Clinical trials: Epilepsy
Headache, Epilepsy
Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients
Angiographies of the supra-aortic vessels by magnetic imaging have become common recently. So it was the purpose of this study to evaluate the imaging potential of different contrast agents.
- Conditions
- Headache, Epilepsy, Dizziness
- Trial name
- NCT00132223
- Testing
- Contrast agent
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- University Hospital Muenster
Epilepsy, Behavioral Disturbance
Compare Tolerability of an Overnight Switch to Gradual Switch Between Two Different Forms of Depakote
The hypothesis is that the characteristics of extended release Depakote will allow overnight conversion of immediate release to extended release form of Depakote.
- Trial name
- NCT00312676
- Testing
- Rapid versus slow conversion
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Veterans Affairs Medical Center, Miami
Parkinson's Disease, Epilepsy
Cohorts and Collections: Clinical and Genetic Study of Parkinson's Disease and Epilepsies
The DNA and Cell Bank of Instituts Federatifs de Recherche (IFR) of Neurosciences has been running for the last 15 years at the Institut National de la Santé Et de la Recherche Médicale (INSERM) Unit 679 (former unit 289).
- Trial name
- NCT00142363
- Where
- 15 sites in France
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Epilepsies, Partial
Effectiveness Study Comparing Treatment With Drug(s) or Adjunctive VNS Therapy for Pharmacoresistant Partial Seizures
To compare outcomes over 12 months of treatment with antiepileptic drugs (AEDs) alone or vagus nerve stimulation (VNS) therapy plus AEDs in patients who have partial seizures refractory to at least two, but not more than five…
- Trial name
- NCT00215215
- Testing
- Vagus Nerve Stimulation Therapy
- Where
- 23 sites in United States
- Volunteers
- 360 people
- Sponsor
- Cyberonics, Inc.
Epilepsy
Efficacy of Modified Ketogenic Diet (Atkins) in Management of Epilepsy
The purpose of this study is to determine whether patients with uncontrolled epilepsy can follow a low carbohydrate diet long-term and if so, how will that diet affect their seizures
- Trial name
- NCT00188500
- Testing
- atkins diet, ability to follow low carbohydrate diet
- Where
- Canada
- Sponsor
- University Health Network, Toronto
Epilepsy
Study to Improve the Treatment of Epilepsy (SITE)
The purpose of this study is to assess whether changing antiepileptic medication can reduce side effects and improve the quality of life in patients with epileptic seizures that are well controlled with antiepileptic drugs.
- Trial name
- NCT00133081
- Testing
- All registered antiepileptic drugs
- Where
- 6 sites in Netherlands
- Volunteers
- 255 people
- Sponsor
- UMC Utrecht
Migraine With Typical Aura
Study With Migraid Device in Acute, Early Treatment of Migraine With Typical Aura
The purpose of the study was to assess the efficacy of Migraid in terms of preventing headaches in patients with migraine with typical aura.
- Trial name
- NCT00126035
- Testing
- Migraid
- Where
- Netherlands
- Volunteers
- 134 people
- Sponsor
- Profess Medical Consultancy
Status Epilepticus
Phase III Randomized Study of Diazepam Vs Lorazepam Vs Placebo for Prehospital Treatment of Status Epilepticus
OBJECTIVES: I. Compare the efficacy, onset of clinical anticonvulsant activity, and complications of diazepam and lorazepam given intravenously as prehospital therapy to patients in status epilepticus. II.
- Trial name
- NCT00004297
- Testing
- diazepam, lorazepam
- Volunteers
- 210 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Epilepsy
Double-Blind, Placebo-Controlled Trial of Vitamin E as Add-on Therapy for Children With Epilepsy
This is a study to see if vitamin E helps children with epilepsy have fewer seizures. About 20-30% of children with epilepsy do not have adequate seizure control with established antiepileptic drugs (AEDs).
- Trial name
- NCT00004637
- Testing
- Vitamin E
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)
Spasms, Infantile, Epilepsy
Phase II Randomized Study of Early Surgery Vs Multiple Sequential Antiepileptic Drug Therapy for Infantile Spasms Refractory to Standard Treatment
OBJECTIVES: I. Evaluate the efficacy of surgical resection of an identifiable zone of cortical abnormality versus multiple drug therapy in children with infantile spasms refractory to standard therapy. II.
- Trial name
- NCT00004758
- Testing
- carbamazepine, corticotropin, nitrazepam
- Volunteers
- 30 people
- Sponsor
- National Center for Research Resources (NCRR)
Lennox-Gastaut Syndrome
Phase III Randomized, Double-Blind, Placebo-Controlled Study of Oral Topiramate for Lennox-Gastaut Syndrome
OBJECTIVES: I. Evaluate the safety and efficacy of oral topiramate in patients with Lennox-Gastaut syndrome.
- Trial name
- NCT00004776
- Testing
- topiramate
- Volunteers
- 10 people
- Sponsor
- National Center for Research Resources (NCRR)
Post-Traumatic Seizure Disorder, Head Injuries
Phase III Double Blind Trial of Valproate Sodium for Prophylaxis of Post Traumatic Seizures
OBJECTIVES: I. Determine whether treating head injured patients with valproate sodium will reduce the risk of developing seizures as a result of the head injury. II.
- Trial name
- NCT00004817
- Testing
- phenytoin, valproate sodium
- Volunteers
- 385 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Epilepsy
Genetic Study of Familial Epilepsy
OBJECTIVES: I. Determine the chromosomal regions that contain genes that raise the risk of epilepsy in families by performing genetic linkage analysis of idiopathic/cryptogenic epilepsy.
- Trial name
- NCT00006059
- Where
- United States
- Volunteers
- 898 people
- Sponsor
- National Center for Research Resources (NCRR)