Clinical trials: Epilepsy
Epilepsy
RCT of the Efficacy of the Ketogenic Diet in the Treatment of Epilepsy
A study of the efficacy and tolerability of two different ketogenic diets in children with drug resistant epilepsy; children resistant to at least two drugs randomised to reveive diet after baseline or after further 3m control…
- Trial name
- NCT00564915
- Testing
- Ketogenic diet
- Where
- United Kingdom
- Volunteers
- 145 people
- Sponsor
- Institute of Child Health
Epilepsy
Hormone Profiles in Adults With Newly Diagnosed Epilepsy
Both sodium valproate and lamotrigine are currently used in the treatment of newly diagnosed epilepsy. Although they appear to have similar efficacy, they have different side effects, which have not been well studied.
- Trial name
- NCT00137709
- Testing
- Sodium valproate, Lamotrigine
- Where
- 2 sites in Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Healthy, Parkinson Disease
PET Study of the Nicotinic Receptors in Human
The purpose of this study is to quantify the brain distribution of the nicotinic receptors in human volunteers and their alterations in patients suffering from neurological diseases such as Parkinson and Alzheimer diseases and…
- Conditions
- Healthy, Parkinson Disease, Alzheimer Disease, Epilepsy
- Trial name
- NCT00543322
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Commissariat A L'energie Atomique
Epilepsy
Study of Antiepileptic Drug Effects on Child Development
The specific aim of this study is to determine if in utero exposure produces differential antiepileptic drug (AED) effects on subsequent cognitive abilities and behavioral abnormalities in children
- Trial name
- NCT00353886
- Testing
- TONI-3, WRAT-3, Connor's Rating Scales PRS & TRS
- Where
- 10 sites in United States, United Kingdom
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Augusta University
Epilepsy
Role of Antibodies Against Glutamate Receptors and Double Stranded DNA in Epilepsy Patients
The investigators will check the serum of epilepsy patients for antibodies against glutamate receptors and double stranded DNA. They will characterise the patients (by the kind of epilepsy, autoimmune disease comorbidity, and…
- Trial name
- NCT00317668
- Where
- Israel
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Epilepsy
Pediatric Epilepsy Database
The purpose of this database is to collect information for clinical purposes on all children being treated for seizure disorders.
- Trial name
- NCT00204360
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Migraine, Photophobia
An Efficacy Study of a Single Dose Treatment of PRO-513 for Subjects Suffering a Migraine Attack
The purpose of the study is to show the efficacy of a single dose of PRO-513 for treating subjects suffering moderate pain form a migraine attack, with or without aura.
- Conditions
- Migraine, Photophobia, Phonophobia
- Trial name
- NCT00330850
- Testing
- PRO-513
- Where
- 16 sites in United States
- Volunteers
- 650 people
- Sponsor
- ProEthic Pharmaceuticals
Epilepsy
Observational Study of Lamotrigine
The purpose of this study is to assess efficacy, safety and tolerability of lamotrigine as used in a natural clinical setting, to examine the positive effects of lamotrigine, and the reasons why some patients choose to continue…
- Trial name
- NCT00299793
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwell Health
Traumatic Brain Injury, Cerebral Infarction
Characteristics of Blood- Brain Barrier Permeability in Neurological Patients
The main goal of the present study is to challenge the hypothesis that blood- brain barrier disruption following brain injury increases the risk for long-term disability, development of brain dysfunction, epileptic seizures and…
- Conditions
- Traumatic Brain Injury, Cerebral Infarction, Cerebral Hemorrhage
- Trial name
- NCT00419874
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Seizure Disorder, Partial
To Evaluate Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures.
To evaluate long-term safety and efficacy of pregabalin in patients with partial seizures.
- Trial name
- NCT00141245
- Testing
- Pregabalin
- Where
- 46 sites in Australia, Austria and 11 more
- Volunteers
- 325 people
- Sponsor
- Pfizer
Seizure Disorder, Partial
To Evaluate the Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures.
To evaluate the long-term safety and tolerability of pregabalin in patients with partial seizures.
- Trial name
- NCT00141336
- Testing
- Pregabalin
- Where
- 103 sites in United States, Canada
- Volunteers
- 750 people
- Sponsor
- Pfizer
Epilepsy, Partial
To Evaluate the Long-Term Safety of Pregabalin in Refractory Partial Epilepsy.
To evaluate the long-term safety of pregabalin in refractory partial epilepsy.
- Trial name
- NCT00141414
- Testing
- Pregabalin
- Where
- 25 sites in United States, Germany
- Volunteers
- 82 people
- Sponsor
- Pfizer
Epilepsy
Prediction of Childhood Epilepsy Outcome in Bangladesh
Randomised controlled trial of the use of phenobarbitone and carbamazepine in childhood epilepsy in Bangladesh with particular reference to behavioural side effects.
- Trial name
- NCT00381537
- Testing
- phenobarbitone, carbamazepine
- Where
- 2 sites in Bangladesh, United Kingdom
- Volunteers
- 92 people
- Sponsor
- Institute of Child Health
Epilepsy, Seizures
Ketogenic Diet for Child Epilepsy and Seizure Control
Twenty to thirty percent of children with epilepsy continue to suffer from seizures, even when treated with currently available anticonvulsant medications.
- Conditions
- Epilepsy, Seizures, Lennox-Gastaut Syndrome
- Trial name
- NCT00004729
- Testing
- Ketogenic diet
- Where
- United States
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Epilepsy
Mapping of the Epileptic Brain
This study aims improving the outcome after brain resective surgery of epileptic patients by improving presurgical evaluations. In particular the specific goal is to evaluate the ability of non invasive neuroimaging (functional…
- Trial name
- NCT00405145
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Epilepsy
Neonatal Brain Waves After Electrocoagulation
Electrocoagulation effect of neonatal brain waves after cesarean section
- Trial name
- NCT00396773
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Adults With Tonic Clonic Seizures and/or Partial Seizures
Second-Line Treatment Choice for Epilepsy
Most patients are prescribed valproate as their first antiepileptic drug. It is unknown which is the best second-line drug when patients do not become seizure free on valproate.
- Trial name
- NCT00208520
- Testing
- Carbamazepine, Lamotrigine, Levetiracetam
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Dutch Epilepsy Clinics Foundation
Partial Seizure Disorder
A Study of the Safety and Efficacy of Depakote Sprinkle Capsules in the Treatment of Partial Seizures in Children
The purpose of this study is to compare the safety and efficacy of two concentration ranges of valproate using Depakote Sprinkle Capsules as adjunctive therapy in the treatment of partial seizures, with or without secondary…
- Trial name
- NCT00067431
- Testing
- Divalproex Sodium (Depakote® Sprinkle Capsules)
- Where
- 7 sites in United States
- Volunteers
- 300 people
- Sponsor
- Abbott
Epilepsies, Partial, Epilepsy, Complex Partial
Pregabalin Open-Label Extension Trial in Patients With Partial Seizures
The primary purpose of the protocol is to evaluate the long-term safety of pregabalin in patients with partial seizures.
- Trial name
- NCT00143143
- Testing
- Pregabalin
- Where
- 47 sites in Austria, Canada and 6 more
- Volunteers
- 300 people
- Sponsor
- Pfizer
Menopause, Epilepsy
Hormone Replacement in Menopausal Women With Epilepsy
The goal of this study is to evaluate the effect of synthetic hormone replacement therapy on anti-seizure medication levels, menopausal symptom relief, and seizure frequency and safety in menopausal women with epilepsy.
- Trial name
- NCT00027209
- Testing
- prempro
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)