Clinical trials: Female
Female Breast Cancer Patients, Histopathologically Confirmed Advanced HR +/HER2-invasive Breast Cancer
Adebrelimab Combined With Fluzoparib in HRD-positive HR +/HER2- Advanced Breast Cancer
This is an open-label, single-arm, exploratory study planned to include 40 patients with HRD-positive HR +/HER2- advanced breast cancer treated with Adebrelimab in combination with fluzoparib.
- Conditions
- Female Breast Cancer Patients, Histopathologically Confirmed Advanced HR +/HER2-invasive Breast Cancer, HRD Positive Advanced Breast Cancer
- Trial name
- NCT06254066
- Testing
- Adebrelimab plus Fluzoparib
- Volunteers
- 40 people
- Sponsor
- Zhejiang Cancer Hospital
Breast Cancer Female
CLI and FAR for Intraoperative Margin Assessment
This study is a prospective, single arm interventional study to evaluate the diagnostic accuracy of intraoperative Cerenkov luminescence imaging (CLI) plus flexible autoradiography (FAR) using the LightPath® Imaging System for…
- Trial name
- CLI-FAR (NCT05496101)
- Testing
- Intraoperative CLI + FAR LightPath imaging
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- King's College London
Female Infertility
Hormonal Monitoring and Progesterone Adjustment in Frozen Embryo Transfer Cycles
Hormonal monitoring impact on overall pregnancy rate in frozen embryo transfer (FET)cycles and hence progesterone supplement adjustments remain debatable in current literature.
- Trial name
- NCT05189145
- Testing
- estradiol valerate, Hormonal monitoring progesterone, estradiol, luteinizing hormone, transvaginal ultrasound examination
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Alexandria University
Sustainability, Female Infertility
Greening the Humanitas Fertility Center: How to Build a More Sustainable Medical Daily Routine
The goal of this observational study is to redefine an everyday clinical routine at the Humanitas Fertility center calculating the effects derived from the reduction of inappropriate and avoidable tests, procedures, tools and…
- Trial name
- Green (NCT06239051)
- Where
- Italy
- Volunteers
- 136 people
- Sponsor
- Istituto Clinico Humanitas
Breast Cancer Female
Tele-nursing Practices Based on Technological Competence Theory in Breast Cancer Patients
This research is a randomized controlled double-blind experimental study aiming to evaluate the effect of tele-nursing practices based on technological competence theory on empowerment status and symptom management self-efficacy…
- Trial name
- NCT05998655
- Testing
- tele nursing
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ataturk University
Breast Neoplasm Female
A Prospective, Open, Multicenter Single-arm Clinical Studie of Docetaxel, Carboplatin Combined With Inetetamab and Pyrotinib in the Treatment of Local-advanced HER2-positive Breast Cancer
This study is a prospective, open, multi-center, single arm trial. The treatment group will receive six cycles of docetaxel, carboplatin combined with Inetetamab and Pyrotinib before surgery.
- Trial name
- neoPICD (NCT06234137)
- Testing
- Docetaxel, Carboplatin, Inetetamab
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Wang Ouchen
Breast Cancer Female
21DIF039: Prone to Supine Breast MRI II, P2S2 Breast MRI Trial
The purpose of this study is to determine whether a supine breast MRI obtained with a second intravenous injection of gadolinium contrast immediately after a standard clinical prone breast MRI will provide sufficient tumor…
- Trial name
- 21DIF039 (NCT05131607)
- Testing
- Supine MRI
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
ERAS, Gynecologic Cancer
Adherence and Compliance to ERAS in Gynecological Surgery
The aim of the study is to investigate the association between early non-compliance to ERAS in postoperative day 2 (POD2) with the rate of postoperative complications.
- Conditions
- ERAS, Gynecologic Cancer, Post Operative Pain, Ovarian Cancer
- Trial name
- ERASGYNBS002 (NCT05738902)
- Testing
- Assessment of compliance to ERAS.
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Breast Cancer Female, Breast Neoplasms
Intra-operative PET-CT: a Novel Approach to Determine Excision Margins in Lumpectomy Breast Cancer.
Examination of the feasibility of intra-operative pet CT to detect surgical margins in breast conservative surgery to prevent re-excision.
- Trial name
- NCT04343079
- Testing
- PET CT
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Breast Cancer Female, Peripheral Neuropathy
"Prevention of Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer Patients"
The aim of this study is to evaluate the effect of pentoxifylline 400 mg twice daily administration on the prevention of paclitaxel-Induced peripheral neuropathy in breast cancer patients.
- Trial name
- NCT05189535
- Testing
- Pentoxifylline, Paclitaxel
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Ain Shams University
Female Infertility
The Embryologist's Impact on Blastocyst Vitrification and Thawing
The goal of this monocentric retrospective observational study is to analyse, for the first time in literature, the role of the embryologist who freezes and thaws the embryos.
- Trial name
- NCT06220227
- Testing
- vitrification and thawing procedures
- Where
- Italy
- Volunteers
- 6,800 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Female Athlete Triad
Energy Deficiency and Athletic Performance
Energy availability (EA) refers to the balance between daily energy intake and exercise energy expenditure. Athletically inadequate EA is defined as low energy availability (LEA).
- Trial name
- NCT06220240
- Testing
- Modified Training Programme, Routine Training Programme
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Istanbul University - Cerrahpasa
Breast Cancer, Breast Cancer Female
Lymphedema Severity on Shoulder Joint Function and Muscle Activation Patterns in Breast Cancer Survivors
Breast cancer-related lymphedema (BCRL) is a common complication affecting the upper extremity following breast cancer treatment.
- Trial name
- NCT05934695
- Testing
- Lymphedema severity stratification
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ahram Canadian University
Infertility, Female
Recombinant FSH Investigation in the Treatment of Infertility With Assisted Reproductive Technology (ART) (RITA-2)
This trial investigates the effects of FE 999049 compared to placebo.
- Trial name
- RITA-2 (NCT03738618)
- Testing
- Follitropin delta
- Where
- 24 sites in United States
- Volunteers
- 588 people
- Sponsor
- Ferring Pharmaceuticals
Breast Cancer Female
Mind Programme for Women With Breast Cancer (Nationwide Coverage)
The purpose of this research project is to optimize the Mind programme for women with breast cancer, taking into consideration the results from its pilot study, and to testits efficacy and cost-effectiveness through a 3-arm…
- Trial name
- MIND(n) (NCT06212414)
- Testing
- Mind Programme, Support Group
- Where
- Portugal
- Volunteers
- 153 people
- Sponsor
- University of Coimbra
Other Female Genital, Cancer
Scheduled Triple-lumen Central Venous Catheter Exchange: A Prospective Controlled Randomized Study
CVC Pros and Cons of scheduled Triple-lumen Central Venous Catheter Exchange: A Prospective Controlled Randomized Study
- Trial name
- NCT00250809
- Testing
- Placement of a central venous catheter
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of New Mexico
Breast Cancer Female
Breast Lesion in CT Chest
The aims of this study are To evaluate the CT features of incidental breast lesions on chest CT and subsequently suggest useful criteria for referral to a specialized breast unit.
- Trial name
- NCT06196216
- Testing
- MSCT
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Malignant Female Reproductive System Neoplasm, Stage 0 Lung Cancer AJCC v8
Family Caregivers in Underserved Populations Providing Complex Cancer Care
This clinical trial develops and tests a model of family caregiver education focused on the role of underserved family caregivers as providers of complex care in the home.
- Conditions
- Malignant Female Reproductive System Neoplasm, Stage 0 Lung Cancer AJCC v8, Stage I Lung Cancer AJCC v8, Stage IA1 Lung Cancer AJCC v8
- Trial name
- NCT05213078
- Testing
- Educational Intervention, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Ultrasonography, Breast Neoplasm Female
Intelligent Remote Intervention for High-risk Breast Cancer Populations
The goal of this clinical trial is to compare the effects of modern remote health intervention regime with traditional in-person intervention strategies for high-risk breast cancer groups that with BI-RADS 3 or higher nodules.
- Conditions
- Ultrasonography, Breast Neoplasm Female, Breast Carcinoma, Health Education
- Trial name
- NCT06193707
- Testing
- the Remote Intervention, the Traditional Intervention
- Volunteers
- 1,250 people
- Sponsor
- Qianfoshan Hospital
Rectocele; Female
Long-term Results of the Stapled Transanal Rectal Resection (STARR) Operation Proposed in the Treatment of a Rectocele
Rectal static disorders, including the rectocele, represent a frequent functional pathology which affects the quality of life of affected patients.
- Trial name
- STARRLOC (NCT05037422)
- Testing
- STARR surgery
- Where
- France
- Volunteers
- 77 people
- Sponsor
- University Hospital, Grenoble