Clinical trials: Extremity Injury
Athletic Injuries
Validity of an Upper Extremity Physical Performance Test Battery in Healthy Athletes
This project comprises two studies; a cross-sectional study and a prospective study. 1. The cross-sectional study aims to develop and validate a new sport-specific test battery (PROMs, analytical and physical performance tests)…
- Trial name
- VAL_PPT_H (NCT06153121)
- Testing
- Physical performance test - Closed Kinetic Chain Upper Extremity Stability Test (CKCUEST), Physical performance test - modified Closed Kinetic Chain Upper Extremity Stability Test (m-CKCUEST), Physical performance test - Seated Seated Single Arm Shot Put Test (SSASPT)
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Ghent
Postoperative Pain, Arm Injury
Plasma Concentration of Somatostatin and Endocannabinoids After GA and RA in Upper Extremity Trauma Surgery
The application of RA can decrease the central sensitization and chronic pain after trauma surgery. The plasma concentrations of somatostatin and fatty acid amides were not studied up to this time in this kind of settings, so…
- Trial name
- SECsGRUES (NCT04040738)
- Testing
- Upper extremity surgery under general anaesthesia, Upper extremity surgery under regional anaesthesia
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- University of Pecs
Stroke, Multiple Sclerosis
Upper Limb Muscle Strength Models for Patients With Motor Impairment.
Upper limb motor impairments are common. They affect quality of life and can lead to dependency. They are mainly due to neurological conditions such as stroke, multiple sclerosis, and traumatic spinal cord injury.
- Conditions
- Stroke, Multiple Sclerosis, Spinal Cord Injuries
- Trial name
- MusMapS (NCT06608121)
- Testing
- Upper limb isokinetic forces measurements
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Pôle Saint Hélier
Soft Tissue Injuries
Cost-effectiveness of Two Painkillers for Treating Pain After Limb Injuries
Background: Paracetamol and non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen are commonly used oral analgesics in emergency departments (ED) not only in Hong Kong but throughout the world.
- Trial name
- NCT00528658
- Testing
- Paracetamol, Ibuprofen
- Where
- Hong Kong
- Volunteers
- 782 people
- Sponsor
- Chinese University of Hong Kong
Degenerative Arthritis of Left Glenohumeral Joint, Degenerative Arthritis of Right Glenohumeral Joint
Costs and Consequences of Three Common Orthopedic Procedures on the Upper Extremity
This study compares costs and effectiveness / utility of three common orthopedic surgeries in shoulder and hand from the perspective of the Swiss health system and the clinic.
- Conditions
- Degenerative Arthritis of Left Glenohumeral Joint, Degenerative Arthritis of Right Glenohumeral Joint, Rotator Cuff Tear Arthropathy, Rotator Cuff Tear
- Trial name
- NCT01954433
- Testing
- Operated TSA Patients, Operated RCR Patients, Resection interposition suspension arthroplasty (RISA)
- Where
- Switzerland
- Volunteers
- 450 people
- Sponsor
- Schulthess Klinik
Pain, Traumatic Limb Injury
Pre-hospital Care With Intra-Nasal Ketamine for Transport (PRECINKT): A Pilot Study
The investigators hypothesize that intra-nasal ketamine, for analgesia of patients with moderate to severe pain in an alpine setting, will provide a clinically significant reduction in pain and provide an effective and feasible…
- Trial name
- PRECINKT (NCT02033434)
- Testing
- Intranasal Ketamine
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Lower Limb Amputation, Prosthesis Users
Dual-Task Balance Training in Traumatic Lower-Limb Prosthesis Users
This randomized controlled trial will evaluate the effectiveness of dual-task balance training on balance, mobility, and mental health among traumatic lower-limb prosthesis users in the Gaza Strip.
- Conditions
- Lower Limb Amputation, Prosthesis Users, Balance Impairment, Mobility Limitations
- Trial name
- DTBT-LLA (NCT07706452)
- Testing
- Dual-Task Balance Training, Standard Rehabilitation
- Where
- Palestinian Territories
- Volunteers
- 63 people
- Sponsor
- Al-Azhar University - Gaza
Traumatic Brain Injury, Weakness, Muscle
Physical and Mental Practice for Bimanual Coordination Rehabilitation
Traumatic Brain Injury (TBI)patients often suffer from loss of muscle strength in the hand and foot, decrease in coordination and high muscle tone (spasticity).
- Conditions
- Traumatic Brain Injury, Weakness, Muscle, Coordination Impairment
- Trial name
- NCT03817086
- Testing
- Hand coordination and mental practice, Hand coordination and action observation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Kessler Foundation
Extremity Orthopedic Surgery
Perioperative Cardiac Troponin Levels in Healthy Adults
This study will determine the extent of high-sensitivity cardiac troponin (hs-cTn) release in patients without cardiac risk factors undergoing extremity orthopedic surgery.
- Trial name
- NCT02394288
- Testing
- Extremity orthopedic or trauma surgery
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- Medical University of Vienna
Vascular Disease, Peripheral, Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)
Correlating Multispectral Near-Infrared Imaging to Standard Vascular Diagnostics
The goal of this observational study is to learn if the measures of tissue oxygenation from the MIMOSA Pro imaging device correlate to standard vascular assessment tools in patients who receiving a lower extremity vascular…
- Trial name
- NCT06899113
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- MIMOSA Diagnostics Inc.
Concussion, Mild
Multimodal Approach to Testing the Acute Effects of Mild Traumatic Brain Injury (mTBI)
The objective of the study is to determine the relative roles for various testing modalities in the diagnosis and prognosis of mild traumatic brain injury.
- Trial name
- NCT02069613
- Where
- 3 sites in United States
- Volunteers
- 44 people
- Sponsor
- Huntington Medical Research Institutes
Burned
Isokinetic Training Versus Treadmill Training on Muscle Strength and Gait in Children With Lower Limb Burns
Burn wounds are one of the most complexes and dramatic of all injuries, it produces a direct local tissue destruction and damage.
- Trial name
- NCT06036082
- Testing
- Conventional physical therapy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- South Valley University
Lower Limb; Fusion, Congenital, Lower Limb Fracture
Investigating Auto Adjusting Dynamic AFO
Offloading Ankle Foot Orthoses (AFOs) are devices designed for people following lower-limb reconstruction to restore mobility by reducing mechanical loading through the injury site and redistributing it proximally.
- Conditions
- Lower Limb; Fusion, Congenital, Lower Limb Fracture, Ankle Foot Injury
- Trial name
- NCT04623853
- Testing
- Variable Stiffness AFO
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Washington
Distal Radius Fracture
Surgical Field Quality Assessment and Complications in Distal Radius Fractures Using the Minimum Inflation Tourniquet Pressure.
Analyse surgical field bleeding, surgical time, and intraoperative pain in patients undergoing osteosynthesis of distal radius fractures using ischaemia pressure calculated based on Limb Occlusion Pressure, compared with Arterial…
- Trial name
- NCT07318194
- Testing
- PNEUMATIC TOURNIQUET INFLATION PRESSURE
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Consorci Sanitari de Terrassa
Musculoskeletal Injury, Spinal Injuries
Predictive Models for Spine and Lower Extremity Injury After Discharge From Rehab
The purpose of this study is to develop algorithms that will help predict future injury and/or re-injury after being returned to duty from a musculoskeletal injury.
- Conditions
- Musculoskeletal Injury, Spinal Injuries, Leg Injuries
- Trial name
- MP3-RD (NCT02776930)
- Where
- 4 sites in United States
- Volunteers
- 480 people
- Sponsor
- Brooke Army Medical Center
Thrombosis, Injury Leg
Thromboprophylaxis in Lower Limb Immobilisation
The goal of this clinical trial is to find out the clinical and cost effectiveness of Thromboprophylaxis in participants who have been placed in a plaster cast or splint after injury.
- Trial name
- TiLLI (NCT06370273)
- Testing
- Rivaroxaban, Apixaban, Enoxaparin Injectable Solution
- Where
- 5 sites in United Kingdom
- Volunteers
- 10,044 people
- Sponsor
- Queen Mary University of London
Burns
Early Versus Late Upper Extremity Mobilization After Meshed / Sheet Split Thickness Skin Autograft on Wound Healing in Adult Burn Patients
STSGs are used to close wounds and minimize infections. After receiving a meshed or sheet split-thickness skin graft (STSG) to the upper extremity or hand for a thermal burn injury, burn surgeons use different methods to improve…
- Trial name
- EXTREMA (NCT06143683)
- Testing
- Early Mobilization, Late Mobilization
- Volunteers
- 100 people
- Sponsor
- Hamilton Health Sciences Corporation
Endothelial Dysfunction
Artery Function Responses to Heat Therapy and Exercise Training
This study will explore the effects of 8 weeks of local leg heat therapy, exercise training, or both on measures of vascular function, cardiorespiratory fitness, and muscle strength in young, healthy individuals.
- Trial name
- NCT04588103
- Testing
- Heat therapy, Exercise training
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McMaster University
Fractures, Bone, Nausea and Vomiting, Postoperative
Quality of Recovery After Dexamethasone, Ondansetron or Placebo Intrathecal Morphine Administration
The aim of this study is to evaluate not only the occurrence of side effects, but the quality of the recovery (QoR-40 Questionnaire) of patients submitted to spinal anesthesia with administration of low doses (0.1 mg) of…
- Conditions
- Fractures, Bone, Nausea and Vomiting, Postoperative, Pruritus, Morphine Adverse Reaction
- Trial name
- NCT03035942
- Testing
- Dexamethasone, Ondansetron, Saline
- Where
- Brazil
- Volunteers
- 135 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Amputation, Traumatic, Prosthesis User
Evaluation of a Non-invasive Sensory Feedback System in Hand Prostheses
Implication and evaluation of a non-invasive sensory feedback system in hand prostheses in everyday life.
- Trial name
- NCT03876405
- Testing
- smartskin non-invasive sensory feedback
- Volunteers
- 7 people
- Sponsor
- Lund University Hospital