Clinical trials: Exercise Induced Muscle Damage
Tendon Injuries
GSK1278863 Effects on Eccentric Exercise-Induced Muscle Damage
As per non-clinical studies, prolyl hydroxylase inhibitor GSK1278863 can protect muscle from unaccustomed exercise induced muscle damage and enhance functional muscle repair.
- Trial name
- NCT02231190
- Testing
- GSK1278863
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Exercise-induced Muscle Soreness
Effects of Traumeel®S Tablets on Exercise Induced Muscle Damage and Muscle Soreness
To investigate and compare the effects of Traumeel®S tablets versus placebo on exercise induced muscle damage and muscle soreness for 72 hours after strenuous eccentric exercise test on downhill treadmill.
- Trial name
- NCT01912469
- Testing
- Traumeel
- Where
- Germany
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. med. Frank Christoph Mooren
Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation
NAC Supplementation and Soccer Specific Performance
In this investigation the investigators utilized NAC supplementation to boost GSH availability during an one-week-microcycle consisting of three soccer games, in order to test the hypotheses that: i) antioxidant supplementation…
- Conditions
- Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation, Skeletal Muscle Performance, Antioxidant Status
- Trial name
- NCT04523675
- Testing
- N-acetylcysteine
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Focus on Omega 3 Index on Recovery
Long-Term Omega-3 and Omega-3 Index >8%: Effects on Physiological Recovery
The Omega-3 Index measures how much of the Omega-3 fats EPA and DHA are built into red blood cell membranes. These fats are essential for health, but the body cannot make enough of them, so they must come from foods like oily…
- Trial name
- IMPROVE-8 (NCT07439601)
- Testing
- Oil Supplementation
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Exercise-induced Muscle Damage
Exercise-induced Muscle Damage is Reduced in Resistance Trained Athletes by Branch Chain Amino Acids
It is well documented that exercise-induced muscle damage (EIMD) decreases muscle function and causes severe soreness and discomfort.
- Trial name
- NCT01529281
- Testing
- Branch Chain Amino Acid (BCAA)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Sarcopenia
Protein Intake and Exercise-induced Muscle Damage
The goal of this clinical trial is to test the effect of different protein-enhancement strategies versus carbohydrate control on exercise-induced muscle damage in physically active older adults.
- Trial name
- PROMO (NCT06235476)
- Testing
- whey protein supplement, mixed plant-based protein supplement, e-health application
- Where
- Netherlands
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Muscular Injury
Pea Protein Supplementation and Muscle Damage
The purpose of this study is to determine if supplementation with NUTRALYS pea protein isolate compared to whey protein and apple juice (carbohydrate, non-protein control) before, during, and after a 90-minute bout of eccentric…
- Trial name
- NCT03448328
- Testing
- NUTRALYS pea protein supplement, Whey Protein, Apple juice
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Muscle Injury, Muscle Soreness
Effects of Wobenzym® Plus in Healthy, Sportive People After Eccentric Exercise
The aim of the current study is to investigate the therapeutic effect and especially the mode of action of Wobenzym® plus, an anti-inflammatory drug containing proteolytic enzymes, on exercise induced muscle damage (eiMD) and…
- Conditions
- Muscle Injury, Muscle Soreness, Exercise Induced Muscle Damage
- Trial name
- 2012-005003-40 (NCT01845558)
- Testing
- Wobenzym® plus
- Where
- Germany
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Mucos Pharma GmbH & Co. KG
Healthy, Athletes
Evaluation of the Ergogenic Properties of Hesperetin on Exercise-induced Fatigue
Twenty young, healthy, physically active men and women (12~30 years) did a pre-post trial randomized into placebo or HST trials (500 mg/d for two weeks).
- Trial name
- NCT07104734
- Testing
- Hesperetin (Hesperetin trial)
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Exercise-Induced Fatigue, Muscle Fatigue
Effect of Lactobacillus Plantarum GKK1 Supplementation on Anti-fatigue Health Effects
Title: Effect of Lactobacillus plantarum GKK1 Supplementation on Anti-Fatigue Health Effects: A Randomized, Double-Blind, Placebo-Controlled Trial This study aims to investigate the effects of Lactobacillus plantarum GKK1…
- Conditions
- Exercise-Induced Fatigue, Muscle Fatigue, Sports Performance, Fatigue Recovery
- Trial name
- GKK1-Fatigue (NCT06893549)
- Testing
- Lactobacillus plantarum GKK1 Probiotic
- Where
- Taiwan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Exercise Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS)
Effects of a 5-Week Probiotic Supplementation Intervention on Markers of Delayed Onset Muscle Soreness
The purpose of this study is to evaluate how probiotic supplementation (PS) influences post-exercise recovery in healthy, physically active young adults.
- Trial name
- NCT07219498
- Testing
- Lactobacillus casei
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Muscle Damage
The Effect of New Zealand Blackcurrant (NZBC) Supplementation on Recovery Following Strenuous Exercise
The study aims to examine the effect of a New Zealand blackcurrant (NZBC) supplement on markers of muscle damage and recovery following strenuous resistance exercise.
- Trial name
- CurraNZ_MD (NCT05010057)
- Testing
- New Zealand blackcurrants (NZBC)
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Muscle Damage
Made to Measure Compression Garments for Recovery in Rugby Players
Aims To compare the compression pressures exerted by made-to-measure compression garments (CG) with those from standard sized garments To assess the efficacy of custom fitted, high pressure CG for facilitating the recovery of…
- Trial name
- NCT03707470
- Testing
- Custom fitted compression garments (CF), Standard-sized compression garments (SSG)
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Muscle Recovery
Investigating the Efficacy of Low or High Dose Tart Cherry on Recovery From Exercise Induced Muscle Damage and Establishing Its Molecular Mechanisms of Action
To determine the dose-response effects of 10-day tart cherry product consumption (0, 30 ml, and 60 ml) on knee extensor isometric strength 24-h and 48-h after muscle damaging exercise and to elucidate the mechanisms of action for…
- Trial name
- NCT04725149
- Testing
- 500 ml base solution, 500 ml containing 30 ml tart cherry concentrate diluted with water and base solution, 500 ml containing 60 ml tart cherry concentrate diluted with water only
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Exercise Induced Muscle Damage, Physical Activity
Walk It Off! the Influence of Physical Activity Level on the Recovery from Damaging Resistance Exercise
After completing novel activity or exercise we may experience exercise-induced muscle damage (EIMD), resulting in a period of reduced muscle function and delayed onset muscle soreness (DOMS).
- Conditions
- Exercise Induced Muscle Damage, Physical Activity, Inflammation, Exercise Recovery
- Trial name
- WIO (NCT06810271)
- Testing
- Eccentric resistance exercise
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Myalgia [C05.651.542]
Cryotherapy and Laser Therapy on Muscle Damage
This study propose investigate the effect of cryotherapy and laser therapy in response to strenuous exercise-induced muscle damage on the biceps brachii muscle (muscle of the arms).
- Trial name
- CLMD (NCT02327988)
- Testing
- Cryotherapy, Laser therapy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Bandages, Muscle Soreness
Kinesio Taping in Muscle Damage Response Induced by Eccentric Exercise
Sixty volunteers with a mean age of 21,8 ± 2,6 years participated in this study, randomly distributed into one of the following groups: control, Kinesio taping group with tension in the anterior arm region and Kinesio taping…
- Trial name
- NCT02945098
- Testing
- Kinesio Taping
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Exercise-induced Myocardial Damage, Right Ventricular Diastolic Dysfunction
Effects of Exogenous Ketones on Acute Changes and Recovery of the Heart Muscle After Intense Exercise.
It is well known that scar tissue on the heart muscle can cause (life-threatening) arrhythmias. However, the exact cause of this scar tissue is not entirely clear.
- Trial name
- NCT06715748
- Testing
- Ketone Monoester (KE)
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Oxidative Stress, Healthy
A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance
This is a prospective, randomized, placebo controlled, double-blind study to assess the effects of a postbiotic blend on exercise induced oxidative stress markers and exercise performance in healthy adult.
- Conditions
- Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness
- Trial name
- PBE (NCT06795425)
- Testing
- Postbiotic Active Lifestyle Blend
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Muscle Damage, Muscle Soreness
The Effects of Whey Protein Supplements on Markers of Exercise-induced Muscle Damage in Resistance-trained Individuals
Intense exercise can bring about various side effects to one's body. Less range of motion, increased pain sensitivity, increased muscle swelling, and decreased muscle strength can occur immediately after exercise.
- Trial name
- WheyProtein (NCT05100459)
- Testing
- Pasture-raised whey protein, Conventional whey protein
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Indiana University