Clinical trials: Erectile Dysfunction, pill or tablet or capsule or oral, open to volunteers
- Condition Erectile Dysfunction
- Drug or intervention pill OR tablet OR capsule OR oral
- Status Open to volunteers
Prostate Cancer, Localized Prostate Carcinoma
Erectile Function PRESERVation in Definitive Radiotherapy for Prostate Cancer by MRI-Enhanced Adaptive Sparing of the Neurovascular Bundle
Radiotherapy is a standard and highly effective treatment for prostate cancer that is confined to the prostate gland. One modern approach, called stereotactic body radiotherapy (SBRT), delivers treatment in just five sessions and…
- Conditions
- Prostate Cancer, Localized Prostate Carcinoma, Low-Risk Prostate Cancer, Intermediate-risk Prostate Cancer
- Trial name
- EF-PRESERVE (NCT07916779)
- Testing
- Daily Adaptive MR-Enhanced SBRT with Neurovascular Bundle Sparing
- Where
- Switzerland
- Volunteers
- 48 people
- Sponsor
- University of Zurich
Erectile Dysfunction
Effect of Moderate Alcohol on Absorption and Onset of Hezkue Sildenafil Suspension
This is a Phase 2, open-label, randomized crossover study assessing the effect of moderate alcohol intake on the absorption and onset of action of Hezkue® sildenafil oral suspension in adult subjects.
- Trial name
- NCT07290400
- Testing
- Hezkue Sildenafil Oral Suspension, Moderate Alcohol Intake
- Volunteers
- 36 people
- Sponsor
- Aspargo Labs, Inc
Erectile Dysfunction With Diabetes Mellitus
Evaluation of Efficacy of Botulinum Toxin A Plus Oral Tadalafil 5 mg in Diabetic Men With Erectile Dysfunction
Study is aiming to evaluate safety, efficacy and durability of intracavernosal injection (ICI) of Botulinum toxin A plus oral tadalafil in controlled diabetic men with refractory Erectile Dysfunction.
- Trial name
- NCT06583590
- Testing
- Botulinum toxin A, Tadalafil 5mg
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Aswan University Hospital
Erectile Dysfunction
Phase 2 Efficacy Study of Sildenafil Products in Adult Men With Erectile Dysfunction
The goal of this clinical trial is to learn how different sildenafil-based erectile dysfunction (ED) treatments affect erectile function in adult men.
- Trial name
- NCT07231185
- Testing
- Hezkue, Hezkue Turbo, Galotam
- Volunteers
- 200 people
- Sponsor
- Aspargo Labs, Inc
Erectile Dysfunction Associated With Type 2 Diabetes Mellitus
Daily Tadalafil in Diabetic ED Patients
This study evaluates the effect of 5 mg daily tadalafil therapy on serum levels of Endothelin-1 and E-selectin in diabetic male patients with erectile dysfunction.
- Trial name
- NCT06962462
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- South Valley University
Hypogonadism, Male, Secondary Hypogonadism
AIM-TEST: Microbiome-Targeted Nutrition for Functional Secondary Hypogonadism
AIM-TEST is a randomized, double-blind, placebo-controlled clinical trial evaluating whether an AI-guided, microbiome-targeted nutritional intervention can increase the body's own testosterone production in men aged 30-65 years…
- Trial name
- AIM-TEST (NCT07761546)
- Testing
- Fixed-Formula Microbiome-Targeted Oral Nutritional Supplement
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Varol TUNALI
Vasculogenic Erectile Dysfunction
Endothelial Markers and Tadalafil Response
This prospective cohort study will recruit eligible men attending the Urology/Andrology outpatient clinic. Baseline assessment will include demographic and clinical data, cardiovascular risk assessment, erectile-function…
- Trial name
- NCT07773103
- Testing
- Tadalafil 5mg
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer
Multimodal Prehabilitation and Rehabilitation for Men Undergoing Robot-Assisted Radical Prostatectomy
Prostate cancer is the most common cancer in Australian men. Robot-assisted radical prostatectomy (RARP) - surgical removal of the prostate - is a standard treatment, but it frequently causes erectile dysfunction (ED) and urinary…
- Conditions
- Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer, Urinary Incontinence Following Surgical Procedure
- Trial name
- ROBOPREP (NCT07576335)
- Testing
- Tadalafil 5 mg, Pelvic Floor Muscle Training (PFMT), Aerobic Exercise Program
- Where
- 3 sites in Australia
- Volunteers
- 64 people
- Sponsor
- Surgical Outcomes Research Centre (SOuRCe)
Erectile Dysfunction
The Objective of This Phase 1 Study is to Evaluate the Food Effect of 100 mg Hezkue Turbo® (ASP-001.1, Sildenafil) Under Fed Versus 100 mg of Hezkue Turbo® (ASP-001.1, Sildenafil) Under Fasted Conditions in Healthy Adult Male Subjects
The objective of this phase 1 study is to evaluate the food effect of 100 mg Hezkue Turbo® (ASP-001.1, sildenafil) under fed versus 100 mg of Hezkue Turbo® (ASP-001.1, sildenafil) under fasted conditions in healthy adult male…
- Trial name
- NCT06872866
- Testing
- ASP-001.1
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aspargo Labs, Inc
Nerve Injury, Prostate Cancer
4-aminopyridine Treatment for Nerve Injury
To evaluate the role of 4-aminopyridine (4-AP) on the course of recovery after peripheral nerve traction and/or crush injury. This study aims to test the hypothesis that 4-aminopyridine speeds the often slow and unpredictable…
- Trial name
- NCT03701581
- Testing
- 4-Aminopyridine
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- John Elfar
Erectile Dysfunction
Hezkue®, Hezkue Turbo®, and Commercial Sildenafil Products in Fed Healthy Male Subject
The goal of this clinical trial is to compare how different sildenafil formulations are absorbed and tolerated in healthy adult males under fed conditions.
- Trial name
- NCT07117383
- Testing
- ASP-001.1, ASP-001, Commercial Sildenafil and Sildenafil/Tadalafil Products
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Aspargo Labs, Inc
Prostatic Hyperplasia, Benign, Erectile Dysfunction
Efficacy and Safety of the DTT106 in the Treatment of Erectile Dysfunction Associated With Benign Prostatic Hyperplasia
The purpose of this study is to assess the safety and efficacy of the DTT106 in the treatment of erectile dysfunction associated with benign prostatic hyperplasia
- Trial name
- AUSTRÁLIA (NCT06264414)
- Testing
- DTT106, Dutasteride-Tamsulosin
- Where
- Brazil
- Volunteers
- 262 people
- Sponsor
- EMS
Erectile Dysfunction, Tadalafil
Daily Tadalafil as Adjunctive Therapy Versus Monotherapy for PDE5 Inhibitor-Resistant Erectile Dysfunction
This randomized trial will compare daily tadalafil 5 mg as adjunct therapy versus monotherapy in men with on-demand PDE5 inhibitor-resistant erectile dysfunction.
- Trial name
- NCT07753720
- Testing
- Tadalafil; Current on-demand PDE5 inhibitor, Tadalafil 5 mg
- Where
- Egypt
- Volunteers
- 260 people
- Sponsor
- Al-Azhar University
Erectile Dysfunction
L-Citrulline and Tadalafil for Mild to Moderate Erectile Dysfunction
Erectile dysfunction is a common male sexual health problem that may affect quality of life and sexual relationships. Tadalafil 5 mg once daily is an established oral treatment for erectile dysfunction.
- Trial name
- NCT07642505
- Testing
- L-Citrulline, Tadalafil
- Where
- Egypt
- Volunteers
- 133 people
- Sponsor
- Beni-Suef University
Erectile Dysfunction Following Radical Prostatectomy
Intracavernosal Exosomes vs. Rectal Ozone for Post-RARP Erectile Dysfunction
This prospective, randomized, controlled trial aims to evaluate and compare the therapeutic efficacy of intracavernosal urine-derived exosomes and systemic rectal ozone therapy in patients experiencing erectile dysfunction (ED)…
- Trial name
- REHAB-RARP (NCT07707505)
- Testing
- Urine-Derived Exosomes (USC-Exos), Rectal Medical Ozone Insufflation, Daily Phosphodiesterase type 5 (PDE5) Inhibitor
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Erectile Dysfunctions, Healthy Volunteer
A Study to Assess the Safety, Tolerability and Pharmacokinetics of Viaca (Sildenafil + Cabergoline) Compared With Sildenafil and Cabergoline
This is a Phase 1, open-label, single-ascending-dose study evaluating the safety, tolerability, and pharmacokinetics (PK) of Viaca - a fixed-dose oral combination of sildenafil (a PDE5 inhibitor) and cabergoline (a dopamine D2…
- Trial name
- NCT07732387
- Testing
- Viaca, Sildenafil 50 mg, Cabergoline 0.5 MG
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yanping Kong
Erectile Dysfunction
Study to Compare the Effects of Viagra® Vs Hezkue® in Healthy Fasted Male Participants.
The objective of this phase 1, open-label, single-center, two-way crossover trial is to evaluate the pharmacokinetics (PK), safety, and tolerability of 100 mg ASP-001 oral liquid suspension versus 100 mg Viagra (sildenafil…
- Trial name
- NCT06782659
- Testing
- ASP-001, Viagra
- Where
- 2 sites in United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Aspargo Labs, Inc
Erectile Dysfunction
A Study to Evaluate Efficacy and Safety of HIP2602 in Erectile Dysfunction Patients
A Multicenter, Randomized, Double-blind, Phase Ⅲ Study to Evaluate Efficacy and Safety of HIP2602 in Erectile Dysfunction Patients
- Trial name
- NCT07899073
- Testing
- HIP2602 + HPP2602-2, HPP2602-1 + HPP2602-2, HGP1201 + HPP2602-1
- Where
- South Korea
- Volunteers
- 225 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Prostate Cancer (Adenocarcinoma)
REDI-CaP(Recovery of Erectile Dysfunction Induced in Prostate Cancer Patients)
The goal of this study is to evaluate the recovery of erectile function at six months after hormonal therapy cessation in male patients affected by advanced prostate cancer and undergoing radiotherapy.
- Trial name
- REDI-CaP (NCT07302451)
- Testing
- Combined Androgen Deprivation Therapy with Relugolix and Image-Guided Stereotactic Body Radiotherapy (SBRT)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute, Naples