Clinical trials: Fertility, Male
Healthy
A Study to Compare Two Different Tablet Formulations of AZD8931 in Healthy Males and Females
A study to compare two different tablet formulations of AZD8931 in healthy males and females.
- Trial name
- NCT01330758
- Testing
- AZD8931
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
Study to Assess Safety, Tolerability and Pharmacokinetics After Single Doses of AZD1446 to Healthy Volunteers
The primary purpose of this study is to assess the safety and tolerability of AZD1446 following single dose administration.
- Trial name
- SAD (NCT00803855)
- Testing
- AZD1446
- Where
- Sweden
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Fertility, Fertility, Male
Plan A Occlusion and Reversal System Feasibility Study
Prospective, multicenter, single-arm, open label, interventional clinical trial investigating the safety and effectiveness of the Plan A Male Contraceptive System to occlude the vas deferens to block the passage of sperm and then…
- Conditions
- Fertility, Fertility, Male, Healthy Male Adults
- Trial name
- NCT07361120
- Testing
- Occlusion System
- Where
- 3 sites in Australia, Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Next Life Sciences
Healthy
Study to Investigate Safety, Tolerability and Pharmacokinetics With Single and Multiple Ascending Doses of AZD1446
This study is designed to evaluate the safety, tolerability and PK of AZD1446 in Subjects when given as multiple dose administration for either 7 Days (Day 1 single dose, Day 2-6 multiple doses) in Part A and optionally at…
- Trial name
- NCT00902993
- Testing
- AZD1446
- Where
- 2 sites in Sweden
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
Study to Investigate Multiple Ascending Oral Doses of AZD5213 in Healthy Male and Non Fertile Female Subjects
1. The main purpose of this study is to assess the safety and tolerability of AZD5213 after multiple oral doses. 2. Another purpose of this study is to evaluate the pharmacokinetics (also called PK - how the study drug enters and…
- Trial name
- NCT01171105
- Testing
- AZD5213
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Fertility, Male Fertility
Sperm, Exposure and Endocrine Disruptors
The proposed research aims to 1) measure male participants' urinary levels of EDCs and sperm quality before and after report-back and EDC reduction intervention and assess changes, 2) assess the extent to which MM's program…
- Conditions
- Fertility, Male Fertility, Sperm Count, Low, Sperm Quality
- Trial name
- SEED (NCT07703046)
- Testing
- EDC Education Intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Million Marker Wellness, Inc.
Healthy Elderly Volunteers, Mild-to-moderate Alzheimer's Disease Patients
A Two-part Multiple Dose Study to Assess the Safety and Effects of AZD3293 in Healthy Elderly and Alzheimer's Patients
This is a two-part multiple dose study in healthy male and female (of non-child bearing potential) elderly volunteers, and in Alzheimer's disease patients, to assess the safety, effects on the body, and blood, CSF, and urine drug…
- Trial name
- NCT01795339
- Testing
- AZD3293
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Volunteers, Pharmacologic Action
Relative Bioavailability Study to Assess Two Solid Formulations Compared to an Oral Solution of AZD3293 in Healthy Male and Non-Fertile Female Subjects
This is an open-label, randomized, 3-period crossover, single dose study. Three (3) single doses of AZD3293 (2 different tablet formulations, and an oral solution) will be administered with a washout period of at least 1 week…
- Trial name
- BA (NCT02039180)
- Testing
- AZD3293 oral solution, AZD3293 tablet formulation A, AZD3293 tablet formulation B
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Effect of Hyperandrogenism on IVF Outcomes in PCOS Patients
Ovulatory dysfunction affects 18 to 25% of infertile women, the most common identifiable condition is polycystic ovarian syndrome (PCOS).
- Trial name
- HIP (NCT05555680)
- Testing
- Ferriman-Gallwey Score
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Clinique Ovo
Fertility, Male, Sub-Fertility, Male
Study of the Consumer Use of a New Home Test to Measure Sperm Concentration
The objective of the study is to evaluate the agreement in measurement of sperm concentration in human semen between lay users with TRAK and a recognized reference method.
- Trial name
- NCT02475395
- Testing
- TRAK device
- Where
- 3 sites in United States
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Sandstone Diagnostics
Healthy Volunteer
AZD2423 Single Ascending Dose Study in Healthy Japanese Subjects
This is a Phase I, single centre, randomised, double-blind, placebo-controlled, parallel group study to assess the safety, tolerability and pharmacokinetics of AZD2423 following single ascending dose administration to healthy…
- Trial name
- JSAD (NCT00970775)
- Testing
- AZD2423
- Where
- 2 sites in United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
Positron Emission Tomography (PET) Study
The primary purpose is to study the occupancy at the α4β2 neuronal nicotinic receptor's (NNRs) and to determine the relation between plasma concentration of AZD1446 and the occupancy at α4β2 NNRs.
- Trial name
- NCT00886067
- Testing
- AZD1446, 2-[18F]-F-A85380
- Where
- Sweden
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Male Infertility, Low Sperm Quality
A Clinical Trial to Evaluate the Effects of a Supplement on Markers of Male Fertility
This study will evaluate the effects of the WeNatal For Him supplement on markers of male fertility over a 3-month period. The trial is a single-arm, unblinded study enrolling 40 male participants who will take 3 capsules of the…
- Conditions
- Male Infertility, Low Sperm Quality, Low Testosterone, Low Energy
- Trial name
- NCT07740161
- Testing
- WeNatal For Him Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- WeNatal
Infertility, Male
The Effect of Supplementation With Fish Oil (EPAX EVOLVE 05) on Sperm Quality
The study will enrol men that have a poor sperm quality. They will take either a placebo or fish oil capsule (2 per day) for 3 months.
- Trial name
- NCT06950203
- Testing
- Very Long Chain Polyunsaturated Fatty Acids, Comparator arm (DHA)
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Epax Norway AS
Hypogonadism
Influence of Administration Route of Testosterone on Male Fertility
Exogenously administered testosterone will override the normal negative feedback of endogenous testosterone on the hypothalamus and pituitary.
- Trial name
- NCT00705796
- Testing
- MPP10, testosterone, Testosterone
- Where
- Netherlands
- Volunteers
- healthy volunteers welcome
- Sponsor
- Acerus Pharmaceuticals Corporation
Hypertension, Pulmonary
The Effect of Tracleer® on Male Fertility
The objective of the study is to evaluate the effects of chronic TRACLEER® treatment on testicular function via semen analysis in male patients with primary pulmonary arterial hypertension (PAH).
- Trial name
- NCT00082186
- Testing
- bosentan
- Volunteers
- 22 people
- Sponsor
- Actelion
Part A Healthy Young Males and Non-fertile Female Volunteers Aged 20 to 45 Years., Part B Healthy Young Males and Non-fertile Female Volunteers Aged 20 to 45 and Elderly Volunteers Aged 60 to 80
To Investigate the Safety, Tolerability and Pharmacokinetics of AZD2516 After Multiple Dosing in Healthy Volunteers
AZD2516 is being developed for the oral treatment of chronic neuropathic pain. This study is split in to two parts. Part A will measure the effect of food and a new formulation of the drug in the blood and see how well it is…
- Trial name
- NCT01148095
- Testing
- AZD2516
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Virtual Reality
Erotica by Virtual Reality on Sperm Donors
Objective To study whether erotica by virtual reality (VR) during masturbation influences the quality of sperm donor ejaculates. Hypothesis Erotica by virtual reality improves ejaculate quality.
- Trial name
- NCT05457764
- Testing
- Virtual reality headset
- Where
- 4 sites in Denmark
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cryos International
Healthy Young Volunteers, Healthy Elderly Volunteers
A Single Dose Study to Assess the Safety, Effects, and Blood and Urine Drug Levels of AZD3293 in Healthy Subjects
This is a single dose study in healthy male and female (of non-child bearing potential) volunteers, to assess the safety, effects on the body, and blood and urine drug levels of AZD3293.
- Trial name
- NCT01739647
- Testing
- AZD3293
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Infertility
Hormone-free Antral Retrieval for Viable Embryo Storage & Transfer
This study is testing whether eggs can be collected from small follicles without using the usual ovarian stimulation medications. Participants will have up to three egg retrieval procedures.
- Trial name
- HARVEST (NCT07801105)
- Testing
- CAPA-IVM System, Serial Unstimulated Transvaginal Oocyte Retrieval, ICSI, Blastocyst Culture, PGT-A, Embryo Vitrification/Accumulation, and Single Euploid Embryo Transfer
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kevin Doody