Clinical trials: Experimental
Aphasia, Acquired, Stroke, Acute
Neolexon® Aphasia-App in Acute Aphasia After Stroke
Up to now there is proven evidence of traditional logopedic therapy in aphasia, but recent computer-based algorithms also showed their evidence so far.
- Trial name
- Lexi (NCT04080817)
- Testing
- Neolexon, Speech therapy, Self training
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Alzheimer's Disease
Safety and Efficacy Study Evaluating Dimebon in Patients With Mild to Moderate Alzheimer's Disease on Donepezil
The purpose of this study is to determine if Dimebon is safe and effective in patients with mild to moderate Alzheimer's disease on Donepezil.
- Trial name
- CONCERT (NCT00829374)
- Testing
- Dimebon
- Where
- 101 sites in United States, Australia and 8 more
- Volunteers
- 1,003 people
- Sponsor
- Medivation, Inc.
Nurse's Role
Improving the Endotracheal Tube Cuff Pressure Control Knowledge
This study aimed to evaluate how an educational intervention based on the existing evidence-based guidelines, using both active and passive educational implementetion strategies, could improve the knowledge of nurses regarding…
- Trial name
- NCT05797844
- Testing
- Active implementational educational strategy, Passive implementational educational strategy
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Colon Cancer, Rectal Cancer
A Study of Ramucirumab or Icrucumab in Colorectal Cancer
The purpose of this study is to determine if participants with metastatic colorectal cancer live longer without their cancer progressing when treated with standard chemotherapy, standard chemotherapy plus ramucirumab, or standard…
- Trial name
- NCT01111604
- Testing
- Ramucirumab, Icrucumab, mFOLFOX-6
- Where
- 17 sites in United States, Canada
- Volunteers
- 158 people
- Sponsor
- Eli Lilly and Company
Surgery
Evaluation of Coaching Impact on Surgical Outcomes
This two arms parallel cluster-randomized trial will evaluate the impact of a customized coaching program for surgeons on the occurrence of patient major adverse events.
- Trial name
- TopSurgeons (NCT04532658)
- Testing
- Coaching program
- Where
- France
- Volunteers
- 20,791 people
- Sponsor
- Hospices Civils de Lyon
Sleep Disorder
Sleep Hygiene Intervention on Sleep Quality Improvement in Elders With Parkinson's Disease
Sleep disorders (SDs) are one of the most frequent non-motor symptoms of Parkinson's disease (PD), usually increasing in frequency over the course of the disease and disability progression.
- Trial name
- NCT06937632
- Testing
- sleep hygiene intervention
- Where
- Egypt
- Volunteers
- 136 people
- Sponsor
- Alexandria University
Wrinkles
Single-Blind, Investigational Device Exemption Paired-Design, Non-Inferiority Trial With Confirmation for the Assessment of the Efficacy and Safety of a Universal Electrosurgical Device for Temporary Improvement of Mild and Moderate Wrinkles Around Both Eye Corners and Both Cheek Folds
Radiofrequency (RF) devices are commonly used for noninvasive facial rejuvenation. This study compared the efficacy and safety of 10THERMA, a newly developed monopolar RF device, with those of the Thermage FLX system.
- Trial name
- NCT07467811
- Testing
- 10THERMA, Thermage FLX
- Where
- 3 sites in South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- TENTECH INC.
Irritable Bowel Syndrome
Effects of Standardized Boswellia Carterii Extract on Irritable Bowel Syndrome Patients
Irritable bowel syndrome (IBS) is a common condition that affects the stomach and intestines. It can cause abdominal pain, bloating, diarrhea, constipation, and changes in bowel habits, which may reduce a person's quality of…
- Trial name
- BC-IBS (NCT07576634)
- Testing
- Boswellia carterii Extract, Educationntal program for IBS patie
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Tumors
NB1011 Administered by Continuous Infusion in Cancers That Overexpress Thymidylate Synthase (TS)
The purpose of this trial is to assess the tolerability and safety of NB1011 in the treatment of patients with cancers that overexpress TS, such as ovarian, gastrointestinal, colorectal, bladder, breast, and lung cancers.
- Trial name
- NCT00248404
- Testing
- NB1011
- Where
- 3 sites in United States, Canada
- Volunteers
- 155 people
- Sponsor
- Kiadis Pharma
On-pump Cardiac Surgery - Prevention - Intervention - Experimental Group - Control Group - Incidence - Complications, DVT - Deep Vein Thrombosis
This Research Proposal Focuses on Evaluating the Effectiveness of a Nursing Care Protocol in Preventing Deep Vein Thrombosis (DVT) in Patients Undergoing On-pump Cardiac Surgery. The Study Will Include an Intervention Group That Receives the Nursing Protocol and a Control Group That Receives Routine
The primary focus of this research proposal is to examine the efficacy of a nursing care protocol in preventing the occurrence of deep vein thrombosis (DVT) in patients undergoing on-pump cardiac surgery.
- Conditions
- On-pump Cardiac Surgery - Prevention - Intervention - Experimental Group - Control Group - Incidence - Complications, DVT - Deep Vein Thrombosis, DVT Prophylaxis, DVT Prevention
- Trial name
- DVT (NCT07347652)
- Testing
- IPC devices facilitate venous return by simulating the physiological effects of muscle contraction, reducing venous stasis.
- Where
- Cyprus
- Volunteers
- 67 people
- Sponsor
- Near East University, Turkey
Colon Cancer, Inflamatory Bowel Disease (Crohn's and Ulcerative Colitis)
Effectiveness of Health Education as a Nursing Intervention in Improving Quality of Life and Reducing Symptoms of Anxiety and Depression in Ostomy Patients Following Digestive Surgery: A Quasi-Experimental Study.
The proposed project is a prospective quasi-experimental study to be conducted at the Ostomy Clinic of the University Hospital Complex of Santiago de Compostela.
- Conditions
- Colon Cancer, Inflamatory Bowel Disease (Crohn's and Ulcerative Colitis), Colitis Ulcerative
- Trial name
- NCT07347158
- Testing
- Health Education
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Hearing Loss, Cochlear
Effects of Pulses on Loudness
The aim of this study is to investigate the effect of varying additional factors on loudness summation in Neuro Zti Cochlear Implant users.
- Trial name
- EfPuL (NCT04010721)
- Testing
- Experiment 1, Experiment 2:, Experiment 3
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Oticon Medical
Pain
Non-pharmacological Pain Management in Term Neonates
A randomised clinical trial in a single centre. This study was performed to compare the effect of white noise, facilitated tucking, and their concerted application during heel-stick sampling on pain in term babies.
- Trial name
- NCT04144543
- Testing
- White Noise, Facilitated Tucking, White Noise+Facilitated Tucking
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Psoriasis
Assessment of Gut Absorption of Experimental Medication BMS-986165 in Healthy Males
The purpose of this study is to evaluate sites of gut absorption of BMS-986165 in males
- Trial name
- NCT03873415
- Testing
- BMS-986165
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Urticaria, Autoimmune Diseases
Experimental Autologous Mesenchymal Stem Cell Therapy in Treatment of Chronic Autoimmune Urticaria
The aim of this study is to determine whether autologous adipose tissue derived Mesenchymal Stem Cells of treatment for chronic autoimmune urticaria is safe and effective.
- Conditions
- Urticaria, Autoimmune Diseases, Immune System Diseases, Skin Diseases
- Trial name
- NCT02824393
- Testing
- Autologous mesenchymal stem cell
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Manisa Celal Bayar University
Chronic Neck Pain
Effects of Minimally Invasive Techniques in Healthy and Chronic Cervical Pain Individuals
Brief Summary: This project consists of two sequential experimental phases designed to analyze the immediate and 24-hour effects of three invasive physiotherapy techniques -dry needling (DN), percutaneous neuromodulation (PENS)…
- Trial name
- NCT07345793
- Testing
- Dry needling, Percutaneous nerve stimulation, Percutaneous electrolysis
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Stomatitis
Effectiveness of Hygiene Solutions on Denture Biofilm
This clinical trial evaluated Ricinus communis and sodium hypochlorite solutions in different concentrations for denture cleanliness, regarding biofilm removal capacity, remission of atrophic chronic candidiasis, degree of…
- Trial name
- NCT02407834
- Testing
- S1, S2, S3
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Toe Walking Behaviors, Backward Walking
Backward Walking Effects on Toe Walking in a Child With ASD: Single-Case Study
This study tested the hypothesis that backward walking exercises can reduce Toe Walking Behaviors (TWB) in children with ASD and emphasized the importance of pedobarographic measurements for quantitative TWB assessment.
- Trial name
- NCT07078214
- Testing
- Foot Sole Surface Area Measurements, Walking Exercise Program and Implementation Process
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Giresun University
Hemophilia A, Hemophilia B
Safety and Effectiveness of Giroctocogene Fitelparvovec or Fidanacogene Elaparvovec in Patients With Hemophilia A or B Respectively
A study to learn about the long-term safety and efficacy of giroctocogene fitelparvovec or fidanacogene elaparvovec in patients with hemophilia A or hemophilia B respectively, who have received treatment through prior…
- Trial name
- NCT05568719
- Testing
- Testing of hepatic AAV Vector integration
- Where
- 39 sites in United States, Australia and 11 more
- Volunteers
- 173 people
- Sponsor
- Pfizer
HIV Infections
Evaluating the Safety, Tolerability, and Pharmacokinetics of an Investigational, Injectable HIV Medicine (GSK1265744) in HIV-Uninfected Adults
This study will evaluate the safety, tolerability, and pharmacokinetics (which is how the body interacts with drugs) of an investigational, injectable HIV medicine (GSK1265744) in healthy, HIV-uninfected adults.
- Trial name
- NCT02178800
- Testing
- GSK1265744 Tablets, Injectable GSK1265744
- Where
- 8 sites in United States, Brazil and 2 more
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)