Clinical trials: Esophagectomy, open to volunteers
Esophageal Neoplasms, Lymph Node Metastases
Distribution of Lymph Node Metastases in Esophageal Carcinoma
Background: Lymph node status is an important prognostic parameter in esophageal carcinoma and an independent predictor of survival.
- Trial name
- TIGER (NCT03222895)
- Where
- 19 sites in United States, Brazil and 12 more
- Volunteers
- 5,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Esophageal Cancer, Surgery-Complications
Comparison of Endoscopy and Esophagram for the Routine Evaluation of Anastomosis After McKeown Esophagectomy
This retrospective cohort study reviewed patients who underwent McKeown esophagectomy. All patients routinely underwent either endoscopy or esophagram for the evaluation of anastomosis on postoperative day 7.
- Trial name
- NCT07043491
- Testing
- Endoscopy
- Where
- China
- Volunteers
- 2 people
- Sponsor
- Sun Yat-sen University
Esophageal Cancer
Modular Robot-Assisted Versus Conventional Minimally Invasive Esophagectomy for Esophageal Cancer
This study evaluates the safety, efficacy, and health economic outcomes of modular robotic-assisted minimally invasive esophagectomy (RAMIE) compared with conventional thoracoscopic minimally invasive esophagectomy (MIE) in…
- Trial name
- mRAMIE2026 (NCT07888140)
- Testing
- Modular Robot-Assisted Esophagectomy, Conventional Minimally Invasive Esophagectomy
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Ruijin Hospital
Esophageal Cancer (EsC), Sarcopenia
Health Informatics and Resistance Exercise for Symptom Management and Quality of Life in Post-Esophagectomy Patients
Participants are invited to take part in a research study. In accordance with the requirements of the health authorities, participants must be informed of the purpose of the study and its potential risks.
- Conditions
- Esophageal Cancer (EsC), Sarcopenia, Quality of Life
- Trial name
- NCT07180134
- Testing
- symptom management health informatics plus Resistance band exercise training, Usual Care Group
- Volunteers
- 90 people
- Sponsor
- Chang Gung Memorial Hospital
Surgical Procedure, Unspecified
RAE Versus MIE in Patients With Esophageal Cancer After Neoadjuvant Therapy
This is a prospectively randomized controlled trial to compare RAMIE and MIE in the treatment for locally advanced ESCC after neoadjuvant therapy.
- Trial name
- NCT06012214
- Testing
- ROBOTIC-ASSISTED ESOPHAGECTOMY
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai Chest Hospital
Oesophageal Cancer
Use of Different Enteral Feeds to Impact on Chyle Leaks in Oesophagectomy
Oesophagectomy (surgery to remove a cancerous portion of the oesophagus or gullet) is the cornerstone of treating oesophageal cancer.
- Trial name
- NCT06965205
- Testing
- MCT feeding, Standard feeds
- Volunteers
- 160 people
- Sponsor
- Royal College of Surgeons, Ireland
Esophageal Cancer
Incidence of 107 Lymph Node Metastasis
the study was to document the incidence o subcarinal lymph node metastasis, and the risk factors of metastasis.
- Trial name
- NCT07165184
- Testing
- no intervention was applied as observation study
- Where
- China
- Volunteers
- 1,100 people
- Sponsor
- Fudan University
Abdomen Cancer, Pancreas Adenocarcinoma (MSI-H)
Implementation of a Pain Management Plan in Major Open Abdominal Surgeries.
Introduction: Major abdominal surgery encompasses a broad range of surgical procedures in heterogeneous patient populations.Management of postoperative pain has received keen attention in recent years with considerable concurrent…
- Conditions
- Abdomen Cancer, Pancreas Adenocarcinoma (MSI-H), Colectomy Left/Right/Total Under Laparotomy, Hepatectomy
- Trial name
- NCT07901582
- Testing
- Epidural administered opioid
- Where
- Greece
- Volunteers
- 58 people
- Sponsor
- National and Kapodistrian University of Athens
Esophagectomy, Dumping Syndrome
Dumping Syndrome After Esophagectomy
Background: Dumping syndrome is a common complication for patients who have undergone surgery for esophageal cancer. It occurs when food moves too quickly from the stomach (or the reconstructed gastric tube) into the small…
- Conditions
- Esophagectomy, Dumping Syndrome, Continous Glucose Measurement
- Trial name
- NCT07605481
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Atrial Fibrillation, Esophageal Carcinoma
Amiodarone for the Prevention of Atrial Fibrillation After Minimally Invasive Esophagectomy in Patients With Esophageal Cancer
This phase II trial studies how well amiodarone works in the prevention of atrial fibrillation (AF) after a minimally invasive esophagectomy (MIE) in patients with esophageal cancer.
- Trial name
- NCT06067438
- Testing
- Amiodarone Hydrochloride, Saline
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- OHSU Knight Cancer Institute
Esophageal Cancer, Recurrent Laryngeal Nerve
The Value of Near-Infrared Fluorescence Imaging in the Protection of the Recurrent Laryngeal Nerve During Minimally Invasive Esophagectomy
The goal of this clinical trial is to learn whether the application of indocyanine green near-infrared imaging system can accurately locate the recurrent laryngeal nerve (RLN) during lymph node dissection in esophageal cancer…
- Conditions
- Esophageal Cancer, Recurrent Laryngeal Nerve, ICG (Indocyanine Green), Lymph Node Dissection
- Trial name
- NCT07406815
- Testing
- ICG (Indocyanine Green)
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Fujian Medical University Union Hospital
Esophageal Cancer, Drainage/Methods
Comparison of Drainage Methods in Minimally Invasive Esophagectomy (DEMURE）
This RCT compares three drainage approaches after minimally invasive esophagectomy (chest tube + thoracic mediastinal drainage tube, thoracic, and abdominal mediastinal drainage tube) to evaluate perioperative outcomes…
- Conditions
- Esophageal Cancer, Drainage/Methods, Postoperative Pain
- Trial name
- NCT07004634
- Testing
- Chest mediastinal tube, Abdominal mediastinal tube, Chest tube + chest mediastinal tube
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Ruijin Hospital
Esophageal Squamous Cell Carcinoma (ESCC), Esophageal Cancer
Indocyanine Green-guided Omental Shield Anastomosis for Cervical Esophagogastric Anastomosis in Minimally Invasive McKeown Esophagectomy
Brief Summary Study title: Indocyanine green (ICG)-guided omental shield anastomosis (ICG-OSA) technique for cervical esophagogastric anastomosis in esophageal cancer surgery Purpose: To evaluate whether a novel surgical…
- Trial name
- NCT07376876
- Testing
- Indocyanine green-guided omental shield anastomosis for cervical esophagogastric anastomosis
- Where
- China
- Volunteers
- 73 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Atelectases, Postoperative Pulmonary
Prevention and Treatment of Early Postoperative Atelectasis Using The MetaNeb System in Patients Underwent Esophagectomy
The goal of this clinical trial is to evaluate whether the MetaNeb® System can effectively prevent and treat early postoperative atelectasis in adult patients admitted to ICU after esophagectomy for esophageal cancer.
- Trial name
- NCT07284056
- Testing
- MetaNeb Therapy, Standard of care
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Shanghai Zhongshan Hospital
Oesophageal Cancer
Post Oesophagectomy Outcomes in a Single Regional Centre in Australia
Literature review/rationale for project Oesophageal cancer is associated with a grim prognosis despite many advances in treatment.
- Trial name
- NCT06662513
- Testing
- No Intervention: Observational Cohort
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- Launceston General Hospital
Esophagectomy, Pneumonectomy
Stellate Ganglion Block
The purpose of this study is to determine if the addition of an ultrasound guided left sided stellate ganglion block with bupivacaine in patients undergoing esophagectomy, pneumonectomy, or lobectomy will result in lower rates of…
- Conditions
- Esophagectomy, Pneumonectomy, Lobectomy
- Trial name
- NCT06271707
- Testing
- 0.5% bupivacaine, Saline
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Minnesota
Esophageal Cancer, Sentinel Lymph Node
The Value of Indocyanine Green-guided Near-infrared Fluorescence Technology in Tracing Sentinel Lymph Nodes During Esophagectomy
Sentinel lymph nodes, as the primary site of tumor metastasis, play a pivotal role in assessing patient prognosis and planning subsequent treatment strategies.
- Conditions
- Esophageal Cancer, Sentinel Lymph Node, Lymphadenectomy, Indocyanine Green
- Trial name
- NCT07303231
- Testing
- Minimally invasive surgery for esophageal cancer using near-infrared indocyanine green fluorescence to visualize the sentinel lymph node
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Fujian Medical University Union Hospital
Anastomotic Leak Esophagus
OBSiDiAN in a Stapled Circular Esophagogastric Anastomosis After Ivor Lewis Esophagectomy
Oesophagectomy is very invasive surgery. A leakage at the level of the connection between oesophagus and stomach made during surgery causes a lot more problems and can lead to death.
- Trial name
- Obsidian ph II (NCT05713955)
- Testing
- Obsidian
- Where
- 2 sites in Belgium
- Volunteers
- 90 people
- Sponsor
- University Hospital, Ghent
Esophageal Cancer
Perioperative SDD to Prevent Infectious Complications After Esophagectomy
The primary aim of the PERSuaDER-trial is to evaluate the effect of SDD on infectious complications after esophagectomy, focussed on the prevention of pneumonia
- Trial name
- PERSuaDER (NCT05865743)
- Testing
- SDD
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 854 people
- Sponsor
- Radboud University Medical Center
Esophageal Cancer
Value of Pleural Lavage Cytology in Resectable Esophageal Carcinoma Eastern Cooperative Thoracic Oncology Projects 2005, ECTOP-2005)
Disease recurrence and metastasis are common after curative treatment for patients with esophageal cancer. Thus, it is important to identify the risk factors to predict disease recurrence and metastasis.
- Trial name
- ECTOP-2005 (NCT05443841)
- Testing
- pleural lavage
- Where
- 11 sites in China
- Volunteers
- 385 people
- Sponsor
- Fudan University