Clinical trials: Fertility, Male
Disorders of Sex Development (DSD), Pediatric and Adolescent Cancers of the Genital Tract
Data Collection Study of Pediatric and Adolescent Gynecology Conditions
Background: Gynecologic conditions are those that are related to the reproductive system. They can be reproductive gland disorders or reproductive system tumors. They can also be inborn anomalies of the reproductive tract.
- Conditions
- Disorders of Sex Development (DSD), Pediatric and Adolescent Cancers of the Genital Tract, Reproductive Endocrine Conditions in Puberty, Structural Gynecologic Conditions Including Vulvar and Vaginal Conditions
- Trial name
- NCT04717349
- Where
- United States
- Volunteers
- 11,000 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Gout
The Influence of Urate-lowering Therapy on Sperm Quality of Male Gouty Patients：A Prospective Cohort Study
Gout is a kind of crystal-associated arthropathy caused by monosodium urate deposition, which is directly related to hyperuricemia caused by purine metabolic disorder and/or decreased uric acid excretion.
- Trial name
- INITIAL (NCT04213534)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Satisfaction Survey, Fertility Perservation
Survey of Patients Who Received Fertility Preservation Counseling and Underwent Testicular Tissue Cryopreservation Prior to Gonadotoxic Treatment During Childhood or Peripuberty
Chemotherapy and radiotherapy can lead to spermatogonial stem cell depletion in pre- and peripubertal boys, potentially resulting in infertility during adulthood A testicular biopsy is considered a safe procedure performed in…
- Trial name
- QUALIFERT (NCT07140549)
- Testing
- Survey using a questionnaire.
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Fertility, Male Cancer
Outcomes for Patients Who Preserved Their Fertility as Part of Cancer Treatment at the Center for the Study and Preservation of Eggs and Sperm: MaPreservFerti
Improvements in diagnostic methods and cancer treatments have led to a steady increase in survival rates. The 5-year survival rate for men diagnosed with cancer between the ages of 15 and 39 has exceeded 81%.
- Conditions
- Fertility, Male Cancer, Oncofertility
- Trial name
- MaPreservFerti (NCT07601451)
- Testing
- Patient self-assessment form
- Where
- France
- Volunteers
- 950 people
- Sponsor
- Hospices Civils de Lyon
Infertility, Quality of Life
Decisional Process in Male Fertility Preservation
The survey analyses how to improve the decision-making process for fertility preservation in the pediatric population based on 1. patient and parent feelings about fertility preservation counselling 2.
- Conditions
- Infertility, Quality of Life, Cancer
- Trial name
- NCT02411214
- Testing
- survey
- Volunteers
- 348 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Testis, Infertility
TNFSF11 Inhibition and Fertility: a Prospective Study
The receptor activator of NF-kB ligand (RANKL) system is considered important for bone homeostasis and comprises three important factors.
- Conditions
- Testis, Infertility, Sperm
- Trial name
- NCT02422108
- Testing
- Denosumab
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Martin Blomberg Jensen
Healthy
A Study to Compare Two Different Tablet Formulations of AZD8931 in Healthy Males and Females
A study to compare two different tablet formulations of AZD8931 in healthy males and females.
- Trial name
- NCT01330758
- Testing
- AZD8931
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Male Infertility
Home Semen Analysis Tests As a Screening Tool for Fertility Patients
Infertility, defined as the inability to conceive after 12 months of regular unprotected intercourse, is estimated to affect 1 in 7 heterosexual couples.
- Trial name
- NCT06188936
- Testing
- ExSeed®, Survey
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Overweight, Obesity
Effect of Weight Loss on Reproductive Function in Overweight Men
Obesity has been found to be a risk factor for female infertility. Studies have indicated that obese men often have poor semen quality and require increased time to make partner pregnant.
- Trial name
- NCT00934765
- Testing
- weight loss
- Where
- Norway
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oslo University College
Asthenozoospermia
Effect of Pentoxifylline + CoQ10 vs CoQ10 Alone on Sperm Motility in Subfertile Men With Asthenozoospermia
The goal of this clinical trial is to learn if drug Pentoxifylline plus Coenzyme Q10 work to treat asthenozoospermia in subfertile male. It will also learn about the safety of drug Pentoxifylline plus Coenzyme Q10.
- Trial name
- NCT07252518
- Testing
- Coenzyme Q 10, Pentoxifylline 400 MG Oral Tablet
- Where
- Bangladesh
- Volunteers
- 56 people
- Sponsor
- Mst.Sumyara Khatun
Azoospermia, Elasticity Imaging Techniques
Testicular Elastography for Microscopic Testicular Sperm Extraction
Before commencing our study, we obtained approval from the local ethics committee. The study focused on patients who visited our urology outpatient clinic for infertility between January 2020 and March 2021.
- Conditions
- Azoospermia, Elasticity Imaging Techniques, Fertility Preservation
- Trial name
- NCT06524258
- Testing
- testicular elastography
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Uşak University
Klinefelter Syndrome
Fertility Preservation in Cases of Klinefelter Syndrome.
Klinefelter Syndrome (KS) is the most common sex chromosomal abnormalities (1/600 newborn males), and is characterized by a hypergonadism hypogonadism.
- Trial name
- FERTIPRESERVE (NCT01918280)
- Testing
- Seminal analyses and testicular biopsy
- Where
- 4 sites in France
- Volunteers
- 141 people
- Sponsor
- Hospices Civils de Lyon
Male Fertility, Testicular
Use of the SiDTM v2.0 Algorithm to Assist Embiyologists in Sperm Selection During ICSI Procedures
Infertility is defined as a failure of a couple to achieve a pregnancy after 12 or more months of unprotected intercourse. Males are found to be solely responsible for 20-30% of infertility cases but contribute to 50% of cases…
- Conditions
- Male Fertility, Testicular, Sperm Parameters in Fertile and Infertile Men, Sperm Selection
- Trial name
- SID_3 (NCT07163754)
- Testing
- Automated Sperm Selection, Conventional Sperm Selection
- Volunteers
- 100 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Childhood Cancer, Fertility Disorders
Male Fertility Preservation Using Cryopreservation of Testicular Tissue Before Highly Gonadotoxic Cancer Treatment
Background: Due to the remarkable improvement in treatments these last decades, long term survival can be expected in more than 80% of childhood cancer patients.
- Trial name
- NCT03180918
- Testing
- testicular tissue biopsy
- Where
- 3 sites in Switzerland
- Volunteers
- 100 people
- Sponsor
- Gumy-Pause Fabienne
Infertility, Female, Infertility, Male
Knowledge and Attitude Towards Fertility Among Emirati Infertile Patients
Infertility is on the rise worldwide due to multiple reasons. Proper and timely diagnosis makes the treatment easier and more acceptable by the couple.
- Trial name
- NCT06250231
- Testing
- No intervention
- Where
- 2 sites in United Arab Emirates
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Klinefelter Syndrome
Klinefelter Fertility Preservation
Klinefelter syndrome occurs in 1 in 600 males and is a common cause of infertility in men. It appears scar tissue forms in these boys' testicles, leading to progressive destruction over their lifetimes.
- Trial name
- NCT01817296
- Testing
- Testicular Biopsy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Boston Children's Hospital
Male Infertility, Low Sperm Quality
A Clinical Trial to Evaluate the Effects of a Supplement on Markers of Male Fertility
This study will evaluate the effects of the WeNatal For Him supplement on markers of male fertility over a 3-month period. The trial is a single-arm, unblinded study enrolling 40 male participants who will take 3 capsules of the…
- Conditions
- Male Infertility, Low Sperm Quality, Low Testosterone, Low Energy
- Trial name
- NCT07740161
- Testing
- WeNatal For Him Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- WeNatal
Male Infertility, Infertility
The Therapeutic Effects of Bu Shen Yi Jing Pill on Semen Quality in Sub Fertile Males: a Randomized Controlled Trial
This study aims to evaluate the safety and efficacy of Bu Shen Yi Jing (BSYJ) Pill , a type of traditional Chinese medicine, in improving male subfertility and semen parameters.
- Conditions
- Male Infertility, Infertility, Traditional Chinese Medication (TCM), Reproductive Issues
- Trial name
- NCT05290558
- Testing
- Bu Shen Yi Jing Pill
- Where
- Singapore
- Volunteers
- 59 people
- Sponsor
- KK Women's and Children's Hospital
Sperm DNA Fragmentation, Male Fertility
Impact of Telomere Biology and Sperm DNA Fragmentation on Embryonic Development
The proposed project we intend to assess the implication of the telomeric pathway in male infertility. To get this, several analyzes will be carried out: 1. Determination of the TL by means of two methods: Q-FISH and PCR. 2.
- Conditions
- Sperm DNA Fragmentation, Male Fertility, Telomeres, Sperm
- Trial name
- NCT05508217
- Where
- Spain
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Inguinal Hernia Bilateral
Inguinal Hernia Repair and Male Fertility
General objective: To evaluate the fertility of adult men submitted to bilateral herniorrhaphy with mesh placement by the Lichtenstein and laparoscopic approaches
- Trial name
- NCT05799742
- Testing
- Bilateral hernioplasty
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital