Clinical trials: Epidural Analgesia, open to volunteers
Analgesia Obstetrical, Analgesia
Intrathecal Versus Epidural Morphine for Post-Cesarean Analgesia
Cesarean section is one of the most commonly performed surgical procedures worldwide, making effective management of acute postoperative pain a key issue in obstetric anesthesiology.
- Conditions
- Analgesia Obstetrical, Analgesia, Post Operative Pain, Patient Satisfaction
- Trial name
- NCT07386353
- Testing
- Intrathecal Morphine, Epidural Morphine
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospital Central do Funchal
Labour Pain
Spoken Animation for Labour Epidural
The purpose of this study is to evaluate a new animated information film as a tool for introducing the concept of epidural as a method of labour pain relief to expectant women.
- Trial name
- SALE (NCT07202221)
- Testing
- Participant views Epidural animation before reading gold standard written information, Participant receives current gold standard written information alone
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Caudal Epidural Anesthesia, Erector Spinae Plane Block
Comparison of Erector Spinae Plane Block and Caudal Block in Pediatric Patients Aged 1 to 8 Years Undergoing Lower Abdominal Surgery
In routine pediatric surgical practice, lower abdominal surgeries are commonly performed. Inadequate control of postoperative pain can hinder functional recovery and may lead to negative behavioral changes as well as parental…
- Conditions
- Caudal Epidural Anesthesia, Erector Spinae Plane Block, Pediatric
- Trial name
- NCT07426939
- Testing
- caudal block, Erector Spinae Plane Block
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Awake, Thoracic Epidural Anesthesia
Awake Thoracic Epidural Anesthesia Versus General Anesthesia in Thoracotomy
This study aims to compare awake thoracic epidural anesthesia and general anesthesia in thoracotomy.
- Conditions
- Awake, Thoracic Epidural Anesthesia, General Anesthesia, Thoracotomy
- Trial name
- NCT06930183
- Testing
- Awake thoracic epidural anesthesia, General anesthesia
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Total Knee Anthroplasty, Epidural Analgesia
Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Postoperative Analgesia After Total Knee Arthroplasty
The goal of this clinical trial is to compare two different epidural analgesia delivery methods for pain control after total knee arthroplasty in adults undergoing elective surgery.
- Trial name
- NCT07605208
- Testing
- Programmed intermittent epidural bolus 6 ml, continuous epidural infusion
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sakarya University
Cesarean Section, Anesthesia, Obstetrical
Dural Puncture Epidural With 27G vs 26G Needles Versus Standard Epidural for Elective Cesarean Delivery
The goal of this clinical trial is to learn whether the dural puncture epidural (DPE) technique shortens the onset time of surgical anesthesia compared with the standard epidural technique in healthy women undergoing elective…
- Conditions
- Cesarean Section, Anesthesia, Obstetrical, Anesthesia, Epidural
- Trial name
- NCT07897045
- Testing
- Standard Epidural Anesthesia, Dural Puncture Epidural With 27G Spinal Needle, Dural Puncture Epidural With 26G Spinal Needle
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ankara City Hospital Bilkent
Labor, Obstetric, Epidural Analgesia, Obstetric
Integrated Intrapartum Supportive Care and Pushing Strategies in Women Receiving Low-Dose Epidural Analgesia
This prospective, three-arm, non-randomized quasi-experimental study aims to evaluate integrated intrapartum supportive care combined with different pushing strategies among women at 37-42 weeks of gestation who receive low-dose…
- Conditions
- Labor, Obstetric, Epidural Analgesia, Obstetric, Labor Duration
- Trial name
- NCT07663500
- Testing
- Integrated Care with Immediate Pushing, Integrated Care with Spontaneous Pushing Group, Standard Routine Care
- Where
- Taiwan
- Volunteers
- 159 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Epidural Analgesia, Obstetric, Maternal Satisfaction
Impact of Patient Choice for Epidural Potency on Maternal Satisfaction
This clinical trial will compare two different approaches to epidural analgesia during labor to see which approach leads to higher patient satisfaction after delivery.
- Trial name
- NCT07414407
- Testing
- Patient-selected epidural management, Standard epidural management
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Stanford University
Maternal Hypotension, Labor Epidural Analgesia
Maternal and Fetal Clinical Significance of Hypotension Following Labor Epidural Analgesia
The goal of this study is to learn how often blood pressure drops after an epidural for labor and how these drops may affect the parent and the baby.
- Conditions
- Maternal Hypotension, Labor Epidural Analgesia, Fetal Heart Rate Abnormalities
- Trial name
- NCT07272018
- Testing
- Epidural Analgesia (Standard Clinical Care)
- Volunteers
- 480 people
- Sponsor
- The Chaim Sheba Medical Center
Labor
Impact of Prophylactic Ephedrine on Fetal Heart Tracing and Uterine Tetanic Contraction After CSE
Labor analgesia is an important component of the care of laboring patients. A known side effect of combined spinal and epidural anesthesia (a type of labor analgesia) is an increased incidence of category II fetal heart rate…
- Trial name
- NCT05873218
- Testing
- Ephedrine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Colorectal Carcinoma, Analgesia, Postoperative
Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery
Effective pain management after abdominal surgery is essential for recovery. This study compares two pain relief methods-intrathecal morphine (a single spinal injection) and continuous epidural analgesia-for patients undergoing…
- Conditions
- Colorectal Carcinoma, Analgesia, Postoperative, Laparotomy
- Trial name
- NCT06935708
- Testing
- Intrathecal Morphine, Epidural Analgesia
- Where
- Croatia
- Volunteers
- 98 people
- Sponsor
- Meri Mirceta
Radiculopathy
Interest of the Virtual Reality as an Analgesic Support and in the Management the Pre-procedural Anxiety in Rheumatology
As a part of the current rheumatological practice skills, epidural injections through the sacrococcygeal hiatus take part in the strategy for managing radicular diseases.
- Trial name
- REAVIR (NCT05289999)
- Testing
- Virtual reality headset for first injection, Virtual reality headset for second injection
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier le Mans
Organ Dysfunction, Organ Support
Thoracic Epidural Analgesia for Acute Pancreatitis With Early Organ Dysfunction
Acute pancreatitis may cause early respiratory, cardiovascular, or renal dysfunction and may require intensive care and organ support.
- Conditions
- Organ Dysfunction, Organ Support, Acute Pancreatitis (AP)
- Trial name
- TEA-APOD (NCT07697690)
- Testing
- Thoracic Epidural Analgesia With Ropivacaine, conventional analgesia
- Volunteers
- 150 people
- Sponsor
- First People's Hospital of Chenzhou
Duodenal Neoplasm, Pancreatic Neoplasm
Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy
This phase II trial compares the effect of rectus sheath block with liposomal bupivacaine to thoracic epidural analgesia (TEA) on pain control in patients following surgical removal of all or part of the pancreas and duodenectomy…
- Trial name
- NCT06411795
- Testing
- Bupivacaine, Hydromorphone, Iopamidol
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Abdomen Cancer, Pancreas Adenocarcinoma (MSI-H)
Implementation of a Pain Management Plan in Major Open Abdominal Surgeries.
Introduction: Major abdominal surgery encompasses a broad range of surgical procedures in heterogeneous patient populations.Management of postoperative pain has received keen attention in recent years with considerable concurrent…
- Conditions
- Abdomen Cancer, Pancreas Adenocarcinoma (MSI-H), Colectomy Left/Right/Total Under Laparotomy, Hepatectomy
- Trial name
- NCT07901582
- Testing
- Epidural administered opioid
- Where
- Greece
- Volunteers
- 58 people
- Sponsor
- National and Kapodistrian University of Athens
Anesthesia, Analgesia
Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural
As the dural puncture epidural (DPE) is increasing in popularity for labor analgesia, it is important to understand how it impacts outcomes in parturients.
- Trial name
- NCT05514431
- Testing
- Epidural, Dural Puncture Epidural (DPE) technique, Combined Spinal-Epidural (CSE) technique
- Where
- 2 sites in United States, Canada
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Ventral Hernia, Ventral Hernia Repair
Epidural Analgesia Versus Opioid-sparing Analgesia for Open Ventral Hernia Repair With Transversus Abdominis Release
This study is comparing two ways to manage pain after a major hernia repair surgery called "transversus abdominis release." One method uses an epidural, a small tube placed in the back that delivers pain medicine directly around…
- Conditions
- Ventral Hernia, Ventral Hernia Repair, Postoperative Pain
- Trial name
- EASE-TAR (NCT07840183)
- Testing
- Bupivicaine, Fentanyl, Thoracic epidural analgesia
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwestern University
Postpartum Recovery, Mother-infant Bonding
Labor Epidural Analgesia and Mother-Infant Bonding After Vaginal Delivery
This prospective observational cohort study aims to evaluate the association between postpartum recovery quality and mother-infant bonding in women undergoing vaginal delivery.
- Conditions
- Postpartum Recovery, Mother-infant Bonding, Labor Pain
- Trial name
- NCT07582289
- Testing
- Labor Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ataturk University
Labor Analgesia, Labor Pain
Effect of Dural Puncture Epidural Analgesia on Oxytocin in Early vs Late Labor
Oxytocin is a key hormone that regulates uterine contractions during labor. Dural Puncture Epidural Analgesia (DPEA) is a modern technique for labor pain relief that provides faster onset and more reliable analgesia than standard…
- Conditions
- Labor Analgesia, Labor Pain, Oxytocin
- Trial name
- DPEA-OXY (NCT07873814)
- Testing
- Dural Puncture Epidural Analgesia (DPEA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Laparotomy
Influence of Analgesic Technique on Post Operative Rehabilitation After Median Laparotomy
Randomized controlled trial (1:1) in two parallel groups, multicentric, open-label, comparing two locoregional anesthesia (LRA) techniques as integral parts of multimodal analgesia: the control group will benefit from epidural…
- Trial name
- QORRECTCATH (NCT04985695)
- Testing
- Epidural analgesia, Bilateral rectus sheath block, Laparotomy
- Where
- 2 sites in France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville