Clinical trials: Family
Oppositional Defiant Disorder, Conduct Disorder
Multi-Family Group Therapy for Reducing Behavioral Difficulties in Youth
This study will examine the effectiveness of a multiple family group mental health service delivery strategy in improving mental health service use and outcome for urban, low income children of color, ages 7-11 years old with…
- Trial name
- NCT00404911
- Testing
- MFG therapy, Standard of Care
- Where
- United States
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Prostate Cancer
Eflornithine in Treating Patients At High Risk of Developing Prostate Cancer
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development of cancer. The use of eflornithine (DMFO) may be an effective way to prevent the development of prostate cancer.
- Trial name
- NCT00006101
- Testing
- eflornithine
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Thomas E. Ahlering
Cardiac Amyloidosis
Description of a Retrospective Cohort of Patients With Transthyretin Cardiac Amyloidosis (ATTR-CA) in Internal Medicine
In 2024, the prevalence of TTR cardiac amyloidosis is difficult to determine precisely. Indeed, the disease has long been underdiagnosed due to a lack of effective treatment and non-invasive diagnostic methods.
- Trial name
- ATTR-CA (NCT06907836)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Assisted Reproductive Technology
Family Foundations for Individuals Pregnant Via ART
The purpose of this study is to help expectant mothers build a coparenting bond and improve communication with a support person (co-caregiver).
- Trial name
- NCT06770972
- Testing
- Family Foundations
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Cedars-Sinai Medical Center
Lung Cancer
Low-dose Computed Tomography Screening for Lung Cancer in Relatives With Family History of Lung Cancer
Screening with the use of low-dose computed tomography (LDCT) reduces mortality from lung cancer. Relatives with family history of lung cancer are at increased risk of lung cancer compared to those without a family history in…
- Trial name
- NCT02519972
- Testing
- low dose computed tomography
- Volunteers
- 1,102 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Cardiac Arrest, Post Traumatic Stress Syndrome
Family-Authored ICU Diaries to Reduce Fear in Patients Experiencing a Cardiac Arrest (FAID Fear)
The present study will: Aim 1: Enroll 15 family members of CA patients to (a) pilot recruitment procedures, (b) estimate retention, and (c) assess acceptability of study procedures.
- Trial name
- FAID Fear (NCT05144477)
- Testing
- FAID Fear Intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Columbia University
Obesity, Childhood
Intervention INC: An Interactive Family-centered mHealth Tool to Reduce Obesity Risk in Urban Minority Preadolescents
Using a two-group randomized study design, this study aims to evaluate the effectiveness of the adapted family-centered mHealth tool on child BMI z-score (primary outcome), child dietary behaviors, and parental feeding practices…
- Trial name
- NCT05935592
- Testing
- Web-based comic and newsletters, Didactic health information
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tufts University
Parent-Child Relations
Family Foundations Coparenting Pilot Trial
This is a research study to evaluate the effectiveness of the Family Foundations program and to better understand how families cope with having a new baby.
- Trial name
- FF1 (NCT01901536)
- Testing
- Family Foundations Coparenting Program
- Where
- United States
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- Penn State University
Familial Hypercholesterolemia
Brazilian Cardioprotective Diet, Phytosterols and Krill Oil in Patients With Familial Hypercholesterolemia
The main objective of this pilot study is to evaluate the effects of the Brazilian Cardioprotective Diet (DICA Br) supplemented or not with phytosterols and/or krill oil in patients with a probable or definitive diagnosis of…
- Trial name
- DICA-HF (NCT05695937)
- Testing
- phytosterol, krill oil
- Where
- 9 sites in Brazil
- Volunteers
- 58 people
- Sponsor
- Hospital do Coracao
Dementia, Family
Supporting Family Caregivers of Persons Living With Dementia: Effectiveness and Sustainability of MT4C-In Care
When a person living with dementia moves into a long term care facility, their family members remain involved in their care. They learn new roles and make significant and often stressful adjustments.
- Trial name
- NCT04226872
- Testing
- My Tools for Care - In Care
- Where
- 4 sites in Canada
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Stroke
ATTEND-Family-led Rehabilitation After Stroke in India
ATTEND Trial is based on early supported discharge- home based stroke rehabilitation model which proves to offer several advantages in low and mid income countries.
- Trial name
- ATTEND (NCT02123875)
- Testing
- Physiotherapy, Control arm
- Where
- India
- Volunteers
- 104 people
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Familial Renal Glucosuria, Diabetes Mellitus
Human Solute Carrier Family 5 Member 2 (SLC5A2) Deficiency and the Glucagon-Incretin Axis
Sodium-glucose-cotransporter 2 (SGLT2) are a new type of oral antidiabetic drugs. SGLT2 inhibitors increase the urinary glucose excretion and thereby decrease blood glucose levels.
- Conditions
- Familial Renal Glucosuria, Diabetes Mellitus, Cardiovascular Diseases
- Trial name
- NCT03965000
- Testing
- Mixed-meal-tolerance-test
- Where
- Austria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Intrahepatic Cholangiocarcinoma (Icc)
Liver Transplantation for Unresectable Intrahepatic Colangiocarcinoma After Sustained Response to Neoadjuvant Treatments
This is single-arm, observational, academic, investigator-driven study investigating the efficacy of liver transplantation after successful and sustained downstaging/tumor control of liver-limited unresectable intrahepatic…
- Trial name
- iCOLA (NCT06862934)
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Autism Spectrum Disorder
Promoting Transactional Supports to Optimize Social Communication Outcomes for Infants and Their Families
This early treatment project is designed to address two significant public health challenges - the need for validated, manualized, treatments for young children with Autism Spectrum Disorder (ASD) that are cost-efficient and…
- Trial name
- NCT03307057
- Testing
- Social Communication Growth Charts (SCGC), Parent-Implemented (P-I) Condition, Clinician-Implemented (C-I) Condition
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- Emory University
Suicide, Suicidal Ideation
Piloting a Culturally Adapted Suicide Prevention for Black Students in Chicago
Suicide has been the third leading cause of death for Black youth in the U.S since the 1980s and persists as a leading cause of death for Black youth today.
- Conditions
- Suicide, Suicidal Ideation, Suicide Attempt
- Trial name
- SP-BSC (NCT07125144)
- Testing
- Black Youth Suicide Prevention in Chicago, Signs of Suicide: Standard/Existing
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Quality of Life
The Dementia Quality of Life Scale for Older Family Carers (DQoL-OC) Study
The purpose of this research is to develop the "DQoL-OC", a unique questionnaire to evaluate the quality of life of people aged 60 or above providing care for a family member with Alzheimer's disease or other related dementia at…
- Trial name
- DQoL-OC (NCT02463734)
- Where
- 14 sites in United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Educational Activities
Facilitating COVID-19 Test for Korean Americans Through Korean Schools in Northern California
In collaboration with Korean Schools of Northern California, the investigators will test if a community-based intervention delivered by lay health educators (LHEs) increases testing uptake among Korean Americans.
- Trial name
- NCT05435482
- Testing
- Education, COVID-19 testing kits, Instruction
- Where
- United States
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Colorectal Neoplasms
Adding Family History of Colorectal Cancer to the Dutch FIT-based Screening Program
The aim of this study is to identify more persons with advanced neoplasia in the current national CRC screening, by adding data on family history of CRC (using a validated online questionnaire) to FIT.
- Trial name
- NCT02698462
- Testing
- Family history questionnaire
- Volunteers
- 6,000 people
- Sponsor
- Prof. Evelien Dekker, MD, PhD
Autism
To Share or Not To Share: Navigating Disclosure and Stigma Among Family Caregivers of Autistic Young Adults_Group Intervention
This study is a caregiver support program for family caregivers of autistic young adults (ages 18 to 26) as their family members navigate young adulthood.
- Trial name
- NCT07856927
- Testing
- Group Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Wisconsin, Madison
Non-Small Cell Lung Cancer, Advanced Lung Cancer
Nurse-Led Caregiver Support for Older Adults With Advanced Lung Cancer
This two-phase study aims to examine the current status of older adults with newly diagnosed locally advanced or advanced non-small cell lung cancer and their primary family caregivers, and to evaluate the effects of the…
- Conditions
- Non-Small Cell Lung Cancer, Advanced Lung Cancer, Caregiver Burden, Resource Utilization
- Trial name
- ICSM (NCT07708870)
- Testing
- Integrating Nurse-Led and Resource Utilization-Based Caregiver Support Model, Oncology Case Manager Care and Usual Care
- Where
- 2 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital