Clinical trials: Eyelid Diseases, open to volunteers
Meibomian Gland Dysfunction, Dry Eye Syndromes
Ocular Surface Changes and Meibomian Gland Dysfunction in Rheumatologic Patients
This observational study aims to assess the frequency and severity of Meibomian Gland Dysfunction (MGD) and associated ocular surface changes in patients with systemic autoimmune rheumatic diseases compared with healthy…
- Conditions
- Meibomian Gland Dysfunction, Dry Eye Syndromes, Rheumatoid Arthritis, Systemic Lupus Erythematosus
- Trial name
- NCT07810569
- Volunteers
- 150 people
- Sponsor
- Assiut University
Dry Eye, Meibomian Gland Dysfunction (Disorder)
Comparing Tear Proteomics Profile in Dry Eye Disease pre-and Post-treatment With Low Level Light Therapy
The purpose of this research study is to understand the mechanism of action of low level light therapy and also potentially yield markers associated with good treatment response.
- Trial name
- NCT07329712
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore National Eye Centre
Dry Eye, Meibomian Gland Dysfunction
Ocular Surface Health and Tear Film Stability With a Nasal Spray Dry Eye Treatment
The purpose of this study is to examine the impact of nasal spray treatment on Meibomian gland function and ocular surface health in symptomatic dry eye patients with mild to moderate Meibomian gland dysfunction (MGD).
- Trial name
- NCT07606625
- Testing
- Varenicline 0.03Mg/Spray Nasal Soln
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, Berkeley
Blepharoptosis, Device Usability
A Feedback-enabled Magnetic Device for Temporary Management of Blepharoptosis
To develop a feedback-enabled magnetic device for management of blepharoptosis and evaluate its efficacy and safety, including the gain of palpebral fissure height, visual field obstruction, blurred vision, foreign body sensation…
- Trial name
- NCT03812016
- Testing
- Feedback-enabled magnetic device
- Where
- 2 sites in Taiwan
- Volunteers
- 40 people
- Sponsor
- E-DA Hospital
Meibomian Gland Dysfunction (MGD)
Efficacy of Vevye Ophthalmic Solution for the Treatment of Meibomian Gland Dysfunction
This research study evaluates a prescription eye drop called Vevye® (cyclosporine 0.1%) for adults who have meibomian gland dysfunction (MGD), a common eye condition that can cause dry, irritated, or burning eyes.
- Trial name
- NCT07224529
- Testing
- Vevye(Cyclosporine 0.1% Ophthalmic Solution)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Alabama at Birmingham
Dry Eye Syndromes, Meibomian Gland Dysfunction
Photobiomodulation With REd vs BluE Light (REBEL)
The use of photobiomodulation or low-level light therapy (LLLT) in the ophthalmic field stemmed from dermatology which has shown impact on skin blood flow and regeneration.
- Conditions
- Dry Eye Syndromes, Meibomian Gland Dysfunction, Blepharitis
- Trial name
- NCT06371300
- Testing
- Red LLLT, Blue LLLT
- Where
- 2 sites in New Zealand, United Kingdom
- Volunteers
- 36 people
- Sponsor
- Aston University
Dry Eye, Ocular Surface Disease
Eyelid Closure in Keratometry
Cataract surgery is one of the most common performed surgeries in the world. While in the early beginnings of cataract surgery, visual rehabilitation was the main goal of the procedure, refractive outcome and subsequent relative…
- Trial name
- NCT07297849
- Testing
- Eyelid closure for 3 minutes
- Where
- Austria
- Volunteers
- 29 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Thyroid Eye Disease
Transconjunctival Versus Transcutaneous Betamethasone for Upper Eyelid Retraction in TED
This randomized controlled trial aims to compare the efficacy and safety of transconjunctival versus transcutaneous perilevator betamethasone injection in reducing upper eyelid retraction in patients with thyroid eye disease.
- Trial name
- NCT07866261
- Testing
- Betamethasone
- Volunteers
- 54 people
- Sponsor
- Assiut University
Ocular Surface Disease
Analysis of Videodermatoscopic Parameters of Ocular, Periocular, Conjunctival and Palpebral Neoformations
ANALYSIS OF VIDEODERMATOSCOPIC PARAMETERS OF OCULAR, PERIOCULAR, CONJUNCTIVAL AND PALPEBRAL NEOFORMATIONS
- Trial name
- NCT06714799
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Cataract Surgery, Ocular Infections
Efficacy of EPD-09-25 for Eyelid Hygiene Before and After Eye Surgery.
This is an interventional, open-label, two-arms clinical trial, randomized 1:1 (EPD treatment or no eyelid hygiene treatment) in patients scheduled for eye surgery (cataract surgery).
- Trial name
- NCT07418333
- Testing
- EPD Eyelid wipes
- Volunteers
- 100 people
- Sponsor
- VISUfarma SpA
Ocular Sebaceous Carcinoma, Ocular Basal Cell Carcinoma
Sentinel Lymph Node Biopsy in Ocular Surface and Adnexal Cancers
The study involves enrollment of patients with sebaceous carcinoma, Merkel's carcinoma, Porocarcinoma, Melanoma, and squamous cell Ca of the ocular surface and adnexa both primary and relapsed after surgical and/or…
- Conditions
- Ocular Sebaceous Carcinoma, Ocular Basal Cell Carcinoma, Ocular Surface Squamous Neoplasia, Merkel Cell Carcinoma, Unspecified
- Trial name
- BLS (NCT05797415)
- Testing
- Sentinel Lymph Node Biopsy
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Orbital Fractures, Orbital Floor Fractures
A Trial to Evaluate Two Ectropion Preventive Measures Using the Subciliary Approach in Orbital Fracture Surgery.
The goal of this clinical trial is to investigate whether preventive surgical techniques can reduce the incidence of lower eyelid ectropion after the subciliary approach in adult patients undergoing surgery for orbital fractures.
- Trial name
- PREVENTECT (NCT07775417)
- Testing
- Subciliary Approach, Lateral Canthopexy, Orbicularis Oculi Suspension
- Volunteers
- 30 people
- Sponsor
- Minia University
Excess Skin of Both Eyelids, Contrast Sensitivity
The Effect of Upper Blepharoplasty on Vision Quality in the Early Postoperative Period
Contrast sensitivity (CS) and tear film (TF) changes are noted in late postoperative period after upper blepharoplasty (UB), while the same was rarely investigated in the early postoperative period.
- Conditions
- Excess Skin of Both Eyelids, Contrast Sensitivity, Tear Film Insufficiency of Both Eyes, Corneal Topography
- Trial name
- NCT05549713
- Testing
- Upper blepharoplasty
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- Osijek University Hospital
Dry Eye Disease, Meibomian Gland Disease
Treating Meibomian Gland Disease in a Pediatric Population
Dry Eye Disease (DED) is commonly encountered among eye care professionals. DED is a disease of the tears and ocular surface that is multi-factorial resulting in a wide range of symptoms and signs with potentially damaging…
- Trial name
- LLLT in Peds (NCT07229001)
- Testing
- Low level light treatment, warm compress and artificial tear
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Illinois College of Optometry
Meibomian Gland Dysfunction (Disorder)
TearCare in Young Adults
This study is a non-randomized, open-label, interventional trial of TearCare® eyelid warming and manual meibomian gland expression in young adults with clinically significant meibomian gland dysfunction (MGD).
- Trial name
- NCT07579156
- Testing
- TearCare®
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Alabama at Birmingham
Dry Eye, Meibomian Gland Dysfunction (Disorder)
Low Level Light Therapy & Skin Pigmentation
The goal of this clinical trial is to determine if there is a difference in eyelid temperature after low-level light therapy (LLLT) in individuals with different amounts of skin pigmentation and dry eye/meibomian gland disease.
- Trial name
- NCT07173530
- Testing
- Three 15-minute low-level light therapy sessions using Light Emitting Diodes of wavelength 633nm (Essilor epi-c plus).
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Houston
Chalazion
Evaluation of Effectiveness and Safety of Intense Pulsed Light Treatment for Chalazion
To study the effectiveness and safety of IPL treatment for Chalazion
- Trial name
- NCT07405138
- Testing
- Active IPL
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Lumenis Be Ltd.
Pediatric Chalazia
Omega-3 Supplementation vs Demodex vs Eyelid Cleanser for Pediatric Chalazia
Participants enrolled into the study will be prescribed twice daily warm compresses for 8 weeks and randomly allocated (1:1:1) to receive either 1) Oral omega-3 supplementation and standard eyelid cleanser, 2) Anti-Demodex eyelid…
- Trial name
- CH01 (NCT07496515)
- Testing
- Omega-3 supplement, Warm compress, Standard eyelid cleanser
- Volunteers
- 168 people
- Sponsor
- Jaeb Center for Health Research
Evaporative Dry Eye Disease
Comparative Efficacy Study to Demonstrate the Non-inferiority of I-DROP® MGD Versus 2 Competitor Eye Drops in Managing Evaporative Dry Eye
A Pilot Comparative study between I-DROP MGD vs two commercially available lubricant eye drops for the management of evaporative dry eye
- Trial name
- NCT06686368
- Testing
- I-DROP MGD, Theloze Duo, Systane Complete PF
- Volunteers
- 60 people
- Sponsor
- I-MED Pharma
Dry Eye Syndromes, Meibomian Gland Dysfunction
Therapeutic Efficacy and Safety of Non-Invasive RF Treatment in Refractory MGD
The goal of this prospective, 24-week, double-masked, randomized, sham-controlled clinical trials to compare clinical efficacy and safety of RF and MGX with MGX alone in patients with meibomian gland dysfunction-related dry eye…
- Trial name
- NCT06220474
- Testing
- The Thermage FLX System
- Where
- 2 sites in Hong Kong
- Volunteers
- 112 people
- Sponsor
- The University of Hong Kong