Clinical trials: Family Members
Huntington Disease
Cooperative Huntington's Observational Research Trial
The purpose of this study is to collect prospective data from individuals who are part of a Huntington Disease (HD) family, in order to relate phenotypes between individuals and families with each other and genetic factors in…
- Trial name
- NCT00313495
- Where
- 52 sites in United States, Australia and 1 more
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- HP Therapeutics Foundation
Liver Disease
Heritability of Fatty Liver as Measured by MRI: a Cross Sectional Study of Twins and Family Members
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in the United States. The cause of NAFLD is poorly defined but is thought to involve complex interactions of genetic and environmental factors.
- Trial name
- NCT01643512
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Lymphoma
Safety Trial of NK Cell DLI 3-5/6 Family Member Following Nonmyeloablative ASCT
Evaluate the safety of natural killer (NK) cell infusion using CD56 monoclonal antibody selected with Miltenyi Biotec system following nonmyeloablative stem cell transplantation (SCT) from mismatched donors.
- Trial name
- NCT00586703
- Testing
- NK-CD56
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- David Rizzieri, MD
Congenital Muscular Torticollis, Family Members
The Effect of Home Exercise Programs Applied of Congenital Muscular Torticollis.
Congenital muscular torticollis (CMT) is the third most common musculoskeletal disorder of infancy, affecting 3.9% to 16% of infants.
- Trial name
- NCT06225934
- Testing
- Exercise and home program to increase lateral flexion and rotation angles
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Gazi University
Implantable Defibrillator User, Terminal Illness
GAMification to Encourage End-Of-Life Discussions Between ICD Patients and Caregivers
The purpose of this study is to determine the feasibility and efficacy of the GAMification to Encourage End-Of-Life (GAME-EOL) intervention, which uses the Hello Game program to encourage and facilitate quality end-of-life (EOL)…
- Trial name
- GAME-EOL (NCT04994782)
- Testing
- GAME-EOL
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Debra Moser
Acceptability of Health Care
The Correlation Between Family Member Presence and The Consent for Regional Anaesthesia for Caesarean Section
Patient's safety and satisfaction are major concerns of anesthesiologists and obstetricians. According to evidence guidelines, and quality markers, regional anesthesia is preferred over general in obstetric surgery.
- Trial name
- BSU (NCT04614220)
- Testing
- Presence of Family member
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Beni-Suef University
Refractory Epilepsy, SLC35A2-CDG - Solute Carrier Family 35 Member A2 Congenital Disorder of Glycosylation
Galactose Supplementation for the Treatment of MOGHE
Mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) is a new entity frequently associated with refractory epilepsy and neurodevelopmental disorders.
- Trial name
- GATE (NCT04833322)
- Testing
- D-Galactose
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- Hospital Ruber Internacional
Family Members, Cancer
Evaluation of FROM-16 in ATMP Patients & Families
Poor health, and its treatment, has impact beyond the healthcare system into wider society. A person's productivity, taxable earnings, benefit payments and community contribution may all be adversely affected by poor health.
- Trial name
- NCT05141318
- Testing
- FROM-16 Questionnaire, Semi-structured two-part interview
- Where
- 5 sites in United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Swansea University
Dementia, Alzheimer Disease
Assessing Acceptability, Cost, and Efficacy of STELLA-Support Via Technology
STELLA (Support via Technology Living and Learning with Advancing Alzheimer's disease and related dementias) is a multicomponent video-conference based intervention that aims to help family members caring for persons of dementia…
- Conditions
- Dementia, Alzheimer Disease, Caregiver Burnout, Family Members
- Trial name
- STELLA (NCT04335110)
- Testing
- STELLA (Support via TEchnology: Living and Learning with Advancing Alzheimer's disease and related dementias)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Oregon Health and Science University
Advanced-stage Solid Tumors
A Study of JNJ-89862175 for Treatment of Advanced Solid Tumors
The purpose of this study is to determine safe and effective dose (recommended phase 2 doses [RP2Ds]) of JNJ-89862175 in Part 1 (dose escalation), and to further evaluate how safe JNJ-89862175 is at the RP2Ds in Part 2 (dose…
- Trial name
- NCT07223125
- Testing
- JNJ-89862175
- Where
- 6 sites in United States, France and 1 more
- Volunteers
- 360 people
- Sponsor
- Janssen Research & Development, LLC
Family Members, Diabetes Mellitus
The Effect of Family Support on Diabetes Patients' Health Beliefs, Behavioral and Metabolic Results
This study, designed according to the randomized pre-test and post-test control group experimental model, will be carried out with the patients who apply to the Diabetes Education Unit of Samsun Training and Research Hospital The…
- Trial name
- NCT04883424
- Testing
- Diabetes Education Program Based on Health Belief Model
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Ondokuz Mayıs University
Quality of Life
Effects of the MBHP on the Quality of Life of Family Members of People With Intellectual Disability
The research aims to verify the effects of the Mindfulness Based Health Promotion (PSBM) program on the quality of life of mothers of person with intellectual disability.
- Trial name
- caregivers (NCT03756441)
- Testing
- Mindfulness meditation, Psychotherapy group
- Where
- Brazil
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Centro Mente Aberta de Mindfulness
PD-1 Antibody, CAR-T Cells
PD-1 Antibody Expressing CAR-T Cells for EGFR Family Member Positive Advanced Solid Tumor
To evaluate the safety and effectiveness of cell therapy using herinCAR-PD1 cells to treat advanced cancer. Individuals greater than or equal to 18 years of age and less than or equal to 70 years of age who have been diagnosed…
- Conditions
- PD-1 Antibody, CAR-T Cells, Advanced Malignancies
- Trial name
- NCT02873390
- Testing
- HerinCAR-PD1 cells
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Ningbo Cancer Hospital
Hearing Loss, Pendred Syndrome
Clinical Phenotypic Characteristics of SC26A4
The presence or absence of SC26A4, whether combined with Mondini malformation, and patient age, are important factors affecting the degree of hearing loss in the Chinese population.
- Trial name
- NCT05970445
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chinese PLA General Hospital
Chronic Nonmalignant Pain
Family Nursing Conversations Patients With Chronic Non-Cancer Pain
This study assumes that family nursing will enhance the management of chronic nonmalignant pain (CNP) for the patients and their family members.
- Trial name
- FANCOC-PAIN (NCT03981302)
- Testing
- Family nursing conversations
- Where
- Denmark
- Volunteers
- 143 people
- Sponsor
- Bente Appel Esbensen
Psychological Distress, Depression
Mobile Mindfulness to Improve Psychological Distress After Critical Illness
Many survivors of the intensive care unit (ICU) suffer from persistent symptoms of depression, anxiety, and post-traumatic stress disorder (PTSD).
- Conditions
- Psychological Distress, Depression, Anxiety, Post-traumatic Stress Disorder
- Trial name
- NCT02701361
- Testing
- mobile mindfulness, standard mindfulness, education
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Duke University
Advanced Cancer
Identifying Family Members in Need of Support While Caregiving and After Loss
This screening tool will be used to identify significant relations of patients with advanced medical illness or serious hospitalization and family individuals who lost their loved one and who could use professional support in the…
- Trial name
- NCT02455505
- Testing
- background questionnaire, bereavement risk screening tool
- Where
- 2 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Frontotemporal Dementia, Family Members
Genetic Frontotemporal Dementia Initiative for Neurodevelopment
This is an international multi-centre cohort study of first and second degree family members of individuals who carry Frontotemporal Dementia (FTD) mutations in MAPT, GRN or C9ORF72 repeat expansions for youths between the ages…
- Trial name
- GENFI-NeuroDev (NCT05779813)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Western University
Schizophrenia, Schizoaffective Disorder
The Effectiveness of FMPO in Improving the Quality of Care for Persons With Severe Mental Illness.
The purpose of this study is to learn how to help veterans play a stronger role in shaping their mental health care. Specifically we want to see if we can help veterans improve their mental health treatment by helping them decide…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Major Depression
- Trial name
- NCT00466323
- Testing
- Family Member Provider Outreach, Enhanced treatment as usual (e-TAU)
- Where
- 2 sites in United States
- Volunteers
- 238 people
- Sponsor
- US Department of Veterans Affairs
Spinal Cord Injury
Enhancing Self-Efficacy for Caregivers of Family Members With Spinal Cord Injury
Spinal cord injury (SCI) may result in physical deficits that require assistance from others in order to stay healthy and live independently in a community.
- Trial name
- NCT02392052
- Testing
- Reinvention Protocol Participants, Wait List
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Craig Hospital