Clinical trials: Fasting
Pulmonary Arterial Hypertension
Effect of BIA 5-1058 400 mg on the Steady State Pharmacokinetics of Sildenafil
The purpose of this study is: To assess the effect of BIA 5 1058 400 mg on the pharmacokinetics (PK) of sildenafil. To assess the effect of sildenafil on the PK of BIA 5-1058.
- Trial name
- NCT04994860
- Testing
- BIA 5-1058, Sildenafil
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Pulmonary Complication
Perioperative Lung Ultrasonography for Fast-track Cardiac Surgery
The investigators evaluate the usefulness of lung ultrasonography in the perioperative period for postoperative outcomes in children undergoing fast track cardiac surgery.
- Trial name
- NCT03527862
- Testing
- Treatment according to lung ultrasonography
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Seoul National University Hospital
Gastric or Duodenal Ulcers
A Study to Evaluate the Pharmacokinetics and Safety Between Single Administration of "BR6002" and Coadministration of "BR6002A" and "BR6002B" Under Fasting Conditions in Healthy Adult Volunteers
The purpose of this clinical trial is to evaluate the pharmacokinetics and safety between single administration of "BR6002" and coadministration of "BR6002A" and "BR6002B" under fasting conditions in healthy adult volunteers
- Trial name
- NCT05959486
- Testing
- BR6002A, BR6002B, BR6002
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Obesity
Fast Food Photo Study
The investigators aim to discover if people of different demographic levels are more or less attentive to changes in calorie information vs. changes in price information on a restaurant menu.
- Trial name
- NCT02267954
- Testing
- Menu edited
- Where
- 2 sites in United States
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Aspiration; Liquids, Fasting
Gastric Emptying of Maltodextrin Solution in Elderly and in Adults
Gastric volume will be measured before, 5, 30, 60, 90 and 120 min after drinking 450ml of maltodextrin in young adults and elderly.
- Conditions
- Aspiration; Liquids, Fasting, Perioperative Pulmonary Aspiration
- Trial name
- GEMA (NCT04288466)
- Testing
- maltodextrin
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brasilia University Hospital
Gastritis
A Pilot Study to Determine the Relative Bioavailability of Mosapride 5mg From Two Candidate Formulations of GR107719B Relative to One 5mg Tablet of Reference Mosapride Citrate (GASMOTIN™) in Healthy Adult Human Subjects Under Fasting Conditions
This study aims to determine the relative bioavailability of two candidate formulations of mosapride citrate 5mg tablets compared the reference product GASMOTIN (mosapride citrate 5mg) from Dainippon Pharmaceutical Company in…
- Trial name
- NCT02201316
- Testing
- Reference mosapride citrate (GASMOTIN), GR107719B (Formulation 1), GR107719B (Formulation 2)
- Where
- India
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dyslipidemia, Hypercholesterolemia
A Study to Evaluate Fasting/Postprandial Serum Apolipoprotein B-48 (ApoB-48) Levels in Diabetic Participants With Normal to Moderately High Low Density Lipoprotein-C (LDL-C) Levels (MK-0653A-259 AM1)
This study will evaluate whether fasting/postprandial serum ApoB-48 levels are increased in diabetic participants compared to nondiabetic participants with the same range of serum LDL-C levels, and whether ApoB-48 levels can be…
- Trial name
- NCT01333436
- Testing
- Test Meal
- Where
- South Korea
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Covid19
The Salivary Raman COVID-19 Fingerprint
The outbreak of coronavirus disease 2019 (COVID-19), caused by infection of SARS-CoV-2, has rapidly spread to become a worldwide pandemic.
- Trial name
- NCT04583306
- Testing
- Raman analysis of saliva, characterization of the Raman database and building of the classification model
- Where
- 5 sites in Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Asthma, Heart Rate Fast
Acute Effect of Salbutamol on Heart Rate and Blood Pressure During Exercise in Patients With Moderate or Severe Asthma and Healthy Subjects
Contextualization: Exercise is a common triggers of bronchospasm in patients with asthma and healthy subjects. To prevent these symptoms frequently they have to use Short-Acting Beta2-Agonists.
- Trial name
- NCT03044938
- Testing
- salbutamol
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universidade Ibirapuera
Healthy
Fasting Study of Fexofenadine Tablets 180 mg and Allegra® Tablets 180 mg
The objective of this study was to investigate the bioequivalence of Mylan's fexofenadine 180 mg tablets to Aventis' Allegra® 180 mg tablets following a single, oral 180 mg (1 x 180 mg) dose administered under fasting conditions.
- Trial name
- NCT00649376
- Testing
- Fexofenadine Tablets 180 mg, Allegra® Tablets 180 mg
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Hypertension, Chronic Stable Angina
Bioequivalency Study of Amlodipine Tablets Under Fasting Conditions
The objective of this study was the bioequivalence of a Roxane Laboratories' Amlodipine Besylate tablets, 10 mg, to Norvasc® Tablets, 10 mg (Pfizer) under fasting conditions using a single-dose, randomized, 2-treatment, 2-period…
- Conditions
- Hypertension, Chronic Stable Angina, Vasospastic Angina
- Trial name
- NCT00602017
- Testing
- Amlodipine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Arrhythmias, Cardiac
Artificial Intelligence (AI) Enabled, Cloud-based ECG Diagnostic Solution (ZBPro) Feasibility Testing
The proposed research is to address the accessibility and affordability of technology to capture symptomatic and asymptomatic cardiac events via Long-Term Continuous Electrocardiogram Monitoring (LTCM), and to provide physicians…
- Trial name
- NCT06013917
- Testing
- Cardiac Monitoring
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- ZBeats INC
Pharmacokinetics, Epinephrine
Study of Drug Exposure in Systemic Circulation of Primatene Mist by Oral Inhalation, Versus Epinephrine Injection by Intramuscular Injection and ProAir by Oral Inhalation in Healthy Individuals
To assess the drug exposure profile in systemic circulation of Primatene Mist by inhalation, versus Epinephrine by intramuscular injection, and ProAir HFA by inhalation in healthy adults.
- Conditions
- Pharmacokinetics, Epinephrine, Albuterol, Asthma
- Trial name
- NCT04207840
- Testing
- Epinephrine (0.125 mg/inhalation), Epinephrine Injection Auto-Injector (0.3mg/0.3mL), Albuterol Sulfate (0.09 mg/inhalation)
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Obesity, Meal Frequency
Time Restricted Eating and Meal Frequency for Appetite Control
Obesity is one of the largest worldwide health problems. There are increasing rates of overweight and obesity, and in recent years, worldwide the percentage of overweight and obesity among adults now exceeds 1.9 billion and 650…
- Conditions
- Obesity, Meal Frequency, Appetite, Body Composition
- Trial name
- TRE (NCT07805291)
- Testing
- MT1, MT2
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Intermittent Fasting
The Immun Status Changes Due to Intermittent Fasting
Positive effects of calorie restriction on quality of life and diseases are reported. Intermittent fasting, one of the calorie restriction methods, has been shown to be beneficial for health with many metabolic effects, not just…
- Trial name
- NCT04877314
- Testing
- Intermittent fasting
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Healthy
Topiramate 25 mg Tablets Under Fasting Conditions
The objective of this study was to compare the rate and extent of absorption of topiramate 25 mg tablets (test) versus Topamax® (reference) administered as 2 x 25 mg tablets under fasting conditions.
- Trial name
- NCT00905606
- Testing
- Topiramate Tablets, Topamax® Tablets
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
Complication of Surgical and Medical Care.
Enhanced Recovery After Surgery in Major Intrabdominal Procedures.
Enhanced Recovery After Surgery (ERAS) programs have been introduced with aims of attenuating the stress response to surgery and enabling rapid recovery.
- Trial name
- NCT01400711
- Testing
- ERAS perioperative care, Traditional
- Where
- Greece
- Volunteers
- 54 people
- Sponsor
- St. Andrew's General Hospital, Patras, Greece
Elective Cesarean Delivery, Fasting ( 6H for Solid ; 2H for Clear Fluid )
Carbohydrate Loading Fasting Protocol Versus 'Sip Til Send'
Women undergoing elective caesarean deliveries are fasted for long periods prior to surgery. Recently, Rotunda Maternity Hospital have started using two fasting protocols at the Rotunda prior to elective caesarean section, one…
- Trial name
- NCT06505915
- Testing
- Pre op Carbohydrate drink, Clear fluid as per sip til send policy
- Where
- Ireland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Rotunda Hospital
Healthy
Study Of The PF-04958242 Blood Concentrations Of A Capsule Formulation Of PF-04958242 Compared To A Solution Formulation
This study will assess the relative bioavailability of a capsule formulation of PF-04958242, relative to a oral solution formulation of PF-04958242 in healthy adult subjects.
- Trial name
- NCT01646840
- Testing
- PF-04958242 capsule, PF-04958242 oral solution
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Biogen
Healthy
Lamotrigine 25 mg Chewable Tablets, Non-Fasting
The objective of this study is to compare the rate and extent of absorption of lamotrigine 25 mg chewable dispersible tablets (test) versus Lamictal® (reference) administered as 2 x 25 mg chewable dispersible tablets under fed…
- Trial name
- NCT00838136
- Testing
- Lamotrigine 25 mg Chewable Tablets, Lamictal® 25 mg Chewable Tablets
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA