Clinical trials: Eustachian Tube Dysfunction
Ear Barotrauma, Middle Ear Disease
Effect of Rate (Slope) of Compression on the Incidence of Symptomatic ETD and MEB: a Phase III Prospective Study.
Eustachian tube dysfunction (ETD) and middle ear barotrauma (MEB) are common reported complications during hyperbaric oxygen treatment.
- Conditions
- Ear Barotrauma, Middle Ear Disease, Ear Diseases, Pressure Injury
- Trial name
- NCT04804098
- Testing
- Compression Profile/Schedule: 15 minute Non-Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw), Compression Profile/Schedule: 15 minute Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw)
- Where
- United States
- Volunteers
- 1,553 people
- Sponsor
- Northwell Health
Patulous Eustachian Tube Dysfunction, Eustachian Tube Dysfunction
Nasal Dilator Therapy for Patulous Eustachian Tube Dysfunction
The Eustachian tube connects the middle ear to the back of the nose and throat, providing ventilation of the middle ear. People with a patulous Eustachian tube perceive the tube stays open continuously.
- Trial name
- NCT07796139
- Testing
- Internal nasal dilator
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Methodist Hospital Research Institute
Dysfunction of Eustachian Tube
AERA Pediatrics Registry
Prospective, multi-center, observational, real-world evidence data collection registry to confirm the continued clinical performance of the AERA® device in pediatric patients
- Trial name
- NCT07071298
- Where
- 9 sites in United States
- Volunteers
- 300 people
- Sponsor
- Integra LifeSciences Corporation
Otitis Media
Effect of Simethicone on Eustachian Tube Dysfunction
This study is designed to measure the effects of a chewable Simethicone tablet taken by mouth on middle-ear pressure in adults with a common cold and evidence of abnormal middle-ear pressure.
- Trial name
- NCT01312038
- Testing
- Simethicone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Pittsburgh
Eustachian Tube Dysfunction, Barotitis
Efficacy of Balloon Dilation of the Eustachian Tube in Eustachian Tube Dilatory Dysfunction
This study is being conducted to learn more about a procedure, balloon dilation of the eustachian tube, in treating patients with eustachian tube dysfunction.
- Trial name
- NCT05719207
- Testing
- Balloon dilation of eustachian tube
- Where
- 2 sites in Canada
- Volunteers
- 76 people
- Sponsor
- University of Calgary
Eustachian Tube Dysfunction, Facial Pain
SinuSonic for ETD and Facial Pain: Acoustic Vibration + Oscillating Expiratory Pressure
This study was originally designed with three aims: (1) healthy controls to assess nasal nitric oxide, (2) adults with Eustachian Tube Dysfunction (ETD), and (3) adults with facial pain/pressure.
- Trial name
- NCT04404036
- Testing
- SinuSonic Device
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Otic Barotrauma, Pressure Injury
Diagnostic Precision and Accuracy Using the Teed Scoring System Versus the O'Neill Grading System
This validation study investigates the diagnostic precision and accuracy when grading otic barotrauma using two alternative gradings systems including the TEED and the OGS grading systems.
- Conditions
- Otic Barotrauma, Pressure Injury, Ear Injury, Barotitis
- Trial name
- OGS (NCT04726306)
- Testing
- Otic Barotrauma Grading System
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Eustachian Tube Disorder
Long Term Evaluation of Tubal Expansion on Obstructive Dysfunctions of Eustachian Tube
The study aim is to evaluate the tubal score on patients who suffer from obstructive dysfunction of eustachian tube before and after the eustachian tube dilatation.
- Trial name
- NCT02123277
- Testing
- Balloon catheter for the Eustachian tube
- Where
- France
- Volunteers
- 31 people
- Sponsor
- University Hospital, Montpellier
Eustachian Tube Dysfunction, Middle Ear Barotrauma
Effect of Total Compression Time and Rate (Slope) on Incidence of Symptomatic ETD and MEB: A Phase II Prospective Study.
Eustachian tube dysfunction (ETD) and middle ear barotrauma (MEB) are common reported complications during hyperbaric oxygen treatment.
- Conditions
- Eustachian Tube Dysfunction, Middle Ear Barotrauma, Middle Ear Disease, Middle Ear; Injury
- Trial name
- NCT04776967
- Testing
- Hyperbaric Compression Profile
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwell Health
Eustachian Tube Dysfunction, Sudden Hearing Loss
What is the Tympanic Membrane Healing Time After Insertion of a Gelfoam PE Tube?
Pilot study done to evaluate the breakdown and and potential utility of a bioabsorbable ventilation ear tube made with gelatin.
- Conditions
- Eustachian Tube Dysfunction, Sudden Hearing Loss, Meniere Disease
- Trial name
- NCT04902963
- Testing
- PE tube
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Skovlund Medical Products, LLC
Otitis Media With Effusion (OME), Eustachian Tube Dysfunction
EarFlo: A Non-Invasive Treatment for Otitis Media With Effusion & Eustachian Tube Dysfunction in Adults
This study evaluates the use of the EarFlo device in adults with clinically confirmed Eustachian tube dysfunction and/or otitis media with effusion.
- Conditions
- Otitis Media With Effusion (OME), Eustachian Tube Dysfunction, Otitis Media With Effusion
- Trial name
- NCT07777302
- Testing
- EarFlo Device
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Philip Perez
Eustachian Tube Dysfunction
Long-term Assessment of Balloon Eustachian Tuboplasty for Obstructive Eustachian Tube Disease
To date, more than 130 000 Balloon Eustachian Tuboplasty (BET) procedures have been performed worldwide. This procedure is proposed in case of Obstructive Eustachian Tube Dysfunction (OETD) with or without chronic otitis media.
- Trial name
- LASt-BET (NCT05998356)
- Testing
- Balloon Eustachian Tuboplasty (BET) under general anesthesia., Insertion of catheter for probing and flushing the Eustachian tube under general anesthesia
- Volunteers
- 96 people
- Sponsor
- University Hospital, Montpellier
Eustachian Tube Dysfunction
Effect of Novel Exhalational Delivery System With Fluticasone (EDS-FLU) on Eustachian Tube Dysfunction (ETD)
Intranasal nasal steroid sprays are the mainstay of treatment for chronic Eustachian tube dysfunction despite having little supportive evidence in the literature.
- Trial name
- NCT05275686
- Testing
- Fluticasone Propionate 93 MCG/1 ACTUATION Nasal Spray
- Where
- 4 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Tonsillar Hypertrophy, Eustachian Tube Dysfunction
Evaluation of Eustachian Tube Function With 226 and 1000 Hz Probes in Children Undergoing Tonsillectomy ± Adenoidectomy
In children undergoing tonsillectomy ± adenoidectomy without eustachian dysfunction, the objective is to control tubal functions with tympanometry utilising probes at 226 Hz and 1000 Hz, as well as measuring the ipsilateral and…
- Conditions
- Tonsillar Hypertrophy, Eustachian Tube Dysfunction, Tympanic Membrane Disorder, Eustachian Tube Dysfunction of Both Ears
- Trial name
- NCT06577051
- Testing
- Eustachian tube function test with 226 and 1000 Hz probes
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Sumeyra DOLUOGLU
Eustachian Tube Dysfunction
Balloon Dilation in Selected Subjects With Refractory Eustachian Tube Dysfunction
This study evaluates the usefulness and safety of using a balloon to dilate (make larger) the Eustachian tube in adults who have middle-ear disease due to Eustachian tube dysfunction.
- Trial name
- NCT02114762
- Testing
- Balloon dilation of the Eustachian tube
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Pittsburgh