Clinical trials: Epidural Analgesia
Labor Pain, Analgesia, Epidural
Comparing PIEB and CEI for Labor Pain Relief
The purpose of this randomized controlled trial is to compare the efficacy and safety of two epidural analgesia maintenance methods for labor pain relief: Programmed Intermittent Epidural Bolus (PIEB) and Continuous Epidural…
- Conditions
- Labor Pain, Analgesia, Epidural, Analgesia, Obstetrical, Labor, Obstetric
- Trial name
- COPILOT (NCT07395934)
- Testing
- PIEB + PCEA, CEI + PCEA
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Da Nang Family General Hospital
Local Analgesia Via Infiltration, Caudal Epidural Anesthesia
Perioperative Analgesia Using Ultrasound Guided Erector Spinae Block vs Ultrasound Guided Caudal Block for Pain Control in Children Aged 2-7 Years Undergoing Lower Abdominal Surgery
The goal of this prospective study is to is to evaluate the perioperative pain management of Erector Spinae Block versus Caudal Block using the Face, Legs, Activity, Cry, Conceal ability (FLACC) Pain Scale inn children aged 2 to…
- Conditions
- Local Analgesia Via Infiltration, Caudal Epidural Anesthesia, Caudal Block, Caudal Block for Postoperative Analgesia
- Trial name
- NCT07281235
- Testing
- Ultrasound Guided Bilateral single shot Erector Spinae Plane Block, Caudal Block Anesthesia
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Subcostal, Lateral
Combined Subcostal and Lateral Transversus Abdominis Plane Block for Postoperative Analgesia Versus Thoracic Epidural Analgesia in Patients Undergoing Major Abdominal Cancer Surgery
This study aims to evaluate the safety and efficacy of combined subcostal and lateral transversus abdominis plane (TAP) for postoperative analgesia versus thoracic epidural anesthesia (TEA) in patients undergoing major abdominal…
- Conditions
- Subcostal, Lateral, Transversus Abdominis Plane Block, Postoperative Analgesia
- Trial name
- NCT07273136
- Testing
- Subcostal and lateral transversus abdominis plane block, Thoracic epidural anesthesia
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Maternal Hypotension, Labor Epidural Analgesia
Maternal and Fetal Clinical Significance of Hypotension Following Labor Epidural Analgesia
The goal of this study is to learn how often blood pressure drops after an epidural for labor and how these drops may affect the parent and the baby.
- Conditions
- Maternal Hypotension, Labor Epidural Analgesia, Fetal Heart Rate Abnormalities
- Trial name
- NCT07272018
- Testing
- Epidural Analgesia (Standard Clinical Care)
- Volunteers
- 480 people
- Sponsor
- The Chaim Sheba Medical Center
Epidural Analgesia, Ultrasound Assistance
Impact of Ultrasound Guidance on Central Neuraxial Block Success in Patients With Non-Palpable Vertebral Anatomy
Patients scheduled to undergo general surgery with planned epidural catheter placement will be evaluated by comparing two different techniques routinely used in anesthesia practice for catheter insertion.
- Trial name
- NCT07269184
- Testing
- epidural catheter, ultrasonography, anatomic landmark, epidural cateterisation
- Volunteers
- 60 people
- Sponsor
- Sakarya University
To Compare Efficacy of Dexmedetomidine in Bilateral Quadratus Lumborum vs Lumbar Epidural Blocks on Analgesia After Major Lower Abdominal Surgery
Clinical Efficacy and Safety of Dexmedetomidine as an Adjuvant in Quadratus Lumborum Versus Epidural Block in Postoperative Lower Abdominal Cancer Surgeries
Clinical efficacy and safety of dexmedetomidine as an adjuvant in quadratus lumborum versus epidural block in postoperative patients
- Trial name
- NCT06130670
- Testing
- nerve block
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Pain Management, Video-assisted Thoracoscopic Surgery (VATS)
Analgesic Effectiveness of SPSIPB Versus Thoracic Epidural and Systemic Opioid Analgesia After VATS (SPSIPB-VATS)
This prospective observational study aims to compare the postoperative analgesic effectiveness of three commonly used pain management strategies in video-assisted thoracoscopic surgery (VATS): Serratus Posterior Superior…
- Conditions
- Postoperative Pain Management, Video-assisted Thoracoscopic Surgery (VATS), Thoracic Epidural Analgesia, Serratus Posterior Superior Intercostal Plane Block
- Trial name
- SPSIPB-VATS (NCT07238348)
- Volunteers
- 120 people
- Sponsor
- Karadeniz Technical University
Abdominal Surgery by Laparotomy, Thoracic Epidural Analgesia
Evaluation of Plasma Concentrations of Intravenous Lidocaine and Epidural Ropivacaine When Used in Combination in Major Abdominal Surgery
Thoracic epidural analgesia (TEA) is the gold standard analgesia of the laparotomy in major abdominal surgery and can be associated with intravenous lidocaine or subtituted by intravenous lidocaine when TEA is contraindicated and…
- Conditions
- Abdominal Surgery by Laparotomy, Thoracic Epidural Analgesia, Analgesia, Lidocaine Adverse Reaction
- Trial name
- LARA (NCT05368753)
- Testing
- Blood sample, Lidocain, ropivacaine
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Analgesia, Analgesia, Epidural
Postoperative Analgesia in Major Gynecological Cancer Surgeries
The aim of this study is to compare the effectiveness of epidural block or erector spinae plane block applied for postoperative analgesia in gynecological cancer surgeries.
- Conditions
- Analgesia, Analgesia, Epidural, ERAS
- Trial name
- NCT06424938
- Testing
- Patients who underwent epidural block, Patients who underwent erector spina plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Duygu Akyol
Medical Education, Resident Education
Impact of Mental Training on the Stress of Anaesthesiology Residents Before Performing Obstetrical Epidural Analgesia
Anaesthetists are trained from the beginning of their residency to perform high-risk procedures, often in high-stress environments, that can adversely affect both their technical and non-technical performance.
- Conditions
- Medical Education, Resident Education, Anesthesia, Epidural Analgesia, Obstetric
- Trial name
- NCT07183618
- Testing
- Mental training group
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Epidural Analgesia, Medical Education
Simulation-Based Training for Epidural Analgesia Placement
Epidural analgesia is the gold standard for labor pain management, widely recommended by the WHO and included in Italy's essential levels of care (LEA) since 2017.
- Conditions
- Epidural Analgesia, Medical Education, Obstetric Anesthesia
- Trial name
- NCT07056140
- Testing
- Epidural Simulation Training, Standard Clinical Training
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- University of Padova
Epidural Related Maternal Fever, Analgesia, Epidural
The Impact of Local Anesthetic Solution Temperature on Epidural-related Maternal Fever
This study investigates how the temperature of local anesthetics affects maternal fever related to epidural analgesia during childbirth.
- Conditions
- Epidural Related Maternal Fever, Analgesia, Epidural, Fever, Intrapartum Fever
- Trial name
- NCT06682416
- Testing
- In the context of epidural analgesia, the temperature of the local anesthetic solution is elevated to 37°C utilizing a blood transfusion and infusion warmer.
- Where
- 2 sites in China
- Volunteers
- 424 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Epidural Catheter, Epidural Analgesia
Epidural Anesthesia for Transurethral Resection of The Prostate
The aim of this study is to assess the effects of different routes of local anesthetic administration in epidural anesthesia applied to patients undergoing transurethral resection of the prostate (TUR-P).
- Conditions
- Epidural Catheter, Epidural Analgesia, Geriatric Cardiology, Urologic Disorders
- Trial name
- NCT06893809
- Testing
- Epidural injection via Tuohy needle, Epidural injection via catheter, Combined epidural injection (needle and catheter)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Pregnancy, Epidural Analgesia, Obstetric
Intelligence and Neurodevelopmental Outcome After Prenatal Exposure to Labour Epidural Analgesia: a Sibling Matched Clinical Ambidirectional Cohort Study
In Belgium, labour epidural analgesia (LEA) has been used for decades in the vast majority of vaginal deliveries (up to 83% of deliveries).
- Trial name
- NCT07014956
- Testing
- Labour epidural analgesia
- Where
- Belgium
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Epidural Analgesia, Obstetric
Impact of Low-Dose Epidural Analgesia on Labour Progression in Low-Risk Women
Aim of the study was to analyse data on cervical dilation and fetal descent patterns in low-risk women, who did or did not receive intermittent low-dose epidural analgesia (EA), and who had either a vaginal or a caesarean…
- Trial name
- NCT06987591
- Where
- Italy
- Volunteers
- 5,995 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Ultrasound, Multilevel Erector Spinae Plane Block
Ultrasound-guided Multilevel Erectorspinae Plane Block Versus Thoracic Epidural Analgesia for Prevention of Post Mastectomy Pain Syndrome for Breast Cancer Patients
The aim of this study is to compare the analgesic efficacy of multilevel erector spinae plane block (ESPB) vs thoracic epidural in modified radical mastectomy (MRM) regarding duration of analgesia, postoperative opioid…
- Conditions
- Ultrasound, Multilevel Erector Spinae Plane Block, Thoracic Epidural Analgesia, Post Mastectomy
- Trial name
- NCT06884852
- Testing
- Erector spinae plane block (ESPB), Thoracic epidural block
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- National Cancer Institute, Egypt
Post Operative Analgesia, Opioid Consumption, Postoperative
Intravenous Acetaminophen to Reduce Post-operative Opioid Consumption
Acetaminophen (Tylenol) is a commonly used medication after surgery to control pain. Tablets for oral use and suppositories for rectal use are the most frequently employed forms of acetaminophen after surgery.
- Conditions
- Post Operative Analgesia, Opioid Consumption, Postoperative, Acetaminophen, Abdominal Surgeries
- Trial name
- ACETAPOP (NCT06923540)
- Testing
- IV Acetaminophen
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Hepatectomy, Analgesia, Epidural
Bupivacaine Levels in Liver Resection Patients
Bupivacaine is a local anesthetic commonly used to manage postoperative pain. Liver resection patients typically have an epidural catheter placed preoperatively through which they receive a continuous infusion of bupivacaine and…
- Trial name
- NCT03145805
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Jessica Burjorjee, MD, FRCPC
Analgesia, Epidural
Comparison of Safety and Efficacy Between PIEB and CEI for Labour Epidural Analgesia
The goal of this clinical trial is to compare safety and efficacy of programmed intermittent epidural bolus (PEIB) and continuous epidural infusion (CEI) in parturients during active phase of labour.
- Trial name
- NCT06889285
- Testing
- Continuos epidural infusion, Programmed intermittent epidural bolus
- Where
- Malaysia
- Volunteers
- 76 people
- Sponsor
- Hospital Universiti Sains Malaysia
Labour Analgesia, Epidural Anaesthesia, Duration of Labour
Impact of Timing of Neuraxial Analgesia on Obstetric, Anesthesiologic and Neonatal Outcomes in Induced Labour
The aim of this observational study is to assess the effect of early labour analgesia on obstetric and neonatal outcomes in induced labour in primiparous women with a full-term pregnancy whose labour was induced with a Cook…
- Conditions
- Labour Analgesia, Epidural Anaesthesia, Duration of Labour, Labor, Induced
- Trial name
- TAIL (NCT06886555)
- Testing
- Epidural analgesia for labour pain
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia