Clinical trials: Female
Lymphedema
Safety Study of Bevacizumab to Treat Women With a History of Breast Cancer and Suffering From Upper Extremity Lymphedema
The purpose of this study is to determine the safety and side effects of bevacizumab in subjects with lymphedema who will initially receive bevacizumab alone and then in combination with standard manual lymphatic drainage (MLD)…
- Trial name
- NCT00318513
- Testing
- Bevacizumab
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Premiere Oncology of Arizona
Renal Cell Carcinoma
RF Ablation of Treatment of Metastatic Lesions in Patients Undergoing Antiangiogenic Therapy for Stage IV Renal Cell Carcinoma
The purpose of this study is to look at the effects of a procedure called radiofrequency ablation on kidney tumors from patients who are undergoing antiangiogenic treatment.
- Trial name
- NCT00601120
- Testing
- Radiofrequency Ablation
- Where
- United States
- Sponsor
- Beth Israel Deaconess Medical Center
Overactive Bladder
Extension Study of Fesoterodine for Overactive Bladder Syndrome in Children.
The purpose of this study is to evaluate the long term tolerability of Fesoterodine and its efficacy for overactive bladder syndrome in children.
- Trial name
- FOXY2015 (NCT02614482)
- Testing
- Fesoterodine
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Stéphane Bolduc
Ovarian Cancer
FLABRA: Frontline Approach for BRCA Testing in OC Treatment naïve Population. A LATIN AMERICA Epidemiologic Study
This study aims to answer very important questions regarding the prevalence of somatic and germline mutations (sBRCAm and gBRCAm) in a population of newly diagnosed ovarian cancer patients from Latin America.
- Trial name
- FLABRA (NCT02984423)
- Where
- 27 sites in Argentina, Brazil and 4 more
- Volunteers
- 471 people
- Sponsor
- AstraZeneca
Cancer, Breast Cancer
A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors
The purpose of this study is to characterize the safety and tolerability of ALTA2618 in adults with AKT1 E17K-mutant advanced solid tumors.
- Conditions
- Cancer, Breast Cancer, Endometrial Cancer, Metastatic Cancer
- Trial name
- NCT06533059
- Testing
- ALTA2618
- Where
- 31 sites in United States, Australia and 6 more
- Volunteers
- 110 people
- Sponsor
- Alterome Therapeutics, Inc.
Prostate Cancer Stage I, Bladder Outlet Obstruction
Transurethral Prostate Enucleation in Surveillance Protocol for Low Risk Prostate Cancer
We will compare oncological and functional outcomes of anatomical endoscopic enucleation of the prostate (AEEP) versus continued medical treatment in low-risk prostate cancer patients for whom an active surveillance protocol was…
- Trial name
- NCT05631080
- Testing
- Anatomical Endoscpic enucleation of the Prostate
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
The Recipients Undergoing Liver Transplantation
Identification of Genetic Polymorphism Related to Acute Kidney Injury After Liver Transplantation Through Genome-wide Association Study (GWAS) in Korean Population
Some of the liver transplantation recipients experience postoperative acute kidney injury due to various causes including genetic factors.
- Trial name
- NCT03344380
- Where
- South Korea
- Volunteers
- 330 people
- Sponsor
- Yonsei University
Breast Neoplasms, Triple-Negative, Breast Neoplasm Malignant Female
Olaparib & Radiation Therapy for Patients Triple Negative Breast Cancer (TNBC)
A Phase I of Olaparib with Radiation Therapy in Patients With Inflammatory, Loco-regionally Advanced or Metastatic TNBC (triple negative breast cancer) or Patient With Operated TNBC with Residual Disease.
- Conditions
- Breast Neoplasms, Triple-Negative, Breast Neoplasm Malignant Female, Radiotherapy Side Effect
- Trial name
- RadioPARP (NCT03109080)
- Testing
- Olaparib, Radiation therapy
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Institut Curie
Endometriosis
The Effect of Medical Management Following Excisional Surgery for Endometriosis: A Randomized Controlled Trial
The goal of this investigator-initiated single-site clinical trial is to compare the overall quality of life of participants taking Relugolix combination therapy (Rel-CT) following excisional surgery for endometriosis to…
- Trial name
- NCT06439524
- Testing
- 40 mg relugolix, 1 mg estradiol, 0.5 mg norethindrone acetate
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Main Line Health
Overactive Bladder, Nocturia
NOGO for an Overactive Bladder
This is a double-blind, randomized and placebo-controlled study to evaluate the safety and effectiveness of NoGo, a standardized extract from Angelica archangelica, on overactive bladder
- Trial name
- NOGO-OAB (NCT04357223)
- Testing
- extract from Angelica archangelica leaf
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- SagaNatura
Kidney Stones, Ureteral Stones
The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients
To determine if emergency department patients with acute ureteral colic pain due to a ureteral stone who are treated with tamsulosin, versus placebo, will experience a shorter time to passage of their stone or resolution of their…
- Trial name
- NCT00448123
- Testing
- Tamsulosin
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Robert Swor
Hot Flashes
Study of Gabapentin Extended Release (G-ER)in the Treatment of Vasomotor (Hot Flashes/Hot Flushes) Symptoms in Postmenopausal Women.
Depomed's Gabapentin Extended Release is an investigational, extended release formulation of gabapentin that is being studied for the treatment of hot flashes in postmenopausal women
- Trial name
- NCT00777023
- Testing
- Gabapentin Extended-Release (G-ER) 1200 mg, Gabapentin Extended-Release (G-ER) 1800 mg
- Where
- 45 sites in United States
- Volunteers
- 565 people
- Sponsor
- Depomed
Venous Insufficiency
Antistax® in Patients With Chronic Venous Insufficiency
Study to determine the efficacy and tolerability of two dose levels of Antistax relative to placebo in patients suffering from CVI grade I or incipient grade II
- Trial name
- NCT02191280
- Testing
- Antistax®, low dose, Antistax®, high dose
- Volunteers
- 260 people
- Sponsor
- Boehringer Ingelheim
Endometriosis
SUPerficial ENDometriosis In Magnetic Resonance Imaging
The purpose of the study is to determine the correlation between the diagnosis of Superficial endometriosis by the 3DT1 sequence on Magnetic resonance imaging and the histology obtained by laparoscopy.
- Trial name
- SUPENDIM (NCT06195280)
- Testing
- Magnetic resonance imaging, 3DT1 sequence, Laparoscopy
- Where
- France
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Female Indoor Athletes
The Effects of Vitamin D Supplements on Sports Performance of Female Indoor Elite Athletes
This study is a randomized, double-blind study evaluated the effects of 90 days of vitamin D supplementation, with or without calcium, on bone mineral density and sports performance in indoor female semiprofessional athletes.
- Trial name
- RCT (NCT07748650)
- Testing
- Cholecalciferol (Vit D3), Calcium & Vitamine D3
- Where
- Taiwan
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University Hospital
Diastasis, Diastasis Recti
Diastasis Recti Abdominis and a Combined Treatment With Abdominal Exercise and Radiofrequency
Diastasis recti abdominis is a pathology that appears in a high percentage of women during the postpartum period. However, there is little evidence about its treatment.
- Conditions
- Diastasis, Diastasis Recti, Diastasis Recti and Weakness of the Linea Alba, Diastasis Recti Abdominis
- Trial name
- NCT06214650
- Testing
- Radiofrequency, Control
- Volunteers
- 44 people
- Sponsor
- University of Castilla-La Mancha
Abortion, Missed, Infertility Unexplained
Autologous Decidual-like Natural Killer Cells Therapy for Reproductive Failure
The aim of this study is to verify the efficacy of in vitro induction of autologous decidual-like NK cells therapy for reproductive failure associated with uterine NK cells abnormalities.
- Conditions
- Abortion, Missed, Infertility Unexplained, Reproductive Disorder
- Trial name
- NCT07230574
- Testing
- NK cell perfusion group
- Volunteers
- 159 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Breast Abnormalities
Use of Contrast Enhanced Spectral Mammography (CESM) for Women With Palpable Breast Abnormalities
Contrast Enhanced Spectral Mammography (CESM) is an advanced form of mammography which is performed after injection of contrast or dye into a vein in the arm. This dye is the same dye that is used for CT scans.
- Trial name
- NCT02406274
- Testing
- Contrast Enhanced Spectral Mammography (CESM)
- Where
- United States
- Volunteers
- 249 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Renal Insufficiency
A Study to Evaluate the Effect of Renal Impairment on JNJ-56136379 in Adult Participants
The purpose of this study is to evaluate the pharmacokinetics (PK) of a single oral dose of JNJ-56136379 in adult participants with renal impairment compared with healthy participants with normal renal function.
- Trial name
- NCT04474210
- Testing
- JNJ-56136379
- Where
- 2 sites in United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Malaria
Clinical Performance Evaluation of Fyodor Urine Malaria Test (UMT)
The purpose of this study is to evaluate the clinical performance of the one-step Fyodor Urine Malaria Test (UMT), to determine its accuracy (sensitivity and specificity) for the diagnosis of Plasmodium falciparum malaria in…
- Trial name
- NCT01921413
- Testing
- Urine Malaria Test
- Where
- Nigeria
- Volunteers
- 1,893 people, healthy volunteers welcome
- Sponsor
- Fyodor Biotechnologies Inc