Clinical trials: Facial Scarring
Acne, Acne Scars
Comparison of Stacked-Pulses Vs. Double-Pass Treatments of Facial Acne With a 1450 Nm Laser
Acne can be treated with a mid-infrared laser. We demonstrated safety and efficacy using lower energy settings in order to make the treatments less painful
- Trial name
- NCT00306371
- Testing
- 1450nm diode laser
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Skincare Physicians of Chestnut Hill
Scar
Fractional Laser Therapy and Dermabrasion for Scar Revision
The goals of this study will be to compare the safety and efficacy of fractional photothermolysis (Fraxel) with dermabrasion when used for scar revision.
- Trial name
- NCT01409863
- Testing
- laser and standard diamond fraise dermabrasion
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Acne Scars
A Pilot Study Testing the Efficacy of a Needling Device for the Treatment of Acne Scars
The primary objective of this study is to determine the efficacy of a needling device for treatment of acne scars.
- Trial name
- NCT00974870
- Testing
- needling treatment
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Atrophic Scar
Safety and Efficacy of Autologous Adipose-derived Mesenchymal Stem Cells Therapy in Adults With Atrophic Scars
The purpose of this clinical trial was to evaluate the safety and efficacy of a single administration of TRTP-101 in adults with atrophic scars.
- Trial name
- NCT07474467
- Testing
- TRTP-101
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- CellinCells
Healthy Volunteers
Performance and Safety of Restylane Lidocaine for Treatment of Depressed Facial Acne Scars
The purpose of this study is to evaluate performance and safety of Restylane Lidocaine for treatment of depressed facial acne scars
- Trial name
- NCT03127384
- Testing
- Restylane Lidocaine, No-treatment control
- Where
- 2 sites in Germany
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Wrinkles, Acne Scars
Epidermal Delivery of Ani-Aging Ingredients
To assess the safety and efficacy of an ablative fractional, 2940-nm laser combined with the US Impact and cosmetic -formulations for improving the appearance of wrinkles, acne scars and pigmented skin.
- Conditions
- Wrinkles, Acne Scars, Pigmentation
- Trial name
- NCT01847066
- Testing
- Erbium 2940 plus cosmetics plus Impact, Erbium 2940 plus cosmetics
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Alma Lasers Inc.
Acne Scars - Mixed Atrophic and Hypertrophic, Ice Pick Scars
Evaluation of Efficacy and Safety of HCC_45 for the Correction of Acne Scars of the Face
Acne scars represent a frequent complication of moderate/severe acne and may negatively impact on psychosocial and physical well-being of acne patients.
- Conditions
- Acne Scars - Mixed Atrophic and Hypertrophic, Ice Pick Scars, Rolling Scars, Boxcar Scars
- Trial name
- NCT05691049
- Testing
- HCC_45
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IBSA Farmaceutici Italia Srl
Acne Scars
Comparison of 1550nm Fractional Laser Alone Versus in Combination With Microneedling for the Treatment of Acne Scars
Acne scarring is an unfortunate consequence of inflammatory acne vulgaris that often leads to significant cosmetic and psychosocial impacts.
- Trial name
- NCT03901417
- Testing
- Fraxel Restore (Non-ablative Fractional Laser), Fraxel Restore (Non-ablative fractional laser) and SkinPen (Microneedling Device)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Skin Scarring, Skin Elasticity
Skin Elasticity Measurements of the Face and Surgical Scars Stratified by Age and Skin Type
The primary objective of Part A is to compare the change in elasticity measurements at baseline and at 3 months between subjects who have had a resurfacing or tightening procedure and those who have not.
- Trial name
- NCT01688063
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Acne, Atrophic Scar
Comparison of Picosecond Lasers vs. Ablative Fractional Er:YAG Lasers in Treating Atrophic Scar
The 1064-nm Nd:YAG picosecond lasers using fractional micro-lens array (P-MLA) was a promising therapy for skin resurfacing. However, no studies have compared P-MLA with ablative fractional 2940-nm Er:YAG lasers (AF-Er) in…
- Trial name
- NCT05686603
- Testing
- a fractional 1064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) picosecond laser with MLA handpiece, a ablative fractional 2940-nm Er:YAG laser
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acne Scars - Atrophic
Stromal Vascular Fraction Enriched PRP in Treatment of Post-acne Scars
in a split face fashion, 30 patients will be randomized into 3 groups: Group A: rt side treated with SVF enriched PRP, lt side treated with prp Group B: rt side treated with SVF enriched PRP, lt side treated with SVF Group C: rt…
- Trial name
- NCT06524011
- Testing
- Stromal vascular fraction (SVF) enriched platelet rich plasma (PRP) versus each alone
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Hypertrophic Scarring
Clinical Evaluation of the Efficacy OF Botulinum Toxin A for Improving Facial Scars
Background: Scars widen when the overlying musculature pulls apart suture lines. Because Botulinum Toxin A (BTA) is known to prevent fibroblast proliferation and it also induces temporary muscle paralysis, the purpose of this…
- Trial name
- NCT04756882
- Testing
- AbobotulinumtoxinA 500 UNT
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Acne Scars
Lasers to Aid in Treatment of Acne Scars
To assess efficacy and safety of paired picosecond 755nm Alexandrite laser with focused lens array (PSAL; Picosure®, Cynosure, Westford, MA) and radiofrequency microneedling (RFM; Potenza™, Cynosure, Westford, MA) for treatment…
- Trial name
- NCT05579171
- Testing
- Picosecond 755nm Alexandrite Laser
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Acne Scars
Comparison of 1,550-nm Laser and Fractional Radiofrequency Microneedle for the Treatment of Acne Scars in Ethnic Skin
The primary objective of this randomized, split-face, controlled study is to compare the efficacy and safety of a erbium-doped 1,550-nm non-ablative fractional laser and a bipolar fractional radiofrequency microneedle device for…
- Trial name
- NCT03380845
- Testing
- Fraxel Restore, Fractora
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Suture; Complications, Mechanical, Scar
Comparing 1 Week Versus 2 Week Cutaneous Suture Removal
Our goal is to compare the difference in surgical outcomes and patient satisfaction for surgical scars on the face between suture removal at 1 week versus 2 weeks.
- Conditions
- Suture; Complications, Mechanical, Scar, Surgery
- Trial name
- NCT05267002
- Testing
- Suture removal timing
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- DermSurgery Associates
Skin Fold, Skin Laxity
A Safety and Effectiveness Study of CELLBOOSTER® Lift (Stabilized Booster Complex Using CHAC Technology)
The current post-market clinical investigation has been designed to evaluate the efficacy and safety of CELLBOOSTER® Lift, a HA-based product marketed by SUISSELLE SA.
- Conditions
- Skin Fold, Skin Laxity, Skin Texture Disorder, Skin Depression
- Trial name
- NCT06000839
- Testing
- (D0) Intradermal injection - micropapula technique, (D14) Intradermal injection - micropapula technique, (D28) Intradermal injection - micropapula technique
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Suisselle
Acne Vulgaris
Treatment of Acne Scars With Erbium:Yttrium Aluminum Garnet (Er:YAG) Laser Examined Under OCT
This study is examining the effects of the 2940 nm Er:YAG on atrophic facial acne scars under optical coherence tomography in terms of blood flow, vessel shape, skin roughness, collagen content, and epidermal thickness.
- Trial name
- NCT03333759
- Testing
- Alma - Harmony XL Laser
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Acne Scars
Effect of Multiple Subcisions on Rolling Acne Scars
The purpose of this study is to find out whether the use of multiple subcisions over several visits will improve the appearance of rolling acne scars compared to no treatment.
- Trial name
- NCT02216864
- Testing
- Multiple Subcision
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Atrophic Acne Scar
Combined Therapy for Acne Scars
Compare the effectiveness of nonablative fractional resurfacing to radiofrequency micrnoeedling for facial acne scars in all skin types
- Trial name
- NCT05105334
- Testing
- Nonablative fractional laser (Fraxel re:store, Solta Medical, Bothell, WA) alone, Nonablative fractional laser (Fraxel re:store, Solta Medical, Bothell, WA) alternating with microneedling with radiofrequency (Intracel, Perigee Medical, Redwood City, CA)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Acne Scars - Mixed Atrophic and Hypertrophic, Acne
Pilot Study Investigating the Efficacy of Fat Grafting as a Treatment for Male and Female Facial Acne Scarring
This single-center, clinical trial consists of a one autologous fat grafting treatment followed by 3-month and 6-month post-treatment visits in order to assess the efficacy of fat grafting when used by men and women with facial…
- Trial name
- NCT04559022
- Testing
- Fat Grafting
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center