Clinical trials: Exercise Tolerance
Heart Failure With Preserved Ejection Fraction, Inflammation
Novel Approaches for Improving Vascular Function in Veterans With HFpEF
This project will evaluate the impact of L-Citrulline, tetrahydrobiopterin (BH4), and atorvastatin administration on physical capacity and vascular function in Veterans with heart failure with preserved ejection fraction (HFpEF).
- Trial name
- NCT06312748
- Testing
- L-Citrulline, BH4, Atorvastatin
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- VA Office of Research and Development
Liver Fat, Type 2 Diabetes
EXIT: Prospective Study of the Response to Exercise
Background : Regular exercise is a cornerstone in the prevention and the management of comorbidities. Unfortunately, the metabolic benefit of exercise training is not universal and varies among individuals.
- Trial name
- EXIT (NCT02204670)
- Testing
- Acute release of irisin after a single exercise session.
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Multiple Sclerosis
Ischemic Preconditioning, Exercise Tolerance and Multiple Sclerosis
Regular physical activity improves aspects such as physical fitness, fatigue, quality of life, gait and also reduces the rate of progression of disability in individuals with Multiple Sclerosis.
- Trial name
- NCT03153553
- Testing
- Ischemic Preconditioning
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Resistance Training for the Improvement of Glycemic Control in Prediabetes
The purpose of this research is to study the effects of resistance exercise training with different degrees of effort on your glucose responses (what we call glycemic control) and psychological responses.
- Trial name
- NCT06697756
- Testing
- High-effort resistance exercise training, Low-effort resistance exercise training
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of New Mexico
Impaired Glucose Tolerance
Effects of Physical Activity on the Brain in Impaired Glucose Tolerance (IGT)
The researchers will investigate whether exercise could provide positive effects on general brain functions in elderly people with impaired glucose tolerance.
- Trial name
- NCT01219231
- Testing
- Exercise
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- Charite University, Berlin, Germany
Impaired Glucose Tolerance, Diabetes
The Effects of Exercise on Adipokine in Impaired Fasting Glucose or Impaired Glucose Tolerance Patients
Many adipokines are thought that related with metabolic disturbance such as glucose intolerance, dyslipidemia, and insulin resistance.
- Trial name
- NCT00472342
- Testing
- exercise prescription
- Where
- South Korea
- Volunteers
- 182 people
- Sponsor
- Yonsei University
Incremental Shuttle Walk Test
Reliability of the Incremental Shuttle Walk Test in University Students
The aim of this study is to evaluate the inter-rater and intra-rater reliability of the incremental shuttle walk test in university students.
- Trial name
- NCT06638281
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Siirt University
Exercise, Heat Strain
Effect of Exercise and Heat Stress on Acute Cardiometabolic Adaptations in Healthy Young Adults
Life in space is completely void of physical and environmental stress. It is well known that living things need regular physical stress (e.g. exercise) to remain strong, functional and healthy.
- Conditions
- Exercise, Heat Strain, Control Condition
- Trial name
- NCT06872762
- Testing
- Exercise, Heat strain
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Venous Thromboembolism (VTE), Exercise Therapy
Early Exercise-Based Rehabilitation in Patients Hospitalized for Acute Pulmonary Embolism
Up to half of patients with pulmonary embolism (PE) suffer from impaired quality of life, reduced physical capacity, and symptoms like shortness of breath even three months after diagnosis, despite standard treatment with…
- Conditions
- Venous Thromboembolism (VTE), Exercise Therapy, Quality of Life (QOL), Anxiety Depression
- Trial name
- RehabPE (NCT07143539)
- Testing
- Exercise-based rehabilitation program
- Where
- 6 sites in Switzerland
- Volunteers
- 160 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Covid19, Fatigue Syndrome, Chronic
Use of 1-MNA to Improve Exercise Tolerance and Fatigue in Patients After COVID-19
Coronavirus disease 2019 (COVID-19) is a serious respiratory disease that results from infection with a newly discovered coronavirus (SARS-COV-2).
- Trial name
- NCT04961476
- Testing
- 1-MNA
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Michal Chudzik
Physical Activity, Breast Cancer
Study of Program Interest "Bouge" to Improve the Daily Physical Activity in Processings Treatment of Non-metastatic Breast Cancer
Evaluate the "Bouge" digital program (smartphone application) to increase the daily physical activity of breast cancer patients
- Conditions
- Physical Activity, Breast Cancer, Mobile Health Apps
- Trial name
- BOUGE CANCER (NCT03674515)
- Testing
- Smartphone equipped with application "bouge" = Coach group
- Where
- 2 sites in France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
COPD
Optimization of Pulmonary Rehabilitation Programmes: the OPTION Study
Chronic obstructive pulmonary disease (COPD) has a profound impact on the lives of individuals who suffer from it. Participants with COPD are often caught in a downward spiral that goes from chronic airflow limitation to…
- Trial name
- OPTION (NCT01933308)
- Testing
- Continuous high intensity training-CT80, Training at ventilatory threshold-CTVT, Interval training-IT
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Véronique Pépin
Body Temperature Changes, Heat Stress
Exercise Intensity and Heat Responses in Children and Youth
Little is known about how children and youth regulate body temperature during exercise in the heat compared with young adults, including whether differences in whole-body heat exchange contribute to their responses.
- Conditions
- Body Temperature Changes, Heat Stress, Child Development, Heat
- Trial name
- NCT07781592
- Testing
- Low-Intensity Exercise in the Heat, Moderate-Intensity Exercise in the Heat, Vigorous-Intensity Exercise in the Heat
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Heart Failure
CCM Italian Registry
The Cardiac Contractility Modulation (CCM) system is a cardiac implantable device indicated for the treatment of patients with symptomatic heart failure with left ventricular systolic dysfunction despite optimal medical and…
- Trial name
- NCT04327323
- Testing
- CCM device implantation
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- S. Andrea Hospital
Stroke
Step Test and Six Minute Walk Test in Stroke
The purpose of this study is to investigate the viability of using the Step Test (ST) in stroke patients, and to compare the functional performance of the physiologic variables in stroke patients during ST and Six Minute Walk…
- Trial name
- NCT01436630
- Testing
- Step Test and Six Minute Walk.
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- Faculdades Metropolitanas Unidas
Heart Failure With Normal Ejection Fraction
High-intensity Interval Training in Heart Failure Patients With Preserved Ejection Fraction
This study investigates the effects of a 12-week high-intensity interval training (HIT) on exercise tolerance, functional status and quality of life in patients with chronic heart failure with preserved ejection fraction (HFpEF)…
- Trial name
- HIT-HF (NCT03184311)
- Testing
- High-intensity interval training (HIT), Moderate-intensity contiuous training (MCT)
- Where
- Switzerland
- Volunteers
- 86 people
- Sponsor
- University of Basel
COPD
Continuous Chest Wall Vibration in COPD Rehabilitation
Dyspnea, the sensation of breathing discomfort or shortness of breath, is one of the main symptoms for patients affected by Chronic Obstructive Pulmonary Disease (COPD), particularly during exercise.
- Trial name
- NCT03644888
- Testing
- Cycle ergometer training, Airway clearance program, Vibration therapy
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Coronary Heart Disease
Effects of Yangxinshi Pills on the Exercise Tolerance of the Patients With Coronary Heart Disease
Compared with conventional treatment of the coronary heart disease,the aim of the research is to find out if the addition of Yangxinshi pills on the basis of conventional treatment can improve exercise tolerance of patients with…
- Trial name
- NCT03478332
- Testing
- Yangxinshi pill, conventional coronary heart disease medicine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Affiliated Hospital of Changchun University of Chinese Medicine
Diastolic Heart Failure
A Study of the Effectiveness of Sitaxsentan Sodium in Patients With Diastolic Heart Failure
The aim of this study was to determine whether long-term (≥ 6 months at the target dose) blockade of ETA receptors using sitaxsentan showed functional benefit in subjects with chronic Heart Failure and an Left Ventricular…
- Trial name
- NCT00303498
- Testing
- Sitexsentin sodium
- Where
- 52 sites in United States, Canada
- Volunteers
- 200 people
- Sponsor
- Pfizer
Pulmonary Disease, Chronic Obstructive
Tiotropium (Spiriva) Rehabilitation Study
The study was designed to determine whether tiotropium inhalation capsules, compared to placebo, enhances the improvement in exercise tolerance seen in patients with chronic obstructive pulmonary disease (COPD) who participate in…
- Trial name
- NCT00274521
- Testing
- Tiotropium
- Where
- 19 sites in United States
- Volunteers
- 108 people
- Sponsor
- Boehringer Ingelheim