Clinical trials: Fatigue Symptom
Endometrial Clear Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma
Pelvic Radiation Therapy or Vaginal Implant Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With High-Risk Stage I or Stage II Endometrial Cancer
This randomized phase III trial studies pelvic radiation therapy to see how well it works compared with vaginal implant radiation therapy, paclitaxel, and carboplatin in treating patients with high-risk stage I or stage II…
- Conditions
- Endometrial Clear Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma, Fatigue, Neurotoxicity Syndrome
- Trial name
- NCT00807768
- Testing
- 3-Dimensional Conformal Radiation Therapy, Carboplatin, Intensity-Modulated Radiation Therapy
- Where
- 540 sites in United States, South Korea
- Volunteers
- 601 people
- Sponsor
- Gynecologic Oncology Group
Anxiety Disorder, Cognitive/Functional Effects
Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer
RATIONALE: Participating in a physical activity program designed to increase free time physical activity and receiving written health education materials may influence the chance of cancer recurring as well as impact on physical…
- Conditions
- Anxiety Disorder, Cognitive/Functional Effects, Colorectal Cancer, Depression
- Trial name
- CHALLENGE (NCT00819208)
- Testing
- exercise intervention, counseling intervention, educational intervention
- Where
- 47 sites in United States, Australia and 4 more
- Volunteers
- 889 people
- Sponsor
- Canadian Cancer Trials Group
Multiple Sclerosis, Fatigue
Aspirin for Treatment of Multiple Sclerosis-Related Fatigue
The purpose of this study is to determine whether aspirin is effective for treatment of fatigue caused by multiple sclerosis (MS).
- Trial name
- NCT00467584
- Testing
- High Dose Aspirin (1300 mg/day), Low Dose Aspirin (162 mg/day)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Mayo Clinic
Mental Fatigue
Mindfulness, Mental Fatigue, Inhibitory Control and Endurance Performance in Athletes
This study investigated whether trait mindfulness in athletes is associated with impairments in neurocognitive function and endurance performance resulting from mental fatigue.
- Trial name
- NCT05466136
- Testing
- Mental fatigue condition, Control condition
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
HIV Infections, Fatigue
Effectiveness of Armodafinil for Treating Fatigue in Adults With HIV/AIDS
This study will determine whether armodafinil (Nuvigil), an FDA approved medication, is effective in reducing fatigue in adults with HIV/AIDS.
- Trial name
- NCT00737204
- Testing
- Armodafinil
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- New York State Psychiatric Institute
Chronic Fatigue Syndrome
Use of Sildenafil (Viagra) to Alter Fatigue, Functional Status and Impaired Cerebral Blood Flow in Patients With CFS
Use of Viagra to Alter Symptoms in Patients with Chronic Fatigue Syndrome (CFS)
- Trial name
- NCT00598585
- Testing
- Sildenafil (Viagra)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Cardiac Failure, Heart Failure
Insomnia Self-Management in Heart Failure
Chronic insomnia may contribute to the development and exacerbation of heart failure (HF), incident mortality and contributes to common and disabling symptoms (fatigue, dyspnea, anxiety, depression, excessive daytime sleepiness…
- Conditions
- Cardiac Failure, Heart Failure, Congestive Heart Failure, Heart Failure, Congestive
- Trial name
- HSS (NCT02660385)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Self-Management Education for Heart Failure
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Yale University
Invasive Breast Cancer (Stage I-III), Ductal Carcinoma in Situ
Naltrexone RCT for Treatment-Emergent Fatigue in Patients Receiving Radiation Therapy for Breast Cancer
Naltrexone is a drug which blocks some effects of chemicals called beta-endorphins that are made in the body. Beta-endorphins can be made in response to stress, injury, and also pleasurable activities.
- Conditions
- Invasive Breast Cancer (Stage I-III), Ductal Carcinoma in Situ, Lobular Carcinoma in Situ, Lobular Carcinoma
- Trial name
- NCT02137252
- Testing
- Naltrexone, Sugar Pill
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Dana-Farber Cancer Institute
Major Depressive Disorder
Omega-3 Fatty Acids as Adjunct Treatment for Major Depressive Disorder
The primary objective of the study was to determine the effects of 10-week adjunctive supplementation with 2 doses of LCn-3 fatty acids (fish oil) on cortical functional activity and biochemistry in adolescents with MDD.
- Trial name
- NCT00511810
- Testing
- Low Dose Fish Oil, High Dose Fish Oil
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Cincinnati
Fatigue, Aging
Mechanisms to Reduce Mental and Physical Fatigue Following Exercise Training in Older Adults
Fatigue is a strong predictor of negative health outcomes in older adults. The research in this study will compared the effects of 8-weeks of branched chain amino acids (BCAAs: dietary supplements commonly taken to improve muscle…
- Trial name
- BCAA (NCT05484661)
- Testing
- BCAA
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
High Altitude Pulmonary Hypertension
The Safety Evaluation of Aminophylline and Ambrisentan When Administered Orally Alone and in Combination to Healthy Volunteers
This is a Phase I, three period, two sequence, open-label, randomized, crossover study, with the primary objective of testing the safety and tolerability of combined oral doses of aminophylline and ambrisentan in healthy human…
- Trial name
- GQ01 (NCT01530464)
- Testing
- Aminophylline, Ambrisentan, Aminophylline plus ambrisentan
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Thies Schroeder
Chronic Pain, Fibromyalgia
Developing an Activity Pacing Framework: Feasibility and Acceptability
This study explores whether it is feasible to use a newly developed activity pacing framework to standardise how activity pacing is instructed by healthcare professionals in rehabilitation programmes for patients with chronic…
- Conditions
- Chronic Pain, Fibromyalgia, Chronic Fatigue Syndrome, Chronic Low Back Pain
- Trial name
- NCT03497585
- Testing
- Activity pacing framework
- Where
- United Kingdom
- Volunteers
- 112 people
- Sponsor
- Pennine Acute Hospitals NHS Trust
Fatigue, Ovarian Cancer
Acupressure for Fatigue in Ovarian Cancer Survivors
The purpose of this study is to see if accupressure can help reduce the severity of fatigue experienced by ovarian cancer patients.
- Trial name
- NCT03763838
- Testing
- Acupressure, Standard of Care
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- University of Michigan Rogel Cancer Center
Multiple Sclerosis
tDCS to Lower Neuropathic Pain and Fatigue in People With Multiple Sclerosis
The purpose of this study is to investigate the effects of transcranial direct current stimulation (tDCS) on neuropathic pain and fatigue in people with MS. The investigators will conduct tDCS or sham on 5 consecutive days.
- Trial name
- NCT03870048
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Iowa
Fatigue, Sleep Disturbance
Feasibility of Bright Light Therapy on Fatigue, Sleep and Circadian Activity Rhythms in Lung Cancer Survivors
The purpose of this study is to determine the feasibility of a morning bright light therapy intervention for fatigue, sleep disturbances, and circadian activity rhythms in lung cancer survivors.
- Conditions
- Fatigue, Sleep Disturbance, Circadian Dysregulation
- Trial name
- NCT02954809
- Testing
- Morning bright light therapy, Dim light
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- State University of New York at Buffalo
Multiple Sclerosis
Can Transcranial Direct Current Stimulation Improve Ambulation and Fatigue Resistance in People With MS?
In this project the investigators will be using non-invasive brain stimulation on people with multiple sclerosis (PwMS) to improve leg muscle function. Two groups of participants will be recruited.
- Trial name
- NCT02987621
- Testing
- tDCS
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Colorado State University
Traumatic Brain Injury
Recombinant Human Growth Hormone During Rehabilitation From Traumatic Brain Injury.
Growth Hormone (GH) deficiency, defined by insufficient GH response to a variety of stimulating compounds, is found in 20-35% of adults who suffer traumatic brain injuries (TBI) requiring inpatient rehabilitation1.
- Trial name
- Growth-TBI (NCT00766038)
- Testing
- Recombinant human Growth Hormone
- Where
- 3 sites in United States
- Volunteers
- 63 people
- Sponsor
- University of Pennsylvania
Cancer Related Fatigue
Body Mind Training Project
Aim 1: Assess the feasibility, safety and efficacy of a Qigong intervention in elderly prostate cancer survivors. Describe participation, retention, and adherence rates and assess reasons for participation, attrition, and…
- Trial name
- NCT01564394
- Testing
- Qigong, Non-aerobic stretching
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Utah
Hemodialysis, Fatigue
Electrical Muscle Stimulation Versus Resistive Training On Physical Measures, And Fatigue In Hemodialysis Patients
The purpose of this randomized controlled trial is to compare the effects of intradialytic neuromuscular electrical stimulation (NMES) and intradialytic resistance exercise with usual care on physical function, dialysis adequacy…
- Trial name
- NCT06079502
- Testing
- Neuromuscular Electrical Stimulation, resistive training program, usual care dialysis
- Where
- 2 sites in Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Multiple Sclerosis
A Randomized Trial of Two Formal Group Programs for Multiple Sclerosis
The purpose of this study is to compare two different educational programs for people with multiple sclerosis (MS), which is a common and often disabling disease of the central nervous system.
- Trial name
- NCT01918800
- Testing
- Fatigue: Take control, MS: Take Control
- Where
- 4 sites in United States
- Volunteers
- 282 people
- Sponsor
- VA Office of Research and Development