Clinical trials: Exercise Response, open to volunteers
Parkinson Disease (PD)
Passive Versus Active Music Therapy Parkinson's Disease
The purpose of this pilot study is to identify the effects of active versus passive music therapy on functional ability and psychophysiological responses to goal-directed exercise in people with Parkinson's disease.
- Trial name
- NCT07661524
- Testing
- Passive music therapy, Active music therapy
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- University of Alabama at Birmingham
Prehypertension (Elevated Blood Pressure) or Hypertension, Healthy
Difference in Acute Responses of Vascular Function to Moderate-intensity and High-intensity Interval Training in Healthy and Prehypertensive Individuals
In this study, the investigators will evaluate acute changes in vascular function measures after moderate-intensity continuous and high-intensity interval exercise in healthy and prehypertensive individuals.
- Trial name
- ACT-ON-ACUTE (NCT07048509)
- Testing
- Control-no treatment, Exercise
- Where
- Slovenia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Breast Cancer Lymphedema, Survivorship
Lymphatic Response to Resistance Exercise in Breast Cancer Survivors
The objective of this study is 1) to study the acute and chronic effect of resistance therapeutic physical exercise (RTPE) in the prevention of breast cancer-related lymphedema (BCRL) in breast cancer survivors at risk using…
- Conditions
- Breast Cancer Lymphedema, Survivorship, Lymphedema of Upper Limb
- Trial name
- LinfoGYM (NCT06113627)
- Testing
- Resistance Therapeutic Exercise
- Where
- Spain
- Volunteers
- 170 people
- Sponsor
- University of Malaga
Exercise, BDNF
Sex Differences in BDNF Study
A single bout of exercise can improve cognitive abilities like memory and attention. These functions help us navigate through everyday life. However, we do not fully understand how exercise improves cognitive abilities.
- Conditions
- Exercise, BDNF, Sex Differences
- Trial name
- BDNF-SD (NCT07912307)
- Testing
- VO2peak Test
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McMaster University
Fibromuscular Dysplasia, Spontaneous Coronary Artery Dissection
A Study Of Exercise In Patients With Spontaneous Coronary Artery Dissection And Fibromuscular Dysplasia
The purpose of this study is to assess the cardiopulmonary, hemodynamic, and symptom responses to acute bouts of varying intensity aerobic and resistance exercise in people with Spontaneous Coronary Artery Dissection (SCAD)…
- Trial name
- NCT07526766
- Testing
- Aerobic and resistance exercises
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Mayo Clinic
Non-Small Cell Lung Cancer, Exercise Training
EXERCISE AND THE IMMUNE RESPONSE IN LUNG CANCER
This project is about the effect of a 12-week training therapy intervention in patients suffering from non-small cell and small-cell lung cancer.
- Conditions
- Non-Small Cell Lung Cancer, Exercise Training, Immunotherapy, Small Cell Cancer Of The Lung
- Trial name
- ImmuEX (NCT07267000)
- Testing
- Exercise, Control
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Graz
Exercise Response
Caffeine Mouth Rinse on Salivary Immunoglobulin A, Lactoferrin and A-Amylase Levels
The goal of this clinical trial is to investigate the effects of the mouth rinse form of caffeine (400 mg) on salivary lactoferrin, α-amylase and secretory immunoglobulin-a levels after incremental exercise in young amateur…
- Trial name
- NCT06704711
- Testing
- Caffeine 300 MG, Exercise
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Acute Phase Response
Defining the Temporal Changes in the Acute Phase Response During Graded Exercise: A Prospective Study
The purpose of this study is to detail the precise temporal changes in the APR that occur in response to exercise in order to determine the types of exercise that confer maximal reparative fibrinolysis.
- Trial name
- NCT03398304
- Testing
- Graded Exercise, Marathon participation
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Exercise Performance
U-LABA/ICS Effects on Exercise Performance, Vilanterol
The purpose of the project is to investigate exercise performance in humans following bronchodilation induced by acute inhalation of beta2-agonist vilanterol + fluticasone furoate
- Trial name
- NCT06066606
- Testing
- Vilanterol and Fluticasone Furoate (low dose), Vilanterol and Fluticasone Furoate (high dose)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Crohn's Disease
Vibration Exercise for Crohn's to Observe Response
Background: Crohn's disease (CD) is a long-term inflammatory condition of the digestive system. People with CD often have unpredictable and debilitating symptoms, including abdominal pain, diarrhoea and fatigue.
- Trial name
- VECTOR (NCT06211400)
- Testing
- Whole body vibration exercise
- Where
- United Kingdom
- Volunteers
- 168 people
- Sponsor
- University of Hertfordshire
Exercise Physiology, Nutritional Supplementation
Effects of Pre-Run Nutritional Supplements During a Fixed-Pace 5 km Treadmill Run
This study will examine how three commonly used pre-run nutritional supplements-caffeine, L-citrulline, and an exogenous ketone supplement-affect physiological and perceptual responses during a fixed-pace 5 km treadmill run in…
- Trial name
- NCT07854223
- Testing
- Caffeine, L-Citrulline, Exogenous Ketone (Beta-Hydroxybutyrate)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Restless Legs Syndrome
Blood Changes After Exercise in Restless Legs Syndrome
The goal of this clinical trial is to learn how exercise changes molecules in the blood in people with restless legs syndrome (RLS) to better understand the cause(s) of RLS.
- Trial name
- PEARLS (NCT06481176)
- Testing
- 12-Week RLS Exercise Program
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Overweight (BMI > 25), Obesity
Redox Status and Exercise Training-induced Adaptations
Excess fat accumulation is a key feature of overweight and obesity that is mainly driven by nutrient overload and insufficient physical activity.
- Trial name
- NCT07196852
- Testing
- N Acetyl L Cysteine
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Cancer, Colorectal Cancer
Alberta Cancer Exercise Dose in Colorectal Cancer
The purpose of this pilot randomized, wait-list controlled study is to evaluate the effects of exercise dose in terms of frequency (1 vs. 2 days per week) in individuals on systemic treatment for colorectal cancer.
- Trial name
- ACE-Dose-CRC (NCT07913906)
- Testing
- Group Exercise Classes - Arm 1, Group Exercise Classes - Arm 2
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Calgary
Asthma (Diagnosis)
Respiratory Admittance by Oscillometry in Children
Oscillometry is a pulmonary function testing technique suited for children because it does not require specific respiratory maneuvers like spirometry.
- Trial name
- ArsEIB (NCT07771608)
- Volunteers
- 144 people
- Sponsor
- Central Hospital, Nancy, France
Breast Cancer
Improving Response to Chemotherapy by Adding Physical Exercise in the Neoadjuvant Setting of Breast Cancer Patients
One of the recommended treatments for breast cancer is neoadjuvant chemotherapy (NCT), however, only 20% of the patients subject to this therapy present pathologic complete response (pCR).
- Trial name
- KEYMOVE (NCT05976815)
- Testing
- Combined Aerobic and Resistance Exercise
- Where
- Portugal
- Volunteers
- 86 people
- Sponsor
- University Institute of Maia
Diabete Type 2, Aerobic Exercise
Type 2 Diabetes Mellitus and Downhill Aerobic Exercise Training
The purpose of this study is to compare the effects of an 8-week supervised downhill walking training program, prescribed based on the 6-minute walk test, on functional capacity, peripheral muscle strength, and cardiovascular…
- Conditions
- Diabete Type 2, Aerobic Exercise, Walking
- Trial name
- NCT07693296
- Testing
- Downhill Aerobic Walking Training, Level Aerobic Walking Training, Home exercise session
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Acibadem University
Major Depressive Disorder, Inflammatory Response
Cerebral and Anti-inflammatory Response Through Exercise - Mechanisms In Depressive Disorders
The goal of this clinical trial is to study how physical exercise works when applied to patients diagnosed with Major Depressive Disorder (MDD).
- Trial name
- CARE-MIND (NCT06450704)
- Testing
- Physical Exercise, Antidepressant medication (ADM)
- Where
- 5 sites in Spain
- Volunteers
- 124 people
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Healthy Adult Females
Effect of Pre-exercise Inhalation of Molecular Hydrogen on Metabolic Response During Graded Exercise in Healthy Women
The goal of this clinical trial is to evaluate if molecular hydrogen can reduce the metabolic response during graded exercise in healthy women aged 18-30 years.
- Trial name
- NCT07644000
- Testing
- Molecular hydrogen
- Where
- Czechia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Palacky University
Head and Neck Squamous Cell Carcinoma HNSCC
Exercise Therapy in Head and Neck Squamous Cell Carcinoma (HNSCC)
The goals of this clinical trial are to learn 1. Determine the feasibility of a home-based exercise analog therapy using Transcutaneous Electrical Nerve Stimulation (TENS), 2.
- Trial name
- NCT06839014
- Testing
- Exercise
- Volunteers
- 40 people
- Sponsor
- Our Lady of the Lake Hospital