, Quality of Life
Effect and Cost Evaluation of a Multifaceted Approach With a Patient-centredness Questionnaire in Fertility Care
The purpose of this study is to evaluate the effects and costs of a multifaceted approach on the patient-centredness of fertility care and the quality of life of fertility patients.
- Conditions
- Patient Centredness, Quality of Life, Risk Factors for Emotional Maladjustment
- Trial name
- NCT01481064
- Testing
- Multifaceted approach
- Where
- Netherlands
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- A.G. Huppelschoten
Fertility Preservation
Oocyte Cryopreservation
The specific aim of this study is to further develop methods of oocyte cryopreservation and evaluate their impact on reproductive outcomes.
- Trial name
- NCT01696786
- Testing
- Oocyte cryopreservation
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Fertility, Spermatic Parameters
Cryogenic Preservation of Spermatozoa
The reference technique for the conservation of gametes is storage in liquid nitrogen but new vats of nitrogen vapor (storage over liquid nitrogen) or in dry phase (storage in an insulated compartment of liquid nitrogen in a tank…
- Trial name
- NCT03734120
- Testing
- cryopreservation
- Where
- France
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Polycystic Ovary Syndrome, Ovarian Hyperstimulation Syndrome
In Vitro Maturation of Immature Oocytes
The aim of this study is to aspirate immature oocytes from antral follicles and mature the oocytes in vitro. These mature oocytes will serve for fertilization and the creation of embryos which will be replace in the uterus as…
- Trial name
- NCT00480337
- Testing
- In Vitro Maturation of immature oocytes
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Effects of Chemotherapy, Premature Ovarian Failure
Ovarian Reserve After Cancer: Longitudinal Effects
Women of reproductive age who will receive treatment for cancer that includes chemotherapy may participate in a study measuring ovarian function over time.
- Trial name
- ORACLE (NCT02467231)
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Gender Dysphoria, Adolescent
Fertility Preservation for Transfeminine Adolescents Via Semen Cryopreservation or Testicular Sperm Extraction
The goal of this observational cohort study is to identify and predict parameters for successful testicular sperm extraction (TESE) procedures or semen cryopreservation more accurately and to evaluate the decision making process…
- Trial name
- TESE (NCT06400199)
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Healthy, Male Infertility
Expanding Fertility Care to Poor and Low Resourced Settings Study
The investigators currently lack an understanding of barriers to completing the male factor infertility evaluation. Furthermore, as the investigators continue to expand access to fertility treatment particularly within…
- Conditions
- Healthy, Male Infertility, Infertility, Male, Fertility Disorders
- Trial name
- EXPLORE (NCT05205733)
- Testing
- Mail-in semen analysis kit
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Effects of Chemotherapy
Ovarian Freezing Before Cancer Treatment
Women of reproductive age who will undergo cancer treatment may participate in a study to surgically remove ovarian tissue and store it, frozen, for their potential use in the future.
- Trial name
- NCT01057745
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
DSD, 46,XY, DSD, Ovotesticular
Gonadal Tissue Cryopreservation for Fertility Preservation in Children With a Disorder of Sex Development
The purpose of this study is to offer gonadal tissue freezing and storage to children who are diagnosed with a disorder of sex development (DSD), who are at increased risk of infertility and certain malignancies (cancer).
- Conditions
- DSD, 46,XY, DSD, Ovotesticular, DSD, Sex Chromosome, Disorders of Sex Development
- Trial name
- DSD (NCT06692049)
- Testing
- Gonadectomy
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Erin Rowell
Benign Ovarian Cyst
Intra-operative Ultrasound Guided Laparoscopic Ovarian Cystectomy as a Method of Fertility Preservation
Title: Intra-operative ultrasound guided laparoscopic ovarian cystectomy (UGLOC) as a method of fertility preservation in the management of benign ovarian cysts.
- Trial name
- UGLOC (NCT05032846)
- Testing
- Ultrasound guided laparoscopic ovarian cystectomy, Laparoscopic Ovarian Cystectomy
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Minimal Residual Disease, Fertility Preservation
Contamination of Ovarian Tissue by RT-PCR in Participants With Solid Tumors
For prepubertal patients, cryopreservation of ovarian tissue is the only option available to preserve their fertility before cancer treatment.
- Trial name
- OVAMAR (NCT02400827)
- Testing
- malignant cells
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
HIV, Infertility
HIV and Ovarian Reserve
Recent evidence suggests a decline in fertility of persons living with HIV (PLWH) (delayed pregnancies, sponteanous abortions, especially when patients receive an antiretroviral therapy, early menopause, amenorrhea and…
- Trial name
- VIHRO (NCT03572270)
- Testing
- AMH test, pelvic ultrasound
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Infertility, Female
Physical Activity and Fertility Care Study
Randomized control trial to determine if performing the US Health and Human Services recommended amount of weekly physical activity during ovarian stimulation will differentially affect mental health or clinical outcomes of…
- Trial name
- PACE (NCT04002414)
- Testing
- Sufficient physical activity, Insufficient physical activity
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Breast Neoplasm Female, Fertility Preservation
Web-based Oncofertility Support Tool for Reproductive-age Women With Breast Cancer
The aim of this study was to develop electronic systems (e-systems) for oncofertility support, and to examine the comprehensibility, feasibility, usability, and effects on social support and preparation for decision-making.
- Trial name
- NCT05100498
- Testing
- Web-based oncofertility support tool
- Where
- Taiwan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mackay Medical College
Fertility Preservation
Vitrification of Oocytes Matured by CAPA-IVM
It has been reported that the potential of In Vitro matured oocytes might be affected by the vitrification process. In fact, the freezing and thawing procedures routinely used in IVF laboratories, have not yet been adapted to…
- Trial name
- NCT06157619
- Testing
- Oocyte Vitrification /Warming
- Where
- Peru
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centro de Fertilidad y Reproducción Asistida, Peru
Fertility Issues
Follicular FSH Serum Level as a Predictor of an Oocyte Yield and Quality in Fertility Preservation Cycles for Women With a Compromised Ovarian Reserve
The incorporation of ovarian reserve tests in IVF management started after initial publications indicating a potential role for basal FSH in predicting pregnancy outcome after IVF and in counseling patients (1,2).
- Trial name
- NCT05536999
- Testing
- Blood sample taking , like to measure hormonal level like LH, FSH, Perlakan ,in a follicular fluid after the oocyte retrival
- Where
- Israel
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Azoospermia, Elasticity Imaging Techniques
Testicular Elastography for Microscopic Testicular Sperm Extraction
Before commencing our study, we obtained approval from the local ethics committee. The study focused on patients who visited our urology outpatient clinic for infertility between January 2020 and March 2021.
- Conditions
- Azoospermia, Elasticity Imaging Techniques, Fertility Preservation
- Trial name
- NCT06524258
- Testing
- testicular elastography
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Uşak University
Fertility
Oocyte Cryopreservation
The purpose of this investigation is to offer the opportunity for young women to cryopreserve (freeze) their oocytes (eggs) for use with IVF at a later point in time.
- Trial name
- egg freezing (NCT01232972)
- Testing
- vitrification of oocytes
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Infertility, Obesity
IVF Outcome After Bariatric Surgery
This case-control study compares IVF results and live birth rates in women undergoing IVF with a history of bariatric surgery as compared to 2 age-matched control groups composed of (A) non-operated women matched on cases'…
- Trial name
- NCT02884258
- Where
- France
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Clinique Mathilde