Clinical trials: Family Functioning
Alcohol Abuse
Brief Intervention for Families of Teens Treated in the Emergency Department for an Alcohol-Related Event
The purpose of this study is to compare the effectiveness of a brief family intervention in reducing alcohol use and alcohol-related problems among families of underage drinkers (13-17 years old) who are treated in a hospital…
- Trial name
- NCT00247221
- Testing
- MI/Family Check-up, MI only
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Brown University
Mental Health (Depression), Mental Health and General Well-being
Thrive at Home: A Virtual Reality Social Intervention for Older Adults
The goal of this clinical trial is to evaluate whether a virtual reality (VR) based social platform can improve mental health and social connection for older adults who receive in-home care.
- Conditions
- Mental Health (Depression), Mental Health and General Well-being, Loneliness, Well Being
- Trial name
- Thrive at Home (NCT07835568)
- Testing
- Full Virtual Reality Social Intervention, Abbreviated Virtual Reality Social Intervention
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, Santa Barbara
Healthy
Functional Neuroimaging of Alcoholism Vulnerability (PIT)
This project compares Family History Positive (FHP) for alcoholism subjects to matched Family History Negative (FHN) subjects derived from the project Principal Investigator's National Institute on Alcohol Abuse and…
- Trial name
- CTNA (NCT01585168)
- Testing
- Memantine
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Yale University
Hypohidrotic Ectodermal Dysplasia
Characterization of Sweat Gland Function in Patients With Recessively Inherited Hypohidrotic Ectodermal Dysplasia
Hypohidrotic ectodermal dysplasia (HED) is a complex genetic disorder characterized by lack of sweat glands, sparse hair, and missing or malformed teeth.
- Trial name
- NCT01109290
- Where
- Germany
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University Hospital Erlangen
Family Resilience, Short-term Therapy
Home Within the Heart: a Playful Journey to Strengthen Family Resilience
The primary aim of this clinical trial is to enhance open and secure communication within the family, strengthen the parent-child bond, and reinforce feelings of safety and stability, and strengthen family resilience.
- Conditions
- Family Resilience, Short-term Therapy, The Integration of Narrative Therapy and Play Therapy
- Trial name
- NCT06592651
- Testing
- Play Therapy Workshop
- Where
- Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Intellectual Deficiency, Asymptomatic Carrier of the Mutation of the Gene MYT1L
Development of the Tool " iPSC " for the Functional Study of Mutations Responsible for Mental Retardation
According to the World Health Organization (WHO), mental retardation (MR) is defined by an intelligence quotient (IQ) < 70 and touches between 1 to 3 % of the general population.
- Conditions
- Intellectual Deficiency, Asymptomatic Carrier of the Mutation of the Gene MYT1L, Healthy Volunteers
- Trial name
- Rementips (NCT02980302)
- Testing
- Cutaneous biopsy
- Where
- France
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Caregiver Stress, Caregiver Stress Syndrome
ACT Group for Family Caregivers of Stroke Survivors
The goal of this study is to evaluate the efficacy of group-based ACT intervention in improving the levels of psychological distress in caregivers of stroke survivors. The main questions it aims to answer are: 1.
- Conditions
- Caregiver Stress, Caregiver Stress Syndrome, Caregiver Burnout, Caregiver Distress
- Trial name
- NCT07528261
- Testing
- Group-based ACT Intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Wright Institute
Psychiatric Disorder
Familial and Functional Study of Genetic Variants Identified in People With Schizophrenia, Bipolar Disorder, Autism Spectrum Disorder or Resistant Depression
Genetic analyses conducted on patient with psychiatric disorders assessed at the expert centres resulted in the identific action of genetic variants associated with psychiatric disorders (Courtois, 2020).
- Trial name
- GENI (NCT05480826)
- Testing
- study of the transmission of genetic variants
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fondation FondaMental
Insulin Resistance, Dementia
Effects of Liraglutide on Hippocampal Structure and Function in Aging Adults With Prediabetes
The purpose of this study is to evaluate the effects of liraglutide on the memory and attention of people with insulin resistance.
- Trial name
- LGT (NCT02140983)
- Testing
- Liraglutide
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Stanford University
Familial Mediterranean Fever, MEFV Gene Mutation
Characterization of a Functional Test for Mediterranean Family Fever Screening - 2
Familial Mediterranean fever (FMF) is the most common auto-inflammatory disease (prevalence: 1-5 / 10,000 inhabitants). It is caused by mutations in the MEFV gene, which encodes variants of the Pyrine inflammasome.
- Trial name
- DEPIST-FMF 2 (NCT04478409)
- Testing
- one additional blood sample during a planned blood test
- Where
- 8 sites in France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Emotional Intelligence, Social Interaction
Efficacy of iMentalize and MISC-SA to Foster Parents' Mentalization and Children Mental Health in General Population.
OBJECTIVES: The goal of this parallel randomized controlled trial is to test the efficacy of the iMentalize program and the Mediational Intervention for Sensitizing Caregivers - Self Administered version (MISC-SA) to foster…
- Conditions
- Emotional Intelligence, Social Interaction, Mental Health Wellness 1, Well-Being, Psychological
- Trial name
- iMentalize (NCT06270732)
- Testing
- iMentalize Program (iMentalize), Mediational Intervention for Sensitizing Caregivers, Self-Administered version (MISC-SA), Mediational Intervention for Sensitizing Caregivers - Readings version (MISC-R): Treatment as Usual (TAU)
- Where
- 2 sites in Spain
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Universitat Autonoma de Barcelona
Adolescent - Emotional Problem, Parent-Child Relations
Family-Focused Adolescent &Amp; Lifelong Health Promotion Optimization Trial
The aim of this study is to conduct a multi-country, cluster-randomized factorial trial to optimize the Parenting for Lifelong Health (PLH) for Parents and Teens program in Moldova and North Macedonia.
- Conditions
- Adolescent - Emotional Problem, Parent-Child Relations, Family Functioning, Well-Being, Psychological
- Trial name
- FLOURISH (NCT06562244)
- Testing
- Parenting for Lifelong Health for Parents and Teens (PLH), Helping Adolescents Thrive comics, I Support My Friends
- Where
- North Macedonia
- Volunteers
- 1,316 people, healthy volunteers welcome
- Sponsor
- University of Klagenfurt
Adolescent - Emotional Problem, Parent Child Relationship
Randomized Controlled Trial of a Family-focused Intervention for Caregivers and Young Adolescents (Phase 3 of FLOURISH)
The aim of this study is to conduct a multi-country randomized waitlist controlled trial to evaluate the effectiveness, cost-effectiveness, and scalability of the optimized Parenting for Lifelong Health (PLH) for Parents and…
- Conditions
- Adolescent - Emotional Problem, Parent Child Relationship, Family Functioning, Well-Being, Psychological
- Trial name
- FLOURISH (NCT07240571)
- Testing
- Optimized Parenting for Lifelong Health (PLH) for Parents and Teens
- Where
- 2 sites in Moldova, North Macedonia
- Volunteers
- 1,280 people, healthy volunteers welcome
- Sponsor
- University of Klagenfurt
Intensive Care Neurological Disorder
Patient and Caregiver Psychological Functioning Following Neuro-ICU Admission: A Prospective Investigation
The current study has the following objectives: 1. To determine predictors of time 2 and 3 (3 and 6 months post-ICU admission) depression, PTSD, satisfaction with life and quality of life in both patients and caregivers, after…
- Trial name
- NCT02435641
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Stress, Psychological, Child Behavior
Tele-Wellness Supported App for Family Child Care Home Providers and Families to Promote Health, Family Engagement, and School Readiness Amid COVID-19
The investigators aim to deliver a tele-wellness supported app to Baltimore City's Family Child Care Home (FCCH) providers who are caring for children of Essential Personnel.
- Conditions
- Stress, Psychological, Child Behavior, Social Competence
- Trial name
- NCT04453657
- Testing
- FamilyChildCare (provisional name of app)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
X-linked Hypophosphatemia, Hereditary Hypophosphatemia
Characterising Pain, QoL, Body Composition, Arterial Stiffness, Muscles and Bones in Adult Persons With XLH and Healthy Controls
Hereditary hypophosphatemia (XLH) is a rare, inherited disease. Loss-of-function mutation in the phosphate regulating gene with homologies to endopeptidases on the X-chromosome (PHEX) results in excess fibroblast growth factor 23…
- Trial name
- NCT04273490
- Where
- Denmark
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Caregiver, Lobectomy Patient
Physical Activity Intervention Before and After Surgery in Older Adults With Lung Cancer and Their Family Caregivers
This trial studies whether a telephone-based physical activity intervention before and after lung cancer surgery can be provided to older patients and their caregivers.
- Conditions
- Caregiver, Lobectomy Patient, Lung Carcinoid Tumor, Lung Non-Small Cell Carcinoma
- Trial name
- NCT04085081
- Testing
- E-mail, Exercise Intervention, Quality-of-Life Assessment
- Volunteers
- healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Alcoholism
The Tolerability and Effects of AZD0530 in Individuals With or Without a Family History of Alcoholism
Functional neuroimaging of alcoholism vulnerability: glutamate, reward, impulsivity, and Pavlovian-to-instrumental transfer (PIT), part II Saracatinib
- Trial name
- NCT02262026
- Testing
- 125 mg AZD0530, 50 mg AZD0530
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Yale University
Obesity
Family Functioning in Obesity Treatment for Mexican Americans
Mexican American families share similar elevated risks for obesity and obesity-related conditions, such as type 2 diabetes. Because negative family interactions and relationships (e.g., poor communication, high conflict, low…
- Trial name
- NCT05120804
- Testing
- Standard behavioral treatment, Standard behavioral treatment plus relationship skills training
- Where
- 2 sites in United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Becky Marquez
Premenstrual Syndrome, Exercises
Effect of Online Exercises for Premenstrual Syndrome on Couple's Stress and Family Function
Universe of Research The universe of the research; It will consist of women and their spouses with premenstrual syndrome complaints who use social media. 3.6.
- Conditions
- Premenstrual Syndrome, Exercises, Stress Level, Family Characteristics
- Trial name
- NCT06370429
- Testing
- Progressive Relaxation Exercises, randomized pretest-posttest
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University