Clinical trials: Epidural
Readiness to Discharge
Analgesia After Total Knee Arthroplasty: Peri-Articular Injection Versus Epidural + Femoral Nerve Blockade
There are 2 common ways to manage pain after total knee arthroplasty at our institution. Some patients receive an epidural analgesia, a femoral nerve block and pills for pain.
- Trial name
- PAI vs FNB (NCT01335542)
- Testing
- Peri-Articular Injection, Epidural Pathway (PCEA+FNB)
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Hospital for Special Surgery, New York
Labor Pain, Induced; Birth
Spinal Fentanyl or Epidural Analgesia in the Early First Phase of Induced Labor
A total of 60 parturients undergoing induction of labour will be consented to participate in the study where they will be randomized to receive either spinal fentanyl (20 µg) or epidural analgesia (fentanyl 100µg and lidocaine 80…
- Trial name
- NCT04645823
- Testing
- Fentanyl Citrate, Lidocaine 1% Injectable Solution
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Women's Hospital HUS
Surgery
A Factorial Trial of Ultrasound and Manometry to Improve the Success of Thoracic Epidural Placement
To investigate the use of ultrasound and manometry to increase the success rate of thoracic epidural placement. The use of ultrasound for lumbar epidural catheter placement is well established and is thought to assist in…
- Trial name
- USA-MAN-TE (NCT03559023)
- Testing
- Ultrasound Only, Manometry Only, Ultrasound Plus Manometry
- Where
- United States
- Volunteers
- 480 people
- Sponsor
- Oregon Health and Science University
Pyrexia, Abdominal Delivery
Combined Anesthesia for Labor and Maternal Temperature
Maternal intra-partum fever commonly complicates the process of labour. Its occurrence is often regarded as being synonymous with the presence of chorioamnionitis.
- Trial name
- feveranalg (NCT01078519)
- Testing
- Combined epidural and spinal anesthesia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Labor, Epidural Analgesia
Pulse Pressure Variability With Position Before EPIdural Analgesia
Fetal heart rate abnormalities are common. Miller et al. have demonstrated that new onset fetal heart rate abnormalities after initial labor epidural dosing occur more frequently in women with a low admission pulse pressure than…
- Trial name
- PP-PERI (NCT03126136)
- Testing
- Nicom (TM)
- Where
- 4 sites in France
- Volunteers
- 1 people
- Sponsor
- Hopital Foch
Pregnancy, Breech Presentation
The Effect of Combined Spinal-Epidural Analgesia on the Success of External Cephalic Version (ECV) for Breech Position
We aim to answer the clinical question: Does combined spinal-epidural analgesia improve the success rate of external cephalic version? We hypothesize that neuraxial analgesia (spinal or epidural analgesia) during version for…
- Trial name
- Version (NCT00565383)
- Testing
- Combined spinal-epidural analgesia, Intravenous fentanyl (50mcg)
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Northwestern University
Cesarean Section, Epidural; Anesthesia
Incidence and Factors Involving Cesarean Delivery After Epidural Analgesia for Labor
The rate of cesarean delivery after epidural analgesia for labor has not been reported in our institute. The aim of this study is to elucidate incidence of cesarean delivery in parturient whom received epidural analgesia.
- Trial name
- NCT04074005
- Where
- Thailand
- Volunteers
- 188 people
- Sponsor
- Mahidol University
Post-ERCP Acute Pancreatitis
Study of Effectiveness of Thoracic Epidural Analgesia for the Prevention of Acute Pancreatitis After ERCP Procedures
For 40 years, the post-ERCP (endoscopic retrograde cholangiopancreatography) pancreatitis has been the most frequent adverse effect of endoscopic transpapillary interventions.
- Trial name
- NCT01964066
- Testing
- ERCP, Thoracic epidural analgesia, Premedication
- Where
- Russia
- Volunteers
- 491 people
- Sponsor
- Volgograd State Medical University
Hypotension, Anesthesia; Adverse Effect, Spinal and Epidural
ONDANSETRON AND EFFECTIVE DOSE IN 50% OF SUBJECTS OF PROPHYLACTIC NOREPINEPHRINE INFUSIONS FOR PREVENTING SPINAL ANESTHESIA-INDUCED HYPOTENSION DURING CESAREAN DELIVERY
Spinal anesthesia is the preferred technique for elective cesarean section as per ASA guidelines. Hypotension is the main complication of this technique and is secondary to both sympatholysis and its associated decrease in…
- Conditions
- Hypotension, Anesthesia; Adverse Effect, Spinal and Epidural, Cesarean Section
- Trial name
- NCT04703088
- Testing
- Ondansetron 4 MG, 0.9% Saline
- Volunteers
- 60 people
- Sponsor
- Laval University
Itching Symptoms, Itching Caused by Epidural Use of Opioids
tDCS for Reducing the Incidence of OEI After Cesarean Section
Cesarean section is the most common obstetric surgery worldwide. Epidural anesthesia has become the preferred anesthesia method for cesarean sections due to its definite analgesic effect and minimal impact on mother and baby.
- Trial name
- NCT07569783
- Testing
- Transcranial direct current stimulation
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Affiliated Hospital of Nantong University
Spinal Stenosis Lumbar, Low Back Pain
Relief of Lumbar Spinal Stenosis Symptoms
The aim of this study was to compare the efficacy of caudal epidural steroid injection and caudal epidural pulsed radiofrequency stimulation in the relief of symptoms of lumbar spinal stenosis.
- Trial name
- NCT06393959
- Testing
- Caudal epidural pulsed radiofrequency, Caudal epidural steroid enjection
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Diskapi Teaching and Research Hospital
Transforaminal Epidural Injection, Dorsal Root Ganglion Stimulation
The Effect of Adding a Local Anesthetic to Transforaminal Epidural Injection in Cervical Disc Herniation.
The study is designed as a double-blind, prospective, randomized controlled trial. Blindness is ensured by having different researchers performing the interventional procedures and monitoring the pain diaries, thus preventing…
- Conditions
- Transforaminal Epidural Injection, Dorsal Root Ganglion Stimulation, Servical Disc Herniation
- Trial name
- NCT07397286
- Testing
- servical transforaminal epidural steroid injection with local anaesthetic, servical transforaminal epidural steroid injection without local anaesthetic
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Lumbar Disc Disease, Radiculopathy Lumbar
Patient Satisfaction During Lomber Transforaminal Epidural Steroid Injection: The Role of Sedation, Anxiety, and Pain
Transforaminal epidural steroid injection (TFESI) is a minimally invasive procedure commonly used for the management of lumbar radicular pain.
- Conditions
- Lumbar Disc Disease, Radiculopathy Lumbar, Radicular Pain
- Trial name
- NCT07495501
- Testing
- Fluoroscopy-guided lumbar transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Mersin University
Postoperative Pain, Thoracic Surgery Lung
Analgesic Efficacy and Hemodynamic Stability of Ultrasound-guided Thoracic Erector Spinae Plane Block Versus Thoracic Epidural Analgesia in Pediatric Thoracic Surgery: a Randomized Controlled Trial.
Thoracic surgery in children is considered a highly invasive procedure that significantly affects respiratory mechanics and cardiovascular function, resulting in substantial physiological disturbances during the perioperative…
- Conditions
- Postoperative Pain, Thoracic Surgery Lung, Thoracotomy Analgesia, Regional Anesthesia
- Trial name
- NCT07602179
- Testing
- Thoracic erector spinae plane block (ESPB), Thoracic epidural analgesia (TEA)
- Where
- Vietnam
- Volunteers
- 70 people
- Sponsor
- Nguyen Dang Thu
Labor Pain
3 Simple Questions to Predict Labor Pain and Epidural Analgesia Use in Parturients
Labor pain is complex to understand and challenging to define because of the interaction of multiple maternal and fetal factors.
- Trial name
- NCT02824302
- Testing
- Survey
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Breakthrough Pain
Comparison of Regimens MPIB, CIPCEA, PCEA
Epidural analgesia is the gold standard of pain relief for labour pain. Despite this, more than 50% of parturients continue to experience pain leading to suffering and increased caregiver workload.
- Trial name
- COLEUS (NCT02278601)
- Testing
- epidural delivery system, Ropivacaine, Fentanyl
- Where
- Singapore
- Volunteers
- 839 people
- Sponsor
- KK Women's and Children's Hospital
3 or More Rib Fractures
Optimal Method of Pain Management in Patients With Multiple Rib Fractures
Rib fractures are a common injury of trauma patients and can cause significant pain which, if inadequately treated, can lead to impaired breathing, lung collapse, and respiratory failure.
- Trial name
- NCT01401712
- Testing
- ON-Q® Pain Relief System, Thoracic epidural catheter
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Massachusetts General Hospital
Lumbar Radicular Pain, Artifical Intelligence
MRI-Based Artificial Intelligence Prediction of Fluoroscopic C-Arm Angles for Lumbar Transforaminal Epidural Steroid Injections
This study aims to prospectively evaluate the accuracy of artificial intelligence (AI) in predicting fluoroscopic C-arm oblique and craniocaudal angles from pre-procedural lumbar magnetic resonance (MR) images for lumbar…
- Trial name
- NCT07875855
- Testing
- AI based evaluation
- Volunteers
- 80 people
- Sponsor
- Marmara University
Traumatic Brain Injury
Rehabilitation Research and Training Center for Traumatic Brain Injury Interventions--Teen Online Problem Solving Study
This study will evaluate the effectiveness of an Internet-based psychosocial treatment in improving problem-solving, communication skills, stress management strategies, and coping among teens who have had a traumatic brain injury…
- Trial name
- RRTC--TOPS (NCT01042899)
- Testing
- Teen Online Problem Solving (TOPS), Teen Online Problem Solving--Teen Only (TOPS-TO), Internet Resources Comparison (IRC)
- Where
- 5 sites in United States
- Volunteers
- 153 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Obstetric Labor
Multicenter Study of Chloroprocaine Versus Ropivacaine for Epidural Labor Analgesia
Women requiring epidural labor analgesia were randomized into two groups, one with the local anesthetic chloroprocaine and the other with ropivacaine.
- Trial name
- NCT06472232
- Testing
- Chloroprocaine
- Volunteers
- 356 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University