Clinical trials: Fecal Microbiota Transplantation
Depression in Schizophrenia
FEcal Microbiota Transplantation
The primary objective will be to evaluate effectiveness, safety and acceptability of FMT on depressive symptoms at 2 months follow-up in SZ patients with resistant MD.
- Trial name
- NCT04001439
- Testing
- Experimental drug
- Volunteers
- 3,088 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Non-Alcoholic Fatty Liver Disease
Effects of Fecal Microbiota Transplantation on Weight in Obese Patients With Non-alcoholic Fatty Liver Disease
The worldwide impact of obesity suggests an urgent need for solutions to decrease its burden on modern society. It has been generally understood that obesity is caused by a simple imbalance in the intake of energy in the form of…
- Trial name
- NCT04594954
- Testing
- Diet, FMT, Physical Activity
- Where
- India
- Volunteers
- 110 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Clostridium Difficile Infection
FMT for Moderate to Severe CDI: A Randomised Study With Concurrent Stool Microbiota Assessment
Clostridium difficile infection (CDI) is a leading cause of hospital-associated gastrointestinal illness, associated with significant morbidity and mortality and has a high burden on health-care system.
- Trial name
- NCT02570477
- Testing
- Fecal Microbiota Transplantation, Vancomycin
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Chinese University of Hong Kong
Allogeneic Hematopoietic Cell Transplantation (HCT)
Fecal Microbiota Transplantation (FMT) in Recipients After Allogeneic Hematopoietic Cell Transplantation (HCT)
This research study is studying the role fecal microbiota transplantation may play in post-Hematopoietic Cell Transplantation (HCT) recipients
- Trial name
- NCT03720392
- Testing
- FMT
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Zachariah Michael DeFilipp
Clostridium Difficile Infection
Fecal Microbiota Transplantation for C Diff Infection
The objective of this study is to provide treatment with Fecal Microbiota Transplantation (FMT) to patients with recurrent or refractory Clostridium difficile infection (CDI).
- Trial name
- NCT01905709
- Testing
- Human fecal matter
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Englewood Hospital and Medical Center
Humoral Immunodeficiency, Hematopoietic Stem Cell Transplantation
Safety and Feasibility of FMT for Immune Recovery After HSCT
Patients who undergo allogeneic hematopoietic stem cell transplantation (allo-HSCT) often experience slow and incomplete recovery of their immune system, particularly the part responsible for producing antibodies (humoral…
- Trial name
- NCT07755319
- Testing
- Fecal microbiota transplantation (FMT)
- Where
- China
- Volunteers
- 86 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Chronic Insomnia Disorder
FMT for Insomnia Disorder (FMT-SLEEP)
Insomnia disorder is characterized by difficulty initiating or maintaining sleep, or early morning awakening accompanied by symptoms such as irritability or fatigue during wakefulness.
- Trial name
- NCT06606938
- Testing
- Faecal Microbiota Transplantation
- Where
- Hong Kong
- Volunteers
- 74 people
- Sponsor
- Chinese University of Hong Kong
Decompensated Cirrhosis
Fecal Microbiome Transplantation in Cirrhosis: Trial in Patients With Decompensated Cirrhosis
This is a phase III, multicenter, double-blind, placebo-controlled, randomized clinical trial to evaluate the safety and efficacy of Fecal Microbiota Transplantation (FMT) from healthy subjects to patients with decompensated…
- Trial name
- LiverGut (NCT06533852)
- Testing
- Fecal Microbiome Transplantation (FMT)
- Where
- 8 sites in Spain
- Volunteers
- 190 people
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
Fecal Microbiota Transplantation, Cesarean Section, Affecting Fetus or Newborn
Main Trial of the Cesarean Section and Intestinal Flora of the Newborn Study
In this study the investigators assess whether, in CS-delivered infants, the intestinal microbiome could be successfully and safely normalised by postnatal oral transfer of maternal fecal microbiome.
- Conditions
- Fecal Microbiota Transplantation, Cesarean Section, Affecting Fetus or Newborn, Intestinal Microbiome
- Trial name
- MT-SECFLOR (NCT04173208)
- Testing
- Fecal microbial transplant
- Where
- Finland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Autism Spectrum Disorder
WMT for Autism Spectrum Disorder (ASD)
Autism Spectrum Disorder (ASD) is a group of serious neurodevelopmental disorders. A significant comorbidity exists between ADHD and ASD: 30%-50% of individuals with ASD exhibit ADHD symptoms, and two-thirds with ADHD show ASD…
- Trial name
- NCT06030752
- Testing
- Washed Microbiota Transplantation
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Anorexia Nervosa
A Study on the Effects of Combined FMT on Gut Microbiota and Eating Disorder Symptoms in AN
The goal of this clinical trial is to determine if Fecal Microbiota Transplantation (FMT) is effective in treating Anorexia Nervosa (AN). The study will also explore how FMT works. The main questions it aims to answer are: 1.
- Trial name
- NCT06744751
- Testing
- Fecal Microbiota Transplantation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Mental Health Center
Carbapenemase-producing Enterobacteriaceae Infection
Clinical Trial to Demonstrate the Effectiveness of Fecal Microbiota Transplantation for Selective Intestinal Decolonization of Patients Colonized by Carbapenemase-producing Klebsiella Pneumoniae
Infections caused by carbapenemase-producing Enterobacteriaceae are frequent and often associated with high rates of mortality. Colonized patients are at increased risk of infection for these microorganisms.
- Trial name
- KAPEDIS (NCT04760665)
- Testing
- Fecal microbiota transplantation
- Where
- Spain
- Volunteers
- 2 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Ulcerative Colitis, Inflammatory Bowel Diseases
FMT for Remission of Active Ulcerative Colitis in Adults
The goal of this study is to establish the safety and effectiveness of lyophilized (LYO) fecal microbiota transplant (FMT) for treating ulcerative colitis (UC) in adults.
- Trial name
- NCT04202211
- Testing
- FMT oral, FMT enema
- Where
- 3 sites in Canada
- Sponsor
- University of British Columbia
Food Intolerance
Washed Microbiota Transplantation for Food Intolerance
Food intolerance (FI) is an adverse reaction to food caused by non-immune mechanisms, mainly related to digestive enzyme deficiencies (e.g. lactase deficiency), metabolic abnormalities (e.g.
- Trial name
- NCT07190183
- Testing
- washed microbiota transplantation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Clostridium Difficile
Rectal Bacteriotherapy, Fecal Microbiota Transplantation or Oral Vancomycin Treatment of Recurrent Clostridium Difficile Infections
The purpose of the study is to investigate if treatment with fecal microbiota transplantation or rectal bacteriotherapy is superior to standard vancomycin in patients with recurrent Clostridium Difficile infections.
- Trial name
- NCT02774382
- Testing
- Vancomycin, Fecal microbiota transplantation, Rectal bacteriotherapy
- Where
- 2 sites in Denmark
- Volunteers
- 450 people
- Sponsor
- Hvidovre University Hospital
Radiation Enteritis
CMTS0515-auWMT for Radiation Enteritis
This is a randomized controlled trial to explore the exploring the non-inferiority of CMTS0515-augmented WMT compared to WMT.
- Trial name
- NCT07331688
- Testing
- CMTS0515-augmented washed microbiota transplantation, Washed Microbiota Transplantation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Active Ulcerative Colitis
Superdonor FMT in Patients With Ulcerative Colitis
In the last decades fecal microbiota transplantation (FMT) has been established as a highly effective option in the treatment of recurrent Clostridioides difficile infection (rCDI), with a success rate of nearly 90%.
- Trial name
- NCT05739864
- Testing
- FMT
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Crohn Disease
Randomized Trial Comparing Single vs. Maintenance Fecal Microbiota Transplant for Refractory Crohn's Disease in Children
NCT02108821 Primary goal: -To determine the safety of fecal transplant by colonoscopy and retention enemas for induction followed by maintenance retention fecal vs.
- Trial name
- NCT03747718
- Testing
- Fecal Microbiota Transplantation
- Where
- United States
- Sponsor
- Stanford University
Localized Advanced Rectal Adenocarcinoma
Intestinal Microbiota Transplantation, Radiochemotherapy and Sintilimab in Localized Advanced Colon Cancer
The standard treatment for locally advanced rectal cancer is neoadjuvant chemoradiotherapy followed by total mesorectal excision.
- Trial name
- NCT06931808
- Testing
- Sintilimab plus Chemotherapy, Intestinal microbiota capsules, Standard Long Course Radiotherapy
- Where
- China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Ningbo University
Clostridioides Difficile Infection
Long-Term Outcomes After CDI: FMT Versus Antibiotic-Only Treatment
The goal of this observational study is to learn about the long-term effects of fecal microbiota transplantation (FMT) compared with antibiotic-only treatment in adults who were treated for Clostridioides difficile infection…
- Trial name
- LTO-CDI (NCT07569380)
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- Umeå University