Clinical trials: Exercise Capacity
Heart Failure
Inspiratory Muscle Training for People With Heart Failure
Heart failure is frequently associated with inspiratory muscle weakness, which contributes to dyspnea, reduced exercise capacity, impaired quality of life, and adverse cardiovascular outcomes.
- Trial name
- NCT07672041
- Testing
- Inspiratory muscle training with Tapered Resistive Load, Inspiratory muscle training with threshold load, Concurrent Exercise Training
- Where
- Chile
- Volunteers
- 108 people
- Sponsor
- Universidad Nacional Andres Bello
Chronic Obstructive Pulmonary Disease
Effects of Strength Training in Combination With Endurance Training on Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Background. Exercise intolerance is one of the most devastating consequences of chronic obstructive pulmonary disease (COPD). Abnormalities in peripheral muscle function such as weakness and reduction in oxidative enzyme…
- Trial name
- NCT01091623
- Testing
- training
- Where
- Austria
- Volunteers
- 36 people
- Sponsor
- Medical University of Vienna
Older Adults (60 - 85 Years Old)
Gymnastics and Multicomponent Training Intervention in Community-dwelling Older Adults
Introduction: Extension projects focused on physical activity can offer health practices and promote quality of life for participants of different ages.
- Trial name
- NCT07766954
- Testing
- Multicomponent training intervention Multicomponent training intervention - Protocol includes mobility, resistance exercises for the lower and upper limbs and major muscle groups, and aerobic exercise
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Diastolic Heart Failure
A Randomized Trial of Udenafil Therapy in Patients With Heart Failure With Preserved Ejection Fraction [ULTIMATE-HFpEF]
The investigators hypothesized that udenafil, a newly developed phosphodiesterase type 5 inhibitor, would improve symptom, exercise capacity and hemodynamic status in patients with heart failure with preserved ejection fraction…
- Trial name
- NCT01599117
- Testing
- Udenafil (Zydena)
- Where
- 2 sites in South Korea
- Volunteers
- 52 people
- Sponsor
- Seoul National University Hospital
Heart Failure, Systolic Heart Failure
Effects of Postural Balance Exercises in Patients With Heart Failure
In this study, the effects of core stabilization and computerized wobble board exercise training programs on postural balance and functional exercise capacity in patients over 60 years of age with heart failure will be…
- Conditions
- Heart Failure, Systolic Heart Failure, Diastolic Heart Failure
- Trial name
- NCT04937790
- Testing
- Core stabilization group(CSG), Wobble board group (WBG)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Giresun University
Athlete
Effects of Coenzyme Q10 Supplementation on Oxidative Stress, Antioxidant Capacity, Inflammatory Responses, Fatigue Elimination, and Exercise Performance in Athletes
The aims of the study are 1) to compare the differences in plasma coenzyme Q10, oxidative stress, antioxidant capacity, muscle impairment, fatigue recovery, and inflammation and exercise performances in athletes (i.e., soccer…
- Trial name
- NCT03321110
- Testing
- Coenzyme Q10
- Where
- Taiwan
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Cardiovascular Disease, Exercise
Intermittent Hypoxia Therapy in Cardiac Rehabilitation
This is a randomized control pilot study to assess the effect of intermittent hypoxia therapy on functional capacity vs conventional care in old patients with functional impairment admitted to a Phase 2 in-hospital cardiac…
- Conditions
- Cardiovascular Disease, Exercise, Hypoxia
- Trial name
- NCT04034082
- Testing
- Intermittent hypoxia therapy, Conventional phase 2 cardiac rehabilitation programme
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Type 2 Diabetes
Comparison of Physical Function and Quality of Life in Insulin and Non-Insulin Users With Type 2 Diabetes
This clinical trial aims to compare the muscle strength, functional exercise capacity, physical activity levels, and quality of life between insulin-using and non-insulin-using patients with Type 2 diabetes.
- Trial name
- NCT06935396
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Copd, Tuberculosis
Pulmonary Tuberculosis Sequelae in Patients With COPD
It is known that there is a complex relationship between tuberculosis and COPD. Post-tuberculosis airway disease or COPD associated with tuberculosis occurs in a significant portion of tuberculosis patients.
- Conditions
- Copd, Tuberculosis, Quality of Life
- Trial name
- NCT04721080
- Testing
- Functional Outcome Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Izmir Katip Celebi University
Adult Congenital Heart Disease, Heart Failure
Efficacy Of Sodium Glucose Transporter Inhibitor (SGLT2I) In Adult Patients With Congenital Heart Disease
The goal of the study is to investigate the feasibility and benefit of novel guideline-directed heart failure therapy drug Empagliflozin (Jardiance) for adult patients with congenital heart disease (ACHD).
- Trial name
- EmpaCHD (NCT06260059)
- Testing
- Empagliflozin 10 MG
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Anita Saraf
COVID-19
Effects of a N95 Respirator vs Cloth Mask on Exercise Capacity During Treadmill Exercise.
This study intends to find out how a cloth mask may impact exercise capacity, to provide guidance for exercisers to adjust their expectations and training accordingly.
- Trial name
- NCT04415879
- Testing
- N-95 Respirator, Cloth Face Mask
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Obesity Hypoventilation Syndrome, Obesity
The Effect of Obesity Hypoventilation Syndrome on Exercise Capacity, Peripheral Muscle Strength, and Quality of Life in Obese Individuals
Obesity Hypoventilation Syndrome(OHS) is a disease characterized by daytime hypercapnia and sleep-disordered breathing without other causes of hypoventilation in individuals with a body mass index above 30 kg/m2.
- Conditions
- Obesity Hypoventilation Syndrome, Obesity, Hypoventilation, Respiration Disorders
- Trial name
- NCT06142513
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istanbul University
Coronary Artery Disease
Effect of Exercise Training on the Function of HDL-Cholesterol, Endothelial Function and Endothelial Progenitor Cells in Patients With Coronary Artery Disease (HERCET-Study)
Patients with coronary artery disease are characterized by an increased cardiovascular risk and they often have low blood high density lipoprotein (HDL)-cholesterol levels or HDL-cholesterol with modified vasculoprotective…
- Trial name
- HERCET (NCT00457379)
- Testing
- physical exercise
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Age-Related Balance Impairment, Healthy Older Adults
Effects of Dynamic Neuromuscular Stabilization Exercises Versus Balance Exercises in Older Adults
The aim of this study is to compare the effects of Dynamic Neuromuscular Stabilization (DNS) based exercises and balance exercises on functional capacity, balance, muscle strength, and quality of life in older adults.
- Trial name
- NCT07495280
- Testing
- Dynamic Neuromuscular Stabilization Exercises, Balance Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
End-Stage Renal Disease Requiring Haemodialysis
Effects of Supervised Exercise Training on Erythrocyte Deformability in Hemodialysis Patients
This study evaluated red blood cell function and aerobic capacity in adults receiving maintenance hemodialysis and in healthy reference participants.
- Trial name
- NCT07836881
- Testing
- Supervised Exercise Training
- Where
- Taiwan
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Asia University
Heart Failure
Low Intensity Physical Activity in Congestive Heart Failure Patients Among Different BMI
This study examined the effects of low-intensity physical activity on functional capacity, quality of life, and psychological well-being in congestive heart failure patients with varying BMI.
- Trial name
- NCT07062900
- Testing
- Low-Intensity Physical Activity, usual care
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Copd
High Protein and Energy Diet for Better Coughing in COPD Patients
Chronic Obstructive Lung Disease (COPD) is one of the leading death causes worldwide. COPD is a disease that is characterized by chronic inflammation which leads to irreversible damage of airways and lung tissue.
- Trial name
- NCT03923764
- Testing
- High protein and energy diet, Habitual Diet
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- University of Copenhagen
Functional Disability, Dynapenia
Multicomponent Training on Functional and Cognitive Performance of Hospitalized Older People
The goal of this clinical trial is to determine whether a multicomponent physical exercise program improves functional and cognitive capacity in hospitalized older adults compared to the usual hospital care.
- Conditions
- Functional Disability, Dynapenia, Cognitive Decline
- Trial name
- NCT06682598
- Testing
- Multicomponent physical exercise training
- Where
- Brazil
- Volunteers
- 47 people
- Sponsor
- Federal University of Rio Grande do Sul
Pulmonary Hypertension
Pulmonary Hypertension and Measurement of Exercise Capacity Remotely
Background Hospital-based walking exercise tests are routinely used in patients with pulmonary hypertension to assess functional ability and disease progression over time.
- Trial name
- PERSPIRE (NCT04903704)
- Testing
- 1 Minute Sit to Stand Test
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Pulmonary Hypertension
Impact of NMES on Spirometry Values, Functional Capacity and Quality of Life in Patients With Pulmonary Hypertension
Pulmonary hypertension (PH) features symptoms related to a decreased cardiac autonomic response, pulmonary function and exercise capacity.
- Trial name
- NCT02712294
- Testing
- Neuromuscular Electrical Stimulation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo