Clinical trials: Exhaled Breath Condensate
Cystic Fibrosis
Breath Condensate Study in Patients With Cystic Fibrosis.
There is an urgent need for a noninvasive method to diagnose bronchial infections and exacerbations in patients with Cystic Fibrosis (CF).
- Trial name
- NCT02056132
- Testing
- Exhaled Breath Condensate
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Florida
Asthma, Vitamin D Resistant Rickets
Assessment Of Vitamin D Role In The Pathogenesis Of Asthma In Vitamin D Resistent Patients
Research Title: Evaluation of airway reactivity, allergy and inflammatory mediators in exhaled breath condensate in vitamin D resistant rickets.
- Trial name
- NCT01578824
- Testing
- Methacholine Challenge Test
- Where
- Israel
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Inflammatory Response, Immunological Abnormality
Measurment of Interleuukin-6 at Exhaled Breath Condensate of Covid-19 Patients and Post Covid-19 Patients With Lung Fibrosis Randomized Controlled Study
COVID-19 has emerged as a global pandemic. It is mainly manifested as pneumonia which may deteriorate into severe respiratory failure.
- Conditions
- Inflammatory Response, Immunological Abnormality, COVID-19
- Trial name
- NCT05157204
- Testing
- measurment of interleukin-6 at exhaled condensate
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Saudi Arabia
Cystic Fibrosis, Healthy
Utilizing Exhaled Breathe Condensate Collection to Study Ion Regulation in Cystic Fibrosis
Our aims were to determine if exhaled breath condensate (EBC) could detect differences in ion regulation between cystic fibrosis (CF) and healthy and measure the effect of the albuterol on EBC ions in these populations.
- Trial name
- NCT01880723
- Testing
- Albuterol
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Air Pollution Exposure, Oxidative Stress
Savannah Environmental Nutrition Study (SENS): Nutrition Intervention to Reduce Air Pollution-Related Airway Inflammation and Oxidative Stress
This pilot clinical trial will evaluate the feasibility and potential health effects of a nutrition-based intervention among adults living in communities affected by air pollution near the Port of Savannah, Georgia.
- Conditions
- Air Pollution Exposure, Oxidative Stress, Airway Inflammation
- Trial name
- NCT07797413
- Testing
- Antioxidant- and Nutrient-Rich Food-Based Nutrition Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Georgia Southern University
Lung Cancer
Serum and Exhaled Breath Condensate MALDI-MS of Lung Cancer. (SPORE)
RATIONALE: Collecting and storing samples of blood and exhaled breath from patients with cancer and from healthy participants to study in the laboratory may help doctors learn more about changes that occur in DNA and identify…
- Trial name
- NCT00898209
- Testing
- protein expression analysis, proteomic profiling, biologic sample preservation procedure
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Asthma, Healthy
Inflammatory Markers in Exhaled Breath (Condensate) in Childhood Asthma
Background: Exhaled nitric oxide and inflammatory biomarkers in exhaled breath condensate may be useful to diagnose and monitor childhood asthma.
- Conditions
- Asthma, Healthy, Children
- Trial name
- NCT00404976
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obstructive Sleep Apnea, Inflammation
A Community Study of the Risk for Obstructive Sleep Apnea and Respiratory Inflammation in an Adult Chinese Population
We aimed to investigate the relationship between obstructive sleep apnea (OSA) risk and respiratory inflammation evaluated by the exhaled breath condensate （EBC）interleukin-6 IL-6 and plasma SP-D, based on the Berlin…
- Conditions
- Obstructive Sleep Apnea, Inflammation, Exhaled Breath Condensate, Surveys and Questionnaires
- Trial name
- NCT04832711
- Where
- China
- Volunteers
- 1,270 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Proof Of Concept Study
Measuring Hydrogen Peroxide in Exhaled Breath Condensate in HV
The purpose of this study is to evaluate the performance of an Exhaled Breath Condensate (EBC) device. EBC measurements can be used for the assessments of lung inflammation in asthma and chronic obstructive pulmonary disease…
- Trial name
- NCT05844553
- Testing
- Measurement of inhaled measuring hydrogen peroxide in exhaled breath
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Carboxyhemoglobin, Vital Signs
Evaluation of the Acute Effect of Water-Pipe Smoking on the Respiratory System
Title: The acute effect of water pipe smoking on exhaled nitric oxide (eNO) and exhaled breath condensate (EBC) pulmonary function tests in healthy volunteers Objectives: To evaluate the acute effect of one cession of water pipe…
- Conditions
- Carboxyhemoglobin, Vital Signs, Fractional Exhaled NO, Exhaled Breath Condensate
- Trial name
- NCT01157832
- Where
- 2 sites in Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Combined Allergic Rhinitis and Asthma Syndrome
Exhaled Breath Condensate Biomarkers in CARAS
To explore the differences in the expression of biomarkers in different sample types between the healthy population and different subgroups of the disease, and to screen for potential biomarkers in a more simple, direct and…
- Trial name
- NCT06573450
- Testing
- questionnaire survey
- Where
- China
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Henan University of Traditional Chinese Medicine
Lung Cancer (Diagnosis), Lung Cancer (Suspected or Confirmed)
A Study Measuring Markers of Airway Inflammation in Breath Samples From People With Respiratory Diseases and Healthy Volunteers.
Lung cancer remains the leading cause of cancer-related death in the UK, with over 35,000 deaths annually and most cases diagnosed at a late stage.
- Conditions
- Lung Cancer (Diagnosis), Lung Cancer (Suspected or Confirmed), Healthy, Pneumonia
- Trial name
- VICTORY 2 (NCT07426718)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Cystic Fibrosis
Non-Invasive Biomarkers in Cystic Fibrosis
Background Chronic airway inflammation is present in cystic fibrosis. Non-invasive inflammometry may be useful in disease management.
- Trial name
- NCT00413140
- Where
- 4 sites in Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Asthma, COPD Exacerbation
Study to Explore the Relationship Between the Level of Exhaled Breath Condensate Hydrogen Peroxide (EBC H2O2) as Measured Using a New Device Against Existing Measures of Lung Disease
A cross-sectional, observational study of EBC H2O2 levels, as measured by a novel device, 'Inflammacheck™', and other markers of disease severity and symptom control in patients with Asthma and COPD and volunteers with no history…
- Trial name
- EXHALE 1A (NCT04061291)
- Where
- United Kingdom
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Pulse Spectrum Analysis, Pulmonary Function
Pulse Spectrum Analysis in Adult Asthmatics: Correlation With Lung Function, Asthma Control Exhaled Nitric Oxide and Metabolites in Exhaled Breath Condensate
Our hypothesis is that radial arterial pulse may reflect the severity and airway function in asthmatics. The aims of this study are to investigate the pulse spectrim of the radial artery in adult asthmatics, and evaluate its…
- Conditions
- Pulse Spectrum Analysis, Pulmonary Function, FeNO, Metabolites
- Trial name
- NCT01719393
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Asthma, Cystic Fibrosis
Standardisation of Measurements in Exhaled Breath and Exhaled Breath Condensate.
Background: in various pediatric pulmonary diseases such as asthma, cystic fibrosis or bronchopulmonary dysplasia an increased inflammation is present.
- Conditions
- Asthma, Cystic Fibrosis, Chronic Lung Disease, Pneumonia
- Trial name
- NCT00983671
- Where
- Netherlands
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
COPD Exacerbation
A Cross Sectional, Diagnostic Accuracy Study to Validate the Use of a New Device(Inflammacheck™) in Diagnosing COPD
A cross-sectional, diagnostic accuracy study to evaluate the use of the 'Inflammacheck™' device in the diagnosis of COPD. Participants will be asked to provide an exhaled breath sample for measurement of their EBC H2O2 using…
- Trial name
- EXHALE 1V (NCT04024657)
- Where
- United Kingdom
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Chronic Obstructive Pulmonary Disease
Systemic Endothelial Abnormalities in COPD
The purpose of this project is to validate the peripheral arterial pressure waveform measurements technique of RAAP (radial artery applanation tonometry), in patients with moderate and severe COPD (Chronic Obstructive Pulmonary…
- Trial name
- NCT00555529
- Testing
- radial artery applanation tonometry (RAAP)
- Where
- 2 sites in United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
Tetraplegia, Asthma
Exhaled Breath Condensate Biomarkers of Inflammation in Individuals With Chronic Cervical Spinal Cord Injury
The purpose of this study is to obtain markers of airway inflammation from the exhaled breath condensate (the moisture in exhaled air) for comparison to blood based markers.
- Trial name
- NCT02235714
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Smoking
Young Smokers Have Impaired Airway Defense
Background: Smoking is a key factor for development and progression of chronic obstructive pulmonary disease (COPD). Although persons with COPD often have concomitant nasal disease, there are few studies that report physiological…
- Trial name
- NCT01877291
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo