Clinical trials: Feasibility Pilot Study
Risk Behavior, Cognitive Decline
Multidomain Intervention on Modifiable Lifestyle Risk Factors for Dementia Prevention
The overarching aim is to develop and deploy a multidomain intervention delivered on a mobile application to help middle-aged to older adults reduce their risk for dementia by improving a set of modifiable lifestyle risk factors…
- Trial name
- NCT05141578
- Testing
- Luci Coach Assisted Intervention
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- LuciLab
Hematopoietic and Lymphoid System Neoplasm, Lymphedema
Transcutaneous Sensors for the Detection of Cancer-Related Lymphedema, Project Limb Rescue Study
This clinical trial studies how well new adhesive-based sensors that stick to the skin (transcutaneous) work in detecting cancer-related long-term arm swelling (lymphedema).
- Conditions
- Hematopoietic and Lymphoid System Neoplasm, Lymphedema, Malignant Solid Neoplasm
- Trial name
- NCT06305884
- Testing
- Bioelectric Impedance Analysis, Exercise, Photoplethysmography
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cardiovascular Diseases, Type 2 Diabetes
HEART Kitchen Pilot
This study is testing a 28-day healthy eating program for adults who live in public housing and are at risk for heart disease. The program helps people eat more whole plant foods, like fruits, vegetables, beans, and whole grains…
- Conditions
- Cardiovascular Diseases, Type 2 Diabetes, Obesity and Obesity-related Medical Conditions
- Trial name
- HEARTKITCHEN (NCT07037121)
- Testing
- Whole Food Plant Based Diet Jumpstart
- Where
- United States
- Sponsor
- Reya Andrews
Multiple Myeloma, Heart Disease Risk Factors
MM-CARE: Cardiovascular Risk Assessment in Adults With Multiple Myeloma
People with multiple myeloma may have health conditions or receive treatments that increase their risk of heart and blood-vessel problems.
- Trial name
- MM-CARE (NCT07783607)
- Testing
- Oncology-Embedded Cardiovascular Risk Assessment Pathway, Primary Care Provider-Directed Cardiovascular Risk Assessment Pathway
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Vermont Medical Center
Head and Neck Neoplasms
Rehabilitation for Head and Neck Cancer
Patients treated for head and neck cancer (HNC) suffer from severe side-effects such as pain and difficulties in swallowing, often leading to weight loss.
- Trial name
- NCT02439892
- Testing
- Exercise and nutrition during radiotherapy, Multidimensional rehabilitation after radiotherapy
- Where
- 2 sites in Norway
- Volunteers
- 41 people
- Sponsor
- Norwegian University of Science and Technology
Acute Respiratory Distress Syndrome (ARDS), Acute Hypoxemic Respiratory Failure
Spontaneous vs Controlled Mechanical Ventilation in Acute Hypoxemic Respiratory Failure
Acute hypoxemic respiratory failure may progress to acute respiratory distress syndrome, a life-threatening condition that often requires mechanical ventilation.
- Trial name
- SVALBARD (NCT07463885)
- Testing
- Spontaneous Ventilation Strategy, Controlled Ventilation Strategy
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
ADHD - Attention Deficit Disorder With Hyperactivity
External Trigeminal Nerve Stimulation for Attention Deficit Hyperactivity Disorder - Feasibility Trial
The investigators will assess the use of the Monarch eTNS device as a non-pharmacological treatment for patients aged 7 to 17 years with ADHD. The investigators will compare the eTNS device to a sham device.
- Trial name
- eTNS4ADHD (NCT06655610)
- Testing
- External Trigeminal Nerve Stimulation
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
Osteoporosis
"Living an Active Life with Osteoporosis" - a Digital Patient Education Program on Osteoporosis. a Feasibility/pilot Study As Part of the PATOS Project (Patient Education in Osteoporosis).
In this feasibility and pilot study, the investigators aim to evaluate the effectiveness and safety of a digital patient education program for individuals with osteoporosis.
- Trial name
- PilotPATOS (NCT06729424)
- Testing
- Digital patient education program
- Where
- Sweden
- Volunteers
- 31 people
- Sponsor
- University Hospital, Linkoeping
Chronic Depressive Disorder
Development of a Telephone-based Continuation Treatment for Patients With Chronic Depression.
There is a high risk for relapse in people suffering from depression. Studies indicate that the continuation of an acute psychotherapeutic treatment can reduce the likelihood of relapse.
- Trial name
- NCT02397850
- Testing
- phone calls 30 min, phone calls 50 min
- Where
- Switzerland
- Volunteers
- 7 people
- Sponsor
- University of Zurich
Flying Phobia
An Internet-based Treatment for Flying Phobia
Flying phobia (FP) is one of the most prevalent phobias in our society. However, not all patients benefit from in vivo exposure, given that an important amount of them do not accept the intervention, drop out when they are…
- Trial name
- NCT03900559
- Testing
- NO-FEAR Airlines
- Where
- Spain
- Volunteers
- 78 people
- Sponsor
- Universitat Jaume I
Lower Extremity Fractures
Feasibility of Structured Resistance Training After Lower Extremity Fracture
Adults recovering from surgically managed diaphyseal femur or tibia fractures often experience persistent weakness, pain, and functional limitations despite successful fracture healing.
- Trial name
- NCT07629180
- Testing
- Structured Supervised Resistance Training and Coaching Program
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cystic Fibrosis, Respiratory Infection
Sputum Validation for the Molecular Diagnosis of Respiratory Viral Infections in Cystic Fibrosis
The aim of this pilot study is to demonstrate the feasibility of viral biomolecular diagnosis in sputum compared to nasopharyngeal swab in cystic fibrosis acute respiratory infection.
- Trial name
- EXPIRE (NCT03684759)
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Neuropathy;Peripheral
Exercise and Nutrition Interventions During Chemotherapy
This is a feasibility pilot study to initiate a research program to assess the effects of exercise on chemotherapy-induced peripheral neuropathy (numbness, tingling, and pain in the hands and feet).
- Trial name
- NCT03021174
- Testing
- EXCAP Exercise, Nutrition Education Control
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Rochester
Obesity
Prebariatric Surgery Physical Exercise Training in Telehealth
The aim of our study is to evaluate the feasibility of a supervised training session using telehealth in the "Clinique medico-chirurgicale du traitement de l'obésité de Sherbrooke" (CMCTO) and its impact on health, physical…
- Trial name
- TelePreSET (NCT02083913)
- Testing
- Telehealth supervised exercise training
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Université de Sherbrooke
Parents of Children With Cancer
The Effectiveness of Auricular Acupressure on Sleep Quality, Mood Status, and Quality of Life
This pilot study aimed to determine the feasibility and effectiveness of an auricular acupressure intervention on sleep, mood state, and QOL among parents of children with cancer.
- Trial name
- NCT05654155
- Testing
- auricular acupressure
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Chang Gung University of Science and Technology
Safety Issues, Feasibility
A Pilot Study of Deep Cervical Lymphatic-venous Anastomosis in the Treatment of Alzheimer's Disease
Alzheimer's disease (AD) is the most prevalent form of dementia, affecting 3-4% of the population over a lifetime. It's characterized by abnormal Amyloid-beta (Aβ) and tau protein expression and accumulation in the central…
- Conditions
- Safety Issues, Feasibility, Therapeutic Value
- Trial name
- NCT06448442
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Anorexia Nervosa, Bulimia
An App to Reduce Social Media's Impact on Body Image and Eating Disorders
Social media (SM) is a key communication tool, particularly for young women aged 15-29. While SM fosters social connections, it is also linked to negative effects on mental health, including poor body image, low self-esteem, and…
- Conditions
- Anorexia Nervosa, Bulimia, Body Dissatisfaction, Self-esteem
- Trial name
- BodyScreen (NCT06910410)
- Testing
- BodyScreen App
- Volunteers
- 50 people
- Sponsor
- Dalhousie University
Type 1 Diabetes Mellitus
Feasibility Study of a Portable Artificial Pancreas System in Type 1 Diabetes Mellitus (T1DM) - Montpellier
A single arm, single treatment study is proposed to assess the feasibility of a portable artificial pancreas system outside of a hospital based clinical research center.
- Trial name
- HomeCTR1_1 (NCT01447979)
- Testing
- portable artificial pancreas system with Control-To-Range algorithms
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University of Virginia
Liver Transplantation, Erythrocyte Transfusion
Blood Salvage From Liver Donors: a Feasibility Pilot Study
Blood recovery is a common procedure that limits patient exposure to allogeneic blood products. Blood recovery is usually performed during different types of surgery, including cardiac and vascular surgery, or liver…
- Trial name
- BLEED (NCT05835882)
- Testing
- Red Blood Cell concentrates from organ donor
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Breast Cancer, Body Weight Changes
Effects of a Paleolithic Lifestyle Intervention in Breast Cancer Patients Undergoing Radiotherapy
The study aims to test the feasibility and effects of a dietary and physical activity intervention based on evolutionary considerations in an oncological setting.
- Trial name
- NCT04574323
- Testing
- Curative radiotherapy, Paleolithic lifestyle intervention
- Where
- Germany
- Volunteers
- 13 people
- Sponsor
- MVZ Leopoldina GmbH