Clinical trials: Facial Aging
Facail Skin Aging
Facial Exercise and Daily Habit Modification Program for Skin Quality and Wrinkle Severity in Middle-Aged Women
This randomized controlled trial will evaluate the effectiveness of a 12-week program combining facial muscle exercises and daily habit modification for improving skin quality and reducing wrinkle severity in middle-aged women.
- Trial name
- NCT07792460
- Testing
- Facial Exercise and Daily Habit Modification Program
- Where
- Iraq
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of Zakho
Facial Aging, Facial Wrinkles and Rhytides Reduction
Intradermal Microbotulinum Toxin for Sebum Reduction and Facial Pore Improvement
This study aims to evaluate the efficacy and safety of microdoses of botulinum toxin type A (microtoxin) for improving periocular skin quality and reducing fine wrinkles.
- Trial name
- MICROTOX-PORE (NCT07526870)
- Testing
- Botulinum Toxin Type A (Dysport®)
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Skin Aging
Autologous Fibroblast Grafts in Facial Skin Regeneration
The purpose of this study is to evaluate the presence of skin changes after grafting of autologous fibroblasts by means of biophysical, histological, immunohistological, gene expression, glycosaminoglycan, and sensitivity…
- Trial name
- NCT01490554
- Testing
- autologous fibroblasts grafts
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Facial Aging, Melomental Folds
Botulinum Toxin Type A Injection Sites for Oral Commissure Ptosis
This multicenter, prospective, randomized parallel-controlled, assessor-blinded clinical trial aims to address the core clinical pain point of lack of high-level evidence and non-standardized operation in injection site selection…
- Conditions
- Facial Aging, Melomental Folds, Oral Commissure Ptosis
- Trial name
- NCT07646886
- Testing
- OnabotulinumtoxinA (Upper Depressor Anguli Oris Injection), OnabotulinumtoxinA (Lower Depressor Anguli Oris Injection)
- Volunteers
- 266 people
- Sponsor
- Peking University
Facial Wrinkles, Skin Hydration
Oral Supplementation With Active Collagen Peptides and Skin Health Improvement
The present study aims to investigate the efficacy of daily supplementation with COLLinstant® LMW over a 6-week period in improving visible signs of aging.
- Trial name
- NCT06321770
- Testing
- Bioactive collagen peptides
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Gala Servicios Clinicos S.L.
Aging, Pain
RHA® 4 With New Anesthetic - Nasolabial Folds
This is a randomized, controlled, double-blinded, within-subject (split-face), multicenter, prospective study to investigate whether RHA® 4 with New Anesthetic Agent is non-inferior to RHA® 4 (with lidocaine) in terms of…
- Trial name
- NCT04087395
- Testing
- RHA®4 with new anesthetic agent, RHA®4-Lidocaine
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Wrinkle, Photoaging
Clinical Study To Evaluate Paired Treatment With An Alexandrite Laser And Radiofrequency Microneedling For Facial Aging
The intended use of the radiofrequency and microneedling devices used in this study is to assess the efficacy and safety of paired treatment for the treatment of facial aging.
- Conditions
- Wrinkle, Photoaging, Dyschromia
- Trial name
- NCT05388604
- Testing
- RF device, Microneedling device
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Cynosure, Inc.
Aging Problems
Safety and Performance of DKL Crosslinked Sodium Hyaluronate 26 Dermal Filler for Cheek Augmentation
This is a pivotal, prospective, active-controlled, randomized, double blinded (blinded evaluator and subject), intra-individual split-face comparison, non-inferiority study of DKL crosslinked sodium hyaluronate 26 versus Juvederm…
- Trial name
- NCT05021926
- Testing
- DKL crosslinked sodium hyaluronate 26, Juvéderm Voluma™ with lidocaine (Allergan, Inc)
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr. Korman Laboratories Ltd.
Skin Aging
Safety and Efficacy of a Microneedling Device Used in Facial Aesthetics
Microneedling (MN), also referred to as collagen induction therapy, uses small needles to create mechanical injury to the skin. The basis of MN relies on physical trauma.
- Trial name
- NCT06933225
- Testing
- WOW fusion Microneedling Device, 1.00 mm
- Where
- France
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Circa Skin Ltd
Skin Aging, Facial Wrinkles
Study of the Subdermal Implant "Algeness"
A single-center clinical study of the efficacy and safety of the medical device "Algeness subdermal implant based on agarose (Ghimas SpA/Ghimas SpA, Italy) in the correction of skin contour defects.
- Conditions
- Skin Aging, Facial Wrinkles, Soft Tissue Volume Loss, Lipoatrophy
- Trial name
- NCT07618468
- Testing
- Algeness Subdermal Implant (Agarose)
- Where
- Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Estelab Clinic
Stroke
Facial and Body Motion Technology and Stroke
The purpose of this study is to customize privacy protected facial expression and body motion tracking for use in the home environment by stroke survivor-informal caregiver dyads by investigating within a simulated home…
- Trial name
- NCT04592627
- Testing
- Simulated home environment visit
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- The University of Texas Health Science Center, Houston
Volume Deficiency in the Mid-Face, Aging
Study of STYLAGE® XXL for Volume Deficiency in the Mid-Face
The primary objective of the study is to demonstrate the superiority of STYLAGE® XXL versus no treatment at 24 weeks after baseline for the creation or restoration of volume deficit in the mid-face.
- Conditions
- Volume Deficiency in the Mid-Face, Aging, Aesthetics
- Trial name
- MidFaceXXL (NCT05355454)
- Testing
- STYLAGE® XXL
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Skin Aging
Multicenter, Prospective Study to Determine the Performance and Safety of the New M-HA30 Architect Device on the Quality of the Skin: HEBE8 Study
For skin rejuvenation the targeted population does not present a specific pathology. Aesthetic procedures are requested by the patient to improve appearance, look younger and feel better.
- Trial name
- HEBE8 (NCT07007351)
- Testing
- Intradermal injection
- Where
- France
- Volunteers
- 285 people
- Sponsor
- Laboratoires FILLMED
Skin Aging, Skin Quality
AnteAGE Exosomes and PEARL Multiplier With Microneedling for Facial Skin Quality
This exploratory clinical study evaluated changes in facial skin quality following a series of mechanical microneedling treatments combined with topical AnteAGE Exosomes and PEARL Multiplier and a standardized AnteAGE homecare…
- Trial name
- NCT07849205
- Testing
- Mechanical microneedling, AnteAGE Exosomes and PEARL Multiplier, AnteAGE Homecare Regimen
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cellese Inc.
Healthy Subjects, Healthy Adult
Development of a Clinical Photographic Atlas for Skin Aging Based on the Characterization of Facial Dermal Collagen Using LC-OCT Technology
This is a single-center, single visit study conducted in healthy female subjects, aged 20 to 75 years inclusive meeting specific inclusion/exclusion criteria.
- Trial name
- NCT07409675
- Testing
- LC-OCT acquisitions on the forehead, Perform standardized photographs using ColorFace, LC-OCT acquisitions on forehead
- Where
- France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Vichy Laboratoires
Wrinkles, Anti Aging
PER-SAF_PDOS (Performance and Safety of Polydioxanone Suture)
This clinical investigation aims to confirm the safety and efficacy of the ID in facial soft tissue reconstruction, specifically for non-incision surgery to tighten and lift the facial skin for a rejuvenated facial appearance.
- Conditions
- Wrinkles, Anti Aging, Face-lift
- Trial name
- PER-SAF_PDOS (NCT07068061)
- Testing
- PDO suture
- Volunteers
- 50 people
- Sponsor
- 21 Century Medical Co., Ltd.
Aging, Face; Atrophy
Fractional Laser Drug Delivery of a Local Anesthetic
The purpose of this study is to assess the clinical efficacy of fractional CO2 laser-assisted delivery of a topically applied anesthetic to the perceived pain during filler injection.
- Trial name
- NCT05734248
- Testing
- Facial filler injection
- Where
- 2 sites in Greece
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ioannina
Aging Problems, Pigmentation
16-Week Randomized Split-Face Efficacy Study of Cosmetic Formulations in Photoaged Pigmented Skin Subjects
The objective of this study is to determine the efficacy of seven different formulations currently marketed and commercially available cosmetic products on skin tone evenness, post-inflammatory hyperpigmentation, and discrete…
- Trial name
- NCT05160103
- Testing
- Cosmetic Formulations
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Avon Products, Inc.
Hyperpigmentation, Photodamaged Skin
A Multi-Center, Open-label Study Evaluate the Efficacy and Tolerability of a Dual Skincare Regimen Treatment for Facial Hyperpigmentation and Photodamaged Skin in Patients Exposed to Extrinsic Factors of Aging
This open-label, multi-center clinical trial was conducted to evaluate the dual skincare regimen of vitamin C serum and moisturizing sunscreen SPF 45 to improve facial hyperpigmentation and photodamage after 12 weeks of twice…
- Conditions
- Hyperpigmentation, Photodamaged Skin, Wrinkle, Fine Lines
- Trial name
- NCT05423873
- Testing
- Gentle Cleansing Lotion, Revision Skincare
- Where
- 3 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Skin Aging
Ultraformer MPT Combined With Fractional CO2 Versus Fractional CO2 Alone for Facial Rejuvenation
This pilot study compares fractional CO2 laser resurfacing alone with the same laser combined, in the same session, with micro-focused ultrasound (Ultraformer MPT) for signs of facial skin aging in women aged 50 to 65.
- Trial name
- ULTRA-CO2 (NCT07896512)
- Testing
- Ultraformer MPT, SmartXide Tetra Pro fractional CO2 laser
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Clinique Face MD