Clinical trials: Fertility
Infertility, Emotional Disorder
Online Prevention of Emotional Disorders in Women Undergoing Fertility Treatments
The main aim of this pilot study is to study the clinical utility and acceptability of a transdiagnostic psychological intervention, the Unified Protocol, delivered in online format to prevent the onset of emotional disorders in…
- Conditions
- Infertility, Emotional Disorder, Anxiety Depression
- Trial name
- RE-FER moodle (NCT06420674)
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Jorge Javier Osma López
Fertility, Male Fertility
Sperm, Exposure and Endocrine Disruptors
The proposed research aims to 1) measure male participants' urinary levels of EDCs and sperm quality before and after report-back and EDC reduction intervention and assess changes, 2) assess the extent to which MM's program…
- Conditions
- Fertility, Male Fertility, Sperm Count, Low, Sperm Quality
- Trial name
- SEED (NCT07703046)
- Testing
- EDC Education Intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Million Marker Wellness, Inc.
Endometriosis
The North-West Inter Regional Female Cohort for Patients With Endometriosis
All women managed for endometriosis are included and followed up through the CIRENDO database. Information is obtained from surgical and histological records and from self-questionnaires completed before surgery.
- Trial name
- CIRENDO (NCT02294825)
- Testing
- various surgical procedures in endometriosis
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Rouen
Fertility Preservation in Transgender Persons
Attitudes and Decision Regret Regarding Fertility Preservation in Transgender Individuals
The goal of this observational survey is to learn how transgender adults think and feel about saving their fertility before gender-affirming treatment.
- Trial name
- Fertilitrans (NCT07194226)
- Testing
- No intervention (observational study)
- Where
- Italy
- Volunteers
- 616 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Fertility
Effect of GnRH Antagonist vs Agonist Long on IVF Outcome, Peak Estradiol Level,and Duration of Stimulation
The purpose of this study is to determine if utilizing GnRH antagonists versus agonist long protocol during controlled ovarian stimulation (COH) with human-derived gonadotropins for assisted reproduction affects IVF outcome, peak…
- Trial name
- NCT01669291
- Testing
- Bravelle and Menopur, Agonist, Antagonist
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Main Line Fertility Center
Infertility, Male
The Effect of a Multimodal Lifestyle Program on Male Fertility
A non-pharmacological study, which examines the effect of lifestyle intervention on sperm quality among men in fertility treatment.
- Trial name
- NCT04761250
- Testing
- Lifestyle
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Classic Congenital Adrenal Hyperplasia
Fertility and Pregnancy in Patients With Classic Congenital Adrenal Hyperplasia
Classic congenital adrenal hyperplasia (CAH) is a rare genetic endocrine disorder. Its prevalence is around 1/15.000. It results from a deficiency in 21-hydroxylase, an adrenal steroidogenic enzyme involved in the biosynthesis of…
- Trial name
- FERTI-HCS (NCT06153043)
- Testing
- Women patients with classical congenital adrenal hyperplasia
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Hospices Civils de Lyon
Infertility, Egg Freezing
Egg Freezing Pilot Study
University Reproductive Associates is conducting a pilot study to study the technique of egg freezing. Your participation in this study will provide us with important information to allow us to offer this technology for women…
- Trial name
- NCT00839839
- Testing
- Oocyte Vitrification
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University Reproductive Associates
Infertility, Female
RCT of Ethiodized Poppyseed Oil VS the Second-generation Non-ionic Monomer Contrast in Hysterosalpingography of Infertile Patients.
This study evaluates the difference of imaging diagnostic quality and fertility promoting effect in the diagnosis and treatment of infertility by hysterosalpingography between using ethiodized poppyseed oil and the…
- Trial name
- NCT03370575
- Testing
- ethiodized poppyseed oil, the second-generation non-ionic monomer contrast
- Where
- 13 sites in China
- Volunteers
- 900 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Chronic Hepatitis, C Virus
Efficacy Study to Evaluate the Effect of New Antiviral Drugs on HCV Infection.
The purpose of this study is to determinate the AMH levels before and after antiviral therapy with Ombitasvir-Paritaprevir-Ritonavir and Dasabuvir in comparison with age-matched HCV-positive women not undergoing antiviral…
- Trial name
- NCT02950870
- Testing
- Ombitasvir-Paritaprevir-Ritonavir, Dasabuvir, Ribavirin
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- University of Modena and Reggio Emilia
Fertility Disorders, Infertility
Performance Assessment of the MAGENTA Blast Algorithm for Embryo Prediction
This is a retrospective, observational, single-arm, multi-center study to evaluate the predictive performance of MAGENTA BLAST, an artificial intelligence (AI)-enabled software application, when used as analytical, adjunctive…
- Trial name
- NCT07464275
- Testing
- MAGENTA Blast
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- Future Fertility Inc.
Cancer, Autoimmune Disorders
Testicular Tissue Cryopreservation for Fertility Preservation
Testicular tissue cryopreservation is an experimental procedure where a young boy's testicular tissue is retrieved and frozen. This technique is reserved for young male patients who are not yet producing mature sperm, with the…
- Trial name
- NCT02972801
- Testing
- Testicular biopsy
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- University of Pittsburgh
Ovulation, Female Fertility
FemiClock: Non-invasive Tools Development (Salivary and Hair Progesterone) for Ovulation Detection in Heathy Women With Regular Menstrual Cycles Without Contraception.
Currently, the gold standard to confirm ovulation is measuring LH and/or progesterone in blood. However, because confirmation requires a blood sample, this approach is not suitable for epidemiological studies evaluating the…
- Conditions
- Ovulation, Female Fertility, Menstrual Cycle
- Trial name
- FemiClock (NCT07687823)
- Testing
- Diagnostic Test: Non-invasive ovulation biomarker assessment - Smartwatch, Diagnostic Test: Non-invasive ovulation biomarker assessment - Questionnaires, Hormonal blood assessment
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Pregnancy, Fertility
Creighton Model Effectiveness, Intentions and Behaviors Assessment (CEIBA)
The Creighton Model (CrM) FertilityCare System is a natural family planning method that teaches couples to recognize and chart the signs of fertility and infertility in the woman's cycle and to use that knowledge to either…
- Trial name
- CEIBA (NCT01012596)
- Testing
- Creighton Model System of Natural Family Planning
- Where
- 18 sites in United States, Canada
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- University of Utah
Infertility, Infertility Secondary
Sperm Preparation Prior to Intrauterine Insemination Study
This is a randomized controlled trial comparing density gradient centrifugation and microfluidic sperm sorting in patients undergoing intrauterine insemination to evaluate cumulative pregnancy outcomes.
- Conditions
- Infertility, Infertility Secondary, Infertility Unexplained, Anovulation
- Trial name
- PIoUS (NCT05693220)
- Testing
- Zymot Multi sperm separation device, Density gradient centrifugation
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of California, San Francisco
Breast Cancer and Pregnancy
Registry Study of Pregnancy and Breast Cancer
An ambispective observational registry study of pregnancy and breast cancer
- Trial name
- EMBARCAM (NCT04603820)
- Where
- 28 sites in Spain
- Volunteers
- 866 people
- Sponsor
- Spanish Breast Cancer Research Group
Fertility, Spermatic Parameters
Cryogenic Preservation of Spermatozoa
The reference technique for the conservation of gametes is storage in liquid nitrogen but new vats of nitrogen vapor (storage over liquid nitrogen) or in dry phase (storage in an insulated compartment of liquid nitrogen in a tank…
- Trial name
- NCT03734120
- Testing
- cryopreservation
- Where
- France
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Rheumatologic Diseases, Ovarian Reserve
Assessment of Ovarian Reserve in Women With Rheumatologic Diseases
Our infertility unit has started a clinic for women with rheumatological diseases. those women are prone to infertility problems and it might be due to their illness or cytotoxic treatment .
- Conditions
- Rheumatologic Diseases, Ovarian Reserve, Infertility
- Trial name
- NCT02273869
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Meir Medical Center
Infertility Female
The Effect of Metformin on Fecundability in an ART(Assisted Reproductive Technology) Setting - the Correlation to Uterine Flows
The basis for obesity's impact on reproduction is not well characterised and there is a controversy whether the key organ influenced by it are the ovaries or the uterus.
- Trial name
- NCT02848950
- Testing
- Metformin
- Volunteers
- 100 people
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Infertility
The Cost-effectiveness of Hysterosalpingography Versus Hysterosalpingo-foam Sonography During Fertility Work-up
Hysterosalpingography (HSG) and hysterosalpingo-foam sonography are two methods to assess tubal patency during fertility work-up.
- Trial name
- FOil (NCT05882188)
- Testing
- Oil-based contrast, ExEm Foam
- Where
- Netherlands
- Volunteers
- 1,102 people
- Sponsor
- Amsterdam UMC, location VUmc