Clinical trials: Fatty Acids, Omega-3
Breast Cancer
Dietary Fat, Eicosanoids and Breast Cancer Risk
The primary objective of this investigation is to determine whether diets designed to increase plasma n3 concentrations (a low fat diet, with or without n3 fatty acid enrichment), will favorably affect sex hormone distribution in…
- Trial name
- NCT01824498
- Testing
- Low Fat diet, Low Fat high n3 diet, High Fat Diet
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Heart Failure
The Effects of a High Fat and Low Carbohydrate Diet on Clinical Status in Patients With Heart Failure
The aim of the present study was to evaluate the effects of a high fat, low carbohydrate (CHO) diet on clinical status during 60 days of follow-up in patients with stable heart failure (HF).
- Trial name
- NCT02150798
- Testing
- High fat and low carbohydrate diet, Control diet
- Where
- Mexico
- Volunteers
- 44 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Lung Cancer
Efficacy and Safety of Omega 3 Fatty Acid Supplements on Heavy Smokers
The study duration is 12 months. The initial enrollment visit will take approximately one hour. The Month 1, 3, 6, 7, 9 and 12 visits will take approximately 30 minutes each.
- Trial name
- Omega (NCT03936621)
- Testing
- Omega 3 fatty acid
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- British Columbia Cancer Agency
Healthy
Health Professional Dietary Habits and Blood Omega-3 Fatty Acid Concentrations
Health professionals attending the American Association for Family Physicians (AAFP) meeting at the Orlando Convention Center, Sept 21-23, 2016 who visit the DSM Nutritional Products Inc booth will be invited to complete an…
- Trial name
- NCT03056898
- Volunteers
- 387 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Depression
Omega-3 Fatty Acids for Treating Adults With Major Depression
This study will test the effectiveness of two different kinds of omega-3 fatty acid dietary supplements in treating the symptoms of major depression.
- Trial name
- NCT00517036
- Testing
- EPA omega-3 fatty acid, DHA omega-3 fatty acid
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- Cedars-Sinai Medical Center
COVID-19
Omega-3 Oil Use in COVID-19 Patients in Qatar
COVID-19 infection has been widely spread since December 2019 and causing many comorbidities and fatalities. The most common clinical presentation of COVID-19 patients admitted to ICUs is respiratory failure , hypoxia and acute…
- Trial name
- Omega3 (NCT04836052)
- Testing
- Omega 3 fatty acid
- Where
- Qatar
- Volunteers
- 372 people
- Sponsor
- Hamad Medical Corporation
Healthy Volunteers, Markers of Cardiovascular Risk
Efficacy Study of Stearidonic Acid (SDA) Soybean Oil-containing Foods on Red Blood Cell Fatty Acid Content
The purpose of this clinical trial is to evaluate whether the omega-3 fatty acid stearidonic acid (SDA), when used as a food ingredient, increases the level of the long-chain omega-3 fatty acid eicosapentaenoic acid (EPA) in red…
- Trial name
- NCT01369550
- Testing
- SDA soybean oil-containing foods, High-oleic sunflower oil containing foods, Eicosapentaenoic acid
- Where
- 2 sites in United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Monsanto Company, LLC
HIV/AIDS
Effect of Omega 3 Fatty Acids on Oxidative Stress in HIV Seropositive Patients
Introduction: Highly active antiretroviral therapy (HAART) has showed its effectiveness in the prevention of complications in seropositive for HIV patients.
- Trial name
- NCT02041520
- Testing
- omega 3 fatty acids
- Where
- Mexico
- Volunteers
- 70 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Healthy
Pharmacokinetics of Omega-3 Monoglycerides
North American diets have insufficient omega-3 fatty acid (n-3 FA) content. Consequently, they display low plasma concentrations of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), the two main long chain n-3 FA.
- Trial name
- NCT04382027
- Testing
- Omega-3 + vitamin K2 (monoacylglycerol form), Omega-3 + vitamin K2 (ethyl ester)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Pregnancy
N-3 Fatty Acid Requirements for Human Development
Polyunsaturated fatty acids known as n-3 fatty acids are essential dietary nutrients for humans, and are known to be important to reducing the risk of certain diseases, particularly those related to neural system, cardiovascular…
- Trial name
- NCT00620672
- Testing
- omega 3 fatty acids, vegetable oil
- Where
- Canada
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Dry Eye
An Observational Study to Assess Optive MEGA-3 (OM3) on Dry Eye Symptoms and Quality of Life of Adult Participants With Mild to Moderate Dry Eye Disease (DED)
Dry Eye Disease (DED) is a condition where the tear film of the eye becomes unstable and along with ocular surface inflammation and damage leads to inadequate tear production and eye lubrication.
- Trial name
- NCT06439394
- Testing
- Optive MEGA-3 (OM3)
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- AbbVie
Adenocarcinoma of the Prostate, Stage I Prostate Cancer
Low-Fat Diet and Fish Oil in Men on Active Surveillance for Prostate Cancer
This randomized phase II trial will evaluate if a low omega-6, high omega-3 fat diet combined with fish oil has the potential to delay disease progression in patients with prostate cancer undergoing active surveillance.
- Conditions
- Adenocarcinoma of the Prostate, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
- Trial name
- NCT02176902
- Testing
- behavioral dietary intervention, omega-3 fatty acid, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Aging
Effects of Vitamin D and Omega-3 Supplementation on Telomeres in VITAL
The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) was a randomized clinical trial in 25,871 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or fish oil (1 gram of omega-3…
- Trial name
- NCT04386577
- Testing
- Vitamin D3 (cholecalciferol), fish oil
- Where
- United States
- Volunteers
- 1,054 people, healthy volunteers welcome
- Sponsor
- Augusta University
Colon Cancer
Effect of Omega-3 Fatty Acids on the Perioperative Immune Response and Erythrocyte Function
Ideally, the postoperative inflammatory response is part of a well-orchestrated mechanism that contributes to tissue healing and rapid recovery.
- Trial name
- EMPIRE (NCT02231203)
- Testing
- Omegaven
- Where
- Netherlands
- Volunteers
- 44 people
- Sponsor
- Medical Center Alkmaar
Heart Failure Congestive
Effect of omega3 on Congestive Heart Failure
In this double blinded study patients with resynchronization pacemaker- AICD were assigned to Omega3 and placebo randomly, results indicated that Omega3 had no more effect than placebo in mortality, BNP level and 6 minutes walk…
- Trial name
- NCT01227837
- Testing
- omga3
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Shiraz University of Medical Sciences
Arthralgia, Breast Neoplasms
Omega-3 Supplementation in Prevention of Aromatase Inhibitor-Induced Toxicity in Patients With Stage I-III Breast Cancer
This clinical trial studies the use of omega-3 fatty acid supplementation in preventing aromatase inhibitor-induced toxicity in patients with stage I-III breast cancer.
- Trial name
- NCT02831582
- Testing
- Omega-3 Fatty Acid
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Attention Deficit Hyperactivity Disorder, Healthy
The Effects of EPA/DHA Supplementation on Cognitive Control in Children With ADHD
Forty children with and 40 children without Attention deficit Hyperactivity Disorder (ADHD) receive Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA) or placebo via a dietary intervention.
- Trial name
- NCT01554462
- Testing
- Eicosapentaenoic acid / Docosahexaenoic acid
- Where
- Netherlands
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Atherosclerosis Cardiovascular Disease
Effect of Icosapent-ethyl Ester (IPE) to Reduce the Residual Risk Cardiovascular Disease.
Cardiovascular diseases (CVDs) are the leading cause of global mortality, despite significant advances in prevention and treatment.
- Trial name
- NCT06720662
- Testing
- Icosapent-ethyl ester capsules, Corn oil Control
- Volunteers
- 294 people
- Sponsor
- University of Sao Paulo
Severe Hypertriglyceridemia
Epanova® for Lowering Very High Triglycerides
The primary objective of the study is to determine the efficacy of Epanova (omefas) compared to placebo in lowering serum triglycerides in subjects with severe hypertriglyceridemia.
- Trial name
- EVOLVE (NCT01242527)
- Testing
- omefas
- Where
- 68 sites in United States, Denmark and 5 more
- Volunteers
- 399 people
- Sponsor
- AstraZeneca
Healthy
The Combination Effect of Citicoline and Omega-3
The goal of this study is to determine the effects of Citicoline plus Omega-3 or Omega-3 alone versus placebo on attention in non-demented healthy older adults.
- Trial name
- NCT03444662
- Testing
- Citicoline and Omega-3 supplement, Omega-3 supplement
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kyowa Hakko Bio Co., Ltd.