Clinical trials: Erectile Dysfunction Following Radical Prostatectomy
Erectile Dysfunction
A Study of Tadalafil After Radical Prostatectomy
The study will include patients with localized prostate cancer who experience erectile dysfunction following bilateral nerve-sparing radical prostatectomy.
- Trial name
- REACTT (NCT01026818)
- Testing
- Tadalafil
- Where
- 52 sites in Belgium, Canada and 8 more
- Volunteers
- 583 people
- Sponsor
- Eli Lilly and Company
Prostate Cancer, Prostatectomy
BioDFence® G3 For Full Nerve-Sparing Robotic-Assisted Radical Prostatectomy
The purpose of this study is to assess functional outcomes post operatively after the use of BioDFence® G3 during robotic radical prostatectomy.
- Conditions
- Prostate Cancer, Prostatectomy, Erectile Dysfunction Following Radical Prostatectomy, Incontinence, Urinary
- Trial name
- NCT05363644
- Testing
- BioDFence G3
- Where
- United States
- Sponsor
- AdventHealth
Prostate Cancer
Nerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate Cancer
RATIONALE: Nerve-sparing radical prostatectomy with nerve grafting followed by standard therapies for erectile dysfunction may be effective in helping patients with prostate cancer improve sexual satisfaction and quality of life.
- Trial name
- NCT00080808
- Testing
- Alprostadil (E1), Papaverine, Phentolamine mesylate
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy
Sexual Dysfunction and Adaptation in Couples Affected by Prostate Cancer Surgery
The purpose of this study is to explore patient and partner experiences with sexual dysfunction following radical prostatectomy, in order to understand its effects on sexual and non-sexual intimacy.
- Conditions
- Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy, Sexual Dysfunction
- Trial name
- NCT00335634
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University Health Network, Toronto
Post Operative Recovery
Continence and Potency Following Multi-Layer Perinatal Issue alloGraft
The purpose of this research is to determine the effectiveness of using human Umbilical Cord (UC) allograft to help improve return to erectile function and bladder control in patients following robot-assisted radical…
- Trial name
- NCT05081232
- Testing
- MLG (Multi-Layered Perinatal Issue Allograft) Allograft
- Sponsor
- Wake Forest University Health Sciences
Erectile Dysfunction Following Radical Prostatectomy
The Use of Bioelectrical Stimulation in the Treatment of Post-prostatectomy Erectile Dysfunction
Erectile dysfunction (ED) affects up to 20% of men and is a growing problem with advancing age. There are many causes that contribute to ED, including the concomitant use of prescription drugs for health problems, including…
- Trial name
- NCT05118607
- Testing
- IG1
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Erectile Dysfunction Following Radical Prostatectomy
Low Intensity Shock-wave Therapy (Li-ESWT) in Penile Rehabilitation After Radical Prostatectomy
Erectile dysfunction (ED) is reported in up to 85% of men who have undergone a radical prostatectomy for prostate cancer. A few small studies have recently shown that low-intensity shockwave therapy may improve sexual performance…
- Trial name
- LiST-PRP (NCT03862599)
- Testing
- Extra-corporeal shockwave therapy (ESWT), Standard care
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Erectile Dysfunction Due to General Medical Condition, Erectile Dysfunction Following Radical Prostatectomy
Platelet Rich Plasma (PRP) as Terapeutical Option in Erectil Disfunction (DE)
Patients are randomized into 2 groups (A and B), subsequently group A is subjected to a cycle of 6 weekly injections of 3 ml of autologous PRP while group B is subjected to 6 weekly injections of 1 ml of caverject (alprostadil)…
- Conditions
- Erectile Dysfunction Due to General Medical Condition, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus, Erectile Dysfunctions
- Trial name
- NCT06768177
- Testing
- PRP injection, Alprostadil 20 micrograms
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy
Tractography-Guided Nerve-Sparing in Prostate Cancer
Radical prostatectomy (RP) is an effective treatment leading to a high rate of oncological control. However, despite advances in robot-assisted RP, the genito-urinary function, especially erectile function and urinary continence…
- Conditions
- Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy, Urinary Incontinence Following Surgical Procedure
- Trial name
- PRO-TRACT (NCT07847385)
- Testing
- Prostate Tractography for Nerve-Sparing
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- Massimo Valerio
Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction
Safety, Tolerability and Pharmacokinetics (PK) Evaluation of BZ371A, Topically Administered
The purpose of this study is to evaluate pharmacokinetics, safety and tolerability profile of BZ371A topically administered in healthy patients.
- Conditions
- Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction, Prostate Cancer, Radical Prostatectomy
- Trial name
- NCT05332340
- Testing
- BZ371A
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Biozeus Biopharmaceutical S.A.
Erectile Dysfunction Due to Arterial Insufficiency, Erectile Dysfunction
Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic Pain
The purpose of this study to perform a randomized, sham controlled analysis of the effectiveness of both fSWT and rWT in the relief of erectile dysfunction and chronic pelvic pain syndrome.
- Conditions
- Erectile Dysfunction Due to Arterial Insufficiency, Erectile Dysfunction, Erectile Dysfunction Due to Arterial Disease, Chronic Pelvic Pain Syndrome
- Trial name
- Shockwave (NCT05868668)
- Testing
- Focused shockwave, Radial wave
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- The Cleveland Clinic
Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy
A Study Looking at a New Nerve Surgery to Help Men Regain Erections After Prostate Cancer Surgery
A single arm prospective pilot trial evaluating the 1-year erectile recovery outcomes and the safety of patients undergoing a somatic to autonomic nerve grafting procedure for restoration of erectile function in patients who have…
- Trial name
- PRP NG PRO M (NCT07188064)
- Testing
- Post radical prostatectomy nerve restoration procedure (PRP-NR)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Prostate Cancer, Incontinence
Validating the 'Sexual Minorities and Prostate Cancer Scale' to Gold Standard Questionnaires
A cohort study comparing the novel 'Sexual Minorities and Prostate Cancer Scale' (SMACS) to the gold standard questionnaires investigating erectile dysfunction (IIEF) and incontinence (ICIQLUTSqol and ICIQ-UI) following robotic…
- Conditions
- Prostate Cancer, Incontinence, Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- SMACS (NCT05772598)
- Where
- United Kingdom
- Volunteers
- 305 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Incontinence, Erectile Dysfunction Following Radical Prostatectomy
Additional Effects of Aerobic and Resistance Exercises to Pelvic Floor Muscle Training After Radical Prostatectomy
In the literature, studies about urinary symptoms after radical prostatectomy (RP) are generally focused on urinary incontinence (UI), and studies about sexual symptoms are focused on erectile dysfunction (ED).
- Trial name
- NCT06126874
- Testing
- Patient Education, Pelvic Floor Muscle Training, Aerobic Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Hacettepe University
Erectile Dysfunction Following Radical Prostatectomy
Safety and Tolerability of a Novel Implantable Device for the Treatment of Erectile Dysfunction
The goal of this clinical trial is to assess if a new device is safe to use as a potential treatment for erectile dysfunction following radical prostatectomy.
- Trial name
- NCT05650866
- Testing
- Activation of pro-erectile nerves within the pelvic plexus
- Where
- 4 sites in Australia
- Volunteers
- 20 people
- Sponsor
- Comphya Australia
Humans, Urinary Incontinence
Intraoperative Nerve Monitoring During Robotic-assisted Radical Prostatectomy
The purpose of this study is to evaluate whether the use of intraoperative nerve monitoring during robotic-assisted radical prostatectomy (RARP) can predict and improve post-surgery urinary continence and erectile function.
- Conditions
- Humans, Urinary Incontinence, Male Urogenital Diseases, Prostatectomy
- Trial name
- NCT03721029
- Testing
- Intraoperative nerve monitoring,, standard of care robotic-assisted radical prostatectomy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Prostate Cancer, Erectile Dysfunction
Erythropoietin to Enhance Recovery of Erectile Function in Men Following Radical Prostatectomy
This research study aims to explore the effectiveness of human erythropoietin versus placebo in promoting the recovery of erectile function in patients undergoing bilateral nerve-sparing radical retropubic prostatectomy for…
- Trial name
- ERECT (NCT00737893)
- Testing
- Erythropoietin (EPO)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Johns Hopkins University
Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy
Penile Implant Intraoperative Measurements Planning Chart
This is a chart of penile size measurements where penile length and width are recorded intra-operatively prior to penile prosthesis implantation to guide the surgeon to the correct and adequate post-operative penile size
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction With Diabetes Mellitus, Erectile Dysfunction Due to Arterial Disease
- Trial name
- PIIMP (NCT05531877)
- Testing
- Penile Prosthesis Implantation
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Erectile Dysfunction Following Radical Prostatectomy
MED3000 Topical Gel for On-Demand Treatment of Post-Radical Prostatectomy Erectile Dysfunction
The investigators are doing this research to evaluate the efficacy and safety of topical MED3000 therapy in men with persistent erectile dysfunction 1.5 to 4 years following radical prostatectomy surgery.
- Trial name
- NCT05673005
- Testing
- MED3000 topical gel
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Erectile Dysfunction
Low Intensity Shock Wave Therapy in the Rehabilitation Treatment of Erectile Dysfunction After Robotic Radical Prostatectomy.
The study deals with the hypothesis that LiESWT in addition to the administration of PDE5i can improve sexuality rehabilitation with faster recovery of a valid erection and higher IIEF-5 scores in the short and medium-term…
- Trial name
- NCT06442020
- Testing
- Tadalafil (PDE5i)
- Where
- Italy
- Volunteers
- 158 people
- Sponsor
- Regina Elena Cancer Institute