Clinical trials: Eye Movement Disorder
Growth Hormone Deficiency, Septo-Optic Dysplasia
Endocrine Dysfunction and Growth Hormone Deficiency in Children With Optic Nerve Hypoplasia
Hypotheses: 1. The prevalence of endocrinopathies, and growth hormone (GH) deficiency in particular, among young children diagnosed with optic nerve hypoplasia (ONH) is higher than is commonly thought. 2.
- Conditions
- Growth Hormone Deficiency, Septo-Optic Dysplasia, Hypopituitarism
- Trial name
- NCT00140413
- Testing
- Nutropin AQ
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital Los Angeles
Nystagmus, Congenital Idiopathic, Nystagmus, Acquired
Efficacy and Safety Study of Neramexane to Treat Congenital and Acquired Nystagmus
The purpose of this study is to investigate the safety and efficacy of neramexane mesylate in the treatment of congenital idiopathic nystagmus (CIN) in comparison to placebo.
- Trial name
- NCT00661440
- Testing
- Neramexane mesylate
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- Merz Pharmaceuticals GmbH
Healthy Volunteer, Neurodegenerative Diseases
Visual Motor Coordination
Background: The relation between eye movement and brain function is a subject of interest to the National Eye Institute. By comparing eye movement in healthy volunteers to research conducted on patients who have difficulty moving…
- Trial name
- NCT00568243
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Esotropia
The Prism Adaptation Study (PAS)
To determine whether the preoperative use of prisms in eyeglasses can improve the outcome of surgery for acquired esotropia, a type of strabismus.
- Trial name
- NCT00000121
- Testing
- Prisms in Eyeglasses
- Sponsor
- National Eye Institute (NEI)
REM Sleep Behavior Disorder, Parkinson Disease
Efficacy and Safety of Melatonin PR and Clonazepam in Patients With REM Sleep Behavior Disorder in Parkinson Disease
The purpose of this study is to determine whether melatonin prolonged-release (PR) and clonazepam are effective and safe in the treatment of rapid eye movement behavior disorder (RBD) of patients with Parkinson's disease (PD).
- Trial name
- NCT02789592
- Testing
- Melatonin PR, Clonazepam
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Multiple System Atrophy, Parkinson Disease
Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases
This is a non-interventional observational study designed to systematically record the results of routine laryngeal examinations and specific characteristics of dysphagia in patients with neurodegenerative disorders.
- Conditions
- Multiple System Atrophy, Parkinson Disease, Progressive Supranuclear Palsy, Motor Neuron Disease
- Trial name
- FEEMSA (NCT04706234)
- Where
- 16 sites in Austria, Germany and 6 more
- Volunteers
- 350 people
- Sponsor
- Kliniken Beelitz GmbH
PSP - Progressive Supranuclear Palsy
The Progressive Supranuclear Palsy Clinical Trial Platform - Regimen A: AADvac1
The Progressive Supranuclear Palsy Clinical Trial Platform (PTP) is a multi-center, multi-regimen clinical trial evaluating the safety and efficacy of investigational products for the treatment of PSP.
- Trial name
- NCT07217665
- Testing
- AADvac1
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Adam Boxer
Concussion, Convergence Insufficiency
Interventions for Convergence Insufficiency in Concussed Children
The ICONICC Study is a randomized controlled clinical trial designed to compare the proportion of successful treatment outcomes between children assigned to standard concussion care only, standard concussion care plus simple…
- Trial name
- ICONICC (NCT03908112)
- Testing
- Standard Community Concussion Care (SC), SC plus Simple Convergence Exercises (SC+), SC plus Office-based Vergence/Accommodative Therapy (SC+OBVAT)
- Where
- 8 sites in United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Mitchell Scheiman
Amblyopia, Anisometropia
Amblyopia (Lazy Eye) Treatment Study
The purpose of this study is to compare the results of two standard treatments for amblyopia in order to find out if one is more effective than the other.
- Conditions
- Amblyopia, Anisometropia, Strabismus
- Trial name
- NCT00001864
- Testing
- Atropine, Patch
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Eye Institute (NEI)
Exotropia Equal or More Than 50 Prism Diopter
A Comparative Study Between Three Surgical Techniques in Large Angle Exotropia
This is a randomized comparative interventional study that aims to compare the surgical outcomes of correcting large angle exotropia (≥50 prism diopter) by three different surgical techniques including: 1/ bilateral lateral…
- Trial name
- NCT07143032
- Testing
- Extropia squint surgery
- Volunteers
- 60 people
- Sponsor
- Sohag University
Convergence Insufficiency
A Randomized Trial of Base-in Prism Reading Glasses Convergence Insufficiency in Children
This study is designed to compare the use of special prism glasses to placebo treatment for children with symptomatic convergence insufficiency.
- Trial name
- NCT00347581
- Testing
- Base-in prism glasses for reading
- Where
- 10 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Pennsylvania College of Optometry
TBI (Traumatic Brain Injury), Ocular Motility Disorders
Frontoparietal Priority Maps as Biomarkers for MTBI
The purpose of this study is to determine whether there is a quantitative relationship between brain processes seen by a MRI and visual deficits caused by mild to moderate traumatic brain injuries (mTBI).
- Trial name
- NCT02251002
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Strabismic Deviation, Strabismus
Botulinum Toxin for Strabismus Treatment
The bacterial species Clostridium botulinum produces a class of neurotoxins known as botulinum toxin. At the neuromuscular junction, botulinum toxin A prevents acetylcholine from being released.
- Trial name
- Botox Squint (NCT07180394)
- Testing
- Botox injection into extraocular muscles
- Where
- Pakistan
- Volunteers
- 127 people
- Sponsor
- Foundation University Islamabad
Strabismus
Anesthetic Depth and the Incidence of Emergence Agitation in Children Undergoing Strabismus Surgery
This study evaluates the association between the depth of general anesthesia and the occurrence of emergence agitation (EA). The investigators hypothesized that optimal level of anesthetic depth could decrease the incidence of EA…
- Trial name
- NCT02521259
- Testing
- BIS
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Seoul National University Bundang Hospital
Amblyopia, Strabismus
Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner
The purpose of this project is to compare the performance of the Pediatric Vision Scanner (PVS) with the Gold Standard Examination to determine the effectiveness of the PVS at detecting amblyopia and strabismus.
- Trial name
- NCT01726842
- Testing
- Pediatric Vision Scanner
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Alcohol Use Disorder, Alcohol Craving
Eye Movements Desensitization and Reprocessing Intervention in Preventing Craving in Alcohol Use Disorder
This study is conducted to examine the effect of a psychotherapy model that is expected to affect alcohol cravings in adults aged 18-65 years who are being treated for alcohol use disorder at a clinic.
- Trial name
- NCT05606900
- Testing
- addiction-focused eye movements desensitization and reprocessing (AF-EMDR)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ege University
Exercise Training, Intermittent Exotropia
Exercise Training on a Mirror for Intermittent Exotropia Control Post Strabismus Surgery
The study aims to explore the impact of mirror therapy on exodeviation control, near and far strabismus angles, and quality of life in intermittent exotropia control post strabismus surgery, as well as its effects on near and far…
- Conditions
- Exercise Training, Intermittent Exotropia, Strabismus
- Trial name
- NCT06762067
- Testing
- mirror therapy, traditional therapy
- Volunteers
- 40 people
- Sponsor
- Cairo University
Macular Disease
Translation of Eye Movement Reading Training to Clinical Practice
Age-related macular degeneration (AMD) is the most common visual impairment in persons over 50 years of age. It has been estimated that 1 in 3 individuals over 75 years of age and 1 in 30 individuals over 52 years of age are…
- Trial name
- NCT01853930
- Testing
- Platform for Administering Eye-movement Control Training
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Presbyopia, Esotropia
Accommodation-Related Visual Training Combined with Transcranial Electrical Stimulation Versus Visual Training Alone for the Treatment of Accommodation Dysfunction
This is a single-center, randomized controlled trial to compare the effectiveness of transcranial electrical stimulation combined with visual training with visual training alone for the treatment of accommodation disorder…
- Trial name
- NCT06714890
- Testing
- Transcranial Electrical Stimulation, Visual Training
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Major Depressive Disorder, Bipolar Disorder
An Eye Tracking Study of Affective Disorder Patients With Suicide Risk
This research tries to investigate the validity and reliability of eye-tracking technologies by using different paradigms (eg. free-view, pro-saccade and anti-saccade) which served as a novel way of evaluating suicide risk among…
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Suicide
- Trial name
- NCT03711045
- Testing
- eye-tracking
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central South University