Clinical trials: Farsightedness
Myopia, Hyperopia
Evaluation of Effectiveness of Correcting Refractive Error With Ready-made Spectacles
This research project will compare two methods of correcting refractive error (long or short-sightedness) with spectacle lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- RECS (NCT00657670)
- Testing
- Ready-made spectacles, Spectacles
- Where
- 2 sites in China, India
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Ocular Surface Disease, Irregular Astigmatism
Evaluation of the Safety and Efficacy of Rigid Breathable Scleral Contact Lenses for the Correction of Ametropia
To evaluate the short-term efficacy and safety of scleral contact lens in the clinical treatment of patients with irregular astigmatism after corneal transplantation by analyzing ocular parameters and ocular surface conditions of…
- Conditions
- Ocular Surface Disease, Irregular Astigmatism, Contact Lens Complication, Corneal Astigmatism
- Trial name
- NCT06256770
- Where
- China
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Hyperopic Presbyopia
Prospective Investigation of SUPRACOR Visual Outcomes of Presbyopic Hyperopic Patients With and Without Astigmatism
This phase IV study is an open, prospective, single-center, single-surgeon bilateral eye study to investigate the bilateral uncorrected intermediate visual acuity of presbyopic hyperopic patients, who have been treated with…
- Trial name
- NCT01628146
- Testing
- SUPRACOR LASIK treatment
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technolas Perfect Vision GmbH
Refractive Error - Myopia Axial, Astigmatism
Refractive Accuracy of "2WIN" and Portable Autorefractors
Youth and some adults have photoscreening refractions and hand-held auto refraction before cycloplegia refraction during new and follow up eye examinations.
- Conditions
- Refractive Error - Myopia Axial, Astigmatism, Accomodation, Visual Impairment
- Trial name
- NCT04249505
- Testing
- "2WIN" Photoscreener, "Plusoptix A12", "Retinomax"
- Where
- United States
- Volunteers
- 708 people, healthy volunteers welcome
- Sponsor
- Alaska Blind Child Discovery
Refractive Errors
Study to Evaluate the Safety and Efficacy of HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens
Study to evaluate the safety and efficacy of HI-BRITE large diameter rigid gas permeable contact lens (hexafocon b) test when worn on a daily wear basis in the correction of myopia/hyperopia/astigmatism/presbyopia/ and irregular…
- Trial name
- NCT02812316
- Testing
- HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens
- Where
- Taiwan
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Hospital
Myopia, Hyperopia
Time Course Comparison of Contact Lens Maintenance Systems for Hydrogel Lenses
The principal aim of this project is to determine the time course of development of contact lens and contact lens case contamination during daily wear of silicone hydrogel lenses.
- Trial name
- NCT00732004
- Testing
- Silicone Hydrogel Contact Lenses, 1x PMBH preserved MPS, 1x Polyquad/Aldox MPS
- Where
- Australia
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Myopia, Hyperopia
Evaluation of Silicone Hydrogel Daily Wear Contact Lenses for Up to One (1) Month of Daily Wear
The aim of the study is to evaluate if the performance of Invigor A is substantially equivalent to Invigor B contact lenses when used in a one month recommended replacement, daily wear modality.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT03722784
- Testing
- Invigor A (test), Invigor B (control)
- Where
- 6 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cycloplegia
Cycloplegic Refraction Among Children
The primary outcome of this study is to compare cyclopentolate 1% and tropicamide 1% for cycloplegic refractions in pediatric populations.
- Trial name
- NCT05442801
- Testing
- Cyclopentolate, Tropicamide
- Where
- Jordan
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Islamic Hospital, Jordan
Emmetropization, Myopia
Focus-out Glasses on Emmetropization in Chinese Children
The purpose of this study is to characterize the effects of peripheral focous-out glasses on emmetropization in non-myopic Chinese Children Aged 6-8 Years.This is a prospective, parallel-controlled randomized trial.
- Conditions
- Emmetropization, Myopia, Hyperopia
- Trial name
- NCT05689567
- Testing
- DEFOG glasses(peripheral focus-out glasses)
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Myopia, Hyperopia
Comparing Low-cost Handheld Autorefractors - a Practical Approach to Measuring Refraction in Low Resource Settings
Study compares four portable vision measurement and eye-imaging technologies in terms of accuracy and time and ease of use with older adult (ages 40-100) participants in a developing-country setting (India).
- Trial name
- NCT03456245
- Testing
- Vision device validation
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Myopia, Hyperopia
A Clinical Evaluation of a Phakic Intraocular Lens
The objective of this study is to evaluate the clinical performance of the STAAR EVO+ Visian™ Implantable Collamer® Lens with Aspheric (EDOF) Optic as refractive elements to correct or reduce myopia or hyperopia with presbyopia…
- Conditions
- Myopia, Hyperopia, Astigmatism, Presbyopia
- Trial name
- NCT07291739
- Testing
- Implantable Collamer Lens (ICL)
- Where
- Philippines
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Staar Surgical Company
Myopia, Hyperopia
Comparison of Acular LS Versus Nevanac for Pain Control in Eyes Undergoing PRK
To determine the ability of two topical Nonsteroidal Anti-inflammatory drops (Acular LS \& Nevanac) to help control pain following Photorefractive Keratectomy (PRK).
- Trial name
- NCT00347204
- Testing
- ketorolac (Acular LS), Nepafenac (Nevanac)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Center For Excellence In Eye Care
Keratomileusis, Laser In Situ
The Role of Psychosocial and Other Quality of Life Parameters in Evaluating Functional Changes Prior to and Following Laser In-situ Keratomileusis (LASIK)Changes Laser In-situ Keratomileusis (LASIK)
To evaluate the changes in quality of life parameters after LASIK surgery.
- Trial name
- NCT00344604
- Testing
- Role of psychosocial and quality of life parameters prior to and following LASIK.
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Presbyopia
Bifocal Contact Lens Study for Adults With Age-Related Near Vision Loss
The primary objective of this study is to evaluate the distance, intermediate and near visual performance of Clerio designed single vision and Clerio designed LIRIC modified bifocal lenses (+2.00D add) compared to commercially…
- Trial name
- NCT03653715
- Testing
- Clerio Vision LIRIC-modified Bifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Multifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Contact Lens
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Clerio Vision, Inc.
Myopia, Hyperopia
Clinical Evaluation of Two Frequent Replacement Soft Spherical Contact Lenses
This was a single-blind (participant masked), interventional, prospective, direct refit, bilateral wear short-term fitting study.
- Trial name
- NCT05656885
- Testing
- Lens A, Lens B
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Healthy, Myopia
Ocular Imaging With Spectral Domain Optical Coherence Tomography
The purpose of this study is to analyze macular retinal thickness and macular volume using the spectral domain - optical coherence tomography (SD-OCT) in normal eyes and in eyes with various ocular diseases.
- Conditions
- Healthy, Myopia, Hypermetropia
- Trial name
- NCT00926549
- Testing
- Spectral domain-OCT (Cirrus™ HD-OCT, Carl Zeiss Meditec AG)
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Myopia,, Hyperopia,
Refraction Determination Analysis
Correlating the accuracy of a refraction done over telemedicine to that of a standard refraction, with a study hypothesis that the results will be equivalent.
- Conditions
- Myopia,, Hyperopia,, Astigmatism,, Presbyopia,
- Trial name
- NCT01995435
- Testing
- Telemedicine refraction, Traditional refraction
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lee, Steven, M.D.
Myopia, Hyperopia
APIOC Sphere and APIOC Astigmatism
Vision and comfort, both objective and subjective, will be assessed for single vision contact lens wearers for either the APIOC™ Sphere or the APIOC™ Astigmatism contact lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT04806802
- Testing
- APIOC Sphere and APIOC Astigmatism
- Where
- 6 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lentechs, LLC
Hyperopia, Myopia
A Comparison of Fellow Eyes Undergoing LASIK or PRK With a Wavefront-guided Excimer Laser Versus a Wavefront-optimized Excimer Laser
Subjects with myopia, hyperopia and astigmatism are being randomized to be treated in one eye with a wavefront-guided excimer laser and their fellow eye treated with a wavefront-optimized excimer laser.
- Conditions
- Hyperopia, Myopia, Astigmatism
- Trial name
- NCT01135719
- Testing
- LASIK and PRK
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Edward E. Manche
Myopia, Astigmatism
Randomized, Non-inferiority Trial Comparing SMILE and LASIK
Background: Small Incision Lenticule Extraction or SMILE is a novel form of 'flapless' corneal refractive surgery that was adapted from Refractive Lenticule Extraction (ReLEx).
- Conditions
- Myopia, Astigmatism, Hypermetropia
- Trial name
- NCT01216475
- Testing
- Femtosecond LASIK, Small incision lenticule extraction (SMILE)
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre