Clinical trials: Exhaustion Disorder
Depression, Anxiety
A Comprehensive Wellness Program (SKY) to Mitigate Physician Burnout
The primary objective of the study was to determine whether the yoga-based breathing and meditation program SKY could improve wellness indicators in currently practicing physicians.
- Conditions
- Depression, Anxiety, Stress, Insomnia
- Trial name
- SKY (NCT05956470)
- Testing
- Meditation and breathing program : Sudarshan Kriya Yoga (SKY), Stress management education
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Heart Rate Variability, Burnout
Helping Overcome Pressure and Exhaustion: Empowerment Classes for Southeast Asian Migrant Care Workers
As Taiwan's population ages, Southeast Asian migrant care workers are widely employed to fill the care labor gap. These workers often face symptoms of burnout and emotional stress due to long working hours and high-pressure…
- Conditions
- Heart Rate Variability, Burnout, Depression
- Trial name
- HOPE (NCT06532305)
- Testing
- HOPE empowerment classes
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Chronic Fatigue Syndrome
Exertional Exhaustion in Chronic Fatigue Syndrome
Post-exertional malaise was modeled by having Chronic Fatigue Syndrome (CFS) and sedentary control subjects perform submaximal exercise on 2 consecutive days with objective changes in brain function measured by magnetic resonance…
- Trial name
- NCT03567811
- Testing
- Submaximal bicycle exercise stress test on Days 1 and 2
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Cardiovascular Diseases Risk
Circulating Vascular Regenerative Cell Exhaustion in Individuals Without Type 2 Diabetes Who Are of South Asian or European Origins
ORIGINS-VRCE-2 is an observational study aimed to assess how blood vessel forming stem cells from individuals without diabetes or a history of cardiovascular disease differ between individuals of South Asian and European…
- Trial name
- ORIGINS-VRCE-2 (NCT06769347)
- Where
- 5 sites in Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Canadian Medical and Surgical Knowledge Translation Research Group
Heat Cramps, Heat Rash
Testing Interventions to Mitigate the Health Impact of Heatwaves on Primary School Children in Climate-vulnerable Districts of Bangladesh.
The goal of this clinical trial is to assess the impact of implementing a combination of heat education and school-based physical infrastructure interventions in reducing heat related illnesses and improving educational outcomes…
- Conditions
- Heat Cramps, Heat Rash, Heat Exhaustion, Heat Stress
- Trial name
- NCT07877935
- Testing
- Solar reflective paint, Bamboo ceiling with polyethylene foam, Heat education toolkit
- Where
- 2 sites in Bangladesh
- Volunteers
- 2,875 people, healthy volunteers welcome
- Sponsor
- BRAC University
Fatigue Syndrome, Chronic, Inflammation
Evaluation of the Effects of Treatment With Bioarginin C in Adult Subjects Belonging to the Post-Covid Day Hospital
Long Covid could be much more frequent than it is thought to be. Few dwell on the great problem represented by the post covid syndrome.
- Trial name
- BC (NCT04947488)
- Testing
- Bioarginina C
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Milan
Burnout, Professional, Emotional Exhaustion
The INSPIRE Study: INvestigation of Swiss Physicians Inner-life, Resilience, and Emotions
The goal of this clinical trial, nested within an observational cohort study, is to evaluate whether two positive psychology web-based interventions can reduce emotional exhaustion and improve overall well-being in practicing…
- Conditions
- Burnout, Professional, Emotional Exhaustion, Emotions, Wellness, Psychological
- Trial name
- INSPIRE (NCT06806150)
- Testing
- INSPIRE Life Reflection, INSPIRE Work Reflection
- Where
- Switzerland
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Bern
Polycystic Ovary Syndrome
Pro-vascular Regenerative Cell Exhaustion in Women With Polycystic Ovarian Syndrome
PCOS-RCE is an observational, cross-sectional, two-arm study that is aimed at determining if an established diagnosis of polycystic ovarian syndrome (PCOS) influences the number of blood vessel-forming stem cells in the…
- Trial name
- PCOS-RCE (NCT05410834)
- Where
- 3 sites in Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Canadian Medical and Surgical Knowledge Translation Research Group
Horticultural Therapy, Anxiety
The Effect of Horticultural Therapy on Mental Health and Burnout Levels of Nursing Home Workers
The incidence of people with disabilities in need of care services is increasing all over the world. This situation significantly increases the need for nursing homes and caregivers.
- Conditions
- Horticultural Therapy, Anxiety, Depression, Stress
- Trial name
- NCT06484959
- Testing
- Assigned Interventions
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Peripheral Vascular Diseases, Cardiovascular Disease
Vascular Regenerative Cell Exhaustion in Adults With Peripheral Artery Disease (PAD-VRCE)
PAD-VRCE is an observational, cross-sectional, two arm study aimed at determining if the presence of peripheral artery disease (PAD) can influence the number of circulating regenerative cells in blood.
- Conditions
- Peripheral Vascular Diseases, Cardiovascular Disease, Type 2 Diabetes, Peripheral Artery Disease
- Trial name
- PAD-VRCE (NCT06626646)
- Where
- 2 sites in Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Canadian Medical and Surgical Knowledge Translation Research Group
Iron Deficiencies, Low Ferritin
A Pilot Study to Evaluate the Ability of Lactoferrin to Modulate Iron Homeostasis and Exercise Performance in Exercising Females
This randomized, double-blind, active-controlled trial will evaluate the effects of human lactoferrin supplementation combined with low-dose iron on iron status, aerobic performance, and lactate metabolism in exercising women…
- Conditions
- Iron Deficiencies, Low Ferritin, Iron Deficiency, Exercise Performance of Fit Athletes
- Trial name
- EFF (NCT07546591)
- Testing
- Lactoferrin 100 mg, Lactoferrin 300 mg, Iron Supplementation (5 mg)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Chronic Hepatitis B
Targeting ANKRD11 Reverses HBV-Specific CD8+ T Cell Dysfunction and Tolerance
Achieving a functional cure for chronic hepatitis B (CHB) is largely hindered by the irreversible functional exhaustion and immune tolerance of hepatitis B virus (HBV)-specific CD8 positive T (CD8+ T) cells.
- Trial name
- NCT07777250
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beijing Municipal Administration of Hospitals
Melanoma
Pembrolizumab Effects on NK Cell Exhaustion in Melanoma (Merck NK-IIT)
Melanoma is an immune-modulated malignancy and immune checkpoint modulators which inhibit PD-1 function (pembrolizumab, nivolumab) have demonstrated clinical efficacy as treatment for patients with stage IV melanoma.
- Trial name
- NCT03241927
- Testing
- Pembrolizumab
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Nina Bhardwaj
Fibromyalgia, Irritable Bowel Syndrome
Patient-reported Outcome Measures (PROMs) in Patients With Bodily Stress Syndrome: Protocol for a Prospective Cohort Study
This cohort study implements patient reported outcome measures (PROMs) for patients with bodily stress syndrome in a clinic for functional disorders.
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Somatic Symptom, Chronic Fatigue Syndrome
- Trial name
- SYMPA (NCT04667611)
- Testing
- Psychosocial interventions
- Where
- Finland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Heat Stroke, Heat Exhaustion
Chemical Ice Packs for Cooling Hyperthermic Patients
A common tool to cool people in the pre-hospital setting is the chemical ice pack. These are used by athletic trainers, EMS personnel, ER staff, and people in the prehosoital setting.
- Trial name
- NCT01694290
- Testing
- Chemical Cold Pack
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Stanford University
COVID-19
Exhaustion and Needs in Frontline COVID-19 Healthcare Workers: Cross-sectional Study in a Belgian Population
Background: In the Covid-19 pandemic context, all healthcare teams face clinical, organizational and technical challenges given the contagion, severity and mortality characteristics of the disease.
- Trial name
- NCT04344145
- Where
- 5 sites in Belgium
- Volunteers
- 693 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles
Diabetes Mellitus, Type 2
Functional Investigation of Endothelial Function and Regenerative Cell Exhaustion
FIERCE is an observational cross-sectional study. Approximately 90 individuals living with type 2 diabetes (T2D) and/or individuals living without diabetes will be randomized (2:1).
- Trial name
- FIERCE (NCT06108388)
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Canadian Medical and Surgical Knowledge Translation Research Group
Exhaustion; Syndrome
Effects of Acute Physical Activity in Patients With Exhaustion Disorder
A new stress-related diagnosis, Exhaustion disorder (ED), was introduced in the Swedish version of ICD-10 in 2005 and has since then increased rapidly.
- Trial name
- NCT06429423
- Testing
- Acute exercise low intensity, Acute exercise moderate intensity
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Victoria Blom
Burnout, Professional, Caregiver Exhaustion
Effect of Implementation of a Moral Case Delibration Meetings on the Prevalence of Burn-out Syndrome in the ICU
Burnout syndrome (BOS) has a high prevalence in critical care nurses and physicians. Both personal characteristics and work-related factors have been associated with BOS.
- Trial name
- MCDIC (NCT04442438)
- Testing
- Monthly moral case deliberation
- Where
- 2 sites in Netherlands
- Volunteers
- 435 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Immune System Diseases, COVID-19 Vaccine Adverse Reaction
COVID-19 Post-Vaccination Observation
The study started after the second COVID-19 vaccination of the participant with blood spots appearing on the skin with severe arthritis.
- Conditions
- Immune System Diseases, COVID-19 Vaccine Adverse Reaction, Immune System Disorder
- Trial name
- NCT06107348
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Yang I. Pachankis, PhD